Lymphocytic interstitial pneumonia - Revision history

Michael at 13:30, 10 May 2016

2016-05-10T13:30:15Z

← Older revision		Revision as of 13:30, 10 May 2016
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	\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles		\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[lymphoma]], [[follicular bronchitis/bronchiolitis]], [[pulmonary nodular lymphoid hyperplasia\|nodular lymphoid hyperplasia]]		\| LMDDx = [[lymphoma]] - see ''[[lymphoma of lung]]'', [[follicular bronchitis/bronchiolitis]], [[pulmonary nodular lymphoid hyperplasia\|nodular lymphoid hyperplasia]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

Michael: +images

2016-05-10T05:05:46Z

+images

← Older revision		Revision as of 05:05, 10 May 2016
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Lymphocytic interstitial pneumonia -- intermed mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Lymphocytic interstitial pneumonia. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles		\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles
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	===Images===		===Images===
	www:		====Case====
			<gallery>
			Image: Lymphocytic interstitial pneumonia -- extremely low mag.jpg \| LIP - ext. low mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia -- very low mag.jpg \| LIP - very low mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia -- low mag.jpg \| LIP - low mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia -- intermed mag.jpg \| LIP - intermed. mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia -- high mag.jpg \| LIP - high mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia -- very high mag.jpg \| LIP - very high mag. (WC/Nephron)
			<gallery/>
			<gallery>
			Image: Lymphocytic interstitial pneumonia and normal -- very low mag.jpg \| LIP & normal - very low mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia and normal -- low mag.jpg \| LIP & normal - low mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia and normal - alt -- low mag.jpg \| LIP & normal - low mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia and normal -- intermed mag.jpg \| LIP & normal - intermed mag. (WC/Nephron)
			Image: Lymphocytic interstitial pneumonia and normal -- high mag.jpg \| LIP & normal - high mag. (WC/Nephron)
			</gallery>
			====www====
	*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].		*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].
	*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].		*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].

Michael at 03:33, 18 April 2016

2016-04-18T03:33:53Z

← Older revision		Revision as of 03:33, 18 April 2016
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	\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles		\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[lymphoma]], [[follicular bronchitis/bronchiolitis]], nodular lymphoid hyperplasia		\| LMDDx = [[lymphoma]], [[follicular bronchitis/bronchiolitis]], [[pulmonary nodular lymphoid hyperplasia\|nodular lymphoid hyperplasia]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

Michael: /* Microscopic */

2016-04-18T03:33:20Z

Microscopic

← Older revision		Revision as of 03:33, 18 April 2016
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	*[[Lymphoma]].		*[[Lymphoma]].
	*[[Follicular bronchitis/bronchiolitis]].		*[[Follicular bronchitis/bronchiolitis]].
	*Nodular lymphoid hyperplasia.		*[[Pulmonary nodular lymphoid hyperplasia\|Nodular lymphoid hyperplasia]].
	**This is determined in part by radiology; it has nodules radiographically.		**This is determined in part by radiology; it has nodules radiographically.
	*[[Non-specific interstitial pneumonia]] - less inflammation.		*[[Non-specific interstitial pneumonia]] - less inflammation.

Michael at 22:27, 7 April 2016

2016-04-07T22:27:01Z

← Older revision		Revision as of 22:27, 7 April 2016
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	\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles		\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[lymphoma]], follicular bronchitis/bronchiolitis, nodular lymphoid hyperplasia		\| LMDDx = [[lymphoma]], [[follicular bronchitis/bronchiolitis]], nodular lymphoid hyperplasia
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	DDx:		DDx:
	*[[Lymphoma]].		*[[Lymphoma]].
	*Follicular bronchitis/bronchiolitis.		*[[Follicular bronchitis/bronchiolitis]].
	*Nodular lymphoid hyperplasia.		*Nodular lymphoid hyperplasia.
	**This is determined in part by radiology; it has nodules radiographically.		**This is determined in part by radiology; it has nodules radiographically.

