Peptic duodenitis - Revision history

Michael at 18:44, 5 February 2024

2024-02-05T18:44:41Z

← Older revision		Revision as of 18:44, 5 February 2024
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	*[[Brunner's gland hyperplasia]].		*[[Brunner's gland hyperplasia]].
	*[[Gastric heterotopia of the duodenum]].		*[[Gastric heterotopia of the duodenum]].
			*[[Helicobacter duodenitis]].

	===Images===		===Images===

Michael: /* General */

2016-05-03T12:45:32Z

General

← Older revision		Revision as of 12:45, 3 May 2016
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	==General==		==General==
	*A somewhat controversial type of [[chronic duodenitis]].		*''Peptic duodenitis'' is a somewhat controversial type of [[chronic duodenitis]].
	*Considered to be a consequence of [[peptic ulcer disease]] ([[Helicobacter gastritis]]).		*Considered to be a consequence of [[peptic ulcer disease]] ([[Helicobacter gastritis]]).
	*One of the key components of the diagnosis is foveolar metaplasia and it is disputed that this is really due to Helicobacter.		*One of the key components of the diagnosis is foveolar metaplasia and it is disputed that this is really due to Helicobacter.

Michael at 12:45, 3 May 2016

2016-05-03T12:45:14Z

← Older revision		Revision as of 12:45, 3 May 2016
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	'''Peptic duodenitis''' is controversial type of [[chronic duodenitis]]. This article deals with that controversy and '''foveolar metaplasia of the duodenum'''.		'''Peptic duodenitis''' is controversial type of [[chronic duodenitis]].

			This article deals with that controversy and '''foveolar metaplasia of the duodenum'''.

	==General==		==General==

Michael: split out

2016-05-03T12:39:07Z

split out

← Older revision		Revision as of 12:39, 3 May 2016
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	~~#redirect~~ [[Duodenum~~#Peptic_duodenitis~~]]		'''Peptic duodenitis''' is controversial type of [[chronic duodenitis]]. This article deals with that controversy and '''foveolar metaplasia of the duodenum'''.

			==General==
			*A somewhat controversial type of [[chronic duodenitis]].
			*Considered to be a consequence of [[peptic ulcer disease]] ([[Helicobacter gastritis]]).
			*One of the key components of the diagnosis is foveolar metaplasia and it is disputed that this is really due to Helicobacter.
			**Genta ''et al.'' consider gastric foveolar metaplasia a congenital lesion.<ref name=pmid20656325>{{Cite journal \| last1 = Genta \| first1 = RM. \| last2 = Kinsey \| first2 = RS. \| last3 = Singhal \| first3 = A. \| last4 = Suterwala \| first4 = S. \| title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. \| journal = Hum Pathol \| volume = 41 \| issue = 11 \| pages = 1593-600 \| month = Nov \| year = 2010 \| doi = 10.1016/j.humpath.2010.04.010 \| PMID = 20656325 }}</ref>

			==Microscopic==
			Features:<ref name=Ref_GLP145>{{Ref GLP\|145}}</ref>
			*Gastric foveolar metaplasia - '''key feature'''.
			*[[Brunner's gland hyperplasia]].
			*+/-Inflammation - neutrophils.{{fact}}
			*Ulceration.{{fact}}

			DDx:
			*[[Chronic duodenitis]] not otherwise specified - no foveolar metaplasia, abundant plasma cells.
			*[[Acute duodenitis]].
			*[[Brunner's gland hyperplasia]].
			*[[Gastric heterotopia of the duodenum]].

			===Images===
			<gallery>
			Image:Duodenum_with_foveolar_metaplasia_-_low_mag.jpg \| Duodenum with foveolar metaplasia - low mag. (WC/Nephron)
			Image:Duodenum_with_foveolar_metaplasia_-_intermed_mag.jpg \| Duodenum with foveolar metaplasia - intermed. mag. (WC/Nephron)
			Image:Duodenum_with_foveolar_metaplasia_-_alt_-_very_high_mag.jpg \| Duodenum with foveolar metaplasia - very high mag. (WC/Nephron)
			</gallery>
			==Stains==
			Foveolar metaplasia:
			*[[PAS stain]] +ve.<ref name=Ref_GLP145>{{Ref GLP\|145}}</ref>
			*[[Mucicarmine stain]] +ve.

