Keratinising squamous metaplasia of the urinary bladder - Revision history

Michael at 13:58, 25 May 2023

2023-05-25T13:58:59Z

← Older revision		Revision as of 13:58, 25 May 2023
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	Comment:		Comment:
	Regular follow-up is recommended.		Regular follow-up is recommended.[1,2]

			1. Urol Int 81 (3): 247-51. doi:10.1159/000151398. PMID 18931537.
			2. Urologia 87 (2): 97–100. doi:10.1177/0391560318810197. PMID 30509153.
	</pre>		</pre>

Michael at 13:57, 25 May 2023

2023-05-25T13:57:30Z

← Older revision		Revision as of 13:57, 25 May 2023
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	Treatment:		Treatment:
	*Follow-up is recommended.<ref name=pmid18931537/>		*Follow-up is recommended.<ref name=pmid18931537/><ref>{{cite journal \|authors=Benelli A, Varca V, Vaccaro C, Guzzo S, Nicola M, Onorati M, Gregori A, Di Nuovo F \|title=Keratinizing squamous metaplasia of the bladder: Our experience and current approaches \|journal=Urologia \|volume=87 \|issue=2 \|pages=97–100 \|date=May 2020 \|pmid=30509153 \|doi=10.1177/0391560318810197 \|url=}}</ref>

	Note:		Note:

Michael at 16:29, 11 February 2022

2022-02-11T16:29:03Z

← Older revision		Revision as of 16:29, 11 February 2022
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	}}		}}
	'''Keratinising squamous metaplasia of the urinary bladder''' is a rare benign change of the [[urinary bladder]] associated with an increased risk of [[malignancy]];<ref name=pmid12429156>{{Cite journal \| last1 = Khan \| first1 = MS. \| last2 = Thornhill \| first2 = JA. \| last3 = Gaffney \| first3 = E. \| last4 = Loftus \| first4 = B. \| last5 = Butler \| first5 = MR. \| title = Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience. \| journal = Eur Urol \| volume = 42 \| issue = 5 \| pages = 469-74 \| month = Nov \| year = 2002 \| doi = \| PMID = 12429156 }}</ref> however, it is not considered a pre-malignant condition.<ref name=pmid1379440>{{Cite journal \| last1 = Kvist \| first1 = E. \| last2 = Sjølin \| first2 = KE. \| last3 = Laursen \| first3 = H. \| last4 = Orntoft \| first4 = TF. \| last5 = Sturmer \| first5 = MA. \| title = Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients. \| journal = APMIS \| volume = 100 \| issue = 7 \| pages = 650-4 \| month = Jul \| year = 1992 \| doi = \| PMID = 1379440 }}</ref><ref name=pmid18931537>{{Cite journal \| last1 = Ahmad \| first1 = I. \| last2 = Barnetson \| first2 = RJ. \| last3 = Krishna \| first3 = NS. \| title = Keratinizing squamous metaplasia of the bladder: a review. \| journal = Urol Int \| volume = 81 \| issue = 3 \| pages = 247-51 \| month = \| year = 2008 \| doi = 10.1159/000151398 \| PMID = 18931537 }}</ref>		'''Keratinising squamous metaplasia of the urinary bladder''' is a rare benign change of the [[urinary bladder]] associated with an increased risk of [[malignancy]];<ref name=pmid12429156>{{Cite journal \| last1 = Khan \| first1 = MS. \| last2 = Thornhill \| first2 = JA. \| last3 = Gaffney \| first3 = E. \| last4 = Loftus \| first4 = B. \| last5 = Butler \| first5 = MR. \| title = Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience. \| journal = Eur Urol \| volume = 42 \| issue = 5 \| pages = 469-74 \| month = Nov \| year = 2002 \| doi = \| PMID = 12429156 }}</ref> however, it is not considered a pre-malignant condition.<ref name=pmid1379440>{{Cite journal \| last1 = Kvist \| first1 = E. \| last2 = Sjølin \| first2 = KE. \| last3 = Laursen \| first3 = H. \| last4 = Orntoft \| first4 = TF. \| last5 = Sturmer \| first5 = MA. \| title = Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients. \| journal = APMIS \| volume = 100 \| issue = 7 \| pages = 650-4 \| month = Jul \| year = 1992 \| doi = \| PMID = 1379440 }}</ref><ref name=pmid18931537>{{Cite journal \| last1 = Ahmad \| first1 = I. \| last2 = Barnetson \| first2 = RJ. \| last3 = Krishna \| first3 = NS. \| title = Keratinizing squamous metaplasia of the bladder: a review. \| journal = Urol Int \| volume = 81 \| issue = 3 \| pages = 247-51 \| month = \| year = 2008 \| doi = 10.1159/000151398 \| PMID = 18931537 }}</ref>

