Hyperplastic polyp with perineuromatous stroma - Revision history

Michael at 21:15, 20 April 2021

2021-04-20T21:15:55Z

← Older revision		Revision as of 21:15, 20 April 2021
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	'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign [[colorectal polyp]].		'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign [[colorectal polyp]].

	It may be referred to as '''[[perineurioma]]''' and '''fibroblastic polyp'''.<ref name=pmid18520438>{{cite journal \|~~vauthors~~=Groisman GM, Polak-Charcon S \|title=Fibroblastic polyp of the colon and colonic perineurioma: 2 names for a single entity? \|journal=Am J Surg Pathol \|volume=32 \|issue=7 \|pages=1088–94 \|date=July 2008 \|pmid=18520438 \|doi=10.1097/PAS.0b013e318160df3f \|url=}}</ref>		It may be referred to as '''[[perineurioma]]''' and '''fibroblastic polyp'''.<ref name=pmid18520438>{{cite journal \|authors=Groisman GM, Polak-Charcon S \|title=Fibroblastic polyp of the colon and colonic perineurioma: 2 names for a single entity? \|journal=Am J Surg Pathol \|volume=32 \|issue=7 \|pages=1088–94 \|date=July 2008 \|pmid=18520438 \|doi=10.1097/PAS.0b013e318160df3f \|url=}}</ref>

	==General==		==General==

Michael: /* IHC */

2021-04-20T21:15:37Z

IHC

← Older revision		Revision as of 21:15, 20 April 2021
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	==IHC==		==IHC==
	Features:<ref name=pmid15104300>{{cite journal \|~~vauthors~~=Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D \|title=Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study \|journal=Am J Surg Pathol \|volume=28 \|issue=3 \|pages=374–8 \|date=March 2004 \|pmid=15104300 \|doi=10.1097/00000478-200403000-00010 \|url=}}</ref>		Features:<ref name=pmid15104300>{{cite journal \|authors=Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D \|title=Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study \|journal=Am J Surg Pathol \|volume=28 \|issue=3 \|pages=374–8 \|date=March 2004 \|pmid=15104300 \|doi=10.1097/00000478-200403000-00010 \|url=}}</ref>
	*Vimentin +ve.		*Vimentin +ve.
	*SMA -ve.		*SMA -ve.

Michael: /* IHC */

2021-04-20T21:14:52Z

IHC

← Older revision		Revision as of 21:14, 20 April 2021
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	*S-100 -ve		*S-100 -ve
	*EMA -ve.		*EMA -ve.

			==Sign out==
			<pre>
			Polyp, Colon at 35 cm, Polypectomy or Biopsy:
			- Hyperplastic polyp with perineuromatous stroma.
			</pre>

			===Micro===
			The sections show a polypoid fragment of colonic-type serrated epithelium with small round glands at the deep aspect. Fibroblastic/perineuromatous type stroma is present and NSE NEGATIVE, S100 NEGATIVE and desmin NEGATIVE. The tissue is NEGATIVE for atypia and NEGATIVE for apparent proliferative activity.

	==See also==		==See also==

Michael: /* See also */ more

2021-04-20T21:06:03Z

Michael at 21:03, 20 April 2021

2021-04-20T21:03:06Z

← Older revision		Revision as of 21:03, 20 April 2021
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	\| Tx =		\| Tx =
	}}		}}
	'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign colorectal polyp.		'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign [[colorectal polyp]].

			It may be referred to as '''[[perineurioma]]''' and '''fibroblastic polyp'''.<ref name=pmid18520438>{{cite journal \|vauthors=Groisman GM, Polak-Charcon S \|title=Fibroblastic polyp of the colon and colonic perineurioma: 2 names for a single entity? \|journal=Am J Surg Pathol \|volume=32 \|issue=7 \|pages=1088–94 \|date=July 2008 \|pmid=18520438 \|doi=10.1097/PAS.0b013e318160df3f \|url=}}</ref>

	==General==		==General==

Michael: /* See also */

2018-08-29T14:18:49Z

Michael at 00:54, 29 October 2015

2015-10-29T00:54:12Z

← Older revision		Revision as of 00:54, 29 October 2015
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Hyperplastic polyp with perineuromatous stroma - alt -- intermed mag.jpg
			\| Width =
			\| Caption = Hyperplastic polyp with perineuromatous stroma. [[H&E stain]].
			\| Synonyms = benign serrated colorectal fibroblastic polyps/intramucosal perineurioma, hybrid hyperplastic polyp/mucosal perineurioma
			\| Micro = serrated epithelial cells (at the surface), perineuromatous stroma
			\| Subtypes =
			\| LMDDx = [[colonic ganglioneuroma]], [[hyperplastic polyp]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[colon]] and [[rectum]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy = polyp
			\| Prognosis = benign
			\| Other =
			\| ClinDDx = other types of [[colorectal polyps]]
			\| Tx =
			}}
	'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign colorectal polyp.		'''Hyperplastic polyp with perineuromatous stroma''', also known as '''benign serrated colorectal fibroblastic polyps/intramucosal perineurioma''' and '''hybrid hyperplastic polyp/mucosal perineurioma''', is a benign colorectal polyp.

