Hypersensitivity pneumonitis - Revision history

Michael: /* Microscopic */

2015-03-17T19:06:49Z

Microscopic

← Older revision		Revision as of 19:06, 17 March 2015
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	DDx:		DDx:
	*[[Usual interstitial pneumonia]].		*[[Usual interstitial pneumonia]].
			*[[Nonspecific interstitial pneumonia]].

	===Images===		===Images===

Michael at 19:05, 17 March 2015

2015-03-17T19:05:23Z

← Older revision		Revision as of 19:05, 17 March 2015
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	\| coal dust		\| coal dust
	\|}		\|}

			==Gross==
			*Peripheral or peribronchiolar.<ref name=pmid16434894>{{Cite journal \| last1 = Churg \| first1 = A. \| last2 = Muller \| first2 = NL. \| last3 = Flint \| first3 = J. \| last4 = Wright \| first4 = JL. \| title = Chronic hypersensitivity pneumonitis. \| journal = Am J Surg Pathol \| volume = 30 \| issue = 2 \| pages = 201-8 \| month = Feb \| year = 2006 \| doi = \| PMID = 16434894 }}</ref>
			**Not large airways.

	==Microscopic==		==Microscopic==

Michael at 13:31, 15 July 2014

2014-07-15T13:31:56Z

← Older revision		Revision as of 13:31, 15 July 2014
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	\| Tx = eliminate allergen exposure		\| Tx = eliminate allergen exposure
	}}		}}
	'''~~Hypersensitivity_pneumonitis~~''', abbreviated '''[[HP]]''', is a [[diffuse lung diseases]] caused by an allergen.		'''Hypersensitivity pneumonitis''', abbreviated '''[[HP]]''', is a [[diffuse lung diseases]] caused by an allergen.

	It is also known as '''extrinsic allergic alveolitis''', abbreviated '''EAA'''.		It is also known as '''extrinsic allergic alveolitis''', abbreviated '''EAA'''.

Michael: /* See also */

2014-05-30T03:22:50Z

Michael: +table

2014-05-30T03:13:38Z

+table

← Older revision		Revision as of 03:13, 30 May 2014
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	*An immune complex-mediated [[hypersensitivity]]<ref name=pmid8279154>{{Cite journal \| last1 = Kaltreider \| first1 = HB. \| title = Hypersensitivity pneumonitis. \| journal = West J Med \| volume = 159 \| issue = 5 \| pages = 570-8 \| month = Nov \| year = 1993 \| doi = \| PMID = 8279154 \| url = http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/8279154/?tool=pubmed }}</ref> (Gell-Coombs classification type III).		*An immune complex-mediated [[hypersensitivity]]<ref name=pmid8279154>{{Cite journal \| last1 = Kaltreider \| first1 = HB. \| title = Hypersensitivity pneumonitis. \| journal = West J Med \| volume = 159 \| issue = 5 \| pages = 570-8 \| month = Nov \| year = 1993 \| doi = \| PMID = 8279154 \| url = http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/8279154/?tool=pubmed }}</ref> (Gell-Coombs classification type III).
	**If chronic, may develop into a cell-mediated hypersensitivity (Gell-Coombs classification type IV).<ref>URL: [http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/pufrm.html http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/pufrm.html]. Accessed on: 4 December 2011.</ref>		**If chronic, may develop into a cell-mediated hypersensitivity (Gell-Coombs classification type IV).<ref>URL: [http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/pufrm.html http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/pufrm.html]. Accessed on: 4 December 2011.</ref>

			===Specific diseases/etiology===
			Selected causes of hypersensitivity pneumonitis:<ref name=pmid21978856>{{cite journal \|author=Zacharisen MC, Fink JN \|title=Hypersensitivity pneumonitis and related conditions in the work environment \|journal=Immunol Allergy Clin North Am \|volume=31 \|issue=4 \|pages=769–86, vii \|year=2011 \|month=November \|pmid=21978856 \|doi=10.1016/j.iac.2011.07.004 \|url=}}</ref>
			{\| class="wikitable sortable"
			! Disease
			! Cause
			\|-
			\| Silicosis
			\| silica exposure
			\|-
			\| \|[[Asbestosis]]
			\| asbestos
			\|-
			\| Flavour-worker's lung (popcorn lung)
			\| diacetyl - used for butter flavour<ref name=pmid21618944>{{cite journal \|author=Egilman DS, Schilling JH, Menendez L \|title=A proposal for a safe exposure level for diacetyl \|journal=Int J Occup Environ Health \|volume=17 \|issue=2 \|pages=122–34 \|year=2011 \|pmid=21618944 \|doi= \|url=}}</ref>
			\|-
			\| [[Talcosis]]
			\|
			\|-
			\| Sick building syndrome
			\| volatile organic compounds, smoke, dampness
			\|-
			\| Berylliosis
			\| beryllium
			\|-
			\| Coal worker’s pneumoconiosis
			\| coal dust
			\|}

	==Microscopic==		==Microscopic==

Michael at 02:53, 30 May 2014

2014-05-30T02:53:40Z

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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Hypersensitivity pneumonitis intermed mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Hypersensitivity pneumonitis. Trichrome stain.
	\| Synonyms = extrinsic allergic alveolitis		\| Synonyms = extrinsic allergic alveolitis
	\| Micro = centrilobular prominence of lesions, [[granulomata]], chronic interstitial inflammation consisting primarily of lymphocytes, interstitial fibrosis, air space involvement (alveolitis)		\| Micro = centrilobular prominence of lesions, [[granulomata]], chronic interstitial inflammation consisting primarily of lymphocytes, interstitial fibrosis, air space involvement (alveolitis)

