Ovarian fibroma - Revision history

Michael: /* Microscopic */

2015-11-29T16:04:28Z

Microscopic

← Older revision		Revision as of 16:04, 29 November 2015
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	DDx:		DDx:
	*[[Thecoma]] - lipid.		*[[Thecoma]] - lipid.
	*[[Leiomyoma]] - fascicular architecture, rare in the ovary.		*[[Leiomyoma]] - fascicular architecture, rare in the ovary.<ref name=pmid24761396>{{Cite journal \| last1 = Rajabi \| first1 = P. \| last2 = Hani \| first2 = M. \| last3 = Bagheri \| first3 = M. \| last4 = Mirzadeh \| first4 = F. \| title = Large ovarian leiomyoma in young woman. \| journal = Adv Biomed Res \| volume = 3 \| issue = \| pages = 88 \| month = \| year = 2014 \| doi = 10.4103/2277-9175.128001 \| PMID = 24761396 }}</ref>
	*[[Fibrosarcoma]] - nuclear atypia, classically herring bone pattern, very rare.		*[[Fibrosarcoma]] - nuclear atypia, classically herring bone pattern, very rare.
	*Metastatic [[metaplastic carcinoma]] - nuclear atypia, rare.		*Metastatic [[metaplastic carcinoma]] - nuclear atypia, rare.

Michael at 03:35, 31 October 2015

2015-10-31T03:35:04Z

← Older revision		Revision as of 03:35, 31 October 2015
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	\| Synonyms =		\| Synonyms =
	\| Micro = [[spindle cell]]s with a central nucleus and no nuclear atypia;		\| Micro = [[spindle cell]]s with a central nucleus and no nuclear atypia;
	patternless pattern (not fascicular, not herring bone), +/-calcification		patternless pattern (not fascicular, not [[herring bone]]), +/-calcification
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[thecoma]], [[leiomyoma]], [[fibrosarcoma]], metastatic [[metaplastic carcinoma]], [[endometriosis]] with fibrosis		\| LMDDx = [[thecoma]], [[leiomyoma]], [[fibrosarcoma]], metastatic [[metaplastic carcinoma]], [[endometriosis]] with fibrosis

Michael at 06:46, 22 October 2014

2014-10-22T06:46:11Z

← Older revision		Revision as of 06:46, 22 October 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Ovarian_fibroma_-_high_mag.jpg
			\| Width =
			\| Caption = Ovarian fibroma. [[H&E stain]].
			\| Synonyms =
			\| Micro = [[spindle cell]]s with a central nucleus and no nuclear atypia;
			patternless pattern (not fascicular, not herring bone), +/-calcification
			\| Subtypes =
			\| LMDDx = [[thecoma]], [[leiomyoma]], [[fibrosarcoma]], metastatic [[metaplastic carcinoma]], [[endometriosis]] with fibrosis
			\| Stains =
			\| IHC = inhibin -ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = solid white mass, usu. well-circumscribed
			\| Grossing =
			\| Site = [[ovary]] - see ''[[ovarian tumours]]''
			\| Assdx =
			\| Syndromes = [[Meigs syndrome]], [[nevoid basal cell carcinoma syndrome]] (esp. if calcified)
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx = other ovarian tumours - esp. solid ones
			\| Tx =
			}}
	'''Ovarian fibroma''' is a benign [[ovarian tumour]].		'''Ovarian fibroma''' is a benign [[ovarian tumour]].

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	==Gross==		==Gross==
	Features:		Features:
	*Solid white mass, ~~usu.~~ well-circumscribed.<ref name=Ref_AoGP398>{{Ref AoGP\|398}}</ref>		*Solid white mass, usually well-circumscribed.<ref name=Ref_AoGP398>{{Ref AoGP\|398}}</ref>

	Note:		Note:

Michael: fix ref

2014-10-22T06:35:43Z

fix ref

← Older revision		Revision as of 06:35, 22 October 2014
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	==Microscopic==		==Microscopic==
	Features:<ref>URL: [http://www.pathologyoutlines.com/ovarytumor.html#fibroma http://www.pathologyoutlines.com/ovarytumor.html#fibroma]. Accessed on: 7 May 2012.</ref><ref name=pmid16810055/>		Features:<ref>URL: [http://www.pathologyoutlines.com/ovarytumor.html#fibroma http://www.pathologyoutlines.com/ovarytumor.html#fibroma]. Accessed on: 7 May 2012.</ref><ref name=pmid16810055>{{Cite journal \| last1 = Roth \| first1 = LM. \| title = Recent advances in the pathology and classification of ovarian sex cord-stromal tumors. \| journal = Int J Gynecol Pathol \| volume = 25 \| issue = 3 \| pages = 199-215 \| month = Jul \| year = 2006 \| doi = 10.1097/01.pgp.0000192271.22289.e6 \| PMID = 16810055 }}</ref>
	*[[Spindle cell]]s with central nucleus and no nuclear atypia.		*[[Spindle cell]]s with central nucleus and no nuclear atypia.
	*Patternless pattern ([[AKA]] storiform pattern) - not fascicular, not herring bone.		*Patternless pattern ([[AKA]] storiform pattern) - not fascicular, not herring bone.

