Ovarian metastasis - Revision history

Michael: /* Generally */

2025-11-10T16:12:34Z

Generally

← Older revision		Revision as of 16:12, 10 November 2025
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	* [[Breast]].		* [[Breast]].
	* [[Gastrointestinal pathology\|Gastrointestinal (GI) tract]].		* [[Gastrointestinal pathology\|Gastrointestinal (GI) tract]].
	** Pseudomyxoma peritonei, usu. [[appendix\|appendiceal]] origin.		** [[Pseudomyxoma peritonei]], usu. [[appendix\|appendiceal]] origin.
	** Krukenberg tumour = [[signet ring cell]] cancer with mucin production of GI origin.		** Krukenberg tumour = [[signet ring cell]] cancer with mucin production of GI origin.

Michael: /* Gross */

2016-01-28T14:25:21Z

Gross

← Older revision		Revision as of 14:25, 28 January 2016
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	*Small unilateral tumour size.		*Small unilateral tumour size.
	**<10 cm suggests metastasis.		**<10 cm suggests metastasis.
	**>13 cm = ovarian primary.		**>13 cm suggests ovarian primary.

	==Microscopic==		==Microscopic==

Michael: /* Microscopic */

2016-01-28T14:24:44Z

Microscopic

← Older revision		Revision as of 14:24, 28 January 2016
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	Note:		Note:
	*‡ ''Primary [[signet ring cell carcinoma]] of the ovary'' is exists but is very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>		*‡ ''Primary [[signet ring cell carcinoma]] of the ovary'' exists but is very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>
	===Images===		===Images===
	====Breast carcinoma====		====Breast carcinoma====

Michael: /* Microscopic */

2016-01-28T06:02:09Z

Microscopic

← Older revision		Revision as of 06:02, 28 January 2016
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	Note:		Note:
	*‡ ''Primary [[signet ring cell carcinoma]] of the ovary'' is ~~reported~~ but very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>		*‡ ''Primary [[signet ring cell carcinoma]] of the ovary'' is exists but is very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>
	===Images===		===Images===
	====Breast carcinoma====		====Breast carcinoma====

Michael: /* Microscopic */

2016-01-28T06:01:43Z

Microscopic

← Older revision		Revision as of 06:01, 28 January 2016
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	Features:		Features:
	*Predominantly surface involvement and nodular at low power.		*Predominantly surface involvement and nodular at low power.
	*+/-[[Signet ring cell]]s (suggestive of GI or breast primary).		*+/-[[Signet ring cell]]s (suggestive of GI or breast primary). ‡
	*[[Lymphovascular invasion]].		*[[Lymphovascular invasion]].

	Note:		Note:
	*''Primary [[signet ring cell carcinoma]] of the ovary'' is reported but very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>		*‡ ''Primary [[signet ring cell carcinoma]] of the ovary'' is reported but very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>
	===Images===		===Images===
	====Breast carcinoma====		====Breast carcinoma====

Michael: /* Microscopic */

2016-01-28T06:00:54Z

Microscopic

← Older revision		Revision as of 06:00, 28 January 2016
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	*[[Lymphovascular invasion]].		*[[Lymphovascular invasion]].

			Note:
			*''Primary [[signet ring cell carcinoma]] of the ovary'' is reported but very rare.<ref name=pmid21611142>{{Cite journal \| last1 = El-Safadi \| first1 = S. \| last2 = Stahl \| first2 = U. \| last3 = Tinneberg \| first3 = HR. \| last4 = Hackethal \| first4 = A. \| last5 = Muenstedt \| first5 = K. \| title = Primary signet ring cell mucinous ovarian carcinoma: a case report and literature review. \| journal = Case Rep Oncol \| volume = 3 \| issue = 3 \| pages = 451-7 \| month = Sep \| year = 2010 \| doi = 10.1159/000323003 \| PMID = 21611142 }}</ref>
	===Images===		===Images===
	====Breast carcinoma====		====Breast carcinoma====

