Michael: fix format

2015-06-05T02:30:41Z

fix format

← Older revision		Revision as of 02:30, 5 June 2015
Line 1:		Line 1:
	'''Maternal floor infarction''', abbreviated ''MFI'', is a pathology of the [[placenta]].		'''Maternal floor infarction''', abbreviated '''MFI''', is a pathology of the [[placenta]].

	It is formally known as '''placental maternal floor infarction'''. It is also known as '''massive perivillous fibrin deposition'''.<ref name=Ref_Placenta367>{{Ref Placenta\|367}}</ref>		It is formally known as '''placental maternal floor infarction'''. It is also known as '''massive perivillous fibrin deposition'''.<ref name=Ref_Placenta367>{{Ref Placenta\|367}}</ref>

Michael: small tweak

2015-06-05T02:30:29Z

small tweak

← Older revision		Revision as of 02:30, 5 June 2015
Line 1:		Line 1:
	'''Maternal floor infarction''', abbreviated ''MFI'', is a pathology of the [[placenta]].		'''Maternal floor infarction''', abbreviated ''MFI'', is a pathology of the [[placenta]].

	It is formally known as ''placental maternal floor infarction''. It is also known as '''massive perivillous fibrin deposition'''.<ref name=Ref_Placenta367>{{Ref Placenta\|367}}</ref>		It is formally known as '''placental maternal floor infarction'''. It is also known as '''massive perivillous fibrin deposition'''.<ref name=Ref_Placenta367>{{Ref Placenta\|367}}</ref>

	==General==		==General==
	*'''''Not''''' a true ~~infact~~.		*'''''Not''''' a true infarct.
	**It is really fibrin deposition.<ref name=Ref_TPoSP178>{{Ref TPoSP\|178}}</ref>		**It is really fibrin deposition.<ref name=Ref_TPoSP178>{{Ref TPoSP\|178}}</ref>

Line 33:		Line 33:
	*[[Placental infarction]].		*[[Placental infarction]].

	Images:		===Images===
	*[http://www.flickr.com/photos/jian-hua_qiao_md/3987724630/ Maternal floor infarct (flickr.com)].		*[http://www.flickr.com/photos/jian-hua_qiao_md/3987724630/ Maternal floor infarct (flickr.com)].
	*[http://www.flickr.com/photos/jian-hua_qiao_md/3986970923/ Maternal floor infarct (flickr.com)].		*[http://www.flickr.com/photos/jian-hua_qiao_md/3986970923/ Maternal floor infarct (flickr.com)].

Michael: split out

2015-06-05T02:29:33Z

split out

← Older revision		Revision as of 02:29, 5 June 2015
Line 1:		Line 1:
	~~#redirect~~ [[Placenta#Maternal floor ~~infarction~~]]		'''Maternal floor infarction''', abbreviated ''MFI'', is a pathology of the [[placenta]].

			It is formally known as ''placental maternal floor infarction''. It is also known as '''massive perivillous fibrin deposition'''.<ref name=Ref_Placenta367>{{Ref Placenta\|367}}</ref>

			==General==
			*'''''Not''''' a true infact.
			**It is really fibrin deposition.<ref name=Ref_TPoSP178>{{Ref TPoSP\|178}}</ref>

