Paneth cell - Revision history

Michael: /* Paneth cell metaplasia */

2016-12-27T16:06:06Z

Paneth cell metaplasia

← Older revision		Revision as of 16:06, 27 December 2016
Line 11:		Line 11:
	If PCM is present:		If PCM is present:
	*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.		*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.
	*PCM in the context of adenomas may be associated with a higher risk of colorectal neoplasia.<ref name=pmid23232853>{{Cite journal \| last1 = Pai \| first1 = RK. \| last2 = Rybicki \| first2 = LA. \| last3 = Goldblum \| first3 = JR. \| last4 = Shen \| first4 = B. \| last5 = Xiao \| first5 = SY. \| last6 = Liu \| first6 = X. \| title = Paneth cells in colonic adenomas: association with male sex and adenoma burden. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 1 \| pages = 98-103 \| month = Jan \| year = 2013 \| doi = 10.1097/PAS.0b013e318267b02e \| PMID = 23232853 }}</ref>		*PCM in the context of colorectal adenomas may be associated with a higher risk of colorectal neoplasia.<ref name=pmid23232853>{{Cite journal \| last1 = Pai \| first1 = RK. \| last2 = Rybicki \| first2 = LA. \| last3 = Goldblum \| first3 = JR. \| last4 = Shen \| first4 = B. \| last5 = Xiao \| first5 = SY. \| last6 = Liu \| first6 = X. \| title = Paneth cells in colonic adenomas: association with male sex and adenoma burden. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 1 \| pages = 98-103 \| month = Jan \| year = 2013 \| doi = 10.1097/PAS.0b013e318267b02e \| PMID = 23232853 }}</ref>

	==Microscopic==		==Microscopic==

Michael: /* Paneth cell metaplasia */

2016-12-27T16:05:36Z

Paneth cell metaplasia

← Older revision		Revision as of 16:05, 27 December 2016
Line 11:		Line 11:
	If PCM is present:		If PCM is present:
	*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.		*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.
			*PCM in the context of adenomas may be associated with a higher risk of colorectal neoplasia.<ref name=pmid23232853>{{Cite journal \| last1 = Pai \| first1 = RK. \| last2 = Rybicki \| first2 = LA. \| last3 = Goldblum \| first3 = JR. \| last4 = Shen \| first4 = B. \| last5 = Xiao \| first5 = SY. \| last6 = Liu \| first6 = X. \| title = Paneth cells in colonic adenomas: association with male sex and adenoma burden. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 1 \| pages = 98-103 \| month = Jan \| year = 2013 \| doi = 10.1097/PAS.0b013e318267b02e \| PMID = 23232853 }}</ref>

	==Microscopic==		==Microscopic==

Michael: /* See also */

2016-12-08T02:20:26Z

Michael at 16:46, 10 June 2014

2014-06-10T16:46:50Z

← Older revision		Revision as of 16:46, 10 June 2014
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	[[Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg \| thumb \| right \|Paneth cell metaplasia. [[H&E stain]].]]		[[Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg \| thumb \| right \|Paneth cell metaplasia and lamina propria [[eosinophil]]s. [[H&E stain]]. ]]
	The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.		The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.

Michael at 11:43, 20 January 2014

2014-01-20T11:43:16Z

← Older revision		Revision as of 11:43, 20 January 2014
Line 11:		Line 11:
	If PCM is present:		If PCM is present:
	*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.		*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.

	~~Note:~~
	*Some claim that (friendly right colonic) paneth cells and paneth cell metaplasia look quite different and can be distinguished.<ref name=pmid12655793>{{cite journal \|author=Rubio CA, Nesi G \|title=A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections \|journal=In Vivo \|volume=17 \|issue=1 \|pages=67–71 \|year=2003 \|pmid=12655793 \|doi= \|url=}}</ref>

	==Microscopic==		==Microscopic==
Line 32:		Line 29:
	Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg \| PCM - extremely high mag. (WC)		Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg \| PCM - extremely high mag. (WC)
	</gallery>		</gallery>

			==IHC==
			*Lysozyme +ve.<ref name=pmid12655793>{{cite journal \|author=Rubio CA, Nesi G \|title=A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections \|journal=In Vivo \|volume=17 \|issue=1 \|pages=67–71 \|year=2003 \|pmid=12655793 \|doi= \|url=}}</ref>

	==See also==		==See also==

Michael: +images

2014-01-19T03:16:43Z

+images

← Older revision		Revision as of 03:16, 19 January 2014
Line 24:		Line 24:
	*Intraepithelial [[eosinophil]]s.		*Intraepithelial [[eosinophil]]s.
	**Eosinophils have smaller (~1/2) more intensely red granules.		**Eosinophils have smaller (~1/2) more intensely red granules.

			===Images===
			<gallery>
			Image: Paneth cell metaplasia in the left colon -- intermed mag.jpg \| PCM - intermed. mag. (WC)
			Image: Paneth cell metaplasia in the left colon -- high mag.jpg \| PCM - high mag. (WC)
			Image: Paneth cell metaplasia in the left colon -- very high mag.jpg \| PCM - very high mag. (WC)
			Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg \| PCM - extremely high mag. (WC)
			</gallery>

	==See also==		==See also==

Michael: tweak

2014-01-19T03:14:51Z

tweak

← Older revision		Revision as of 03:14, 19 January 2014
Line 2:		Line 2:
	The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.		The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.

	'''Paneth cell metaplasia''' ~~redirect~~ to this article.		'''Paneth cell metaplasia''', abbreviated '''PCM''', redirects to this article.

