Pit1 - Revision history

Jensflorian: + ref

2018-01-26T09:05:47Z

+ ref

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	'''POU domain, class 1, transcription factor 1''' (growth hormone factor 1), also known as POU1F1, abbreviated '''Pit1''', is a c[[immunostain]] used endocrinology.		'''POU domain, class 1, transcription factor 1''' (growth hormone factor 1), also known as POU1F1, abbreviated '''Pit1''', is a [[immunostain]] used endocrinology.

	==General==		==General==
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	* Lactotroph adenoma.		* Lactotroph adenoma.
	* Thyreotropha adenoma.		* Thyreotropha adenoma.
			* Mammary gland.<ref>{{Cite journal \| last1 = Sendon-Lago \| first1 = J. \| last2 = Seoane \| first2 = S. \| last3 = Eiro \| first3 = N. \| last4 = Bermudez \| first4 = MA. \| last5 = Macia \| first5 = M. \| last6 = Garcia-Caballero \| first6 = T. \| last7 = Vizoso \| first7 = FJ. \| last8 = Perez-Fernandez \| first8 = R. \| title = Cancer progression by breast tumors with Pit-1-overexpression is blocked by inhibition of metalloproteinase (MMP)-13. \| journal = Breast Cancer Res \| volume = 16 \| issue = 6 \| pages = 505 \| month = Dec \| year = 2014 \| doi = 10.1186/s13058-014-0505-8 \| PMID = 25527274 }}</ref>


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	==Negative==		==Negative==
			* Corticotroph adenoma.
			* Gonadotroph adenoma.
			* Null cell adenoma.

	==See also==		==See also==

Jensflorian: /* Positive */ +ref

2018-01-26T09:01:23Z

Positive: +ref

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	==Positive==		==Positive==
			Pit-1 lineage pituitary tumors:<ref>{{Cite journal \| last1 = Lloyd \| first1 = RV. \| last2 = Osamura \| first2 = RY. \| title = Transcription factors in normal and neoplastic pituitary tissues. \| journal = Microsc Res Tech \| volume = 39 \| issue = 2 \| pages = 168-81 \| month = Oct \| year = 1997 \| doi = 10.1002/(SICI)1097-0029(19971015)39:2<168::AID-JEMT8>3.0.CO;2-H \| PMID = 9361268 }}</ref>

	* Somatotroph adenoma.		* Somatotroph adenoma.
	* Lactotroph adenoma.		* Lactotroph adenoma.

Jensflorian: created

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created

New page

{{ Infobox immunostain
| Name = {{PAGENAME}}
| Image =
| Width =
| Caption = Pit1+ve in prolactinoma.
| Abbrev = Pit1
| Synonyms =
| Similar =
| Clones =
| Use =
| Subspecial =
| Pattern = nuclear staining
| Positive = Somatotroph, lactotroph adenoma
| Negative =
| Other =
}}

'''POU domain, class 1, transcription factor 1''' (growth hormone factor 1), also known as POU1F1, abbreviated '''Pit1''', is a c[[immunostain]] used endocrinology.

==General==
*Nuclear stain.

==Positive==
* Somatotroph adenoma.
* Lactotroph adenoma.
* Thyreotropha adenoma.

===Occasionally positive===

==Negative==

==See also==
*[[Pituitary gland]].

Wikipedia page: [https://en.wikipedia.org/wiki/Pituitary-specific_positive_transcription_factor_1]

==References==
{{Reflist|1}}

[[Category:Immunohistochemistry|Neuropathology]]