Non-malignant skin disease - Revision history

Michael: rm broken

2024-04-23T17:59:47Z

rm broken

← Older revision		Revision as of 17:59, 23 April 2024
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	Notes:		Notes:
	*It differs from [[verruca vulgaris]]... (1) orthokeratosis, (2) flat surface and base.		*It differs from [[verruca vulgaris]]... (1) orthokeratosis, (2) flat surface and base.

	~~====Images====~~
	~~www:~~
	*[http://www.fujita-hu.ac.jp/~tsutsumi/case/case180.htm Verruca plana - several images (fujita-hu.ac.jp)].
	*[http://www.dermatopathonline.com/verruca%20plana2.html Verruca plana - several good images (dermatopathonline.com)].

	=Less common=		=Less common=

Michael: /* Clear cell acanthoma */

2017-06-02T16:53:13Z

Clear cell acanthoma

← Older revision		Revision as of 16:53, 2 June 2017
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	==Clear cell acanthoma==		==Clear cell acanthoma==
	~~===General===~~		{{Main\|Clear cell acanthoma}}
	*Benign.
	*Elderly.
	*Classically on the leg.<ref name=pmid18583817>{{~~Cite journal~~ \| ~~last1 = Akin \| first1 = FY. \| last2 = Ertam \| first2 = I. \| last3 = Ceylan \| first3 = C. \| last4 = Kazandi \| first4 = A. \| last5 = Ozdemir \| first5 = F. \| title =~~ Clear cell acanthoma: new observations on dermatoscopy. \| journal = Indian J Dermatol Venereol Leprol \| volume = 74 \| issue = 3 \| pages = 285-7 \| month = \| year = \| doi = \| PMID = 18583817 \| URL = http://www.ijdvl.com/text.asp?2008/74/3/285/41396 }}</ref>
	*Rare.
	*Clinically not distinct.
	**Suspected clinically in only ~3% of cases.<ref name=pmid20931670>{{Cite journal \| last1 = Morrison \| first1 = LK. \| last2 = Duffey \| first2 = M. \| last3 = Janik \| first3 = M. \| last4 = Shamma \| first4 = HN. \| title = Clear cell acanthoma: a rare clinical diagnosis prior to biopsy. \| journal = Int J Dermatol \| volume = 49 \| issue = 9 \| pages = 1008-11 \| month = Sep \| year = 2010 \| doi = \| PMID = 20931670 }}~~</ref>~~

	~~===Microscopic===~~
	~~Features:<ref>URL: [http://www.drmihm.com/cases/case.cfm?CaseID=45 http://www.drmihm.com/cases/case.cfm?CaseID=45]. Accessed on: 7 February 2012.</ref>~~
	*Psoriasiform pattern - epidermal thickening ([[acanthosis]]).
	*Keratinocytes:
	**Pale or light pink cytoplasm (when compared to surrounding non-lesional keratinocytes).
	**Separated from one another (spongiosis).
	*+/-Stratum corneum [[neutrophil]]s.

	~~DDx:~~
	*[[Psoriasis vulgaris]].

	~~Images:~~
	*[http://www.drmihm.com/cases/casefigure.cfm?figID=906&CaseID=45 CCA (drmihm.com)].
	*[http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-327718365 CCA - low mag. (dermatlas.com)].
	*[http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=546460717 CCA - high mag. (dermatlas.com)].

	==Chondrodermatitis nodularis chronica helicis==		==Chondrodermatitis nodularis chronica helicis==

Michael: touch

2015-06-18T21:43:56Z

touch

← Older revision		Revision as of 21:43, 18 June 2015
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	'''Non-malignant skin disease''' is relatively common. The pathology may or may not be specific. Some diseases require clinical information to diagnose.		'''Non-malignant skin disease''' is relatively common. The pathology may or may not be specific. Some diseases require clinical information to diagnose.

	An introduction to dermatopathology is in the ''[[dermatopathology]]'' article. [[Nevi]] (moles) and other melanocytic lesions are dealt with in the article ''[[melanocytic lesions]]''. Inflammatory skin conditions are dealt with in ''[[inflammatory skin disorders]]''.		An introduction to dermatopathology is in the ''[[dermatopathology]]'' article. [[Nevi]] (moles) and other melanocytic lesions are dealt with in the article ''[[melanocytic lesions]]''. Inflammatory skin conditions are dealt with in ''[[inflammatory skin disorders]]''.