	==General==		==General==
	*Paneth cells should ''not'' be in the left colon<ref name=pmid11851832>{{cite journal \|author=Tanaka M, Saito H, Kusumi T, ''et al'' \|title=Spatial distribution and histogenesis of colorectal Paneth cell metaplasia in idiopathic inflammatory bowel disease \|journal=J. Gastroenterol. Hepatol. \|volume=16 \|issue=12 \|pages=1353–9 \|year=2001 \|month=December \|pmid=11851832 \|doi= \|url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0815-9319&date=2001&volume=16&issue=12&spage=1353}}</ref> ~~- if~~ you see 'em ~~think~~ of [[inflammatory bowel disease]] and other long-standing injurious processes.		*Paneth cells should ''not'' be in the left colon.<ref name=pmid11851832>{{cite journal \|author=Tanaka M, Saito H, Kusumi T, ''et al'' \|title=Spatial distribution and histogenesis of colorectal Paneth cell metaplasia in idiopathic inflammatory bowel disease \|journal=J. Gastroenterol. Hepatol. \|volume=16 \|issue=12 \|pages=1353–9 \|year=2001 \|month=December \|pmid=11851832 \|doi= \|url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0815-9319&date=2001&volume=16&issue=12&spage=1353}}</ref>
			**If you see 'em there it is '''Paneth cell metaplasia'''.

			===Paneth cell metaplasia===
			If PCM is present:
			*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.

			Note:
	*Some claim that (friendly right colonic) paneth cells and paneth cell metaplasia look quite different and can be distinguished.<ref name=pmid12655793>{{cite journal \|author=Rubio CA, Nesi G \|title=A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections \|journal=In Vivo \|volume=17 \|issue=1 \|pages=67–71 \|year=2003 \|pmid=12655793 \|doi= \|url=}}</ref>		*Some claim that (friendly right colonic) paneth cells and paneth cell metaplasia look quite different and can be distinguished.<ref name=pmid12655793>{{cite journal \|author=Rubio CA, Nesi G \|title=A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections \|journal=In Vivo \|volume=17 \|issue=1 \|pages=67–71 \|year=2003 \|pmid=12655793 \|doi= \|url=}}</ref>

Michael at 01:03, 19 January 2014

2014-01-19T01:03:42Z

← Older revision		Revision as of 01:03, 19 January 2014
Line 5:		Line 5:

	==General==		==General==
	*Paneth cells should ''not'' be in the left colon<ref name=pmid11851832>{{cite journal \|author=Tanaka M, Saito H, Kusumi T, ''et al'' \|title=Spatial distribution and histogenesis of colorectal Paneth cell metaplasia in idiopathic inflammatory bowel disease \|journal=J. Gastroenterol. Hepatol. \|volume=16 \|issue=12 \|pages=1353–9 \|year=2001 \|month=December \|pmid=11851832 \|doi= \|url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0815-9319&date=2001&volume=16&issue=12&spage=1353}}</ref> - if you see 'em think of ~~IBD~~ and other long-standing injurious processes.		*Paneth cells should ''not'' be in the left colon<ref name=pmid11851832>{{cite journal \|author=Tanaka M, Saito H, Kusumi T, ''et al'' \|title=Spatial distribution and histogenesis of colorectal Paneth cell metaplasia in idiopathic inflammatory bowel disease \|journal=J. Gastroenterol. Hepatol. \|volume=16 \|issue=12 \|pages=1353–9 \|year=2001 \|month=December \|pmid=11851832 \|doi= \|url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0815-9319&date=2001&volume=16&issue=12&spage=1353}}</ref> - if you see 'em think of [[inflammatory bowel disease]] and other long-standing injurious processes.
	*Some claim that (friendly right colonic) paneth cells and paneth cell metaplasia look quite different and can be distinguished.<ref name=pmid12655793>{{cite journal \|author=Rubio CA, Nesi G \|title=A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections \|journal=In Vivo \|volume=17 \|issue=1 \|pages=67–71 \|year=2003 \|pmid=12655793 \|doi= \|url=}}</ref>		*Some claim that (friendly right colonic) paneth cells and paneth cell metaplasia look quite different and can be distinguished.<ref name=pmid12655793>{{cite journal \|author=Rubio CA, Nesi G \|title=A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections \|journal=In Vivo \|volume=17 \|issue=1 \|pages=67–71 \|year=2003 \|pmid=12655793 \|doi= \|url=}}</ref>

Michael at 01:03, 19 January 2014

2014-01-19T01:03:02Z

← Older revision		Revision as of 01:03, 19 January 2014
Line 1:		Line 1:
			[[Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg \| thumb \| right \|Paneth cell metaplasia. [[H&E stain]].]]
	The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.		The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.

Michael: /* Microscopic */

2014-01-19T00:49:17Z

Microscopic

← Older revision		Revision as of 00:49, 19 January 2014
Line 15:		Line 15:
	**Subnuclear eosinophilic granules.		**Subnuclear eosinophilic granules.
	*Intraepithelial [[eosinophil]]s.		*Intraepithelial [[eosinophil]]s.
			**Eosinophils have smaller (~1/2) more intensely red granules.

	==See also==		==See also==

← Older revision		Revision as of 02:20, 8 December 2016
Line 37:		Line 37:
	*[[Inflammatory bowel disease]].		*[[Inflammatory bowel disease]].
	*[[Colon]].		*[[Colon]].
			*[[Paneth cell-like change of the prostate gland]].

	==References==		==References==