Osteochondroma - Revision history

Michael: /* Microscopic */

2015-11-08T16:42:20Z

Microscopic

← Older revision		Revision as of 16:42, 8 November 2015
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	Notes:		Notes:
	*Benign cartilage - one chondrocyte per lacuna, small and round nucleus, no binucleation.		*Benign cartilage - one chondrocyte per lacuna, small and round nucleus, no binucleation.
			*[[Heterotopic ossification]] - no cartilage, away from joint.

	DDx:		DDx:

Michael at 16:36, 8 November 2015

2015-11-08T16:36:03Z

← Older revision		Revision as of 16:36, 8 November 2015
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	'''Osteochondroma''' is a common benign [[chondro-osseous tumour]].<ref name=pmid26226780>{{Cite journal \| last1 = Rogozhin \| first1 = DV. \| last2 = Bulycheva \| first2 = IV. \| last3 = Kushlinsky \| first3 = NE. \| last4 = Konovalov \| first4 = DM. \| last5 = Talalaev \| first5 = AG. \| last6 = Roshchin \| first6 = VY. \| last7 = Ektova \| first7 = AP. \| last8 = Kushnir \| first8 = BL. \| last9 = Kuzin \| first9 = AS. \| title = [Osteochondroma in children and adolescents]. \| journal = Arkh Patol \| volume = 77 \| issue = 3 \| pages = 37-40 \| month = \| year = \| doi = \| PMID = 26226780 }}</ref>		'''Osteochondroma''' is a common benign [[chondro-osseous tumour]].<ref name=pmid26226780>{{Cite journal \| last1 = Rogozhin \| first1 = DV. \| last2 = Bulycheva \| first2 = IV. \| last3 = Kushlinsky \| first3 = NE. \| last4 = Konovalov \| first4 = DM. \| last5 = Talalaev \| first5 = AG. \| last6 = Roshchin \| first6 = VY. \| last7 = Ektova \| first7 = AP. \| last8 = Kushnir \| first8 = BL. \| last9 = Kuzin \| first9 = AS. \| title = [Osteochondroma in children and adolescents]. \| journal = Arkh Patol \| volume = 77 \| issue = 3 \| pages = 37-40 \| month = \| year = \| doi = \| PMID = 26226780 }}</ref>

	''Exostosis''<ref name=pmid22654707>{{Cite journal \| last1 = Ohkuma \| first1 = R. \| last2 = McCarthy \| first2 = EF. \| last3 = Deune \| first3 = EG. \| title = Hereditary multiple exostoses in the hands and fingers: early presentation and early surgical treatment in family members. Case reports. \| journal = Hand (N Y) \| volume = 6 \| issue = 2 \| pages = 209-16 \| month = Jun \| year = 2011 \| doi = 10.1007/s11552-010-9307-3 \| PMID = 22654707 }}</ref> ~~Directs~~ here.		''Exostosis''<ref name=pmid22654707>{{Cite journal \| last1 = Ohkuma \| first1 = R. \| last2 = McCarthy \| first2 = EF. \| last3 = Deune \| first3 = EG. \| title = Hereditary multiple exostoses in the hands and fingers: early presentation and early surgical treatment in family members. Case reports. \| journal = Hand (N Y) \| volume = 6 \| issue = 2 \| pages = 209-16 \| month = Jun \| year = 2011 \| doi = 10.1007/s11552-010-9307-3 \| PMID = 22654707 }}</ref> redirects here.
	==General==		==General==
	*Benign.		*Benign.

