Placental alkaline phosphatase - Revision history

Michael at 19:06, 8 January 2017

2017-01-08T19:06:20Z

← Older revision		Revision as of 19:06, 8 January 2017
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	\| Pattern = membranous		\| Pattern = membranous
	\| Positive = [[germ cell neoplasia in situ]] (previously ITGCN), [[seminoma]], [[embryonal carcinoma]]		\| Positive = [[germ cell neoplasia in situ]] (previously ITGCN), [[seminoma]], [[embryonal carcinoma]]
	\| Negative =		\| Negative = normal testis, Sertoli cells only
	\| Other =		\| Other =
	}}		}}

2017-01-08T19:05:43Z

Negative

← Older revision		Revision as of 19:05, 8 January 2017
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	==Negative==		==Negative==
	*Normal [[testis]].<ref name=pmid9104938>{{Cite journal \| last1 = Hawkins \| first1 = E. \| last2 = Heifetz \| first2 = SA. \| last3 = Giller \| first3 = R. \| last4 = Cushing \| first4 = B. \| title = The prepubertal testis (prenatal and postnatal): its relationship to intratubular germ cell neoplasia: a combined Pediatric Oncology Group and Children's Cancer Study Group. \| journal = Hum Pathol \| volume = 28 \| issue = 4 \| pages = 404-10 \| month = Apr \| year = 1997 \| doi = \| PMID = 9104938 }}</ref>		*Normal [[testis]].<ref name=pmid9104938>{{Cite journal \| last1 = Hawkins \| first1 = E. \| last2 = Heifetz \| first2 = SA. \| last3 = Giller \| first3 = R. \| last4 = Cushing \| first4 = B. \| title = The prepubertal testis (prenatal and postnatal): its relationship to intratubular germ cell neoplasia: a combined Pediatric Oncology Group and Children's Cancer Study Group. \| journal = Hum Pathol \| volume = 28 \| issue = 4 \| pages = 404-10 \| month = Apr \| year = 1997 \| doi = \| PMID = 9104938 }}</ref>
			*Sertoli cells only.

	==Positive==		==Positive==

2017-01-08T19:05:32Z

Images

← Older revision		Revision as of 19:05, 8 January 2017
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	===Images===		===Images===
	<gallery>		<gallery>
	Image: ITGCN and Sertoli cells only - PLAP -- intermed mag.jpg \| [[Germ cell neoplasia in situ]] (GCNIS) & [[Sertoli cells only]] (SCO) - intermed. mag.		Image: ITGCN and Sertoli cells only - PLAP -- intermed mag.jpg \| [[Germ cell neoplasia in situ]] (GCNIS) & Sertoli cells only (SCO) - intermed. mag.
	Image: ITGCN and Sertoli cells only - PLAP -- high mag.jpg \| GCNIS & SCO - high mag.		Image: ITGCN and Sertoli cells only - PLAP -- high mag.jpg \| GCNIS & SCO - high mag.
	Image: ITGCN and Sertoli cells only - PLAP -- very high mag.jpg \| GCNIS & SCO - very high mag.		Image: ITGCN and Sertoli cells only - PLAP -- very high mag.jpg \| GCNIS & SCO - very high mag.

2017-01-08T19:05:00Z

Positive

← Older revision		Revision as of 19:05, 8 January 2017
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	*[[Seminoma]].		*[[Seminoma]].
	*[[Embryonal carcinoma]].		*[[Embryonal carcinoma]].

			===Images===
			<gallery>
			Image: ITGCN and Sertoli cells only - PLAP -- intermed mag.jpg \| [[Germ cell neoplasia in situ]] (GCNIS) & [[Sertoli cells only]] (SCO) - intermed. mag.
			Image: ITGCN and Sertoli cells only - PLAP -- high mag.jpg \| GCNIS & SCO - high mag.
			Image: ITGCN and Sertoli cells only - PLAP -- very high mag.jpg \| GCNIS & SCO - very high mag.
			</gallery>

	==See also==		==See also==

2017-01-08T19:03:05Z

+infobox

← Older revision		Revision as of 19:03, 8 January 2017
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			{{ Infobox immunostain
			\| Name = {{PAGENAME}}
			\| Image = ITGCN and Sertoli cells only - PLAP -- high mag.jpg
			\| Width =
			\| Caption = PLAP in [[germ cell neoplasia in situ]] - left of image. (WC)
			\| Abbrev = PLAP
			\| Synonyms =
			\| Similar = OCT4, OCT3/4
			\| Clones =
			\| Use = [[germ cell tumours]]
			\| Subspecial = [[genitourinary pathology]], [[gynecologic pathology]]
			\| Pattern = membranous
			\| Positive = [[germ cell neoplasia in situ]] (previously ITGCN), [[seminoma]], [[embryonal carcinoma]]
			\| Negative =
			\| Other =
			}}
	'''Placental alkaline phosphatase''', abbreviated '''PLAP''', is a common [[immunostain]] used for assessing suspected [[germ cell tumours]].		'''Placental alkaline phosphatase''', abbreviated '''PLAP''', is a common [[immunostain]] used for assessing suspected [[germ cell tumours]].

