Neuroendocrine neoplasms - Revision history

Michael at 19:55, 5 December 2023

2023-12-05T19:55:03Z

← Older revision		Revision as of 19:55, 5 December 2023
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	*[[CDX2]] -ve/+ve.		*[[CDX2]] -ve/+ve.
	**+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal \| last1 = Saad \| first1 = RS. \| last2 = Ghorab \| first2 = Z. \| last3 = Khalifa \| first3 = MA. \| last4 = Xu \| first4 = M. \| title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. \| journal = World J Gastrointest Surg \| volume = 3 \| issue = 11 \| pages = 159-66 \| month = Nov \| year = 2011 \| doi = 10.4240/wjgs.v3.i11.159 \| PMID = 22180832 }}</ref>		**+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal \| last1 = Saad \| first1 = RS. \| last2 = Ghorab \| first2 = Z. \| last3 = Khalifa \| first3 = MA. \| last4 = Xu \| first4 = M. \| title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. \| journal = World J Gastrointest Surg \| volume = 3 \| issue = 11 \| pages = 159-66 \| month = Nov \| year = 2011 \| doi = 10.4240/wjgs.v3.i11.159 \| PMID = 22180832 }}</ref>
			*Serotonin -ve/+ve.
			**+ve suggests jejuno-ileal origin.{{fact}}

	Hormone products:		Hormone products:

2017-09-03T16:05:12Z

2017-06-30T13:12:23Z

IHC - generic

← Older revision		Revision as of 13:12, 30 June 2017
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	*NSE +ve.		*NSE +ve.
	*[[CD56]] +ve.		*[[CD56]] +ve.
	*Ki-67 - useful for grading.		*[[Ki-67]] - useful for grading.
	*PGP9.5.<ref name=pmid20182342/>		*PGP9.5.<ref name=pmid20182342/>
	*CDX2 -ve/+ve.		*[[CDX2]] -ve/+ve.
	**+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal \| last1 = Saad \| first1 = RS. \| last2 = Ghorab \| first2 = Z. \| last3 = Khalifa \| first3 = MA. \| last4 = Xu \| first4 = M. \| title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. \| journal = World J Gastrointest Surg \| volume = 3 \| issue = 11 \| pages = 159-66 \| month = Nov \| year = 2011 \| doi = 10.4240/wjgs.v3.i11.159 \| PMID = 22180832 }}</ref>		**+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal \| last1 = Saad \| first1 = RS. \| last2 = Ghorab \| first2 = Z. \| last3 = Khalifa \| first3 = MA. \| last4 = Xu \| first4 = M. \| title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. \| journal = World J Gastrointest Surg \| volume = 3 \| issue = 11 \| pages = 159-66 \| month = Nov \| year = 2011 \| doi = 10.4240/wjgs.v3.i11.159 \| PMID = 22180832 }}</ref>

2017-03-05T17:48:27Z

Microscopic - generic: tweak

← Older revision		Revision as of 17:48, 5 March 2017
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	DDx:		DDx:
	*[[Paraganglioma]].		*[[Paraganglioma]].
	*Neoplasm with neuroendocrine differentiation.		*Neoplasm with neuroendocrine differentiation (<30% neuroendocrine component<ref name=pmid26556999>{{Cite journal \| last1 = Kleist \| first1 = B. \| last2 = Poetsch \| first2 = M. \| title = Neuroendocrine differentiation: The mysterious fellow of colorectal cancer. \| journal = World J Gastroenterol \| volume = 21 \| issue = 41 \| pages = 11740-7 \| month = Nov \| year = 2015 \| doi = 10.3748/wjg.v21.i41.11740 \| PMID = 26556999 }}</ref>).

	==Images==		==Images==

2017-03-05T17:45:53Z

Microscopic - generic

← Older revision		Revision as of 17:45, 5 March 2017
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	DDx:		DDx:
	*[[Paraganglioma]].		*[[Paraganglioma]].
			*Neoplasm with neuroendocrine differentiation.