Michael at 16:35, 8 November 2015

2015-11-08T16:35:48Z

← Older revision		Revision as of 16:35, 8 November 2015
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	'''Osteochondroma''' is a common benign [[chondro-osseous tumour]].<ref name=pmid26226780>{{Cite journal \| last1 = Rogozhin \| first1 = DV. \| last2 = Bulycheva \| first2 = IV. \| last3 = Kushlinsky \| first3 = NE. \| last4 = Konovalov \| first4 = DM. \| last5 = Talalaev \| first5 = AG. \| last6 = Roshchin \| first6 = VY. \| last7 = Ektova \| first7 = AP. \| last8 = Kushnir \| first8 = BL. \| last9 = Kuzin \| first9 = AS. \| title = [Osteochondroma in children and adolescents]. \| journal = Arkh Patol \| volume = 77 \| issue = 3 \| pages = 37-40 \| month = \| year = \| doi = \| PMID = 26226780 }}</ref>		'''Osteochondroma''' is a common benign [[chondro-osseous tumour]].<ref name=pmid26226780>{{Cite journal \| last1 = Rogozhin \| first1 = DV. \| last2 = Bulycheva \| first2 = IV. \| last3 = Kushlinsky \| first3 = NE. \| last4 = Konovalov \| first4 = DM. \| last5 = Talalaev \| first5 = AG. \| last6 = Roshchin \| first6 = VY. \| last7 = Ektova \| first7 = AP. \| last8 = Kushnir \| first8 = BL. \| last9 = Kuzin \| first9 = AS. \| title = [Osteochondroma in children and adolescents]. \| journal = Arkh Patol \| volume = 77 \| issue = 3 \| pages = 37-40 \| month = \| year = \| doi = \| PMID = 26226780 }}</ref>

			''Exostosis''<ref name=pmid22654707>{{Cite journal \| last1 = Ohkuma \| first1 = R. \| last2 = McCarthy \| first2 = EF. \| last3 = Deune \| first3 = EG. \| title = Hereditary multiple exostoses in the hands and fingers: early presentation and early surgical treatment in family members. Case reports. \| journal = Hand (N Y) \| volume = 6 \| issue = 2 \| pages = 209-16 \| month = Jun \| year = 2011 \| doi = 10.1007/s11552-010-9307-3 \| PMID = 22654707 }}</ref> Directs here.
	==General==		==General==
	*Benign.		*Benign.
	*Very common.		*Very common.<ref name=pmid26226780/>
	*Abnormal outgrowth of bone and cartilage - associated with growth plate.		*Abnormal outgrowth of bone and cartilage - associated with growth plate.
	*Usually present before age 20.<ref name=pmid12873205>{{Cite journal \| last1 = Parkin \| first1 = B. \| last2 = Bennett \| first2 = JC. \| last3 = Zaher \| first3 = A. \| title = Pathologic quiz case: an iliac mass in a 25-year-old woman. Osteochondroma. \| journal = Arch Pathol Lab Med \| volume = 127 \| issue = 8 \| pages = e355-6 \| month = Aug \| year = 2003 \| doi = 10.1043/1543-2165(2003)127e355:PQCAIM2.0.CO;2 \| PMID = 12873205 \| URL = http://www.archivesofpathology.org/doi/full/10.1043/1543-2165%282003%29127%3Ce355:PQCAIM%3E2.0.CO;2}}</ref>		*Usually present before age 20.<ref name=pmid12873205>{{Cite journal \| last1 = Parkin \| first1 = B. \| last2 = Bennett \| first2 = JC. \| last3 = Zaher \| first3 = A. \| title = Pathologic quiz case: an iliac mass in a 25-year-old woman. Osteochondroma. \| journal = Arch Pathol Lab Med \| volume = 127 \| issue = 8 \| pages = e355-6 \| month = Aug \| year = 2003 \| doi = 10.1043/1543-2165(2003)127e355:PQCAIM2.0.CO;2 \| PMID = 12873205 \| URL = http://www.archivesofpathology.org/doi/full/10.1043/1543-2165%282003%29127%3Ce355:PQCAIM%3E2.0.CO;2}}</ref>
			*May be multiple and hereditary.<ref name=pmid22654707/>

	==Gross==		==Gross==
	Features:		Features:

Michael: split out

2015-11-08T16:29:07Z

split out

← Older revision		Revision as of 16:29, 8 November 2015
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	~~#redirect~~ [[Chondro-~~osseous_tumours#Osteochondroma~~]]		'''Osteochondroma''' is a common benign [[chondro-osseous tumour]].<ref name=pmid26226780>{{Cite journal \| last1 = Rogozhin \| first1 = DV. \| last2 = Bulycheva \| first2 = IV. \| last3 = Kushlinsky \| first3 = NE. \| last4 = Konovalov \| first4 = DM. \| last5 = Talalaev \| first5 = AG. \| last6 = Roshchin \| first6 = VY. \| last7 = Ektova \| first7 = AP. \| last8 = Kushnir \| first8 = BL. \| last9 = Kuzin \| first9 = AS. \| title = [Osteochondroma in children and adolescents]. \| journal = Arkh Patol \| volume = 77 \| issue = 3 \| pages = 37-40 \| month = \| year = \| doi = \| PMID = 26226780 }}</ref>

