Placental mesenchymal dysplasia - Revision history

Michael at 00:06, 19 May 2014

2014-05-19T00:06:46Z

← Older revision		Revision as of 00:06, 19 May 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = stem villi with edema (hydropic changes) and few blood vessels, paucivascular or avascular terminal villi
			\| Subtypes =
			\| LMDDx = [[placental villous immaturity]], [[fetal thrombotic vasculopathy]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[placenta]]
			\| Assdx = fetal demise, [[IUGR]]
			\| Syndromes = [[Beckwith-Wiedemann syndrome]]
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = very rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = [[partial hydatidiform mole]]
			\| Tx =
			}}
	'''Placental mesenchymal dysplasia''', abbreviated '''PMD''', is a very rare pathology of the [[placenta]].		'''Placental mesenchymal dysplasia''', abbreviated '''PMD''', is a very rare pathology of the [[placenta]].

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	*Stem villi = large villi with a fibrotic core and (fetal) arteries and veins.<ref name=pmid9260835>{{Cite journal \| last1 = Demir \| first1 = R. \| last2 = Kosanke \| first2 = G. \| last3 = Kohnen \| first3 = G. \| last4 = Kertschanska \| first4 = S. \| last5 = Kaufmann \| first5 = P. \| title = Classification of human placental stem villi: review of structural and functional aspects. \| journal = Microsc Res Tech \| volume = 38 \| issue = 1-2 \| pages = 29-41 \| month = \| year = \| doi = 10.1002/(SICI)1097-0029(19970701/15)38:1/229::AID-JEMT53.0.CO;2-P \| PMID = 9260835 }}</ref>		*Stem villi = large villi with a fibrotic core and (fetal) arteries and veins.<ref name=pmid9260835>{{Cite journal \| last1 = Demir \| first1 = R. \| last2 = Kosanke \| first2 = G. \| last3 = Kohnen \| first3 = G. \| last4 = Kertschanska \| first4 = S. \| last5 = Kaufmann \| first5 = P. \| title = Classification of human placental stem villi: review of structural and functional aspects. \| journal = Microsc Res Tech \| volume = 38 \| issue = 1-2 \| pages = 29-41 \| month = \| year = \| doi = 10.1002/(SICI)1097-0029(19970701/15)38:1/229::AID-JEMT53.0.CO;2-P \| PMID = 9260835 }}</ref>

	Image:		DDx:
			*[[Placental villous immaturity]].
			*[[Fetal thrombotic vasculopathy]].

			===Image===
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094260/figure/F5/ PMD (nih.gov)].<ref name=pmid21513565/>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094260/figure/F5/ PMD (nih.gov)].<ref name=pmid21513565/>

Michael: split out

2014-05-19T00:01:36Z

split out

← Older revision		Revision as of 00:01, 19 May 2014
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	~~#redirect~~ [[~~Placenta#Placental_mesenchymal_dysplasia~~]]		'''Placental mesenchymal dysplasia''', abbreviated '''PMD''', is a very rare pathology of the [[placenta]].

			==General==
			*Very rare ~ 70 reported cases.<ref name=pmid16753607>{{Cite journal \| last1 = Pham \| first1 = T. \| last2 = Steele \| first2 = J. \| last3 = Stayboldt \| first3 = C. \| last4 = Chan \| first4 = L. \| last5 = Benirschke \| first5 = K. \| title = Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. \| journal = Am J Clin Pathol \| volume = 126 \| issue = 1 \| pages = 67-78 \| month = Jul \| year = 2006 \| doi = 10.1309/RV45-HRD5-3YQ2-YFTP \| PMID = 16753607 }}</ref>
			*Etiology unknown.

			Associations:<ref name=pmid16753607/>
			*[[IUGR]] ~ 50% of cases.
			*Fetal demise ~ 40-45% of cases.
			*[[Beckwith-Wiedemann syndrome]].

			==Gross==
			Features:<ref name=pmid23266781>{{Cite journal \| last1 = Rohilla \| first1 = M. \| last2 = Siwatch \| first2 = S. \| last3 = Jain \| first3 = V. \| last4 = Nijhawan \| first4 = R. \| title = Placentomegaly and placental mesenchymal dysplasia. \| journal = BMJ Case Rep \| volume = 2012 \| issue = \| pages = \| month = \| year = 2012 \| doi = 10.1136/bcr-2012-007777 \| PMID = 23266781 }}</ref>
			*[[Placentomegaly]].
			*Grape-like vesicles.

			DDx - gross:
			*[[Partial hydatidiform mole]].

			Image:
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094260/figure/F3/ PMD (nih.gov)].<ref name=pmid21513565/>
			==Microscopic==
			Features:<ref name=pmid21513565>{{Cite journal \| last1 = Umazume \| first1 = T. \| last2 = Kataoka \| first2 = S. \| last3 = Kamamuta \| first3 = K. \| last4 = Tanuma \| first4 = F. \| last5 = Sumie \| first5 = A. \| last6 = Shirogane \| first6 = T. \| last7 = Kudou \| first7 = T. \| last8 = Ikeda \| first8 = H. \| title = Placental mesenchymal dysplasia, a case of intrauterine sudden death of fetus with rupture of cirsoid periumbilical chorionic vessels. \| journal = Diagn Pathol \| volume = 6 \| issue = \| pages = 38 \| month = \| year = 2011 \| doi = 10.1186/1746-1596-6-38 \| PMID = 21513565 }}</ref>
			*Stem villi with edema (hydropic changes) and few blood vessels.
			*Paucivascular (few blood vessels) or avascular (terminal) villi.

			Note:
			*Stem villi = large villi with a fibrotic core and (fetal) arteries and veins.<ref name=pmid9260835>{{Cite journal \| last1 = Demir \| first1 = R. \| last2 = Kosanke \| first2 = G. \| last3 = Kohnen \| first3 = G. \| last4 = Kertschanska \| first4 = S. \| last5 = Kaufmann \| first5 = P. \| title = Classification of human placental stem villi: review of structural and functional aspects. \| journal = Microsc Res Tech \| volume = 38 \| issue = 1-2 \| pages = 29-41 \| month = \| year = \| doi = 10.1002/(SICI)1097-0029(19970701/15)38:1/229::AID-JEMT53.0.CO;2-P \| PMID = 9260835 }}</ref>

			Image:
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094260/figure/F5/ PMD (nih.gov)].<ref name=pmid21513565/>

			==See also==
			*[[Placenta]].

			==References==
			{{Reflist\|2}}

			[[Category:Placenta]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: redirect

2013-02-02T03:00:39Z

redirect

New page

#redirect [[Placenta#Placental_mesenchymal_dysplasia]]

[[Category:Diagnosis]]