Michael: /* Dermatomycosis */

2014-09-24T06:49:38Z

Dermatomycosis

← Older revision		Revision as of 06:49, 24 September 2014
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	*[[Exocytosis]] - blood cell infiltrate the epidermis.		*[[Exocytosis]] - blood cell infiltrate the epidermis.

	Images:		====Images====
	*[[WC]]:		<gallery>
	**[http://commons.wikimedia.org/wiki/File:Dermatomycosis_-_intermed_mag.jpg Dermatomycosis - intermed. mag. (WC)].		Image:Dermatomycosis_-_intermed_mag.jpg \| Dermatomycosis - intermed. mag. (WC)
	**[http://commons.wikimedia.org/wiki/File:Dermatomycosis_-_high_mag.jpg Dermatomycosis - high mag. (WC)].		Image:Dermatomycosis_-_high_mag.jpg \| Dermatomycosis - high mag. (WC)
	**[http://commons.wikimedia.org/wiki/File:Dermatomycosis_-_gms_-_low_mag.jpg Dermatomycosis - GMS stain - low mag. (WC)].		Image:Dermatomycosis_-_gms_-_low_mag.jpg \| Dermatomycosis - GMS stain - low mag. (WC)
	**[http://commons.wikimedia.org/wiki/File:Dermatomycosis_-_gms_-_high_mag.jpg Dermatomycosis - GMS stain - high mag. (WC)].		Image:Dermatomycosis_-_gms_-_high_mag.jpg \| Dermatomycosis - GMS stain - high mag. (WC)
	*www:		</gallery>
	**[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/tinea_pas.jpg Dermatophytosis (ucsf.edu)].<ref>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/tinea.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/tinea.html]. Accessed on: 25 February 2013.</ref>		www:
			*[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/tinea_pas.jpg Dermatophytosis (ucsf.edu)].<ref>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/tinea.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/tinea.html]. Accessed on: 25 February 2013.</ref>

	===Stains===		===Stains===

Michael: /* Verruca plana */

2014-07-09T14:04:14Z

Verruca plana

← Older revision		Revision as of 14:04, 9 July 2014
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	Notes:		Notes:
	*It differs from verruca vulgaris... (1) orthokeratosis, (2) flat surface and base.		*It differs from [[verruca vulgaris]]... (1) orthokeratosis, (2) flat surface and base.

	Images:		====Images====
			www:
	*[http://www.fujita-hu.ac.jp/~tsutsumi/case/case180.htm Verruca plana - several images (fujita-hu.ac.jp)].		*[http://www.fujita-hu.ac.jp/~tsutsumi/case/case180.htm Verruca plana - several images (fujita-hu.ac.jp)].
	*[http://www.dermatopathonline.com/verruca%20plana2.html Verruca plana - several good images (dermatopathonline.com)].		*[http://www.dermatopathonline.com/verruca%20plana2.html Verruca plana - several good images (dermatopathonline.com)].

Michael: /* Verruca plana */

2014-07-09T14:03:17Z

Verruca plana

← Older revision		Revision as of 14:03, 9 July 2014
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	Images:		Images:
	*[http://www.fujita-hu.ac.jp/~tsutsumi/case/case180.htm Verruca plana - several images (fujita-hu.ac.jp)].		*[http://www.fujita-hu.ac.jp/~tsutsumi/case/case180.htm Verruca plana - several images (fujita-hu.ac.jp)].
	*[http://bg.convdocs.org/pars_docs/refs/55/54881/54881_html_m70d4f7e5.jpg Verruca plana (convdocs.org)].<ref>URL: [http://bg.convdocs.org/docs/index-54881.html?page=10 http://bg.convdocs.org/docs/index-54881.html?page=10]. Accessed on: 9 October 2013.</ref>
	*[http://www.dermatopathonline.com/verruca%20plana2.html Verruca plana - several good images (dermatopathonline.com)].		*[http://www.dermatopathonline.com/verruca%20plana2.html Verruca plana - several good images (dermatopathonline.com)].

