Invasive cribriform carcinoma of the breast - Revision history

Michael: /* Microscopic */

2015-10-31T03:58:19Z

Microscopic

← Older revision		Revision as of 03:58, 31 October 2015
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid23412348/>		Features:<ref name=pmid23412348/>
	*Cribriform (or ~~seive~~-like) architecture.		*[[Cribriform]] (or sieve-like) architecture.
	*[[Desmoplastic stroma]].		*[[Desmoplastic stroma]].
	*+/-[[Tubular carcinoma of the breast\|Tubular]] component.		*+/-[[Tubular carcinoma of the breast\|Tubular]] component.

Michael at 03:44, 20 April 2015

2015-04-20T03:44:03Z

← Older revision		Revision as of 03:44, 20 April 2015
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	\| Micro = cribriform architecture, stromal desmoplasia, +/-tubular component		\| Micro = cribriform architecture, stromal desmoplasia, +/-tubular component
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[tubular carcinoma of the breast\|tubular carcinoma]], cribriform [[DCIS]], mixed tumour (e.g. ICC with [[invasive ductal carcinoma of the breast\|IDC]]		\| LMDDx = [[tubular carcinoma of the breast\|tubular carcinoma]], cribriform [[DCIS]], mixed tumour (e.g. ICC with [[invasive ductal carcinoma of the breast\|IDC]]), [[adenoid cystic carcinoma of the breast]]
	\| Stains =		\| Stains =
	\| IHC = ER +ve, PR +ve, HER2 -ve		\| IHC = ER +ve, PR +ve, HER2 -ve

Michael: /* Microscopic */

2015-04-20T03:43:43Z

Microscopic

← Older revision		Revision as of 03:43, 20 April 2015
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	==Microscopic==		==Microscopic==
	Features:		Features:<ref name=pmid23412348/>
	*Cribriform architecture.		*Cribriform (or seive-like) architecture.
	*[[Desmoplastic stroma]].		*[[Desmoplastic stroma]].
	*+/-[[Tubular carcinoma of the breast\|Tubular]] component.		*+/-[[Tubular carcinoma of the breast\|Tubular]] component.

	~~Note~~:		Notes:
	*Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal \| last1 = Zhang \| first1 = W. \| last2 = Zhang \| first2 = T. \| last3 = Lin \| first3 = Z. \| last4 = Zhang \| first4 = X. \| last5 = Liu \| first5 = F. \| last6 = Wang \| first6 = Y. \| last7 = Liu \| first7 = H. \| last8 = Yang \| first8 = Y. \| last9 = Niu \| first9 = Y. \| title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. \| journal = Int J Clin Exp Pathol \| volume = 6 \| issue = 3 \| pages = 445-57 \| month = \| year = 2013 \| doi = \| PMID = 23412348 }}</ref>		*Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal \| last1 = Zhang \| first1 = W. \| last2 = Zhang \| first2 = T. \| last3 = Lin \| first3 = Z. \| last4 = Zhang \| first4 = X. \| last5 = Liu \| first5 = F. \| last6 = Wang \| first6 = Y. \| last7 = Liu \| first7 = H. \| last8 = Yang \| first8 = Y. \| last9 = Niu \| first9 = Y. \| title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. \| journal = Int J Clin Exp Pathol \| volume = 6 \| issue = 3 \| pages = 445-57 \| month = \| year = 2013 \| doi = \| PMID = 23412348 \| PMC = 3563205}}</ref>
			*Low or intermediate Nottingham grade.

	DDx:		DDx:
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	*[[Tubular carcinoma of the breast]].		*[[Tubular carcinoma of the breast]].
	*[[Invasive ductal carcinoma of the breast]] with cribriform component.		*[[Invasive ductal carcinoma of the breast]] with cribriform component.
			*[[Adenoid cystic carcinoma of the breast]].