			==General==
			*Benign.
			*Very common.
			*Abnormal outgrowth of bone and cartilage - associated with growth plate.
			*Usually present before age 20.<ref name=pmid12873205>{{Cite journal \| last1 = Parkin \| first1 = B. \| last2 = Bennett \| first2 = JC. \| last3 = Zaher \| first3 = A. \| title = Pathologic quiz case: an iliac mass in a 25-year-old woman. Osteochondroma. \| journal = Arch Pathol Lab Med \| volume = 127 \| issue = 8 \| pages = e355-6 \| month = Aug \| year = 2003 \| doi = 10.1043/1543-2165(2003)127e355:PQCAIM2.0.CO;2 \| PMID = 12873205 \| URL = http://www.archivesofpathology.org/doi/full/10.1043/1543-2165%282003%29127%3Ce355:PQCAIM%3E2.0.CO;2}}</ref>

			==Gross==
			Features:
			*Metasphyseal lesions.<ref name=medpath>URL: [http://www.medpath.info/MainContent/Skeletal/Bone_07.html http://www.medpath.info/MainContent/Skeletal/Bone_07.html]. Accessed on: 18 September 2012.</ref>
			**Often distal femur, proximal humerus or proximal tibia.<ref name=pmid12873205/>
			**Occasionally iliac mass.<ref name=pmid22217414>{{Cite journal \| last1 = Kokavec \| first1 = M. \| last2 = Gajdoš \| first2 = M. \| last3 = Džupa \| first3 = V. \| title = [Osteochondroma of the iliac crest: case report]. \| journal = Acta Chir Orthop Traumatol Cech \| volume = 78 \| issue = 6 \| pages = 583-5 \| month = \| year = 2011 \| doi = \| PMID = 22217414 }}
			</ref>
			*Mushroom-like shape - with broad or narrow base.

			Note:
			*Very unusual in craniofacial bones.<ref name=pmid12873205/>

			==Microscopic==
			Features:<ref name=pmid12873205/>
			*Bone - forms base of "mushroom".
			*Cartilage - layer usu. thinner in older individuals.
			**Lobular arrangement<ref name=upmc_case341>URL: [http://path.upmc.edu/cases/case341/dx.html http://path.upmc.edu/cases/case341/dx.html]. Accessed on: 19 September 2012.</ref> - clusters of 3-12 lacunae (separated by stroma).
			**May have mild atypia.
			**Nuclear enlargement - up to 5x normal.
			*[[Perichondrium]] - covers the cartilage.
			**Thin layer of cells - higher cellular density than cartilage.
			***Bland spindle cells in a fibrous (eosinophilic) stroma.

			Notes:
			*Benign cartilage - one chondrocyte per lacuna, small and round nucleus, no binucleation.

			DDx:
			*[[Chondrosarcoma]] - esp. in older individuals.

			===Images===
			<gallery>
			Image:Bone Osteochondroma LP CTR.jpg\|Bone - Osteochondroma - low power (SKB)
			Image:Bone Osteochondroma LP CTR (2).jpg\|Bone - Osteochondroma - low power (SKB)
			Image:Bone Osteochondroma HP CTR.jpg\|Bone - Osteochondroma - high power (SKB)
			Image:Bone Osteochondroma LP PA.JPG\|Bone - Osteochondroma - low power (SKB)
			Image:Bone Osteochondroma MP PA.JPG\|Bone - Osteochondroma - medium power (SKB)
			Image:Bone Osteochondroma MP2 PA.JPG\|Bone - Osteochondroma - medium power (SKB)
			</gallery>
			www:
			*[http://path.upmc.edu/cases/case341.html Super rare intracranial mesenchymal osteochondroma - several images (upmc.edu)].<ref name=upmc_case341/>

			==See also==
			*[[Chondro-osseous tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Chondro-osseous tumours]]

Michael: +cat.

2011-10-20T04:36:35Z

+cat.

← Older revision		Revision as of 04:36, 20 October 2011
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	#redirect [[Chondro-osseous_tumours#Osteochondroma]]		#redirect [[Chondro-osseous_tumours#Osteochondroma]]

			[[Category:Diagnosis]]

Michael: create redirect

2011-07-20T14:27:23Z

create redirect

New page

#redirect [[Chondro-osseous_tumours#Osteochondroma]]