Michael at 05:55, 28 January 2016

2016-01-28T05:55:16Z

← Older revision		Revision as of 05:55, 28 January 2016
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	\| Image = Adenocarcinoma_of_the_breast_metastatic_to_the_ovary_-_low_mag.jpg		\| Image = Adenocarcinoma_of_the_breast_metastatic_to_the_ovary_-_low_mag.jpg
	\| Width =		\| Width =
	\| Caption = Ovary with a metastasis from breast carcinoma. [[H&E stain]].		\| Caption = Ovary with a metastasis from breast carcinoma (left of image). [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = predominantly surface involvement and nodular (especially at low power), +/-signet ring cells (suggestive of GI or breast primary), [[lymphovascular invasion]]		\| Micro = predominantly surface involvement and nodular (especially at low power), +/-signet ring cells (suggestive of GI or breast primary), [[lymphovascular invasion]]

Michael: /* Image */

2016-01-28T05:52:33Z

Image

← Older revision		Revision as of 05:52, 28 January 2016
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	*[[Lymphovascular invasion]].		*[[Lymphovascular invasion]].

	===~~Image~~===		===Images===
			====Breast carcinoma====
	<gallery>		<gallery>
	Image:Adenocarcinoma_of_the_breast_metastatic_to_the_ovary_-_low_mag.jpg \| Ovarian metastasis - low mag. (WC/~~Nephron~~)		Image:Adenocarcinoma_of_the_breast_metastatic_to_the_ovary_-_low_mag.jpg \| Ovarian metastasis (breast) - low mag. (WC)
			</gallery>
			====Urothelial carcinoma====
			<gallery>
			Image: Ovarian metastasis -- very low mag.jpg \| Ovary metastasis (UCC) - very low mag. (WC)
			Image: Ovarian metastasis -- low mag.jpg \| Ovary metastasis (UCC) - low mag. (WC)
			Image: Ovarian metastasis -- intermed mag.jpg \| Ovary metastasis (UCC) - intermed. mag. (WC)
			Image: Ovarian metastasis - alt -- intermed mag.jpg \| Ovary metastasis (UCC) - intermed. mag. (WC)
	</gallery>		</gallery>

Michael at 05:38, 28 January 2016

2016-01-28T05:38:27Z

← Older revision		Revision as of 05:38, 28 January 2016
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	==Generally==		==Generally==
	* Mostly Muellerian origin (uterus, [[fallopian tube]]) or pelvic [[peritoneum]].		* Mostly Muellerian origin ([[uterus]], [[fallopian tube]]) or pelvic [[peritoneum]].

	Common extramuellerian metastatic tumours:		Common extramuellerian metastatic tumours:

Michael at 05:35, 28 January 2016

2016-01-28T05:35:29Z

← Older revision		Revision as of 05:35, 28 January 2016
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	\| Caption = Ovary with a metastasis from breast carcinoma. [[H&E stain]].		\| Caption = Ovary with a metastasis from breast carcinoma. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro =		\| Micro = predominantly surface involvement and nodular (especially at low power), +/-signet ring cells (suggestive of GI or breast primary), [[lymphovascular invasion]]
	\| Subtypes =		\| Subtypes =
	\| LMDDx = ovarian primary tumours - esp. [[ovarian mucinous carcinoma]], [[serous carcinoma of the ovary]], [[endometrioid carcinoma of the ovary]]		\| LMDDx = ovarian primary tumours - esp. [[ovarian mucinous carcinoma]], [[serous carcinoma of the ovary]], [[endometrioid carcinoma of the ovary]]
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	\| Other =		\| Other =
	\| ClinDDx = ovarian primary		\| ClinDDx = ovarian primary
	\| Tx =		\| Tx = dependent on primary - often chemotherapy and radiation, occasionally de-bulking (surgery)
	}}		}}
	An '''ovarian metastasis''' (also '''ovary with metastatic disease''' and '''metastatic ovarian disease''') is [[cancer]] in the [[ovary]] that arose elsewhere and spread to the ovary.		An '''ovarian metastasis''' (also '''ovary with metastatic disease''' and '''metastatic ovarian disease''') is [[cancer]] in the [[ovary]] that arose elsewhere and spread to the ovary.