Necrobiosis lipoidica - Revision history

Michael at 01:54, 31 October 2013

2013-10-31T01:54:35Z

← Older revision		Revision as of 01:54, 31 October 2013
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	==See also==		==See also==
	*[Non-malignant skin disease]].		*[[Non-malignant skin disease]].

	==References==		==References==
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	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Non-malignant skin disease]]

Michael: tweak

2013-10-31T01:53:54Z

tweak

← Older revision		Revision as of 01:53, 31 October 2013
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	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing =
	\| Site =		\| Site = [[skin]]
	\| Assdx = [[diabetes mellitus]], [[rheumatoid arthritis]]		\| Assdx = [[diabetes mellitus]], [[rheumatoid arthritis]]
	\| Syndromes =		\| Syndromes =

Michael at 01:53, 31 October 2013

2013-10-31T01:53:36Z

← Older revision		Revision as of 01:53, 31 October 2013
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	\| Width =		\| Width =
	\| Caption = Necrobiosis lipoidica. [[HPS stain]].		\| Caption = Necrobiosis lipoidica. [[HPS stain]].
	\| Micro = (dermal) palisading [[granuloma]] around necrotic collagen; little mucin; no normal dermis between foci; plasma cells - common;		\| Micro = (dermal) palisading [[granuloma]]s around necrotic collagen; little mucin; no normal dermis between foci; plasma cells - common; +/-involvement of subcutis
	+/-~~involve~~ subcutis
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[granuloma annulare]], [[rheumatoid nodule]]		\| LMDDx = [[granuloma annulare]], [[rheumatoid nodule]]

Michael: split-out

2013-10-31T01:52:51Z

split-out

← Older revision		Revision as of 01:52, 31 October 2013
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	~~#redirect~~ [[Non-~~malignant_skin_disease#Necrobiosis_lipoidica~~]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Necrobiosis_lipoidica_-_low_mag.jpg
			\| Width =
			\| Caption = Necrobiosis lipoidica. [[HPS stain]].
			\| Micro = (dermal) palisading [[granuloma]] around necrotic collagen; little mucin; no normal dermis between foci; plasma cells - common;
			+/-involve subcutis
			\| Subtypes =
			\| LMDDx = [[granuloma annulare]], [[rheumatoid nodule]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site =
			\| Assdx = [[diabetes mellitus]], [[rheumatoid arthritis]]
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			}}
			'''Necrobiosis lipoidica''' is an uncommon granulomatous [[skin]] pathology.

			==General==
			Associated with:
			*[[Diabetes mellitus]] - known as ''necrobiosis lipoidica diabeticorum''.
			*[[Rheumatoid arthritis]].

			==Gross==

			Image:
			<gallery>
			Image:Necrobiosislipoidica.jpg \| Necrobiosis lipoidica. (WC)
			</gallery>

			==Microscopic==
			Features:<ref name=Ref_Derm51>{{Ref Derm\|51}}</ref>
			*Dermal palisading [[granuloma]] around:
			**Necrotic collagen - '''key feature'''.
			***Nuclei "missing" - have undergone karyolysis.
			*Little mucin, no normal dermis between foci.
			*Plasma cells - common.<ref name=dermnetnz_nl>URL: [http://dermnetnz.org/pathology/necrobiosis-lipoidica-path.html http://dermnetnz.org/pathology/necrobiosis-lipoidica-path.html]. Accessed on: 24 January 2012.</ref>
			*May involve adipose tissue.

			DDx:
			*[[Granuloma annulare\|Granuloma a'''nn'''ulare]] - '''m'''ore '''m'''ucin, normal dermis between foci,<ref name=Ref_Derm51>{{Ref Derm\|51}}</ref> plasma cells uncommon,<ref name=dermnetnz_nl/> no fat involvement - usu. more superficial.
			*[[Rheumatoid nodule]].

			===Images===
			<gallery>
			Image:Necrobiosis_lipoidica_-_low_mag.jpg \| Necrobiosis lipoidica - low mag. (WC)
			</gallery>
			www:
			*[http://dermatology.cdlib.org/103/NYU/case_presentations/042004n10.html Necrobiosis lipoidica (dermatology.cdlib.org)].
			*[http://www.drmihm.com/cases/case.cfm?CaseID=53 Necrobiosis lipoidica (drmihm.com)].
			*[http://dermnetnz.org/pathology/necrobiosis-lipoidica-path.html Necrobiosis lipoidica (dermnetnz.org)].

			==See also==
			*[Non-malignant skin disease]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: +cat.

2011-10-22T06:02:48Z

+cat.

← Older revision		Revision as of 06:02, 22 October 2011
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	#redirect [[Non-malignant_skin_disease#Necrobiosis_lipoidica]]		#redirect [[Non-malignant_skin_disease#Necrobiosis_lipoidica]]

			[[Category:Diagnosis]]

Michael: redirect

2011-09-20T03:40:12Z

redirect

New page

#redirect [[Non-malignant_skin_disease#Necrobiosis_lipoidica]]