Osteoblastoma - Revision history

Michael: /* Gross */

2016-02-23T21:02:36Z

Gross

← Older revision		Revision as of 21:02, 23 February 2016
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	**Vertebral column and sacrum - most common in one large series.<ref name=pmid8119712>{{Cite journal \| last1 = Lucas \| first1 = DR. \| last2 = Unni \| first2 = KK. \| last3 = McLeod \| first3 = RA. \| last4 = O'Connor \| first4 = MI. \| last5 = Sim \| first5 = FH. \| title = Osteoblastoma: clinicopathologic study of 306 cases. \| journal = Hum Pathol \| volume = 25 \| issue = 2 \| pages = 117-34 \| month = Feb \| year = 1994 \| doi = \| PMID = 8119712 }}</ref>		**Vertebral column and sacrum - most common in one large series.<ref name=pmid8119712>{{Cite journal \| last1 = Lucas \| first1 = DR. \| last2 = Unni \| first2 = KK. \| last3 = McLeod \| first3 = RA. \| last4 = O'Connor \| first4 = MI. \| last5 = Sim \| first5 = FH. \| title = Osteoblastoma: clinicopathologic study of 306 cases. \| journal = Hum Pathol \| volume = 25 \| issue = 2 \| pages = 117-34 \| month = Feb \| year = 1994 \| doi = \| PMID = 8119712 }}</ref>
	*Size important as per WHO definition:<ref name=pmid25224389>{{Cite journal \| last1 = Yalcinkaya \| first1 = U. \| last2 = Doganavsargil \| first2 = B. \| last3 = Sezak \| first3 = M. \| last4 = Kececi \| first4 = B. \| last5 = Argin \| first5 = M. \| last6 = Basdemir \| first6 = G. \| last7 = Oztop \| first7 = F. \| title = Clinical and morphological characteristics of osteoid osteoma and osteoblastoma: a retrospective single-center analysis of 204 patients. \| journal = Ann Diagn Pathol \| volume = 18 \| issue = 6 \| pages = 319-25 \| month = Dec \| year = 2014 \| doi = 10.1016/j.anndiagpath.2014.08.006 \| PMID = 25224389 }}</ref> ‡		*Size important as per WHO definition:<ref name=pmid25224389>{{Cite journal \| last1 = Yalcinkaya \| first1 = U. \| last2 = Doganavsargil \| first2 = B. \| last3 = Sezak \| first3 = M. \| last4 = Kececi \| first4 = B. \| last5 = Argin \| first5 = M. \| last6 = Basdemir \| first6 = G. \| last7 = Oztop \| first7 = F. \| title = Clinical and morphological characteristics of osteoid osteoma and osteoblastoma: a retrospective single-center analysis of 204 patients. \| journal = Ann Diagn Pathol \| volume = 18 \| issue = 6 \| pages = 319-25 \| month = Dec \| year = 2014 \| doi = 10.1016/j.anndiagpath.2014.08.006 \| PMID = 25224389 }}</ref> ‡
	*>= 2.0 cm: osteoblastoma.		**>= 2.0 cm: osteoblastoma.
	*<=1.0 cm: [[osteoid osteoma]].		**<=1.0 cm: [[osteoid osteoma]].
	*>1 cm and <2 cm: clinical and radiologic criteria should be considered.		**>1 cm and <2 cm: clinical and radiologic criteria should be considered.

	Note:		Note:

