Non-specific interstitial pneumonia - Revision history

Michael: /* Microscopic */ +images

2015-03-17T18:53:17Z

Microscopic: +images

← Older revision		Revision as of 18:53, 17 March 2015
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	DDx:		DDx:
	*[[Collagen vascular disease]].		*[[Collagen vascular disease]].
	*Drug reaction.		*[[Drug reaction]].
	*[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis).		*[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis).
	*[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation.		*[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation.
	*[[Organizing pneumonia]].		*[[Organizing pneumonia]].

			===Images===
			<gallery>
			Image: Non-specfic_interstitial_pneumonia_(NSIP),_cellular_variant.jpg \| NSIP - cellular. (WC/Rosen)
			Image: Non-specfic_interstitial_pneumonia_(NSIP),_cellular_variant_2.jpg \| NSIP - cellular. (WC/Rosen)
			Image: Non-specfic interstitial pneumonia (NSIP), fibrosing variant.jpg \| NSIP - fibrosing. (WC/Rosen)
			Image: Non-specfic interstitial pneumonia (NSIP), fibrosing variant_2.jpg \| NSIP - fibrosing. (WC/Rosen)
			</gallery>

	==See also==		==See also==

Michael: fix

2015-03-17T18:50:18Z

fix

← Older revision		Revision as of 18:50, 17 March 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Non-~~specfic interstitial pneumonia~~ (NSIP), ~~fibrosing variant 2~~.jpg		\| Image = Non-specfic_interstitial_pneumonia_(NSIP),_cellular_variant.jpg
	\| Width =		\| Width =
	\| Caption = NSIP. [[H&E stain]].		\| Caption = NSIP. [[H&E stain]].

Michael at 18:49, 17 March 2015

2015-03-17T18:49:25Z

← Older revision		Revision as of 18:49, 17 March 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Non-specfic interstitial pneumonia (NSIP), fibrosing variant 2.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = NSIP. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]]		\| Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]]

Michael: /* General */

2014-07-03T14:51:45Z

General

← Older revision		Revision as of 14:51, 3 July 2014
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	Clinical features (typical) of the idiopathic form:<ref name=pmid20178304>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>		Clinical features (typical) of the idiopathic form:<ref name=pmid20178304>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>
	*Middle-aged, never-smoker women.		*Middle-aged, never-smoker women.
	*Dyspnea.		*[[Dyspnea]].
	*Cough.		*Cough.
	*Ground glass on HRCT.		*Ground glass on HRCT.

Michael: /* General */

2014-05-31T04:12:25Z

General

← Older revision		Revision as of 04:12, 31 May 2014
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	*If no underlying cause is present it is known as ''idiopathic NSIP''.		*If no underlying cause is present it is known as ''idiopathic NSIP''.

	Clinical features, typical - idiopathic form:<ref name=pmid20178304>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>		Clinical features (typical) of the idiopathic form:<ref name=pmid20178304>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>
	*Middle-aged, never-smoker women.		*Middle-aged, never-smoker women.
	*Dyspnea.		*Dyspnea.

Michael at 04:12, 31 May 2014

2014-05-31T04:12:07Z

← Older revision		Revision as of 04:12, 31 May 2014
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	\| Synonyms =		\| Synonyms =
	\| Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]]		\| Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]]
	\| Subtypes =		\| Subtypes = idiopathic NSIP, NSIP due to an underlying cause
	\| LMDDx = [[organizing pneumonia]], [[collagen vascular disease]], drug reaction, [[hypersensitivity pneumonitis]], [[lymphocytic interstitial pneumonia]]		\| LMDDx = [[organizing pneumonia]], [[collagen vascular disease]], drug reaction, [[hypersensitivity pneumonitis]], [[lymphocytic interstitial pneumonia]]
	\| Stains =		\| Stains =