Michael: /* Microscopic */

2016-04-06T16:58:45Z

Microscopic

← Older revision		Revision as of 16:58, 6 April 2016
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	*Nodular lymphoid hyperplasia.		*Nodular lymphoid hyperplasia.
	**This is determined in part by radiology; it has nodules radiographically.		**This is determined in part by radiology; it has nodules radiographically.
			*[[Non-specific interstitial pneumonia]] - less inflammation.

	===Images===		===Images===

Michael: +infobox

2016-04-06T16:45:28Z

+infobox

← Older revision		Revision as of 16:45, 6 April 2016
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = small mature lymphocytes in the interstitium of the lung, plasma cells, +/-lymphoid follicles
			\| Subtypes =
			\| LMDDx = [[lymphoma]], follicular bronchitis/bronchiolitis, nodular lymphoid hyperplasia
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[lung]] - see ''[[diffuse lung diseases]]''
			\| Assdx = autoimmune disorders ([[rheumatoid arthritis]], [[pernicious anemia]], [[Sjoegren syndrome]]), viral infections ([[HIV]], [[EBV]], human T-cell leukemia virus (HTLV) type 1)
			\| Syndromes =
			\| Clinicalhx = dependent on underlying cause - see ''associated diagnoses''
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads = basilar predominance, increased interstitial markings
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Lymphocytic interstitial pneumonia''' (abbreviated '''LIP'''), also known as '''lymphoid interstitial pneumonia''' and '''lymphocytic interstitial pneumonitis''', is an uncommon [[diffuse lung disease]].		'''Lymphocytic interstitial pneumonia''' (abbreviated '''LIP'''), also known as '''lymphoid interstitial pneumonia''' and '''lymphocytic interstitial pneumonitis''', is an uncommon [[diffuse lung disease]].

Michael: /* General */

2014-12-09T06:37:17Z

General

← Older revision		Revision as of 06:37, 9 December 2014
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	==General==		==General==
	*Associated with autoimmune disorders ([[rheumatoid arthritis]], [[pernicious anemia]], [[Sjoegren syndrome]])<ref>URL: [http://emedicine.medscape.com/article/299643-overview http://emedicine.medscape.com/article/299643-overview]. Accessed on: 2 June 2010.</ref> and immunodeficiency.<ref name=pmid16088689>{{cite journal \|author=Nicholson AG \|title=Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung \|journal=Semin Respir Crit Care Med \|volume=22 \|issue=4 \|pages=409–22 \|year=2001 \|month=August \|pmid=16088689 \|doi=10.1055/s-2001-17384 \|url=}}</ref>		*Associated with autoimmune disorders ([[rheumatoid arthritis]], [[pernicious anemia]], [[Sjoegren syndrome]])<ref>URL: [http://emedicine.medscape.com/article/299643-overview http://emedicine.medscape.com/article/299643-overview]. Accessed on: 2 June 2010.</ref> and immunodeficiency.<ref name=pmid16088689>{{cite journal \|author=Nicholson AG \|title=Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung \|journal=Semin Respir Crit Care Med \|volume=22 \|issue=4 \|pages=409–22 \|year=2001 \|month=August \|pmid=16088689 \|doi=10.1055/s-2001-17384 \|url=}}</ref>
	*Associated with viral infections ([[HIV]], EBV, human T-cell leukemia virus (HTLV) type 1).		*Associated with viral infections ([[HIV]], [[EBV]], human T-cell leukemia virus (HTLV) type 1).
	**Considered an AIDS-defining diagnosis.<ref>{{Cite journal \| last1 = Turner \| first1 = BJ. \| last2 = Eppes \| first2 = S. \| last3 = McKee \| first3 = LJ. \| last4 = Cosler \| first4 = L. \| last5 = Markson \| first5 = LE. \| title = A population-based comparison of the clinical course of children and adults with AIDS. \| journal = AIDS \| volume = 9 \| issue = 1 \| pages = 65-72 \| month = Jan \| year = 1995 \| doi = \| PMID = 7893443 }}</ref>		**Considered an AIDS-defining diagnosis.<ref name=pmid7893443>{{Cite journal \| last1 = Turner \| first1 = BJ. \| last2 = Eppes \| first2 = S. \| last3 = McKee \| first3 = LJ. \| last4 = Cosler \| first4 = L. \| last5 = Markson \| first5 = LE. \| title = A population-based comparison of the clinical course of children and adults with AIDS. \| journal = AIDS \| volume = 9 \| issue = 1 \| pages = 65-72 \| month = Jan \| year = 1995 \| doi = \| PMID = 7893443 }}</ref>

	==Gross==		==Gross==

Michael: /* Microscopic */

2014-12-09T06:35:43Z

Microscopic

← Older revision		Revision as of 06:35, 9 December 2014
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	*No [[vasculitis]].		*No [[vasculitis]].
	*No [[necrosis]].		*No [[necrosis]].

