Myxofibrosarcoma - Revision history

Michael at 12:26, 24 June 2016

2016-06-24T12:26:27Z

← Older revision		Revision as of 12:26, 24 June 2016
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	'''Myxofibrosarcoma''' is a malignant soft tissue tumour, in the [[fibroblastic/myofibroblastic tumours]] group. It is also known as '''myxoid malignant fibrous histiocytoma''' or '''myxoid MFH'''.<ref name=pmid16008697>{{Cite journal \| last1 = Fujimura \| first1 = T. \| last2 = Okuyama \| first2 = R. \| last3 = Terui \| first3 = T. \| last4 = Okuno \| first4 = K. \| last5 = Masu \| first5 = A. \| last6 = Masu \| first6 = T. \| last7 = Chiba \| first7 = S. \| last8 = Kunii \| first8 = T. \| last9 = Tagami \| first9 = H. \| title = Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. \| journal = J Cutan Pathol \| volume = 32 \| issue = 7 \| pages = 512-5 \| month = Aug \| year = 2005 \| doi = 10.1111/j.0303-6987.2005.00368.x \| PMID = 16008697 }}</ref>		'''Myxofibrosarcoma''' is a malignant soft tissue tumour, in the [[fibroblastic/myofibroblastic tumours]] group. It is also known as '''myxoid [[malignant fibrous histiocytoma]]''' or '''myxoid MFH'''.<ref name=pmid16008697>{{Cite journal \| last1 = Fujimura \| first1 = T. \| last2 = Okuyama \| first2 = R. \| last3 = Terui \| first3 = T. \| last4 = Okuno \| first4 = K. \| last5 = Masu \| first5 = A. \| last6 = Masu \| first6 = T. \| last7 = Chiba \| first7 = S. \| last8 = Kunii \| first8 = T. \| last9 = Tagami \| first9 = H. \| title = Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. \| journal = J Cutan Pathol \| volume = 32 \| issue = 7 \| pages = 512-5 \| month = Aug \| year = 2005 \| doi = 10.1111/j.0303-6987.2005.00368.x \| PMID = 16008697 }}</ref>

	It should '''not''' be confused with ''[[low-grade fibromyxoid sarcoma]]''.<ref name=pmid8650138>{{Cite journal \| last1 = Mentzel \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| last3 = Fletcher \| first3 = CD. \| title = [Low malignancy myxofibrosarcoma versus low malignancy fibromyxoid sarcoma. Distinct entities with similar names but different clinical course]. \| journal = Pathologe \| volume = 17 \| issue = 2 \| pages = 116-21 \| month = Mar \| year = 1996 \| doi = \| PMID = 8650138 }}</ref>		It should '''not''' be confused with ''[[low-grade fibromyxoid sarcoma]]''.<ref name=pmid8650138>{{Cite journal \| last1 = Mentzel \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| last3 = Fletcher \| first3 = CD. \| title = [Low malignancy myxofibrosarcoma versus low malignancy fibromyxoid sarcoma. Distinct entities with similar names but different clinical course]. \| journal = Pathologe \| volume = 17 \| issue = 2 \| pages = 116-21 \| month = Mar \| year = 1996 \| doi = \| PMID = 8650138 }}</ref>

Michael: /* References */

2016-06-24T12:26:00Z

References

← Older revision		Revision as of 12:26, 24 June 2016
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	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Soft tissue lesions]]

Michael at 12:25, 24 June 2016

2016-06-24T12:25:26Z

← Older revision		Revision as of 12:25, 24 June 2016
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	'''Myxofibrosarcoma''' is a malignant soft tissue tumour, in the [[fibroblastic/myofibroblastic tumours]] group.		'''Myxofibrosarcoma''' is a malignant soft tissue tumour, in the [[fibroblastic/myofibroblastic tumours]] group. It is also known as '''myxoid malignant fibrous histiocytoma''' or '''myxoid MFH'''.<ref name=pmid16008697>{{Cite journal \| last1 = Fujimura \| first1 = T. \| last2 = Okuyama \| first2 = R. \| last3 = Terui \| first3 = T. \| last4 = Okuno \| first4 = K. \| last5 = Masu \| first5 = A. \| last6 = Masu \| first6 = T. \| last7 = Chiba \| first7 = S. \| last8 = Kunii \| first8 = T. \| last9 = Tagami \| first9 = H. \| title = Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. \| journal = J Cutan Pathol \| volume = 32 \| issue = 7 \| pages = 512-5 \| month = Aug \| year = 2005 \| doi = 10.1111/j.0303-6987.2005.00368.x \| PMID = 16008697 }}</ref>

