Pheochromocytoma - Revision history

Michael at 15:11, 27 November 2024

2024-11-27T15:11:17Z

← Older revision		Revision as of 15:11, 27 November 2024
Line 18:		Line 18:
	\| Assdx =		\| Assdx =
	\| Syndromes = [[Multiple endocrine neoplasia]] 2A and 2B, [[von Hippel-Lindau syndrome]],[[Neurofibromatosis]] type 1, familial paraganglioma syndromes (several)		\| Syndromes = [[Multiple endocrine neoplasia]] 2A and 2B, [[von Hippel-Lindau syndrome]],[[Neurofibromatosis]] type 1, familial paraganglioma syndromes (several)
	\| Clinicalhx = hypertension (classic Hx), paroxysms of tachycardia~~, headache, anxiety, hypertension~~		\| Clinicalhx = hypertension (classic Hx), paroxysms of tachycardia
	\| Signs =		\| Signs = urine metanephrines elevated
	\| Symptoms =		\| Symptoms = headache, anxiety
	\| Prevalence = uncommon		\| Prevalence = uncommon
	\| Bloodwork =		\| Bloodwork =

Michael: /* General */

2022-11-01T16:53:20Z

General

← Older revision		Revision as of 16:53, 1 November 2022
Line 38:		Line 38:

	Memory device - the rule of 10s:<ref name=Ref_PCPBoD8_586>{{Ref PCPBoD8\|586}}</ref>		Memory device - the rule of 10s:<ref name=Ref_PCPBoD8_586>{{Ref PCPBoD8\|586}}</ref>
	*10% extra-adrenal (e.g. carotid body, ~~organ~~ of Zuckerkandl (neighourhood of aortic bifuration/IMA branch point)).		*10% extra-adrenal (e.g. carotid body, ''Organ of Zuckerkandl'' (neighourhood of aortic bifuration/IMA branch point)).
	*10% bilateral.		*10% bilateral.
	*10% malignant.		*10% malignant.

Michael at 22:29, 9 October 2021

2021-10-09T22:29:35Z

← Older revision		Revision as of 22:29, 9 October 2021
Line 162:		Line 162:

	==Sign out==		==Sign out==
	Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|~~vauthors~~=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists'' does ''not'' have a [[CAP protocols\|synoptic]] for these currently (September 2021).{{fact}}		Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|authors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists'' does ''not'' have a [[CAP protocols\|synoptic]] for these currently (September 2021).{{fact}}

	<pre>		<pre>

Michael: /* Sign out */ tweak

2021-09-21T18:52:16Z

Sign out: tweak

← Older revision		Revision as of 18:52, 21 September 2021
Line 162:		Line 162:

	==Sign out==		==Sign out==
	Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists'' does ''not'' have a synoptic for these currently (September 2021).{{fact}}		Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists'' does ''not'' have a [[CAP protocols\|synoptic]] for these currently (September 2021).{{fact}}

	<pre>		<pre>

Michael: /* Sign out */

2021-09-21T18:50:32Z

Sign out

← Older revision		Revision as of 18:50, 21 September 2021
Line 162:		Line 162:

	==Sign out==		==Sign out==
	Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists''' does ''not'' have a synoptic for these currently (September 2021).{{fact}}		Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists'' does ''not'' have a synoptic for these currently (September 2021).{{fact}}

	<pre>		<pre>

Michael: /* Sign out */

2021-09-21T18:50:19Z

Sign out

← Older revision		Revision as of 18:50, 21 September 2021
Line 162:		Line 162:

	==Sign out==		==Sign out==
	Mete ''et al.''. created a synoptic report for these cases that may be used.<ref pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists''' does ''not'' have a synoptic for these currently (September 2021).{{fact}}		Mete ''et al.''. created a synoptic report for these cases that may be used.<ref name=pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists''' does ''not'' have a synoptic for these currently (September 2021).{{fact}}

	<pre>		<pre>

Michael: /* Sign out */

2021-09-21T18:50:07Z

Sign out

← Older revision		Revision as of 18:50, 21 September 2021
Line 162:		Line 162:

	==Sign out==		==Sign out==
			Mete ''et al.''. created a synoptic report for these cases that may be used.<ref pmid24476517>{{cite journal \|vauthors=Mete O, Tischler AS, de Krijger R, McNicol AM, Eisenhofer G, Pacak K, Ezzat S, Asa SL \|title=Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas \|journal=Arch Pathol Lab Med \|volume=138 \|issue=2 \|pages=182–8 \|date=February 2014 \|pmid=24476517 \|pmc=3909881 \|doi=10.5858/arpa.2012-0551-OA \|url=}}</ref> The ''College of American Pathologists''' does ''not'' have a synoptic for these currently (September 2021).{{fact}}

	<pre>		<pre>
	Right Adrenal (Mass), Adrenalectomy:		Right Adrenal (Mass), Adrenalectomy:

Michael: /* Sign out */ more

2016-11-10T18:28:03Z

Sign out: more

← Older revision		Revision as of 18:28, 10 November 2016
Line 162:		Line 162:

	==Sign out==		==Sign out==
			<pre>
			Right Adrenal (Mass), Adrenalectomy:
			- Pheochromocytoma, margin clear.

			Comment:
			The tumour stains as follows:
			POSITIVE: synaptophysin, chromogranin A, S-100 (sustentacular cells).
			NEGATIVE: EMA, inhibin.
			Proliferation (Ki-67): <2% of tumour cells.

			The immunostaining pattern is consistent with a pheochromocytoma.
			</pre>


			===Block letters===
	<pre>		<pre>
	ADRENAL MASS, RIGHT, ADRENALECTOMY:		ADRENAL MASS, RIGHT, ADRENALECTOMY:

Michael at 14:24, 12 May 2016

2016-05-12T14:24:03Z

← Older revision		Revision as of 14:24, 12 May 2016
Line 152:		Line 152:
	*Inhibin -ve.		*Inhibin -ve.
	**Positive in ACC.		**Positive in ACC.
	*Calretinin -ve.		*[[Calretinin]] -ve.
	**Positive in ACC.		**Positive in ACC.

	A panel:		A panel:
	*S-100, chromogranin, ~~calretin~~, EMA, PAX8.		*S-100, chromogranin, calretinin, EMA, PAX8.

	==[[Electron microscopy]]==		==[[Electron microscopy]]==

Michael: touch

2015-04-14T15:16:58Z

touch

← Older revision		Revision as of 15:16, 14 April 2015
Line 1:		Line 1:
	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Pheochromocytoma high mag.jpg		\| Image = Pheochromocytoma high mag.jpg
	\| Width =		\| Width =
	\| Caption = Pheochromocytoma. [[H&E stain]].		\| Caption = Pheochromocytoma. [[H&E stain]].