2016-03-16T00:11:34Z

← Older revision		Revision as of 00:11, 16 March 2016
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	==Positive==		==Positive==
	*[[~~Intratubular germ~~ cell neoplasia]].<ref name=pmid12598912>{{Cite journal \| last1 = Schreiber \| first1 = L. \| last2 = Lifschitz-Mercer \| first2 = B. \| last3 = Paz \| first3 = G. \| last4 = Yavetz \| first4 = H. \| last5 = Elliott \| first5 = DJ. \| last6 = Kula \| first6 = K. \| last7 = Slowikowska-Hilczer \| first7 = J. \| last8 = Maymon \| first8 = BB. \| title = Double immunolabeling by the RBM and the PLAP markers for identifying intratubular (in situ) germ cell neoplasia of the testis. \| journal = Int J Surg Pathol \| volume = 11 \| issue = 1 \| pages = 17-20 \| month = Jan \| year = 2003 \| doi = \| PMID = 12598912 }}</ref>		*[[Germ cell neoplasia in situ]] (intratubular germ cell neoplasia).<ref name=pmid12598912>{{Cite journal \| last1 = Schreiber \| first1 = L. \| last2 = Lifschitz-Mercer \| first2 = B. \| last3 = Paz \| first3 = G. \| last4 = Yavetz \| first4 = H. \| last5 = Elliott \| first5 = DJ. \| last6 = Kula \| first6 = K. \| last7 = Slowikowska-Hilczer \| first7 = J. \| last8 = Maymon \| first8 = BB. \| title = Double immunolabeling by the RBM and the PLAP markers for identifying intratubular (in situ) germ cell neoplasia of the testis. \| journal = Int J Surg Pathol \| volume = 11 \| issue = 1 \| pages = 17-20 \| month = Jan \| year = 2003 \| doi = \| PMID = 12598912 }}</ref>
	*[[Seminoma]].		*[[Seminoma]].
	*[[Embryonal carcinoma]].		*[[Embryonal carcinoma]].

2014-08-15T15:19:12Z

tweak

← Older revision		Revision as of 15:19, 15 August 2014
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	'''Placental alkaline phosphatase''', abbreviated '''PLAP''', is a common ~~marker~~ used for assessing suspected [[germ cell tumours]].		'''Placental alkaline phosphatase''', abbreviated '''PLAP''', is a common [[immunostain]] used for assessing suspected [[germ cell tumours]].

	It has largely been replaced by OCT4.		It has largely been replaced by OCT4.

2014-08-15T15:18:41Z

← Older revision		Revision as of 15:18, 15 August 2014
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	'''Placental alkaline phosphatase''', abbreviated '''PLAP''', is a common ~~marked~~ used for assessing suspected [[germ cell tumours]].		'''Placental alkaline phosphatase''', abbreviated '''PLAP''', is a common marker used for assessing suspected [[germ cell tumours]].

	It has largely been replaced by OCT4.		It has largely been replaced by OCT4.

2014-08-15T01:58:24Z

Positive

← Older revision		Revision as of 01:58, 15 August 2014
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	==Positive==		==Positive==
	*[[Intratubular germ cell neoplasia]].		*[[Intratubular germ cell neoplasia]].<ref name=pmid12598912>{{Cite journal \| last1 = Schreiber \| first1 = L. \| last2 = Lifschitz-Mercer \| first2 = B. \| last3 = Paz \| first3 = G. \| last4 = Yavetz \| first4 = H. \| last5 = Elliott \| first5 = DJ. \| last6 = Kula \| first6 = K. \| last7 = Slowikowska-Hilczer \| first7 = J. \| last8 = Maymon \| first8 = BB. \| title = Double immunolabeling by the RBM and the PLAP markers for identifying intratubular (in situ) germ cell neoplasia of the testis. \| journal = Int J Surg Pathol \| volume = 11 \| issue = 1 \| pages = 17-20 \| month = Jan \| year = 2003 \| doi = \| PMID = 12598912 }}</ref>
	*[[Seminoma]].		*[[Seminoma]].
	*[[Embryonal carcinoma]].		*[[Embryonal carcinoma]].

2014-08-15T01:56:23Z

Positive

← Older revision		Revision as of 01:56, 15 August 2014
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	==Positive==		==Positive==
	*[[Intratubular germ cell neoplasia]].		*[[Intratubular germ cell neoplasia]].
			*[[Seminoma]].
			*[[Embryonal carcinoma]].

	==See also==		==See also==