Medical lung diseases - Revision history

Michael: /* Smoking associated disease */

2017-03-23T14:54:26Z

Smoking associated disease

← Older revision		Revision as of 14:54, 23 March 2017
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	=[[Smoking]] associated disease=		=[[Smoking]] associated disease=
	{{Main\|Smoking}}		{{Main\|Smoking}}
	*RB ~~= respiratory bronchiolitis~~.		*Respiratory bronchiolitis (RB).
	*~~RBILD =~~ [[~~respiratory~~ bronchiolitis interstitial lung disease]].		*[[Respiratory bronchiolitis interstitial lung disease]] (RBILD).
	*~~DIP =~~ [[~~desquamative~~ interstitial pneumonia]].		*[[Desquamative interstitial pneumonia]] (DIP).
	*Eosinophilic granuloma (of lung) - [[AKA]] [[pulmonary langerhans cell histiocytosis]].		*Eosinophilic granuloma (of lung) - [[AKA]] [[pulmonary langerhans cell histiocytosis]].
	*[[Smoking-related interstitial fibrosis]] (SRIF).		*[[Smoking-related interstitial fibrosis]] (SRIF).

Michael: /* Smoking associated disease */

2017-03-23T14:53:48Z

Smoking associated disease

← Older revision		Revision as of 14:53, 23 March 2017
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	*DIP = [[desquamative interstitial pneumonia]].		*DIP = [[desquamative interstitial pneumonia]].
	*Eosinophilic granuloma (of lung) - [[AKA]] [[pulmonary langerhans cell histiocytosis]].		*Eosinophilic granuloma (of lung) - [[AKA]] [[pulmonary langerhans cell histiocytosis]].
			*[[Smoking-related interstitial fibrosis]] (SRIF).

	All of the above are ~~assoc.~~ with smoking. RBILD & DIP are considered by many to be on a continuum, i.e. RBILD is early DIP.		All of the above are associated with smoking. RBILD & DIP are considered by many to be on a continuum, i.e. RBILD is early DIP.

	==Respiratory bronchiolitis==		==Respiratory bronchiolitis==

Michael: replace

2016-11-28T21:40:17Z

replace

← Older revision		Revision as of 21:40, 28 November 2016
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	=Eosinophilic pneumonia=		=Eosinophilic pneumonia=
	Specific entities:<ref name=emedicine301070>[http://emedicine.medscape.com/article/301070-overview http://emedicine.medscape.com/article/301070-overview]</ref>		Specific entities:<ref name=emedicine301070>[http://emedicine.medscape.com/article/301070-overview http://emedicine.medscape.com/article/301070-overview]</ref>
	*[[Churg-Strauss syndrome]].		*[[Eosinophilic granulomatosis with polyangiitis]] (Churg-Strauss syndrome).
	*Acute eosinophilic pneumonia.		*Acute eosinophilic pneumonia.
	*Chronic eosinophilic pneumonia.		*Chronic eosinophilic pneumonia.

Michael: /* Granulomatous lung disease */

2016-11-25T11:43:32Z

Granulomatous lung disease

← Older revision		Revision as of 11:43, 25 November 2016
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	*Talc granulomatosis.		*Talc granulomatosis.
	*Sarcoidosis.		*Sarcoidosis.
	*Wegener granulomatosis.		*[[Granulomatosis with polyangiitis]] (Wegener granulomatosis).

	==Sarcoidosis==		==Sarcoidosis==

Michael: /* Constrictive bronchiolitis */ fix sp

2016-09-14T02:40:24Z

Constrictive bronchiolitis: fix sp

← Older revision		Revision as of 02:40, 14 September 2016
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	==Constrictive bronchiolitis==		==Constrictive bronchiolitis==
	*[[AKA]] ''bronchiolitis obliterans'', [[AKA]] ''obliterative broncholitis'',<ref name=pmid16493150/> [[AKA]] bronchiolitis obliterans syndrome (BOS).<ref name=pmid18707652>{{Cite journal \| last1 = Sato \| first1 = M. \| last2 = Keshavjee \| first2 = S. \| title = Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. \| journal = Semin Thorac Cardiovasc Surg \| volume = 20 \| issue = 2 \| pages = 173-82 \| month = \| year = 2008 \| doi = 10.1053/j.semtcvs.2008.05.002 \| PMID = 18707652 }}</ref>		*[[AKA]] ''bronchiolitis obliterans'', [[AKA]] ''obliterative broncholitis'',<ref name=pmid16493150/> [[AKA]] bronchiolitis obliterans syndrome (BOS).<ref name=pmid18707652>{{Cite journal \| last1 = Sato \| first1 = M. \| last2 = Keshavjee \| first2 = S. \| title = Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. \| journal = Semin Thorac Cardiovasc Surg \| volume = 20 \| issue = 2 \| pages = 173-82 \| month = \| year = 2008 \| doi = 10.1053/j.semtcvs.2008.05.002 \| PMID = 18707652 }}</ref>
	{{Main\|Constrictive ~~bronchioloitis~~}}		{{Main\|Constrictive bronchiolitis}}