			''Urinary bladder with squamous metaplasia'' and ''squamous metaplasia of the urinary bladder'' redirect to this article.

	==General==		==General==

Michael: /* Microscopic */

2016-07-10T05:54:39Z

Microscopic

← Older revision		Revision as of 05:54, 10 July 2016
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	Features:		Features:
	*Squamous epithelium with hyperkeratosis or parakeratosis.		*Squamous epithelium with hyperkeratosis or parakeratosis.
			*Negative for significant [[nuclear atypia]].

	DDx:		DDx:

Michael at 05:54, 10 July 2016

2016-07-10T05:54:05Z

← Older revision		Revision as of 05:54, 10 July 2016
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Keratinizing squamous metaplasia of the bladder -- low mag.jpg
			\| Width =
			\| Caption = Keratinizing squamous metaplasia of the bladder. [[H&E stain]]. (WC/Nephron)
			\| Synonyms =
			\| Micro = squamous epithelium with hyperkeratosis or parakeratosis, negative for atypia
			\| Subtypes =
			\| LMDDx = [[squamous dysplasia]] of the metaplastic epithelium, [[squamous cell carcinoma of the urinary bladder]], metastatic [[squamous cell carcinoma]], [[urothelial carcinoma]] with squamous metaplasia or squamous differentiation
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[urinary bladder]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = usually males (males:females = 4:1)
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign, increased risk of malignancy
			\| Other =
			\| ClinDDx =
			\| Tx = clinical follow-up
			}}
	'''Keratinising squamous metaplasia of the urinary bladder''' is a rare benign change of the [[urinary bladder]] associated with an increased risk of [[malignancy]];<ref name=pmid12429156>{{Cite journal \| last1 = Khan \| first1 = MS. \| last2 = Thornhill \| first2 = JA. \| last3 = Gaffney \| first3 = E. \| last4 = Loftus \| first4 = B. \| last5 = Butler \| first5 = MR. \| title = Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience. \| journal = Eur Urol \| volume = 42 \| issue = 5 \| pages = 469-74 \| month = Nov \| year = 2002 \| doi = \| PMID = 12429156 }}</ref> however, it is not considered a pre-malignant condition.<ref name=pmid1379440>{{Cite journal \| last1 = Kvist \| first1 = E. \| last2 = Sjølin \| first2 = KE. \| last3 = Laursen \| first3 = H. \| last4 = Orntoft \| first4 = TF. \| last5 = Sturmer \| first5 = MA. \| title = Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients. \| journal = APMIS \| volume = 100 \| issue = 7 \| pages = 650-4 \| month = Jul \| year = 1992 \| doi = \| PMID = 1379440 }}</ref><ref name=pmid18931537>{{Cite journal \| last1 = Ahmad \| first1 = I. \| last2 = Barnetson \| first2 = RJ. \| last3 = Krishna \| first3 = NS. \| title = Keratinizing squamous metaplasia of the bladder: a review. \| journal = Urol Int \| volume = 81 \| issue = 3 \| pages = 247-51 \| month = \| year = 2008 \| doi = 10.1159/000151398 \| PMID = 18931537 }}</ref>		'''Keratinising squamous metaplasia of the urinary bladder''' is a rare benign change of the [[urinary bladder]] associated with an increased risk of [[malignancy]];<ref name=pmid12429156>{{Cite journal \| last1 = Khan \| first1 = MS. \| last2 = Thornhill \| first2 = JA. \| last3 = Gaffney \| first3 = E. \| last4 = Loftus \| first4 = B. \| last5 = Butler \| first5 = MR. \| title = Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience. \| journal = Eur Urol \| volume = 42 \| issue = 5 \| pages = 469-74 \| month = Nov \| year = 2002 \| doi = \| PMID = 12429156 }}</ref> however, it is not considered a pre-malignant condition.<ref name=pmid1379440>{{Cite journal \| last1 = Kvist \| first1 = E. \| last2 = Sjølin \| first2 = KE. \| last3 = Laursen \| first3 = H. \| last4 = Orntoft \| first4 = TF. \| last5 = Sturmer \| first5 = MA. \| title = Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients. \| journal = APMIS \| volume = 100 \| issue = 7 \| pages = 650-4 \| month = Jul \| year = 1992 \| doi = \| PMID = 1379440 }}</ref><ref name=pmid18931537>{{Cite journal \| last1 = Ahmad \| first1 = I. \| last2 = Barnetson \| first2 = RJ. \| last3 = Krishna \| first3 = NS. \| title = Keratinizing squamous metaplasia of the bladder: a review. \| journal = Urol Int \| volume = 81 \| issue = 3 \| pages = 247-51 \| month = \| year = 2008 \| doi = 10.1159/000151398 \| PMID = 18931537 }}</ref>