Michael at 21:02, 23 February 2016

2016-02-23T21:02:23Z

← Older revision		Revision as of 21:02, 23 February 2016
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	\| Prevalence =		\| Prevalence =
	\| Bloodwork =		\| Bloodwork =
	\| Rads = > 1.5 cm (~~smaller~~ lesions [[osteoid osteoma]]), often well-circumscribed, +/-cortical expansion, +/-cortical destruction		\| Rads = often >=2.0 cm (similar lesions 1-2 cm may be [[osteoid osteoma]]), often well-circumscribed, +/-cortical expansion, +/-cortical destruction
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = benign, may be locally destructive		\| Prognosis = benign, may be locally destructive
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	*Bone.		*Bone.
	**Vertebral column and sacrum - most common in one large series.<ref name=pmid8119712>{{Cite journal \| last1 = Lucas \| first1 = DR. \| last2 = Unni \| first2 = KK. \| last3 = McLeod \| first3 = RA. \| last4 = O'Connor \| first4 = MI. \| last5 = Sim \| first5 = FH. \| title = Osteoblastoma: clinicopathologic study of 306 cases. \| journal = Hum Pathol \| volume = 25 \| issue = 2 \| pages = 117-34 \| month = Feb \| year = 1994 \| doi = \| PMID = 8119712 }}</ref>		**Vertebral column and sacrum - most common in one large series.<ref name=pmid8119712>{{Cite journal \| last1 = Lucas \| first1 = DR. \| last2 = Unni \| first2 = KK. \| last3 = McLeod \| first3 = RA. \| last4 = O'Connor \| first4 = MI. \| last5 = Sim \| first5 = FH. \| title = Osteoblastoma: clinicopathologic study of 306 cases. \| journal = Hum Pathol \| volume = 25 \| issue = 2 \| pages = 117-34 \| month = Feb \| year = 1994 \| doi = \| PMID = 8119712 }}</ref>
	*~~'''Must'''~~ be ~~greater 1~~.5 cm ~~by definition~~.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4\|286}}</ref>		*Size important as per WHO definition:<ref name=pmid25224389>{{Cite journal \| last1 = Yalcinkaya \| first1 = U. \| last2 = Doganavsargil \| first2 = B. \| last3 = Sezak \| first3 = M. \| last4 = Kececi \| first4 = B. \| last5 = Argin \| first5 = M. \| last6 = Basdemir \| first6 = G. \| last7 = Oztop \| first7 = F. \| title = Clinical and morphological characteristics of osteoid osteoma and osteoblastoma: a retrospective single-center analysis of 204 patients. \| journal = Ann Diagn Pathol \| volume = 18 \| issue = 6 \| pages = 319-25 \| month = Dec \| year = 2014 \| doi = 10.1016/j.anndiagpath.2014.08.006 \| PMID = 25224389 }}</ref> ‡
			*>= 2.0 cm: osteoblastoma.
			*<=1.0 cm: [[osteoid osteoma]].
			*>1 cm and <2 cm: clinical and radiologic criteria should be considered.

			Note:
			*‡1.5 cm is a [[diagnostic size cutoff]] seen in older references.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4\|286}}</ref>

	===Radiology===		===Radiology===

Sarah: /* Images */

2014-12-27T07:28:00Z

Images

← Older revision		Revision as of 07:28, 27 December 2014
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	Image:Osteoblastoma_-_high_mag.jpg \| Osteoblastoma - high mag. (WC)		Image:Osteoblastoma_-_high_mag.jpg \| Osteoblastoma - high mag. (WC)
	Image:Osteoblastoma_-_low_mag.jpg \| Osteoblastoma - low mag. (WC)		Image:Osteoblastoma_-_low_mag.jpg \| Osteoblastoma - low mag. (WC)
			Image:Bone Osteoblastoma LP PA.JPG\|Osteoblastoma - low power. (SKB)
			Image:Bone Osteoblastoma MP3 PA.JPG\|Osteoblastoma - medium power. (SKB)
			Image:Bone Osteoblastoma MP2 PA.JPG\|Osteoblastoma - medium power. (SKB)
			Image:Bone Osteoblastoma OsteoblasticRimming PA.JPG\|Osteoblastoma - Higher power - Osteoblastic rimming. (SKB)
	</gallery>		</gallery>

Michael: fix sm errors

2013-08-27T14:23:21Z

fix sm errors

← Older revision		Revision as of 14:23, 27 August 2013
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	\| Width =		\| Width =
	\| Caption = Osteoblastoma. [[H&E stain]].		\| Caption = Osteoblastoma. [[H&E stain]].
	\| Micro = anastomosing bony [[trabeculae]] with variable mineralization, ~~osteoblast~~ rimming, no nuclear atypia of osteocytes		\| Micro = anastomosing bony [[trabeculae]] with variable mineralization, osteoblastic rimming, no nuclear atypia of osteocytes
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[osteoid osteoma]], [[osteosarcoma]]		\| LMDDx = [[osteoid osteoma]], [[osteosarcoma]]
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	Features:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4\|285}}</ref>		Features:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4\|285}}</ref>
	*Anastomosing bony [[trabeculae]] with:		*Anastomosing bony [[trabeculae]] with:
	**~~Osteoblasts~~ rimming.		**Osteoblastic rimming.
	***Cells line-up at edge of bone.		***Cells line-up at edge of bone.