Michael at 04:08, 31 May 2014

2014-05-31T04:08:37Z

← Older revision		Revision as of 04:08, 31 May 2014
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	\| Caption =		\| Caption =
	\| Synonyms =		\| Synonyms =
	\| Micro =		\| Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]]
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx = [[organizing pneumonia]], [[collagen vascular disease]], drug reaction, [[hypersensitivity pneumonitis]], [[lymphocytic interstitial pneumonia]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	\| Prevalence = uncommon		\| Prevalence = uncommon
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads = lower lung zone fibrosis, patchy ground glass, no honeycombing
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = good		\| Prognosis = good
	\| Other =		\| Other =
	\| ClinDDx =		\| ClinDDx =
	\| Tx =		\| Tx = corticosteroids (?)
	}}		}}
	'''Non-specific interstitial pneumonia''', abbreviated '''NSIP''', is an uncommon type of [[diffuse lung disease]].		'''Non-specific interstitial pneumonia''', abbreviated '''NSIP''', is an uncommon type of [[diffuse lung disease]].
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	DDx:		DDx:
	*Collagen vascular disease.		*[[Collagen vascular disease]].
	*Drug reaction.		*Drug reaction.
	*[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis).		*[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis).
	*[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation.		*[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation.
			*[[Organizing pneumonia]].

	==See also==		==See also==

Michael at 04:04, 31 May 2014

2014-05-31T04:04:55Z

← Older revision		Revision as of 04:04, 31 May 2014
Line 1:		Line 1:
			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[lung]] - see ''[[diffuse lung diseases]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = cough
			\| Symptoms = dyspnea
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = good
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Non-specific interstitial pneumonia''', abbreviated '''NSIP''', is an uncommon type of [[diffuse lung disease]].		'''Non-specific interstitial pneumonia''', abbreviated '''NSIP''', is an uncommon type of [[diffuse lung disease]].

Line 11:		Line 42:

	Note:		Note:
	*If no underlying cause is present it is known as ''idiopathic NSIP''.<ref>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>		*If no underlying cause is present it is known as ''idiopathic NSIP''.

			Clinical features, typical - idiopathic form:<ref name=pmid20178304>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>
			*Middle-aged, never-smoker women.
			*Dyspnea.
			*Cough.
			*Ground glass on HRCT.
			*Very good prognosis.

	==Gross/Radiology==		==Gross/Radiology==

Michael at 04:00, 31 May 2014

2014-05-31T04:00:39Z

← Older revision		Revision as of 04:00, 31 May 2014
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	*[[Connective tissue disease]].<ref name=pmid21437858>{{cite journal \|author=Hauber HP, Bittmann I, Kirsten D \|title=[Non-specific interstitial pneumonia (NSIP)] \|language=German \|journal=Pneumologie \|volume=65 \|issue=8 \|pages=477–83 \|year=2011 \|month=August \|pmid=21437858 \|doi=10.1055/s-0030-1256284 \|url=}}</ref>		*[[Connective tissue disease]].<ref name=pmid21437858>{{cite journal \|author=Hauber HP, Bittmann I, Kirsten D \|title=[Non-specific interstitial pneumonia (NSIP)] \|language=German \|journal=Pneumologie \|volume=65 \|issue=8 \|pages=477–83 \|year=2011 \|month=August \|pmid=21437858 \|doi=10.1055/s-0030-1256284 \|url=}}</ref>
	*[[Rheumatoid arthritis]].		*[[Rheumatoid arthritis]].

			Note:
			*If no underlying cause is present it is known as ''idiopathic NSIP''.<ref>{{cite journal \|author=Romagnoli M, Poletti V \|title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] \|language=Italian \|journal=Recenti Prog Med \|volume=100 \|issue=12 \|pages=531–4 \|year=2009 \|month=December \|pmid=20178304 \|doi= \|url=}}</ref>

	==Gross/Radiology==		==Gross/Radiology==

Michael: /* General */

2014-05-31T03:57:59Z

General

← Older revision		Revision as of 03:57, 31 May 2014
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	==General==		==General==
	*Better prognosis than [[UIP]].		*Better prognosis than [[UIP]].
	*Some radiologists and pathologists don't believe in this entity.		*May respond to corticosteroids.<ref name=pmid22690098>{{cite journal \|author=Lee JY, Jin SM, Lee BJ, ''et al.'' \|title=Treatment response and long term follow-up results of nonspecific interstitial pneumonia \|journal=J. Korean Med. Sci. \|volume=27 \|issue=6 \|pages=661–7 \|year=2012 \|month=June \|pmid=22690098 \|pmc=3369453 \|doi=10.3346/jkms.2012.27.6.661 \|url=}}</ref>
			*Some radiologists and pathologists don't believe in this entity.{{fact}}

	Associations:<ref name=Ref_WMSP92>{{Ref WMSP\|92}}</ref>		Associations:<ref name=Ref_WMSP92>{{Ref WMSP\|92}}</ref>