	===Images===		===Images===

Michael: fix

2015-04-20T03:39:26Z

fix

← Older revision		Revision as of 03:39, 20 April 2015
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	\| Micro = cribriform architecture, stromal desmoplasia, +/-tubular component		\| Micro = cribriform architecture, stromal desmoplasia, +/-tubular component
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[tubular carcinoma of the breast\|tubular carcinoma]], cribriform [[DCIS]], mixed tumour (e.g. ICC with [[invasive ductal carcinoma of the breast\|IDC)		\| LMDDx = [[tubular carcinoma of the breast\|tubular carcinoma]], cribriform [[DCIS]], mixed tumour (e.g. ICC with [[invasive ductal carcinoma of the breast\|IDC]]
	\| Stains =		\| Stains =
	\| IHC = ER +ve, PR +ve, HER2 -ve		\| IHC = ER +ve, PR +ve, HER2 -ve

Michael: +infobox

2015-04-20T03:38:55Z

+infobox

← Older revision		Revision as of 03:38, 20 April 2015
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Breast CribriformCarcinoma MP SNP.jpg
			\| Width =
			\| Caption = Invasive cribriform carcinoma of the breast. [[H&E stain]].
			\| Synonyms =
			\| Micro = cribriform architecture, stromal desmoplasia, +/-tubular component
			\| Subtypes =
			\| LMDDx = [[tubular carcinoma of the breast\|tubular carcinoma]], cribriform [[DCIS]], mixed tumour (e.g. ICC with [[invasive ductal carcinoma of the breast\|IDC)
			\| Stains =
			\| IHC = ER +ve, PR +ve, HER2 -ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[breast]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = very rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = good
			\| Other =
			\| ClinDDx =
			\| Tx = surgical
			}}
	'''Invasive cribriform carcinoma of the breast''' is a rare type of [[breast cancer]] with a favourable prognosis.<ref name=pmid25789036>{{Cite journal \| last1 = Cong \| first1 = Y. \| last2 = Qiao \| first2 = G. \| last3 = Zou \| first3 = H. \| last4 = Lin \| first4 = J. \| last5 = Wang \| first5 = X. \| last6 = Li \| first6 = X. \| last7 = Li \| first7 = Y. \| last8 = Zhu \| first8 = S. \| title = Invasive cribriform carcinoma of the breast: A report of nine cases and a review of the literature. \| journal = Oncol Lett \| volume = 9 \| issue = 4 \| pages = 1753-1758 \| month = Apr \| year = 2015 \| doi = 10.3892/ol.2015.2972 \| PMID = 25789036 }}</ref>		'''Invasive cribriform carcinoma of the breast''' is a rare type of [[breast cancer]] with a favourable prognosis.<ref name=pmid25789036>{{Cite journal \| last1 = Cong \| first1 = Y. \| last2 = Qiao \| first2 = G. \| last3 = Zou \| first3 = H. \| last4 = Lin \| first4 = J. \| last5 = Wang \| first5 = X. \| last6 = Li \| first6 = X. \| last7 = Li \| first7 = Y. \| last8 = Zhu \| first8 = S. \| title = Invasive cribriform carcinoma of the breast: A report of nine cases and a review of the literature. \| journal = Oncol Lett \| volume = 9 \| issue = 4 \| pages = 1753-1758 \| month = Apr \| year = 2015 \| doi = 10.3892/ol.2015.2972 \| PMID = 25789036 }}</ref>

Michael: tweak

2015-04-20T03:35:50Z

tweak

← Older revision		Revision as of 03:35, 20 April 2015
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	Features:		Features:
	*Cribriform architecture.		*Cribriform architecture.
			*[[Desmoplastic stroma]].
			*+/-[[Tubular carcinoma of the breast\|Tubular]] component.