Michael: /* General */ tweak

2013-08-26T21:42:05Z

General: tweak

← Older revision		Revision as of 21:42, 26 August 2013
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	*Uncommon.<ref name=pmid23362588>{{Cite journal \| last1 = Khan \| first1 = IS. \| last2 = Thakur \| first2 = JD. \| last3 = Chittiboina \| first3 = P. \| last4 = Nanda \| first4 = A. \| title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. \| journal = J La State Med Soc \| volume = 164 \| issue = 5 \| pages = 251-5 \| month = \| year = \| doi = \| PMID = 23362588 }}</ref>		*Uncommon.<ref name=pmid23362588>{{Cite journal \| last1 = Khan \| first1 = IS. \| last2 = Thakur \| first2 = JD. \| last3 = Chittiboina \| first3 = P. \| last4 = Nanda \| first4 = A. \| title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. \| journal = J La State Med Soc \| volume = 164 \| issue = 5 \| pages = 251-5 \| month = \| year = \| doi = \| PMID = 23362588 }}</ref>
	*Typically age 15-20 and male (male:female = ~2:1).<ref name=pmid20345366>{{Cite journal \| last1 = Villalobos \| first1 = CE. \| last2 = Rybak \| first2 = LD. \| last3 = Steiner \| first3 = GC. \| last4 = Wittig \| first4 = JC. \| title = Osteoblastoma of the sternum--case report and review of the literature. \| journal = Bull NYU Hosp Jt Dis \| volume = 68 \| issue = 1 \| pages = 55-9 \| month = \| year = 2010 \| doi = \| PMID = 20345366 }}</ref>		*Typically age 15-20 and male (male:female = ~2:1).<ref name=pmid20345366>{{Cite journal \| last1 = Villalobos \| first1 = CE. \| last2 = Rybak \| first2 = LD. \| last3 = Steiner \| first3 = GC. \| last4 = Wittig \| first4 = JC. \| title = Osteoblastoma of the sternum--case report and review of the literature. \| journal = Bull NYU Hosp Jt Dis \| volume = 68 \| issue = 1 \| pages = 55-9 \| month = \| year = 2010 \| doi = \| PMID = 20345366 }}</ref>
	**Very ~~wide~~ age range.<ref name=pmid8119712/>		**Very large age range.<ref name=pmid8119712/>
	*Treatment: resection.<ref name=pmid20345366/>		*Treatment: resection.<ref name=pmid20345366/>

Michael: /* General */

2013-08-26T21:41:43Z

General

← Older revision		Revision as of 21:41, 26 August 2013
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	*Uncommon.<ref name=pmid23362588>{{Cite journal \| last1 = Khan \| first1 = IS. \| last2 = Thakur \| first2 = JD. \| last3 = Chittiboina \| first3 = P. \| last4 = Nanda \| first4 = A. \| title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. \| journal = J La State Med Soc \| volume = 164 \| issue = 5 \| pages = 251-5 \| month = \| year = \| doi = \| PMID = 23362588 }}</ref>		*Uncommon.<ref name=pmid23362588>{{Cite journal \| last1 = Khan \| first1 = IS. \| last2 = Thakur \| first2 = JD. \| last3 = Chittiboina \| first3 = P. \| last4 = Nanda \| first4 = A. \| title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. \| journal = J La State Med Soc \| volume = 164 \| issue = 5 \| pages = 251-5 \| month = \| year = \| doi = \| PMID = 23362588 }}</ref>
	*Typically age 15-20 and male (male:female = ~2:1).<ref name=pmid20345366>{{Cite journal \| last1 = Villalobos \| first1 = CE. \| last2 = Rybak \| first2 = LD. \| last3 = Steiner \| first3 = GC. \| last4 = Wittig \| first4 = JC. \| title = Osteoblastoma of the sternum--case report and review of the literature. \| journal = Bull NYU Hosp Jt Dis \| volume = 68 \| issue = 1 \| pages = 55-9 \| month = \| year = 2010 \| doi = \| PMID = 20345366 }}</ref>		*Typically age 15-20 and male (male:female = ~2:1).<ref name=pmid20345366>{{Cite journal \| last1 = Villalobos \| first1 = CE. \| last2 = Rybak \| first2 = LD. \| last3 = Steiner \| first3 = GC. \| last4 = Wittig \| first4 = JC. \| title = Osteoblastoma of the sternum--case report and review of the literature. \| journal = Bull NYU Hosp Jt Dis \| volume = 68 \| issue = 1 \| pages = 55-9 \| month = \| year = 2010 \| doi = \| PMID = 20345366 }}</ref>
			**Very wide age range.<ref name=pmid8119712/>
	*Treatment: resection.<ref name=pmid20345366/>		*Treatment: resection.<ref name=pmid20345366/>