			==Sign out==
			===Foveolar metaplasia only===
			<pre>
			DUODENUM, BIOPSY:
			- SMALL BOWEL MUCOSA WITH FOCAL GASTRIC FOVEOLAR METAPLASIA.
			- BRUNNER'S GLANDS NOT IDENTIFIED.
			- VILLI AND INTRAEPITHELIAL LYMPHOCYTES WITHIN NORMAL LIMITS (NEGATIVE FOR CELIAC DISEASE).
			- NEGATIVE FOR ACUTE DUODENITIS.
			- NEGATIVE FOR DYSPLASIA.
			</pre>

			<pre>
			DUODENUM, BIOPSY:
			- SMALL BOWEL MUCOSA WITH FOCAL GASTRIC FOVEOLAR METAPLASIA.
			- BRUNNER'S GLANDS NOT IDENTIFIED.
			- NEGATIVE FOR ACUTE DUODENITIS.
			- NEGATIVE FOR DYSPLASIA.
			</pre>

			===Chronic duodenitis===
			<pre>
			Duodenum, Biopsy:
			- Small bowel mucosa with Brunner’s gland in the lamina propria and gastric foveolar metaplasia, consistent with chronic duodenitis.
			- NEGATIVE for acute duodenitis.
			- NEGATIVE for dysplasia and NEGATIVE for malignancy.
			</pre>

			<pre>
			DUODENUM, BIOPSY:
			- SMALL BOWEL MUCOSA WITH BRUNNER'S GLAND IN THE LAMINA PROPRIA AND
			GASTRIC FOVEOLAR METAPLASIA -- CONSISTENT WITH CHRONIC DUODENITIS.
			- NEGATIVE FOR ACUTE DUODENITIS.
			- NEGATIVE FOR MALIGNANCY.
			</pre>

			<pre>
			DUODENUM, BIOPSY:
			- SMALL BOWEL MUCOSA WITH PROMINENT BRUNNER'S GLANDS AND FOCAL GASTRIC
			FOVEOLAR METAPLASIA.
			- NEGATIVE FOR ACUTE INFLAMMATION.
			- NEGATIVE FOR DYSPLASIA.
			</pre>

			====Micro====
			The sections show small bowel mucosa and a small amount of submucosa. Brunner's glands are abundant and found focally in the lamina propria. Gastric foveolar-type epithelium is identified. Intraepithelial neutrophils are not identified.

			The epithelium matures appropriately. There is no increase in intraepithelial lymphocytes.

			==See also==
			*[[Chronic duodenitis]].
			*[[Gastric heterotopia of the duodenum]].

			==References==
			{{Reflist\|1}}

			[[Category:Duodenum]]
			[[Category:Diagnosis]]

Michael: Redirected page to Duodenum#Peptic duodenitis

2013-05-28T17:37:25Z

Redirected page to Duodenum#Peptic duodenitis

← Older revision		Revision as of 17:37, 28 May 2013
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	#redirect [[Duodenum#~~Chronic_duodenitis~~]]		#redirect [[Duodenum#Peptic_duodenitis]]

Michael at 16:09, 11 December 2012

2012-12-11T16:09:23Z

← Older revision		Revision as of 16:09, 11 December 2012
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	#redirect [[Duodenum#Chronic_duodenitis]]		#redirect [[Duodenum#Chronic_duodenitis]]

	~~[[Category:Diagnosis]]~~

Michael: Redirected page to Duodenum#Chronic duodenitis

2012-12-11T16:09:17Z

Redirected page to Duodenum#Chronic duodenitis

← Older revision		Revision as of 16:09, 11 December 2012
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	#redirect [[Duodenum#~~Peptic_duodenitis~~]]		#redirect [[Duodenum#Chronic_duodenitis]]

	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: redirect

2012-05-05T13:43:02Z

redirect

New page

#redirect [[Duodenum#Peptic_duodenitis]]

[[Category:Diagnosis]]