	==Diffuse lung diseases==		==Diffuse lung diseases==

Michael: /* Constrictive bronchiolitis */ split out

2016-09-14T02:40:09Z

Constrictive bronchiolitis: split out

← Older revision		Revision as of 02:40, 14 September 2016
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	==Constrictive bronchiolitis==		==Constrictive bronchiolitis==
	*[[AKA]] ''bronchiolitis obliterans'', [[AKA]] ''obliterative broncholitis'',<ref name=pmid16493150/> [[AKA]] bronchiolitis obliterans syndrome (BOS).<ref name=pmid18707652>{{Cite journal \| last1 = Sato \| first1 = M. \| last2 = Keshavjee \| first2 = S. \| title = Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. \| journal = Semin Thorac Cardiovasc Surg \| volume = 20 \| issue = 2 \| pages = 173-82 \| month = \| year = 2008 \| doi = 10.1053/j.semtcvs.2008.05.002 \| PMID = 18707652 }}</ref>		*[[AKA]] ''bronchiolitis obliterans'', [[AKA]] ''obliterative broncholitis'',<ref name=pmid16493150/> [[AKA]] bronchiolitis obliterans syndrome (BOS).<ref name=pmid18707652>{{Cite journal \| last1 = Sato \| first1 = M. \| last2 = Keshavjee \| first2 = S. \| title = Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. \| journal = Semin Thorac Cardiovasc Surg \| volume = 20 \| issue = 2 \| pages = 173-82 \| month = \| year = 2008 \| doi = 10.1053/j.semtcvs.2008.05.002 \| PMID = 18707652 }}</ref>
	~~===General===~~		{{Main\|Constrictive bronchioloitis}}
	*'''''Not''''' the same as (idiopathic) ''[[bronchiolitis obliterans organizing pneumonia]] (BOOP)'' - in short:
	**BOOP: clogs the airway, has Masson bodies, treated with steroids - good prognosis.
	**Constrictive bronchiolitis: fibrosis around airways, crappy prognosis.

	*No good treatment.
	*Progressive.

	~~Etiology/associations:<ref name=pmid16493150/>~~
	*Post-infectious.
	**Viral, e.g. [[Adenovirus]].
	**Mycoplasma.
	*Post-lung transplant.<ref name=pmid19896545/>
	*Post-hematopoietic stem cell transplantation
	**Associated with GVHD.<ref name=pmid19896545>{{Cite journal \| last1 = Chien \| first1 = JW. \| last2 = Duncan \| first2 = S. \| last3 = Williams \| first3 = KM. \| last4 = Pavletic \| first4 = SZ. \| title = Bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation-an increasingly recognized manifestation of chronic graft-versus-host disease. \| ~~journal = Biol Blood Marrow Transplant \| volume = 16 \| issue = 1 Suppl \| pages = S106-14 \| month = Jan \| year = 2010 \| doi = 10.1016/j.bbmt.2009.11.002 \| PMID = 19896545 }}</ref>~~
	*Connective tissue disease, mostly [[rheumatoid arthritis]].
	*[[Ulcerative colitis]].
	*Drugs - penicillamine.
	*Toxins.
	*Idiopathic.

	~~===Microscopic===~~
	Features:<ref name=pmid16493150>{{Cite journal \| last1 = Visscher \| first1 = DW. \| last2 = Myers \| first2 = JL. \| title = Bronchiolitis: the pathologist's perspective. \| journal = Proc Am Thorac Soc \| volume = 3 \| issue = 1 \| pages = 41-7 \| month = \| year = 2006 \| doi = 10.1513/pats.200512-124JH \| PMID = 16493150 \| url = http://pats.atsjournals.org/cgi/content/full/3/1/41 }}</ref>
	~~#Bronchiolitis - mononuclear and neutrophilic.~~
	~~#*May be minimal late in the disease.~~
	~~#Fibrosis - submucosal and peribronchiolar.~~
	~~#*Can be patchy.~~

	~~Notes:~~
	*Bronchioles = noncartilagenous airways usu. < 2 mm in diameter.<ref name=pmid16493150/>

	~~====Images====~~
	*[http://www.atsjournals.org/doi/abs/10.1513/pats.200512-124JH?journalCode=pats#readcube-epdf Constrictive bronchiolitis - Figure 4 (atsjournals.org)].<ref name=pmid16493150>{{Cite journal \| last1 = Visscher \| first1 = DW. \| last2 = Myers \| first2 = JL. \| title = Bronchiolitis: the pathologist's perspective. \| journal = Proc Am Thorac Soc \| volume = 3 \| issue = 1 \| pages = 41-7 \| month = \| year = 2006 \| doi = 10.1513/pats.200512-124JH \| PMID = 16493150 \| url = http://pats.atsjournals.org/cgi/content/full/3/1/41 }}~~</ref>~~

	~~===Stains===~~
	*Elastic trichrome - useful for delineation of obliterated bronchioles.