	Note:		Note:
	*Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal \| last1 = Zhang \| first1 = W. \| last2 = Zhang \| first2 = T. \| last3 = Lin \| first3 = Z. \| last4 = Zhang \| first4 = X. \| last5 = Liu \| first5 = F. \| last6 = Wang \| first6 = Y. \| last7 = Liu \| first7 = H. \| last8 = Yang \| first8 = Y. \| last9 = Niu \| first9 = Y. \| title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. \| journal = Int J Clin Exp Pathol \| volume = 6 \| issue = 3 \| pages = 445-57 \| month = \| year = 2013 \| doi = \| PMID = 23412348 }}</ref>		*Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal \| last1 = Zhang \| first1 = W. \| last2 = Zhang \| first2 = T. \| last3 = Lin \| first3 = Z. \| last4 = Zhang \| first4 = X. \| last5 = Liu \| first5 = F. \| last6 = Wang \| first6 = Y. \| last7 = Liu \| first7 = H. \| last8 = Yang \| first8 = Y. \| last9 = Niu \| first9 = Y. \| title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. \| journal = Int J Clin Exp Pathol \| volume = 6 \| issue = 3 \| pages = 445-57 \| month = \| year = 2013 \| doi = \| PMID = 23412348 }}</ref>


	DDx:		DDx:
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	Image:Breast CribriformCarcinoma HP SNP.jpg\|Breast invasive cribriform carcinoma - high power. (SKB)		Image:Breast CribriformCarcinoma HP SNP.jpg\|Breast invasive cribriform carcinoma - high power. (SKB)
	</gallery>		</gallery>
			www:
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563205/figure/fig01/ ICC - panels A-C (nih.gov)].<ref name=pmid23412348/>

	==IHC==		==IHC==

Michael: expand

2015-04-20T03:25:56Z

expand

← Older revision		Revision as of 03:25, 20 April 2015
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	==General==		==General==
	*Rare.		*Rare ~ 0.6% of breast cancer in one series.<ref>{{Cite journal \| last1 = Stutz \| first1 = JA. \| last2 = Evans \| first2 = AJ. \| last3 = Pinder \| first3 = S. \| last4 = Ellis \| first4 = IO. \| last5 = Yeoman \| first5 = LJ. \| last6 = Wilson \| first6 = AR. \| last7 = Sibbering \| first7 = DM. \| title = The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham Breast Team. \| journal = Clin Radiol \| volume = 49 \| issue = 10 \| pages = 693-5 \| month = Oct \| year = 1994 \| doi = \| PMID = 7955831 }}</ref>
	*Low ~~Grade~~.		*Low grade.
	*Good prognosis if pure or associated with a tubular invasive component.<ref name=pmid6884999>{{Cite journal \| last1 = Page \| first1 = DL. \| last2 = Dixon \| first2 = JM. \| last3 = Anderson \| first3 = TJ. \| last4 = Lee \| first4 = D. \| last5 = Stewart \| first5 = HJ. \| title = Invasive cribriform carcinoma of the breast. \| journal = Histopathology \| volume = 7 \| issue = 4 \| pages = 525-36 \| month = Jul \| year = 1983 \| doi = \| PMID = 6884999 }}</ref>		*Good prognosis if pure or associated with a tubular invasive component.<ref name=pmid6884999>{{Cite journal \| last1 = Page \| first1 = DL. \| last2 = Dixon \| first2 = JM. \| last3 = Anderson \| first3 = TJ. \| last4 = Lee \| first4 = D. \| last5 = Stewart \| first5 = HJ. \| title = Invasive cribriform carcinoma of the breast. \| journal = Histopathology \| volume = 7 \| issue = 4 \| pages = 525-36 \| month = Jul \| year = 1983 \| doi = \| PMID = 6884999 }}</ref>

	==Microscopic==		==Microscopic==
			Features:
			*Cribriform architecture.

			Note:
			*Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal \| last1 = Zhang \| first1 = W. \| last2 = Zhang \| first2 = T. \| last3 = Lin \| first3 = Z. \| last4 = Zhang \| first4 = X. \| last5 = Liu \| first5 = F. \| last6 = Wang \| first6 = Y. \| last7 = Liu \| first7 = H. \| last8 = Yang \| first8 = Y. \| last9 = Niu \| first9 = Y. \| title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. \| journal = Int J Clin Exp Pathol \| volume = 6 \| issue = 3 \| pages = 445-57 \| month = \| year = 2013 \| doi = \| PMID = 23412348 }}</ref>

			DDx:
			*Cribriform [[DCIS]].
			*[[Tubular carcinoma of the breast]].
			*[[Invasive ductal carcinoma of the breast]] with cribriform component.