			Associations:
			*[[Intrauterine growth restriction]] (IUGR).<ref name=pmid18641412>{{Cite journal \| last1 = Roberts \| first1 = DJ. \| last2 = Post \| first2 = MD. \| title = The placenta in pre-eclampsia and intrauterine growth restriction. \| journal = J Clin Pathol \| volume = 61 \| issue = 12 \| pages = 1254-60 \| month = Dec \| year = 2008 \| doi = 10.1136/jcp.2008.055236 \| PMID = 18641412 }}</ref><ref name=pmid11910510>{{Cite journal \| last1 = Katzman \| first1 = PJ. \| last2 = Genest \| first2 = DR. \| title = Maternal floor infarction and massive perivillous fibrin deposition: histological definitions, association with intrauterine fetal growth restriction, and risk of recurrence. \| journal = Pediatr Dev Pathol \| volume = 5 \| issue = 2 \| pages = 159-64 \| month = \| year = \| doi = 10.1007/s10024-001-0195-y \| PMID = 11910510 }}</ref>
			*Anti-phospholipid antibody (APLA) syndrome.<ref name=pmid12066949>{{cite journal \|author=Sebire NJ, Backos M, Goldin RD, Regan L \|title=Placental massive perivillous fibrin deposition associated with antiphospholipid antibody syndrome \|journal=BJOG \|volume=109 \|issue=5 \|pages=570–3 \|year=2002 \|month=May \|pmid=12066949 \|doi= \|url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1470-0328&date=2002&volume=109&issue=5&spage=570}}</ref>
			**APLA is associated with recurrent miscarriage - can be treated with heparin + ASA.<ref name=pmid12066949/>
			*Pregnancy-induced [[hypertension]].<ref name=pmid8569189>{{Cite journal \| last1 = Kanfer \| first1 = A. \| last2 = Bruch \| first2 = JF. \| last3 = Nguyen \| first3 = G. \| last4 = He \| first4 = CJ. \| last5 = Delarue \| first5 = F. \| last6 = Flahault \| first6 = A. \| last7 = Nessmann \| first7 = C. \| last8 = Uzan \| first8 = S. \| title = Increased placental antifibrinolytic potential and fibrin deposits in pregnancy-induced hypertension and preeclampsia. \| journal = Lab Invest \| volume = 74 \| issue = 1 \| pages = 253-8 \| month = Jan \| year = 1996 \| doi = \| PMID = 8569189 }}</ref>

			==Gross==
			Features:<ref name=Ref_Placenta368>{{Ref Placenta\|368}}</ref>
			*+/-Thickened placenta.
			*Maternal aspect of placental disc irregular or lobulated appearance.
			*+/-Yellowish discolourization.

			==Microscopic==
			Features:
			*Extensive fibrin deposition around villi on maternal aspect - see: ''[[Perivillous fibrin deposition]]''.
			**Described as having a "net-like" pattern.<ref name=Ref_Placenta368>{{Ref Placenta\|368}}</ref>
			**"Extensive" - either of the following:<ref name=pmid11910510/><ref>AFIP - Placental Pathology. P.135. ISBN: 1-881041-89-1. 2004.</ref>
			**#Micro: one slide with >50% of villi involved.
			*#Gross: full thickness involvement.
			**#Micro: maternal floor has at least 3 mm of fibrin on one slide.
			*#Gross: maternal floor diffusely involved.

			DDx:
			*[[Perivillous fibrin deposition]] - less perivillous fibrin.
			*[[Placental infarction]].

			Images:
			*[http://www.flickr.com/photos/jian-hua_qiao_md/3987724630/ Maternal floor infarct (flickr.com)].
			*[http://www.flickr.com/photos/jian-hua_qiao_md/3986970923/ Maternal floor infarct (flickr.com)].
			*[http://path.upmc.edu/cases/case224.html Maternal floor infarct - several images (upmc.edu)].

			==Sign out==
			<pre>
			PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, BIRTH:
			- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS.
			- FETAL MEMBRANES WITHIN NORMAL LIMITS.
			- SMALL PLACENTAL DISC WITH MASSIVE PERIVILLOUS FIBRIN DEPOSITION, SEE COMMENT.

			COMMENT:
			Massive perivillous fibrin deposition (MPVFD) is associated with intrauterine
			growth restriction (IUGR). MPVFD is described in association with in
			anti-phospholipid antibody (APLA) syndrome, pregnancy-induced hypertension and
			congenital infections. Perivillous fibrin deposition may be seen in diabetes.

			There is no apparent infection. Changes suggestive of decidual vasculopathy
			are not apparent. Changes suggestive of fetal thrombotic vasculopathy are
			not identified.
			</pre>

			==See also==
			*[[Placenta]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Placenta]]

Michael: redirect

2013-01-21T20:01:30Z

redirect

New page

#redirect [[Placenta#Maternal floor infarction]]

[[Category:Diagnosis]]

Maternal floor infarction - Revision history

Michael: fix format

Michael: small tweak

Michael: split out

Michael: redirect