	==Images==		==Images==

2016-04-08T15:24:21Z

IHC - generic

← Older revision		Revision as of 15:24, 8 April 2016
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	*Ki-67 - useful for grading.		*Ki-67 - useful for grading.
	*PGP9.5.<ref name=pmid20182342/>		*PGP9.5.<ref name=pmid20182342/>
			*CDX2 -ve/+ve.
			**+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal \| last1 = Saad \| first1 = RS. \| last2 = Ghorab \| first2 = Z. \| last3 = Khalifa \| first3 = MA. \| last4 = Xu \| first4 = M. \| title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. \| journal = World J Gastrointest Surg \| volume = 3 \| issue = 11 \| pages = 159-66 \| month = Nov \| year = 2011 \| doi = 10.4240/wjgs.v3.i11.159 \| PMID = 22180832 }}</ref>

	Hormone products:		Hormone products:

2016-01-24T04:49:04Z

Site specific

← Older revision		Revision as of 04:49, 24 January 2016
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	==Lung==		==Lung==
	{{Main\|Lung_tumours#Neuroendocrine_tumours}}		{{Main\|Lung_tumours#Neuroendocrine_tumours}}

			==Genitourinary pathology==
			{{Main\|Small cell carcinoma of the prostate gland}}
			{{Main\|Small cell carcinoma of the urinary bladder}}

	==Gastrointestinal tract==		==Gastrointestinal tract==

2014-09-13T17:47:16Z

← Older revision		Revision as of 17:47, 13 September 2014
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			[[Image:Small intestine neuroendocrine tumour high mag.jpg\|thumb\|right\|200px\|Micrograph of a neuroendocrine tumour of the small bowel. [[H&E stain]].]]
	'''Neuroendocrine neoplasms''', also '''neuroendocrine tumours''', are a group of tumours whose behaviour varies from benign to malignant and are found in may different sites. ''Neuroendocrine tumour'' is commonly abbreviated '''NET'''.		'''Neuroendocrine neoplasms''', also '''neuroendocrine tumours''', are a group of tumours whose behaviour varies from benign to malignant and are found in may different sites. ''Neuroendocrine tumour'' is commonly abbreviated '''NET'''.

2014-09-13T08:04:00Z

IHC - generic

2013-05-17T02:23:02Z

Microscopic - generic

← Older revision		Revision as of 02:23, 17 May 2013
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	*[[Paraganglioma]].		*[[Paraganglioma]].

	Images:		==Images==
	*[[WC]]:		<gallery>
	**[http://commons.wikimedia.org/wiki/File:Small_intestine_neuroendocrine_tumour_low_mag.jpg Neuroendocrine tumour - low mag. (WC)].		Image:Small_intestine_neuroendocrine_tumour_low_mag.jpg \| Neuroendocrine tumour - low mag. (WC/Nephron)
	**[http://commons.wikimedia.org/wiki/File:Small_intestine_neuroendocrine_tumour_intermed_mag.jpg Neuroendocrine tumour - intermed. mag. (WC)].		Image:Small_intestine_neuroendocrine_tumour_intermed_mag.jpg \| Neuroendocrine tumour - intermed. mag. (WC/Nephron)
	**[http://commons.wikimedia.org/wiki/File:Small_intestine_neuroendocrine_tumour_high_mag.jpg Neuroendocrine tumour - high mag. (WC)].		Image:Small_intestine_neuroendocrine_tumour_high_mag.jpg \| Neuroendocrine tumour - high mag. (WC/Nephron)
	*www:		</gallery>
	**[http://path.upmc.edu/cases/case7/images/micro3.jpg NET met to liver (upmc.edu)].<ref>URL: [http://path.upmc.edu/cases/case7.html http://path.upmc.edu/cases/case7.html}. Accessed on: 17 December 2011.</ref>		www:
			*[http://path.upmc.edu/cases/case7/images/micro3.jpg NET met to liver (upmc.edu)].<ref>URL: [http://path.upmc.edu/cases/case7.html http://path.upmc.edu/cases/case7.html}. Accessed on: 17 December 2011.</ref>

	=IHC - generic=		=IHC - generic=

← Older revision		Revision as of 16:05, 3 September 2017
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	*[[Basics]].		*[[Basics]].
	*[[Goblet cell carcinoid]].		*[[Goblet cell carcinoid]].
			*[[Mixed neuroendocrine-nonneuroendocrine neoplasm]] (MiNEN).

	=References=		=References=