Michael: /* General */

2016-04-28T13:36:11Z

General

← Older revision		Revision as of 13:36, 28 April 2016
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	==General==		==General==
	*Rare.<ref name=pmid18931537/>		*Rare.<ref name=pmid18931537/> ‡
	**Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women.{{fact}}
	*Large age range (13-80 years).<ref name=pmid12429156/>		*Large age range (13-80 years).<ref name=pmid12429156/>
	*Predominantly males - almost 4:1 (27 males:7 females in one series<ref name=pmid12429156/>).		*Predominantly males - almost 4:1 (27 males:7 females in one series<ref name=pmid12429156/>).
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	Treatment:		Treatment:
	*Follow-up is recommended.<ref name=pmid18931537/>		*Follow-up is recommended.<ref name=pmid18931537/>

			Note:
			*‡ Non-keratinizing squamous metaplasia can be considered normal and is relatively common in the trigone region of the bladder in women.{{fact}}

	==Microscopic==		==Microscopic==

Michael: /* Microscopic */

2016-04-28T13:31:00Z

Microscopic

← Older revision		Revision as of 13:31, 28 April 2016
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	*[[Squamous cell carcinoma of the urinary bladder]].		*[[Squamous cell carcinoma of the urinary bladder]].
	*Metastatic [[squamous cell carcinoma]], e.g. [[squamous cell carcinoma of the uterine cervix]].		*Metastatic [[squamous cell carcinoma]], e.g. [[squamous cell carcinoma of the uterine cervix]].
	*[[Urothelial carcinoma]] with squamous metaplasia.		*[[Urothelial carcinoma]] with squamous metaplasia or squamous differentiation.

	==Sign out==		==Sign out==

Michael: /* Microscopic */

2016-04-28T13:30:28Z

Microscopic

← Older revision		Revision as of 13:30, 28 April 2016
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	*[[Squamous cell carcinoma of the urinary bladder]].		*[[Squamous cell carcinoma of the urinary bladder]].
	*Metastatic [[squamous cell carcinoma]], e.g. [[squamous cell carcinoma of the uterine cervix]].		*Metastatic [[squamous cell carcinoma]], e.g. [[squamous cell carcinoma of the uterine cervix]].
			*[[Urothelial carcinoma]] with squamous metaplasia.

	==Sign out==		==Sign out==

Michael: /* Sign out */

2016-04-28T13:29:46Z

Sign out

← Older revision		Revision as of 13:29, 28 April 2016
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	Comment:		Comment:
	~~Follow~~-up is recommended.		Regular follow-up is recommended.
	</pre>		</pre>

Michael: /* See also */

2016-04-28T13:11:03Z

← Older revision		Revision as of 13:11, 28 April 2016
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	==See also==		==See also==
	*[[Squamous cell carcinoma of the urinary bladder]].		*[[Squamous cell carcinoma of the urinary bladder]].
			*[[Squamous metaplasia]].

	==References==		==References==