	==Diffuse lung diseases==		==Diffuse lung diseases==

Michael: /* Constrictive bronchiolitis */

2016-09-14T02:34:12Z

Constrictive bronchiolitis

← Older revision		Revision as of 02:34, 14 September 2016
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	*Bronchioles = noncartilagenous airways usu. < 2 mm in diameter.<ref name=pmid16493150/>		*Bronchioles = noncartilagenous airways usu. < 2 mm in diameter.<ref name=pmid16493150/>

	Images:		====Images====
	*[http://pats.atsjournals.org/cgi/content/full/3/1/41/~~FIG4 Constrictive bronchiolitis (atsjournals.org)].~~		*[http://www.atsjournals.org/doi/abs/10.1513/pats.200512-124JH?journalCode=pats#readcube-epdf Constrictive bronchiolitis - Figure 4 (atsjournals.org)].<ref name=pmid16493150>{{Cite journal \| last1 = Visscher \| first1 = DW. \| last2 = Myers \| first2 = JL. \| title = Bronchiolitis: the pathologist's perspective. \| journal = Proc Am Thorac Soc \| volume = 3 \| issue = 1 \| pages = 41-7 \| month = \| year = 2006 \| doi = 10.1513/pats.200512-124JH \| PMID = 16493150 \| url = http://pats.atsjournals.org/cgi/content/full/3/1/41 }}</ref>

	===Stains===		===Stains===

Michael: /* Smoking associated disease */

2016-05-11T00:02:04Z

Smoking associated disease

← Older revision		Revision as of 00:02, 11 May 2016
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	{{Main\|Smoking}}		{{Main\|Smoking}}
	*RB = respiratory bronchiolitis.		*RB = respiratory bronchiolitis.
	*RBILD = respiratory bronchiolitis interstitial lung disease.		*RBILD = [[respiratory bronchiolitis interstitial lung disease]].
	*DIP = desquamative interstitial pneumonia.		*DIP = [[desquamative interstitial pneumonia]].
	*Eosinophilic granuloma (of lung) - [[AKA]] pulmonary langerhans cell histiocytosis.		*Eosinophilic granuloma (of lung) - [[AKA]] [[pulmonary langerhans cell histiocytosis]].

	All of the above are assoc. with smoking. RBILD & DIP are considered by many to be on a continuum, i.e. RBILD is early DIP.		All of the above are assoc. with smoking. RBILD & DIP are considered by many to be on a continuum, i.e. RBILD is early DIP.

Michael: /* Lymphocytic lesions of the lung */

2016-05-07T02:32:21Z

Lymphocytic lesions of the lung

← Older revision		Revision as of 02:32, 7 May 2016
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	\|stains to exclude lymphoma; germinal centres do not exclude [[lymphoma]]		\|stains to exclude lymphoma; germinal centres do not exclude [[lymphoma]]
	\|-		\|-
	\|Lymphoma (BALToma)		\|Lymphoma ([[BALToma]])
	\|abundant lymphoid cells usu. in nodules		\|abundant lymphoid cells usu. in nodules
	\|nodules / interstitial pattern		\|nodules / interstitial pattern
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	==Pulmonary nodular lymphoid hyperplasia==		==Pulmonary nodular lymphoid hyperplasia==
	{{Main\|Pulmonary nodular lymphoid hyperplasia}}		{{Main\|Pulmonary nodular lymphoid hyperplasia}}

			==Lymphoma of the lung==
			{{Main\|Lymphoma of the lung}}

	=[[Smoking]] associated disease=		=[[Smoking]] associated disease=

Michael: /* Pulmonary nodular lymphoid hyperplasia */ split out

2016-04-18T03:31:19Z

Pulmonary nodular lymphoid hyperplasia: split out

← Older revision		Revision as of 03:31, 18 April 2016
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	==Pulmonary nodular lymphoid hyperplasia==		==Pulmonary nodular lymphoid hyperplasia==
	*[[AKA]] pseudolymphoma - a term some dislike.<ref name=afip_vol2_277>AFIP atlas of nontumour pathology. 2002. Vo. 2. P.277. ISBN 1-881041-79-4.</ref>		{{Main\|Pulmonary nodular lymphoid hyperplasia}}
	~~===General===~~
	*Definition - reactive lymphoid cells.

	~~===Gross/radiology===~~
	*Has nodules radiographically.

	~~===Microscopic===~~
	~~Features:<ref name=afip_vol2_277>AFIP atlas of nontumour pathology. 2002. Vo. 2. P.277. ISBN 1-881041-79-4.</ref>~~
	*Reactive lymphoid nodules.

	~~Notes:<ref name=afip_vol2_281>AFIP atlas of nontumour pathology. 2002. Vo. 2. P.281. ISBN 1-881041-79-4.</ref>~~
	*Presence of germinal centres do '''not''' exclude lymphoma - may still be a [[BALToma]].
	**BALT = bronchial/bronchus associated lymphoid ~~tissue.~~

	~~DDx:~~
	*[[Lymphoma]], specifically [[MALToma\|MALTomas/BALTomas]].
	*[[Lymphocytic interstitial pneumonia]].
	*Follicular bronchiolitis.

	=[[Smoking]] associated disease=		=[[Smoking]] associated disease=