	===Images===		===Images===

Michael at 03:37, 17 April 2015

2015-04-17T03:37:49Z

← Older revision		Revision as of 03:37, 17 April 2015
Line 1:		Line 1:
	'''Invasive cribriform carcinoma of the breast''' is a rare type of [[breast cancer]] with a favourable prognosis.<ref>{{Cite journal \| last1 = Cong \| first1 = Y. \| last2 = Qiao \| first2 = G. \| last3 = Zou \| first3 = H. \| last4 = Lin \| first4 = J. \| last5 = Wang \| first5 = X. \| last6 = Li \| first6 = X. \| last7 = Li \| first7 = Y. \| last8 = Zhu \| first8 = S. \| title = Invasive cribriform carcinoma of the breast: A report of nine cases and a review of the literature. \| journal = Oncol Lett \| volume = 9 \| issue = 4 \| pages = 1753-1758 \| month = Apr \| year = 2015 \| doi = 10.3892/ol.2015.2972 \| PMID = 25789036 }}</ref>		'''Invasive cribriform carcinoma of the breast''' is a rare type of [[breast cancer]] with a favourable prognosis.<ref name=pmid25789036>{{Cite journal \| last1 = Cong \| first1 = Y. \| last2 = Qiao \| first2 = G. \| last3 = Zou \| first3 = H. \| last4 = Lin \| first4 = J. \| last5 = Wang \| first5 = X. \| last6 = Li \| first6 = X. \| last7 = Li \| first7 = Y. \| last8 = Zhu \| first8 = S. \| title = Invasive cribriform carcinoma of the breast: A report of nine cases and a review of the literature. \| journal = Oncol Lett \| volume = 9 \| issue = 4 \| pages = 1753-1758 \| month = Apr \| year = 2015 \| doi = 10.3892/ol.2015.2972 \| PMID = 25789036 }}</ref>

	==General==		==General==

Michael at 03:34, 17 April 2015

2015-04-17T03:34:46Z

← Older revision		Revision as of 03:34, 17 April 2015
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	Image:Breast CribriformCarcinoma HP SNP.jpg\|Breast invasive cribriform carcinoma - high power. (SKB)		Image:Breast CribriformCarcinoma HP SNP.jpg\|Breast invasive cribriform carcinoma - high power. (SKB)
	</gallery>		</gallery>

			==IHC==
			Features:<ref name=pmid25789036/>
			*ER +ve (9 +ve of 9 cases).
			*PR +ve (9 +ve of 9 cases).
			*HER2 -ve (0 +ve of 9 cases).

	==See also==		==See also==

Michael: /* Images */

2015-04-17T03:27:12Z

Images

← Older revision		Revision as of 03:27, 17 April 2015
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	===Images===		===Images===
	<gallery>		<gallery>
	Image:Breast CribriformCarcinoma LP SNP.jpg~~\|thumb~~\|Breast - ~~Invasive Cribriform Carcinoma - Low~~ power (SKB)		Image:Breast CribriformCarcinoma LP SNP.jpg\|Breast invasive cribriform carcinoma - low power. (SKB)
	Image:Breast CribriformCarcinoma MP SNP.jpg~~\|thumb~~\|Breast - ~~Invasive Cribriform Carcinoma - Medium~~ power (SKB)		Image:Breast CribriformCarcinoma MP SNP.jpg\|Breast invasive cribriform carcinoma - medium power. (SKB)
	Image:Breast CribriformCarcinoma HP SNP.jpg~~\|thumb~~\|Breast - ~~Invasive Cribriform Carcinoma - High~~ power (SKB)		Image:Breast CribriformCarcinoma HP SNP.jpg\|Breast invasive cribriform carcinoma - high power. (SKB)
	</gallery>		</gallery>