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	Image: Hyperplastic polyp with perineuromatous stroma -- very low mag.jpg \| HP with PNS - very low mag.		Image: Hyperplastic polyp with perineuromatous stroma -- very low mag.jpg \| HP with PNS - very low mag.
	Image: Hyperplastic polyp with perineuromatous stroma -- low mag.jpg \| HP with PNS - low mag.		Image: Hyperplastic polyp with perineuromatous stroma -- low mag.jpg \| HP with PNS - low mag.
	Image: Hyperplastic polyp with perineuromatous stroma -- intermed mag.jpg \| HP with PNS - intermed. ~~low~~ mag.		Image: Hyperplastic polyp with perineuromatous stroma -- intermed mag.jpg \| HP with PNS - intermed. mag.
	Image: Hyperplastic polyp with perineuromatous stroma - alt -- intermed mag.jpg \| HP with PNS - intermed. ~~low~~ mag.		Image: Hyperplastic polyp with perineuromatous stroma - alt -- intermed mag.jpg \| HP with PNS - intermed. mag.
	Image: Hyperplastic polyp with perineuromatous stroma -- high mag.jpg \| HP with PNS - high mag.		Image: Hyperplastic polyp with perineuromatous stroma -- high mag.jpg \| HP with PNS - high mag.
	Image: Hyperplastic polyp with perineuromatous stroma - alt -- high mag.jpg \| HP with PNS - high mag.		Image: Hyperplastic polyp with perineuromatous stroma - alt -- high mag.jpg \| HP with PNS - high mag.

Michael: /* Microscopic */

2015-10-29T00:38:56Z

Microscopic

← Older revision		Revision as of 00:38, 29 October 2015
Line 13:		Line 13:
	DDx:		DDx:
	*[[Hyperplastic polyp]].		*[[Hyperplastic polyp]].
	*[[~~Ganglioneuroma~~]].		*[[Colonic ganglioneuroma]].

	===Images===		===Images===

Michael: /* Microscopic */

2015-10-29T00:36:36Z

Microscopic

← Older revision		Revision as of 00:36, 29 October 2015
Line 13:		Line 13:
	DDx:		DDx:
	*[[Hyperplastic polyp]].		*[[Hyperplastic polyp]].
			*[[Ganglioneuroma]].

	===Images===		===Images===

Michael at 00:33, 29 October 2015

2015-10-29T00:33:29Z

← Older revision		Revision as of 00:33, 29 October 2015
Line 13:		Line 13:
	DDx:		DDx:
	*[[Hyperplastic polyp]].		*[[Hyperplastic polyp]].

			===Images===
			<gallery>
			Image: Hyperplastic polyp with perineuromatous stroma -- very low mag.jpg \| HP with PNS - very low mag.
			Image: Hyperplastic polyp with perineuromatous stroma -- low mag.jpg \| HP with PNS - low mag.
			Image: Hyperplastic polyp with perineuromatous stroma -- intermed mag.jpg \| HP with PNS - intermed. low mag.
			Image: Hyperplastic polyp with perineuromatous stroma - alt -- intermed mag.jpg \| HP with PNS - intermed. low mag.
			Image: Hyperplastic polyp with perineuromatous stroma -- high mag.jpg \| HP with PNS - high mag.
			Image: Hyperplastic polyp with perineuromatous stroma - alt -- high mag.jpg \| HP with PNS - high mag.
			Image: Hyperplastic polyp with perineuromatous stroma -- very high mag.jpg \| HP with PNS - very high mag.
			</gallery>

	==See also==		==See also==

← Older revision		Revision as of 14:18, 29 August 2018
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	*[[Hyperplastic polyp]].		*[[Hyperplastic polyp]].
	*[[Gastrointestinal polyps]].		*[[Gastrointestinal polyps]].
			*[[Perineurioma]].

	==References==		==References==

← Older revision		Revision as of 21:06, 20 April 2021
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	Image: Hyperplastic polyp with perineuromatous stroma -- very high mag.jpg \| HP with PNS - very high mag.		Image: Hyperplastic polyp with perineuromatous stroma -- very high mag.jpg \| HP with PNS - very high mag.
	</gallery>		</gallery>

			==IHC==
			Features:<ref name=pmid15104300>{{cite journal \|vauthors=Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D \|title=Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study \|journal=Am J Surg Pathol \|volume=28 \|issue=3 \|pages=374–8 \|date=March 2004 \|pmid=15104300 \|doi=10.1097/00000478-200403000-00010 \|url=}}</ref>
			*Vimentin +ve.
			*SMA -ve.
			*Desmin -ve.
			*CD117 -ve.
			*S-100 -ve
			*EMA -ve.

	==See also==		==See also==