	It should '''not''' be confused with ''[[low-grade fibromyxoid sarcoma]]''.<ref name=pmid8650138>{{Cite journal \| last1 = Mentzel \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| last3 = Fletcher \| first3 = CD. \| title = [Low malignancy myxofibrosarcoma versus low malignancy fibromyxoid sarcoma. Distinct entities with similar names but different clinical course]. \| journal = Pathologe \| volume = 17 \| issue = 2 \| pages = 116-21 \| month = Mar \| year = 1996 \| doi = \| PMID = 8650138 }}</ref>		It should '''not''' be confused with ''[[low-grade fibromyxoid sarcoma]]''.<ref name=pmid8650138>{{Cite journal \| last1 = Mentzel \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| last3 = Fletcher \| first3 = CD. \| title = [Low malignancy myxofibrosarcoma versus low malignancy fibromyxoid sarcoma. Distinct entities with similar names but different clinical course]. \| journal = Pathologe \| volume = 17 \| issue = 2 \| pages = 116-21 \| month = Mar \| year = 1996 \| doi = \| PMID = 8650138 }}</ref>
	*[[AKA]] ''myxoid malignant fibrous histiocytoma'' or ''myxoid MFH''.<ref>{{Cite journal \| last1 = Fujimura \| first1 = T. \| last2 = Okuyama \| first2 = R. \| last3 = Terui \| first3 = T. \| last4 = Okuno \| first4 = K. \| last5 = Masu \| first5 = A. \| last6 = Masu \| first6 = T. \| last7 = Chiba \| first7 = S. \| last8 = Kunii \| first8 = T. \| last9 = Tagami \| first9 = H. \| title = Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. \| journal = J Cutan Pathol \| volume = 32 \| issue = 7 \| pages = 512-5 \| month = Aug \| year = 2005 \| doi = 10.1111/j.0303-6987.2005.00368.x \| PMID = 16008697 }}</ref>
	==General==		==General==
	*Malignant.		*Malignant.

Michael: split out

2016-06-24T12:24:42Z

split out

← Older revision		Revision as of 12:24, 24 June 2016
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	~~#redirect~~ [[Fibroblastic/~~myofibroblastic_tumours#Myxofibrosarcoma~~]]		'''Myxofibrosarcoma''' is a malignant soft tissue tumour, in the [[fibroblastic/myofibroblastic tumours]] group.

			It should '''not''' be confused with ''[[low-grade fibromyxoid sarcoma]]''.<ref name=pmid8650138>{{Cite journal \| last1 = Mentzel \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| last3 = Fletcher \| first3 = CD. \| title = [Low malignancy myxofibrosarcoma versus low malignancy fibromyxoid sarcoma. Distinct entities with similar names but different clinical course]. \| journal = Pathologe \| volume = 17 \| issue = 2 \| pages = 116-21 \| month = Mar \| year = 1996 \| doi = \| PMID = 8650138 }}</ref>
			*[[AKA]] ''myxoid malignant fibrous histiocytoma'' or ''myxoid MFH''.<ref>{{Cite journal \| last1 = Fujimura \| first1 = T. \| last2 = Okuyama \| first2 = R. \| last3 = Terui \| first3 = T. \| last4 = Okuno \| first4 = K. \| last5 = Masu \| first5 = A. \| last6 = Masu \| first6 = T. \| last7 = Chiba \| first7 = S. \| last8 = Kunii \| first8 = T. \| last9 = Tagami \| first9 = H. \| title = Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. \| journal = J Cutan Pathol \| volume = 32 \| issue = 7 \| pages = 512-5 \| month = Aug \| year = 2005 \| doi = 10.1111/j.0303-6987.2005.00368.x \| PMID = 16008697 }}</ref>
			==General==
			*Malignant.
			*Usually older people, superficial (skin/dermis) and extremities (arm, legs).<ref name=Ref_WMSP612-3>{{Ref WMSP\|612-3}}</ref><ref name=pmid17197925/>
			*Prognosis better than [[pleomorphic undifferentiated sarcoma]].
			**Metastatic potential inversely related to component/portion that is myxoid.<ref name=pmid192434>{{Cite journal \| last1 = Weiss \| first1 = SW. \| last2 = Enzinger \| first2 = FM. \| title = Myxoid variant of malignant fibrous histiocytoma. \| journal = Cancer \| volume = 39 \| issue = 4 \| pages = 1672-85 \| month = Apr \| year = 1977 \| doi = \| PMID = 192434 }}</ref>

			==Microscopic==
			Features:<ref name=Ref_WMSP612-3>{{Ref WMSP\|612-3}}</ref>
			*Discontinuous fibrous septae.
			*Myxoid background.
			*Variable cellularity and nuclear pleomorphism.
			*Spindle cells or epithelioid cells.<ref name=pmid17197925/>
			*Curvilinear vessels.<ref name=pmid17197925>{{Cite journal \| last1 = Nascimento \| first1 = AF. \| last2 = Bertoni \| first2 = F. \| last3 = Fletcher \| first3 = CD. \| title = Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases. \| journal = Am J Surg Pathol \| volume = 31 \| issue = 1 \| pages = 99-105 \| month = Jan \| year = 2007 \| doi = 10.1097/01.pas.0000213379.94547.e7 \| PMID = 17197925 }}</ref>

			DDx:
			*[[Liposarcoma\|Myxoid liposarcoma]].
			*[[Low-grade fibromyxoid sarcoma]] - alternating fibrous and myxoid areas.<ref name=pmid8650138/>
			*[[Myxoma]].

			Image:
			*[http://www.sarcomaimages.com/sub.php?v=sample-case&p=myxofibrosarcoma-myxoid-mfh Myxofibrosarcoma (sarcomaimages.com)].

			==IHC==
			*Vimentin +ve -- otherwise non-distinctive.<ref name=Ref_WMSP612-3>{{Ref WMSP\|612-3}}</ref>

			==See also==
			*[[Fibroblastic/myofibroblastic tumours]].

			==References==
			{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: +cat.

2011-10-20T04:56:28Z

+cat.

← Older revision		Revision as of 04:56, 20 October 2011
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	#redirect [[Fibroblastic/myofibroblastic_tumours#Myxofibrosarcoma]]		#redirect [[Fibroblastic/myofibroblastic_tumours#Myxofibrosarcoma]]

			[[Category:Diagnosis]]

Michael: redirect

2011-10-08T14:57:06Z

redirect

New page

#redirect [[Fibroblastic/myofibroblastic_tumours#Myxofibrosarcoma]]