Intradermal nevus - Revision history

Michael: -

2016-08-26T17:38:49Z

← Older revision		Revision as of 17:38, 26 August 2016
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	==Sign out==		==Sign out==
			<pre>
			Skin, Left Alar Crease, Biopsy:
			- Benign intradermal nevus.
			</pre>

			===Block letters===
	<pre>		<pre>
	SKIN LESION, BACK, PUNCH BIOPSY:		SKIN LESION, BACK, PUNCH BIOPSY:

Michael at 01:15, 20 June 2014

2014-06-20T01:15:48Z

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	\| Micro = nests of melanocytes in dermis (only), melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement		\| Micro = nests of melanocytes in dermis (only), melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[compound nevus]], [[dysplastic nevus]], [[skin tag]]		\| LMDDx = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[compound nevus]], [[dysplastic nevus]], [[skin tag]], [[mastocytosis]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

Michael: /* Microscopic */

2014-06-20T01:15:27Z

Microscopic

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	*[[Compound nevus]].		*[[Compound nevus]].
	*[[Skin tag]].		*[[Skin tag]].
			*[[Mastocytosis]].

	===Images===		===Images===

Michael: /* Sign out */

2014-04-20T00:12:31Z

Sign out

← Older revision		Revision as of 00:12, 20 April 2014
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			<pre>
			SKIN LESION, BACK, PUNCH BIOPSY:
			- BENIGN INTRADERMAL NEVUS.
			</pre>

			====Adipocytes present====
			<pre>
			SKIN LESION, BACK, PUNCH BIOPSY:
			- BENIGN INTRADERMAL NEVUS WITH MATURE ADIPOCYTES.
			</pre>

			====Clinically suspicious====
			<pre>
			SKIN LESION, LEFT UPPER ARM, PUNCH BIOPSY:
			- BENIGN INTRADERMAL NEVUS, INCOMPLETELY EXCISED.

			COMMENT:
			HMB-45 marks very rare superficial cells. Ki-67 staining does not show apparent melanocyte
			staining. MITF marks the melanocytes and demonstrates maturation of the melanocytes with depth.
			</pre>

			===Micro===
			The sections show melanocytes in the dermis separated from the epidermis by a Grenz zone. The lesion is symmetrical in its architecture and pigment distribution. Superficially, melanocytes are in nests. Melanocytes mature with depth. No mitotic activity is appreciated.

			The lesion is completely excised in the plane of section.

			====IDN with congenital features====
			The sections show melanocytes in the dermis separated from the epidermis by a Grenz
			zone. The lesion is symmetrical in its architecture. Superficially, melanocytes are in
			nests. Melanocytes mature with depth and track along adnexal structures. No mitotic
			activity is appreciated. The lesion is incompletely excised in the plane of section.

	==See also==		==See also==

Michael at 00:10, 20 April 2014

2014-04-20T00:10:06Z

← Older revision		Revision as of 00:10, 20 April 2014
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	The ''intradermal nevus'' is in the large group '''[[common nevus]]'''. In common language, ''nevus'' is known as a ''mole''.		The ''intradermal nevus'' is in the large group '''[[common nevus]]'''. In common language, ''nevus'' is known as a ''mole''.

			In the oral cavity these are known as ''[[intramucosal melanocytic nevus\|intramucosal nevi]]''.

	==General==		==General==

Michael: split out

2014-04-20T00:08:25Z

split out

← Older revision		Revision as of 00:08, 20 April 2014
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	~~#redirect~~ [[~~Melanocytic~~ lesions#Intradermal melanocytic nevus]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Intradermal nevus -- intermed mag.jpg
			\| Width =
			\| Caption = Intradermal nevus. [[H&E stain]].
			\| Synonyms = intradermal melanocytic nevus
			\| Micro = nests of melanocytes in dermis (only), melanocytes "mature" with depth, usu. no mitoses (occ. superficial), no destruction of surrounding structures, no conspicuous nucleoli, no significant melanocyte enlargement
			\| Subtypes =
			\| LMDDx = [[malignant melanoma]] (nevoid), [[junctional nevus]], [[compound nevus]], [[dysplastic nevus]], [[skin tag]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = pigment skin lesion, usu. small, regular border, no irregularity in pigmentation
			\| Grossing =
			\| Site = [[skin]] - see ''[[melanocytic lesions]]'' and ''[[common nevus]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = very common
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx = pigmented skin lesions
			\| Tx = none required, may be excised for cosmetic reasons
			}}
			'''Intradermal nevus''' (abbreviated '''IDN'''), also '''intradermal melanocytic nevus''', is a common benign [[melanocytic lesion]].

			The ''intradermal nevus'' is in the large group '''[[common nevus]]'''. In common language, ''nevus'' is known as a ''mole''.

			==General==
			*Benign.
			*Common.
			*Think ''[[melanoma]]''.

			Clinical:
			*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large).

			==Microscopic==
			Features:
			*Symmetrical lesion.
			*"Matures" with depth.
			**Less cellular with depth.
			**Less nuclear atypia with depth.
			**Smaller cells with depth.
			**Smaller nests with depth.
			*Rare mitoses (superficial).
			**No deep mitoses.
			*No destruction of surrounding structures.
			*No nucleoli.
			*In the dermis only - '''key feature'''.
			*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal \| last1 = Eng \| first1 = W. \| last2 = Cohen \| first2 = PR. \| title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. \| journal = J Am Acad Dermatol \| volume = 39 \| issue = 5 Pt 1 \| pages = 704-11 \| month = Nov \| year = 1998 \| doi = \| PMID = 9810886 }}</ref>

			DDx:
			*[[Malignant melanoma]] (nevoid).
			*[[Dysplastic nevus]].
			*[[Junctional nevus]].
			*[[Compound nevus]].
			*[[Skin tag]].

			===Images===
			<gallery>
			Image: Intradermal nevus -- very low mag.jpg \| IDN - very low mag.
			Image: Intradermal nevus -- low mag.jpg \| IDN - low mag.
			Image: Intradermal nevus -- intermed mag.jpg \| IDN - intermed. mag.
			Image: Intradermal nevus -- high mag.jpg \| IDN - high mag.
			Image: Intradermal nevus -- very high mag.jpg \| IDN - very high mag.
			</gallery>

			==Sign out==


			==See also==
			*[[Melanocytic lesions]].

			==References==
			{{Reflist\|2}}

			[[Category:Diagnosis]]
			[[Category:Melanocytic lesions]]

Michael: redirect

2012-01-07T20:42:38Z

redirect

New page

#redirect [[Melanocytic lesions#Intradermal melanocytic nevus]]