Michael: split out

2014-10-22T06:35:00Z

split out

← Older revision		Revision as of 06:35, 22 October 2014
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	#~~redirect~~ [[~~Ovarian_tumours~~#~~Ovarian_fibroma~~]]		'''Ovarian fibroma''' is a benign [[ovarian tumour]].

			==General==
			*May be a part of:
			*#[[Meigs syndrome]] (mnemonic ''FAR'': fibroma, [[ascites]], right pleural [[effusion]]).
			*#[[Nevoid basal cell carcinoma syndrome]] (NBCCS), AKA ''Gorlin syndrome''.<ref name=Ref_PBoD1103>{{Ref PBoD \|1103}}</ref>
			#In NBCCS classically - calcified and bilateral.<ref name=pmid6385289>{{Cite journal \| last1 = Tytle \| first1 = T. \| last2 = Rosin \| first2 = D. \| title = Bilateral calcified ovarian fibromas. \| journal = South Med J \| volume = 77 \| issue = 9 \| pages = 1178-80 \| month = Sep \| year = 1984 \| doi = \| PMID = 6385289 }}</ref>
			*Very rarely transform to [[adult fibrosarcoma\|fibrosarcoma]] <1%.<ref>URL: [http://brighamrad.harvard.edu/Cases/bwh/hcache/353/full.html http://brighamrad.harvard.edu/Cases/bwh/hcache/353/full.html]. Accessed on: 4 October 2011.</ref>

			==Gross==
			Features:
			*Solid white mass, usu. well-circumscribed.<ref name=Ref_AoGP398>{{Ref AoGP\|398}}</ref>

			Note:
			*Thecoma = yellow solid mass.<ref name=Ref_AoGP398>{{Ref AoGP\|398}}</ref>

			===Images===
			www:
			*[http://www.flickr.com/photos/78147607@N00/2871451742 Ovarian fibroma (flickr.com/euthman)].
			*[http://www.wikidoc.org/index.php/File:Ovarian_Fibroma.jpg Ovarian fibroma (wikidoc.org)].

			==Microscopic==
			Features:<ref>URL: [http://www.pathologyoutlines.com/ovarytumor.html#fibroma http://www.pathologyoutlines.com/ovarytumor.html#fibroma]. Accessed on: 7 May 2012.</ref><ref name=pmid16810055/>
			*[[Spindle cell]]s with central nucleus and no nuclear atypia.
			*Patternless pattern ([[AKA]] storiform pattern) - not fascicular, not herring bone.
			*Stainable lipid - minimal or none.<ref name=pmid16810055/>

			Notes:
			*May be cellular.
			*Mitotic activity minimal.<ref name=pmid20979607>{{Cite journal \| last1 = Huang \| first1 = L. \| last2 = Liao \| first2 = LM. \| last3 = Wang \| first3 = HY. \| last4 = Zheng \| first4 = M. \| title = Clinicopathologic characteristics and prognostic factors of ovarian fibrosarcoma: the results of a multi-center retrospective study. \| journal = BMC Cancer \| volume = 10 \| issue = \| pages = 585 \| month = \| year = 2010 \| doi = 10.1186/1471-2407-10-585 \| PMID = 20979607 }}</ref>

			DDx:
			*[[Thecoma]] - lipid.
			*[[Leiomyoma]] - fascicular architecture, rare in the ovary.
			*[[Fibrosarcoma]] - nuclear atypia, classically herring bone pattern, very rare.
			*Metastatic [[metaplastic carcinoma]] - nuclear atypia, rare.
			*[[Endometriosis]] with extensive fibrosis.

			===Images===
			<gallery>
			Image:Ovarian_fibroma_-_intermed_mag.jpg \| Ovarian fibroma - intermed mag. (WC)
			Image:Ovarian_fibroma_-_high_mag.jpg \| Ovarian fibroma - high mag. (WC)
			</gallery>

			==IHC==
			*Inhibin -ve (~75%).<ref name=pmid16810055/>

			==Sign out==
			<pre>
			OVARIAN MASS ("FIBROMA"), LEFT, EXCISION:
			- FIBROMA.
			- NEGATIVE FOR MALIGNANCY.
			</pre>

			===Micro===
			The sections show spindle cells in a patternless pattern. There is no appreciable nuclear atypia. No mitotic activity is apparent. No necrosis is identified. No calcifications are seen. A small amount of benign ovarian parenchyma is present at the edge of the lesion.

			==See also==
			*[[Ovarian tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Ovarian tumours]]

Michael: redirect

2011-10-18T03:12:48Z

redirect

← Older revision		Revision as of 03:12, 18 October 2011
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	#redirect [[Ovarian_tumours#Ovarian_fibroma]]		#redirect [[Ovarian_tumours#Ovarian_fibroma]]

			[[Category:Diagnosis]]

Michael: redirect

2011-08-10T20:31:42Z

redirect

New page

#redirect [[Ovarian_tumours#Ovarian_fibroma]]