Michael: tweak

2013-08-26T21:39:44Z

tweak

← Older revision		Revision as of 21:39, 26 August 2013
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	\| ClinDDx = [[osteosarcoma]]		\| ClinDDx = [[osteosarcoma]]
	}}		}}
	'''Osteoblastoma''' is benign primary [[bone tumour]].		'''Osteoblastoma''' is benign primary [[bone tumour]]. It is grouped with the [[chondro-osseous tumours]].

	==General==		==General==

Michael: tewak

2013-08-26T21:38:12Z

tewak

← Older revision		Revision as of 21:38, 26 August 2013
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	\| Prevalence =		\| Prevalence =
	\| Bloodwork =		\| Bloodwork =
	\| Rads = > 1.5 cm (smaller lesions [[osteoid osteoma]]), often well-circumscribed, cortical expansion, +/-cortical destruction		\| Rads = > 1.5 cm (smaller lesions [[osteoid osteoma]]), often well-circumscribed, +/-cortical expansion, +/-cortical destruction
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = benign, may be locally destructive		\| Prognosis = benign, may be locally destructive

Michael: /* Gross */

2013-08-26T21:37:53Z

Gross

← Older revision		Revision as of 21:37, 26 August 2013
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	**Vertebral column and sacrum - most common in one large series.<ref name=pmid8119712>{{Cite journal \| last1 = Lucas \| first1 = DR. \| last2 = Unni \| first2 = KK. \| last3 = McLeod \| first3 = RA. \| last4 = O'Connor \| first4 = MI. \| last5 = Sim \| first5 = FH. \| title = Osteoblastoma: clinicopathologic study of 306 cases. \| journal = Hum Pathol \| volume = 25 \| issue = 2 \| pages = 117-34 \| month = Feb \| year = 1994 \| doi = \| PMID = 8119712 }}</ref>		**Vertebral column and sacrum - most common in one large series.<ref name=pmid8119712>{{Cite journal \| last1 = Lucas \| first1 = DR. \| last2 = Unni \| first2 = KK. \| last3 = McLeod \| first3 = RA. \| last4 = O'Connor \| first4 = MI. \| last5 = Sim \| first5 = FH. \| title = Osteoblastoma: clinicopathologic study of 306 cases. \| journal = Hum Pathol \| volume = 25 \| issue = 2 \| pages = 117-34 \| month = Feb \| year = 1994 \| doi = \| PMID = 8119712 }}</ref>
	*'''Must''' be greater 1.5 cm by definition.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4\|286}}</ref>		*'''Must''' be greater 1.5 cm by definition.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4\|286}}</ref>

			===Radiology===
			Features:
			*Often well-circumscribed, +/-cortical expansion, +/-cortical destruction.<ref name=pmid8119712/>