Michael: /* Lichenoid keratosis */

2014-07-03T18:20:03Z

Lichenoid keratosis

← Older revision		Revision as of 18:20, 3 July 2014
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	==Lichenoid keratosis==		==Lichenoid keratosis==
	*[[AKA]] ''lichen planus-like keratosis''.		*[[AKA]] ''lichen planus-like keratosis''.
	*[[AKA]] ''lichenoid keratosis''.
	{{Main\|Lichenoid keratosis}}		{{Main\|Lichenoid keratosis}}

Michael: /* Lichenoid keratosis */ split out

2014-07-03T18:19:22Z

Lichenoid keratosis: split out

← Older revision		Revision as of 18:19, 3 July 2014
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	*[[AKA]] ''lichen planus-like keratosis''.		*[[AKA]] ''lichen planus-like keratosis''.
	*[[AKA]] ''lichenoid keratosis''.		*[[AKA]] ''lichenoid keratosis''.
			{{Main\|Lichenoid keratosis}}
	~~===General===~~
	*Caucasians - middle age or older.
	*May be a variant of [[seborrheic keratosis]] (with marked inflammation).<ref name=Ref_Derm346>{{~~Ref Derm~~\|~~346~~}}~~</ref>~~

	~~Clinical DDx:<ref name=Ref_Derm346>{{Ref Derm\|346}}</ref>~~
	*[[Basal cell carcinoma]], [[squamous cell carcinoma of the skin]], melanocytic neoplasm.

	~~===Microscopic===~~
	~~Features:<ref name=Ref_Derm347>{{Ref Derm\|347}}</ref>~~
	*Hyperkeratosis.
	*Parakeratosis.
	*Band of inflammatory cells at DE junction (lichenoid inflammation).
	*Dead keratinocytes (Civatte bodies).
	*Dermal melanophages.

	~~DDx:~~
	*[[Lichen planus]] - need clinical correlation (mucosal lesions).
	*[[Drug reaction]].
	*[[Cutaneous T-cell lymphoma]].
	*Regressed melanocytic lesion, esp. [[malignant melanoma]].
	*Lichenoid [[actinic keratosis]] - has atypical hyperchromatic basal cells - esp. at edge of lesion, usu. in the context of [[solar elastosis]].

	~~Images:~~
	*[http://www.dermpathexpert.com/id57.html Lichenoid keratosis (dermpathexpert.com)].

	~~===Sign out===~~
	~~<pre>~~
	~~SKIN LESION, MID-MIDDLE BACK, PUNCH BIOPSY:~~
	~~- LICHENOID KERATOSIS.~~
	~~</pre>~~

	~~====Incompletely excised====~~
	~~<pre>~~
	~~SKIN LESION, LEFT CHEST, PUNCH BIOPSY:~~
	~~- LICHENOID KERATOSIS VERSUS ACTINIC KERATOSIS.~~
	~~- NEGATIVE FOR BASAL CELL CARCINOMA.~~
	~~- SEE COMMENT.~~

	~~COMMENT:~~
	~~No eosinophils are apparent. No melanocytic lesion is identified; however, excision of the~~
	~~whole lesion to exclude a partially regressed melanocytic lesion is suggested.~~
	~~</pre>~~

	==Granuloma annulare==		==Granuloma annulare==

Michael: /* Benign fibrous papule */

2014-06-27T15:39:40Z

Benign fibrous papule

← Older revision		Revision as of 15:39, 27 June 2014
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	Note:		Note:
	*Several variants exist.<ref name=pmid18032900>{{Cite journal \| last1 = Jacyk \| first1 = WK. \| last2 = Rütten \| first2 = A. \| last3 = Requena \| first3 = L. \| title = Fibrous papule of the face with granular cells. \| journal = Dermatology \| volume = 216 \| issue = 1 \| pages = 56-9 \| month = \| year = 2008 \| doi = 10.1159/000109359 \| PMID = 18032900 }}</ref>		*Several variants exist.<ref name=pmid18032900>{{Cite journal \| last1 = Jacyk \| first1 = WK. \| last2 = Rütten \| first2 = A. \| last3 = Requena \| first3 = L. \| title = Fibrous papule of the face with granular cells. \| journal = Dermatology \| volume = 216 \| issue = 1 \| pages = 56-9 \| month = \| year = 2008 \| doi = 10.1159/000109359 \| PMID = 18032900 }}</ref>

			===Images===
			*[http://www.dermaamin.com/site/histopathology-of-the-skin/58-f/1739-fibrous-papule-angiofibroma-.html Fibrous papule (dermaamin.com)].

	===Sign out===		===Sign out===

Michael: /* General */

2014-06-21T12:29:11Z

General

← Older revision		Revision as of 12:29, 21 June 2014
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	===General===		===General===
	*Benign.		*Benign.
	*Looks like zit.		*Looks like a zit.

	===Microscopic===		===Microscopic===