	~~Images:~~
	*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].
	*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].

	DDx:		DDx:
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	*Nodular lymphoid hyperplasia.		*Nodular lymphoid hyperplasia.
	**This is determined in part by radiology; it has nodules radiographically.		**This is determined in part by radiology; it has nodules radiographically.

			===Images===
			www:
			*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].
			*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].

	==Stains==		==Stains==

Michael: split out

2014-12-09T06:33:36Z

split out

← Older revision		Revision as of 06:33, 9 December 2014
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	~~#redirect~~ [[~~Diffuse_lung_diseases#Lymphocytic_interstitial_pneumonia~~]]		'''Lymphocytic interstitial pneumonia''' (abbreviated '''LIP'''), also known as '''lymphoid interstitial pneumonia''' and '''lymphocytic interstitial pneumonitis''', is an uncommon [[diffuse lung disease]].

			==General==
			*Associated with autoimmune disorders ([[rheumatoid arthritis]], [[pernicious anemia]], [[Sjoegren syndrome]])<ref>URL: [http://emedicine.medscape.com/article/299643-overview http://emedicine.medscape.com/article/299643-overview]. Accessed on: 2 June 2010.</ref> and immunodeficiency.<ref name=pmid16088689>{{cite journal \|author=Nicholson AG \|title=Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung \|journal=Semin Respir Crit Care Med \|volume=22 \|issue=4 \|pages=409–22 \|year=2001 \|month=August \|pmid=16088689 \|doi=10.1055/s-2001-17384 \|url=}}</ref>
			*Associated with viral infections ([[HIV]], EBV, human T-cell leukemia virus (HTLV) type 1).
			**Considered an AIDS-defining diagnosis.<ref>{{Cite journal \| last1 = Turner \| first1 = BJ. \| last2 = Eppes \| first2 = S. \| last3 = McKee \| first3 = LJ. \| last4 = Cosler \| first4 = L. \| last5 = Markson \| first5 = LE. \| title = A population-based comparison of the clinical course of children and adults with AIDS. \| journal = AIDS \| volume = 9 \| issue = 1 \| pages = 65-72 \| month = Jan \| year = 1995 \| doi = \| PMID = 7893443 }}</ref>

			==Gross==
			*Location: basilar predominance.
			*Increased interstitial markings.

			==Microscopic==
			Features:<ref>URL: [http://emedicine.medscape.com/article/299643-diagnosis http://emedicine.medscape.com/article/299643-diagnosis]. Accessed on: 2 June 2010.</ref>
			*Small mature lymphocytes (usually B cells)<ref name=afip_vol2_265>AFIP atlas of nontumour pathology. 2002. Vo. 2. P.265. ISBN 1-881041-79-4.</ref> in the interstitium of the lung.
			*Plasma cells.
			*+/-Lymphoid follicles.

			Negatives:
			*No [[vasculitis]].
			*No [[necrosis]].

			Images:
			*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].
			*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].

			DDx:
			*[[Lymphoma]].
			*Follicular bronchitis/bronchiolitis.
			*Nodular lymphoid hyperplasia.
			**This is determined in part by radiology; it has nodules radiographically.

			==Stains==
			To exclude infection:<ref>URL: [http://path.upmc.edu/cases/case176/dx.html http://path.upmc.edu/cases/case176/dx.html]. Accessed on: 8 January 2012.</ref>
			*[[GMS stain]] -ve.
			*[[Ziehl-Neelsen stain]] -ve.

			==IHC==
			*May be done to exclude lymphoma.

			==See also==
			*[[Diffuse lung diseases]].

			==References==
			{{Reflist\|2}}

			[[Category:Diffuse lung diseases]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]