			Note:
			*May be described as malignant by radiology.<ref name=pmid8119712/>

	==Microscopic==		==Microscopic==

Michael: tweak some more

2013-08-26T21:36:01Z

tweak some more

← Older revision		Revision as of 21:36, 26 August 2013
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	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing =
	\| Site =		\| Site = [[bone]] - vertebral column typically, other bones
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx = usu. 15-20 years old, males > females		\| Clinicalhx = usu. 15-20 years old, males > females
	\| Signs =		\| Signs =
	\| Symptoms = ~~+/-~~pain		\| Symptoms = usu. pain
	\| Prevalence =		\| Prevalence =
	\| Bloodwork =		\| Bloodwork =
	\| Rads = > 1.5 cm (smaller lesions [[osteoid osteoma]])		\| Rads = > 1.5 cm (smaller lesions [[osteoid osteoma]]), often well-circumscribed, cortical expansion, +/-cortical destruction
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis =		\| Prognosis = benign, may be locally destructive
	\| Other =		\| Other =
	\| ClinDDx = [[osteosarcoma]]		\| ClinDDx = [[osteosarcoma]]
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	==General==		==General==
	*Benign bone tumour.		*Benign bone tumour - that can be locally destructive and occasionally recurs.<ref name=pmid8119712/>
	*Uncommon.<ref name=pmid23362588>{{Cite journal \| last1 = Khan \| first1 = IS. \| last2 = Thakur \| first2 = JD. \| last3 = Chittiboina \| first3 = P. \| last4 = Nanda \| first4 = A. \| title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. \| journal = J La State Med Soc \| volume = 164 \| issue = 5 \| pages = 251-5 \| month = \| year = \| doi = \| PMID = 23362588 }}</ref>		*Uncommon.<ref name=pmid23362588>{{Cite journal \| last1 = Khan \| first1 = IS. \| last2 = Thakur \| first2 = JD. \| last3 = Chittiboina \| first3 = P. \| last4 = Nanda \| first4 = A. \| title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. \| journal = J La State Med Soc \| volume = 164 \| issue = 5 \| pages = 251-5 \| month = \| year = \| doi = \| PMID = 23362588 }}</ref>
	*Typically age 15-20 and male (male:female = ~2:1).<ref name=pmid20345366>{{Cite journal \| last1 = Villalobos \| first1 = CE. \| last2 = Rybak \| first2 = LD. \| last3 = Steiner \| first3 = GC. \| last4 = Wittig \| first4 = JC. \| title = Osteoblastoma of the sternum--case report and review of the literature. \| journal = Bull NYU Hosp Jt Dis \| volume = 68 \| issue = 1 \| pages = 55-9 \| month = \| year = 2010 \| doi = \| PMID = 20345366 }}</ref>		*Typically age 15-20 and male (male:female = ~2:1).<ref name=pmid20345366>{{Cite journal \| last1 = Villalobos \| first1 = CE. \| last2 = Rybak \| first2 = LD. \| last3 = Steiner \| first3 = GC. \| last4 = Wittig \| first4 = JC. \| title = Osteoblastoma of the sternum--case report and review of the literature. \| journal = Bull NYU Hosp Jt Dis \| volume = 68 \| issue = 1 \| pages = 55-9 \| month = \| year = 2010 \| doi = \| PMID = 20345366 }}</ref>
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	Notes:		Notes:
	*Histomorphologically near identical/indistinguishable from ''[[osteoid osteoma]]''.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4\|286}}</ref>		*Histomorphologically near identical/indistinguishable from ''[[osteoid osteoma]]''.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4\|286}}</ref>

			DDx:
			*[[Osteosarcoma]].<ref name=pmid8119712/>

	===Images===		===Images===

← Older revision		Revision as of 07:28, 27 December 2014
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	Image:Osteoblastoma_-_high_mag.jpg \| Osteoblastoma - high mag. (WC)		Image:Osteoblastoma_-_high_mag.jpg \| Osteoblastoma - high mag. (WC)
	Image:Osteoblastoma_-_low_mag.jpg \| Osteoblastoma - low mag. (WC)		Image:Osteoblastoma_-_low_mag.jpg \| Osteoblastoma - low mag. (WC)
			Image:Bone Osteoblastoma LP PA.JPG\|Osteoblastoma - low power. (SKB)
			Image:Bone Osteoblastoma MP3 PA.JPG\|Osteoblastoma - medium power. (SKB)
			Image:Bone Osteoblastoma MP2 PA.JPG\|Osteoblastoma - medium power. (SKB)
			Image:Bone Osteoblastoma OsteoblasticRimming PA.JPG\|Osteoblastoma - Higher power - Osteoblastic rimming. (SKB)
	</gallery>		</gallery>