Michael: split out

2014-05-30T02:52:44Z

split out

← Older revision		Revision as of 02:52, 30 May 2014
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	~~#redirect~~ [[~~Diffuse_lung_diseases#~~Hypersensitivity_pneumonitis]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms = extrinsic allergic alveolitis
			\| Micro = centrilobular prominence of lesions, [[granulomata]], chronic interstitial inflammation consisting primarily of lymphocytes, interstitial fibrosis, air space involvement (alveolitis)
			\| Subtypes =
			\| LMDDx = [[usual interstitial pneumonia]], [[asbestosis]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[lung]] - see ''[[diffuse lung diseases]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = allergen exposure
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads = upper lung predominant
			\| Endoscopy =
			\| Prognosis = usu. good if allergen exposure eliminated
			\| Other =
			\| ClinDDx = other [[diffuse lung diseases]], esp. [[idiopathic pulmonary fibrosis]]
			\| Tx = eliminate allergen exposure
			}}
			'''Hypersensitivity_pneumonitis''', abbreviated '''[[HP]]''', is a [[diffuse lung diseases]] caused by an allergen.

			It is also known as '''extrinsic allergic alveolitis''', abbreviated '''EAA'''.

			==General==
			*Exposure to stuffs... e.g. moldy hay - ''Farmer's lung'', atypical mycobacteria - ''hot tub lung''.
			*Upper lung predominant disease.
			**Mnemonic ''FASSTEN'' - upper lung field: [[Farmer's lung]], [[Ankylosing spondylitis]], [[Sarcoidosis]], [[Silicosis]], [[Tuberculosis]] (miliary), [[Eosinophilic granuloma]], [[Neurofibromatosis]].
			*An immune complex-mediated [[hypersensitivity]]<ref name=pmid8279154>{{Cite journal \| last1 = Kaltreider \| first1 = HB. \| title = Hypersensitivity pneumonitis. \| journal = West J Med \| volume = 159 \| issue = 5 \| pages = 570-8 \| month = Nov \| year = 1993 \| doi = \| PMID = 8279154 \| url = http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/8279154/?tool=pubmed }}</ref> (Gell-Coombs classification type III).
			**If chronic, may develop into a cell-mediated hypersensitivity (Gell-Coombs classification type IV).<ref>URL: [http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/pufrm.html http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/pufrm.html]. Accessed on: 4 December 2011.</ref>

			==Microscopic==
			Features:
			* Lesions have centrilobular prominence - '''important feature'''. <ref name=pmid16061708/>
			** Allergens enter lung through airway which has a centrilobular location.
			* [[Granulomata]] (not typically seen in UIP) - '''important feature'''.<ref name=pmid16061708>{{Cite journal \| last1 = Ohtani \| first1 = Y. \| last2 = Saiki \| first2 = S. \| last3 = Kitaichi \| first3 = M. \| last4 = Usui \| first4 = Y. \| last5 = Inase \| first5 = N. \| last6 = Costabel \| first6 = U. \| last7 = Yoshizawa \| first7 = Y. \| title = Chronic bird fancier's lung: histopathological and clinical correlation. An application of the 2002 ATS/ERS consensus classification of the idiopathic interstitial pneumonias. \| journal = Thorax \| volume = 60 \| issue = 8 \| pages = 665-71 \| month = Aug \| year = 2005 \| doi = 10.1136/thx.2004.027326 \| PMID = 16061708 }}</ref>
			* Chronic interstitial inflammation consisting primarily of lymphocytes.
			* Interstitial fibrosis.
			* Air space involvement (alveolitis).

			DDx:
			*[[Usual interstitial pneumonia]].

			===Images===
			<gallery>
			Image:Hypersensitivity_pneumonitis_low_mag.jpg \| Hypersensitivity pneumonitis - low mag. (WC/Nephron)
			Image:Hypersensitivity_pneumonitis_intermed_mag.jpg \| Hypersensitivity pneumonitis - intermed. mag. (WC/Nephron)
			Image:Hypersensitivity_pneumonitis_high_mag.jpg \| Hypersensitivity pneumonitis - high mag. (WC/Nephron)
			</gallery>

			==See also==
			*[[Diffuse lung diseases]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Diffuse lung diseases]]

Michael: redirect +cat.

2011-11-04T15:05:35Z

redirect +cat.

← Older revision		Revision as of 15:05, 4 November 2011
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	#redirect [[~~Medical_lung_diseases~~#Hypersensitivity_pneumonitis]]		#redirect [[Diffuse_lung_diseases#Hypersensitivity_pneumonitis]]

			[[Category:Diagnosis]]

Michael: redirect for now

2011-08-15T17:05:57Z

redirect for now

New page

#redirect [[Medical_lung_diseases#Hypersensitivity_pneumonitis]]

← Older revision		Revision as of 03:22, 30 May 2014
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	==See also==		==See also==
	*[[Diffuse lung diseases]].		*[[Diffuse lung diseases]].
			*[[Pneumoconioses]].

	==References==		==References==