Pediatric gastrointestinal pathology - Revision history

Brigitte: /* Images */

2018-05-06T18:35:41Z

Images

← Older revision		Revision as of 18:35, 6 May 2018
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	====Images====		====Images====
	*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090423115718994 GCH (surgicalpathologyatlas.com)].

	==Biliary atresia==		==Biliary atresia==

2018-04-12T12:30:15Z

Microscopic

← Older revision		Revision as of 12:30, 12 April 2018
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	Images:		Images:
	*[http://en.wikipedia.org/wiki/File:Neonatal_necrotizing_enterocolitis,_gross_pathology_20G0021_lores.jpg NEC - gross (WP)].		*[http://en.wikipedia.org/wiki/File:Neonatal_necrotizing_enterocolitis,_gross_pathology_20G0021_lores.jpg NEC - gross (WP)].
	*[https://library.med.utah.edu/WebPath/PEDHTML/PED045.html].		*[https://library.med.utah.edu/WebPath/PEDHTML/PED045.html NEC - micro].

	==Autoimmune enteropathy==		==Autoimmune enteropathy==

2018-04-12T12:29:32Z

Necrotizing enterocolitis

← Older revision		Revision as of 12:29, 12 April 2018
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	Images:		Images:
	*[http://en.wikipedia.org/wiki/File:Neonatal_necrotizing_enterocolitis,_gross_pathology_20G0021_lores.jpg NEC - gross (WP)].		*[http://en.wikipedia.org/wiki/File:Neonatal_necrotizing_enterocolitis,_gross_pathology_20G0021_lores.jpg NEC - gross (WP)].
			*[https://library.med.utah.edu/WebPath/PEDHTML/PED045.html].

	==Autoimmune enteropathy==		==Autoimmune enteropathy==

2018-04-12T12:25:10Z

Microscopic

← Older revision		Revision as of 12:25, 12 April 2018
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	Images:		Images:
	*[http://en.wikipedia.org/wiki/File:Neonatal_necrotizing_enterocolitis,_gross_pathology_20G0021_lores.jpg NEC - gross (WP)].		*[http://en.wikipedia.org/wiki/File:Neonatal_necrotizing_enterocolitis,_gross_pathology_20G0021_lores.jpg NEC - gross (WP)].
	*[http://cueflash.com/cardimages/answers/thumbnails/7/4/7747308.jpg NEC - micro. (cueflash.com)].<ref>URL: [http://cueflash.com/decks/Pathology_Pediatrics http://cueflash.com/decks/Pathology_Pediatrics]. Accessed on: 11 January 2011.</ref>

	==Autoimmune enteropathy==		==Autoimmune enteropathy==

2017-08-20T01:30:18Z

Microscopic

← Older revision		Revision as of 01:30, 20 August 2017
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	*Ganglion cells missing in submucosal plexus and myenteric plexus.		*Ganglion cells missing in submucosal plexus and myenteric plexus.
	**Increasing ganglia proximally into transition zone		**Increasing ganglia proximally into transition zone
	*Hypertrophy of neural plexuses-		*Hypertrophy of neural plexuses.
	**Many nerve trunks > 40 μm		**Many nerve trunks > 40 μm
	*Abnormal submucosal blood vessels may be seen		*Abnormal submucosal blood vessels may be seen

2017-08-20T01:29:37Z

Microscopic

← Older revision		Revision as of 01:29, 20 August 2017
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	Features:		Features:
	*Ganglion cells missing in submucosal plexus and myenteric plexus.		*Ganglion cells missing in submucosal plexus and myenteric plexus.
			**Increasing ganglia proximally into transition zone
			*Hypertrophy of neural plexuses-
			**Many nerve trunks > 40 μm
			*Abnormal submucosal blood vessels may be seen
	*+/-Submucosal fibrosis.		*+/-Submucosal fibrosis.

2017-08-20T01:23:12Z

IHC

← Older revision		Revision as of 01:23, 20 August 2017
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	**Nerve fibres +ve control.		**Nerve fibres +ve control.

	Others:<ref ~~name~~=~~pmid1640323~~/>		Others<ref>{{Cite book \| last1 = Lin \| first1 = Fan \| last2 = Prichard \| first2 = Jeffrey \| title = Handbook of practical immunohistochemistry : frequently asked question \| date = \| publisher = \| location = \| isbn = 9781493915774 \| pages = }}</ref>
	*~~NSE~~ ~ ~~normal~~.		:
	*~~S100~~ ~ ~~normal~~.		*Calretinin ~ -ve, Usually negative in hypertrophied nerve fibers in Hirschsprung’s disease, superior to acetylcholinesterase.
			*NSE ~ -ve, Highlights ganglion cells to exclude Hirschsprung’s disease; specific but not very sensitive.

	==Meconium ileus==		==Meconium ileus==

2017-08-20T01:05:06Z

Colonic aganglionosis

← Older revision		Revision as of 01:05, 20 August 2017
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	*Short-segment (75-80%): Rectum, distal sigmoid		*Short-segment (75-80%): Rectum, distal sigmoid
	*Long-segment HD (10-20%): Beyond splenic flexure		*Long-segment HD (10-20%): Beyond splenic flexure
	*Total colonic aganglionosis (5-15%): Entire colon.		*Total colonic aganglionosis (5-15%): Entire colon.<ref name=pmid25395999>{{Cite web \| last = \| first = \| title = Diagnosis of Hirschsprung's disease with particular emphasis on histopathology. A systematic review of current literature \| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/ \| publisher = \| date = \| accessdate = 19 August 2017 }}</ref>

	*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/figure/F0001/ Classification of Hirschsprung's disease according to the aganglionic segment length (https://www.ncbi.nlm.nih.gov)]		**[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/figure/F0001/ Classification of Hirschsprung's disease according to the aganglionic segment length (https://www.ncbi.nlm.nih.gov)]

	Image:		Image:

2017-08-19T20:11:45Z

Colonic aganglionosis

← Older revision		Revision as of 20:11, 19 August 2017
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	*Total colonic aganglionosis (5-15%): Entire colon.		*Total colonic aganglionosis (5-15%): Entire colon.

			*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/figure/F0001/ Classification of Hirschsprung's disease according to the aganglionic segment length (https://www.ncbi.nlm.nih.gov)]
	**[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/figure/F0001/ Classification of Hirschsprung's disease according to the aganglionic segment length (https://www.ncbi.nlm.nih.gov)]

	Image:		Image:

2017-08-19T17:36:20Z

Colonic aganglionosis

← Older revision		Revision as of 17:36, 19 August 2017
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	*Short-segment (75-80%): Rectum, distal sigmoid		*Short-segment (75-80%): Rectum, distal sigmoid
	*Long-segment HD (10-20%): Beyond splenic flexure		*Long-segment HD (10-20%): Beyond splenic flexure
	*Total colonic aganglionosis (5-15%): Entire colon		*Total colonic aganglionosis (5-15%): Entire colon.


	**[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/figure/F0001/ Classification of Hirschsprung's disease according to the aganglionic segment length (https://www.ncbi.nlm.nih.gov)]		**[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223113/figure/F0001/ Classification of Hirschsprung's disease according to the aganglionic segment length (https://www.ncbi.nlm.nih.gov)]