Hepatic sarcoidosis - Revision history

Michael: /* Microscopic */

2021-09-30T21:02:26Z

Microscopic

← Older revision		Revision as of 21:02, 30 September 2021
Line 11:		Line 11:
	DDx:		DDx:
	*[[Drug induced liver disease]].		*[[Drug induced liver disease]].
	*[[Primary biliary ~~cirrhosis~~]].		*[[Primary biliary cholangitis]].
	*Infection.		*Infection.
	**[[Tuberculosis]].		**[[Tuberculosis]].

Mitchell: /* Microscopic */ added a case

2016-09-21T22:25:47Z

Microscopic: added a case

← Older revision		Revision as of 22:25, 21 September 2016
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	**[[Tuberculosis]].		**[[Tuberculosis]].
	**[[Histoplasmosis]].		**[[Histoplasmosis]].

			{\|
			[[File:1 sarcoid 1 680x512px.tif\| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
			[[File:2 sarcoid 1 680x512px.tif\| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
			<br>
			[[File:3 sarcoid 1 680x512px.tif\| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
			[[File:4 sarcoid 1 680x512px.tif\| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
			<br>
			[[File:5 sarcoid 1 680x512px.tif\| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
			[[File:6 sarcoid 1 680x512px.tif\| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
			\|}
			Hepatic sarcoidosis in a patient with previously known sarcoidosis. At low power markedly distorted parenchyma is highlighted by seeing the minor component of unaffected cores [parallel to double headed arrowsD] (Row 1 Left 20X). All but the lower left part is affected by a large granuloma strewing Touton body giant cells [arrows] (Row 1 Right 100X). PAS without diastase shows granulomas separated by a small column of hepatocytes (Row 2 Left 200X). Trichrome here shows the extensive fibrosis associated with the granulomatous inflammation in this case(Row 2 Right 200X). Trichrome here demonstrates a utility in picking up giant cells [arrows], whose cytoplasm often stains differently than the surrounding fibrosis (Row 3 Left 200X). As shown by this trichrome stained image, most triads showed fibrosis; none showed involvement by granuloma or increased chronic stromal inflammation (Row 3 Right 200X).

	==See also==		==See also==

Michael: create

2016-06-10T13:29:03Z

create

New page

'''Hepatic sarcoidosis''', also '''liver sarcoidosis''', is involvement of the [[liver]] by the disease [[sarcoidosis]].

==General==
*Approximately 12% of individuals with sarcoidosis have liver involvement.<ref name=pmid17081481>{{Cite journal | last1 = Ayyala | first1 = US. | last2 = Padilla | first2 = ML. | title = Diagnosis and treatment of hepatic sarcoidosis. | journal = Curr Treat Options Gastroenterol | volume = 9 | issue = 6 | pages = 475-83 | month = | year = 2006 | doi = | PMID = 17081481 }}
</ref>

==Microscopic==
Features:
*Well-formed non-necrotizing [[granulomas]].

DDx:
*[[Drug induced liver disease]].
*[[Primary biliary cirrhosis]].
*Infection.
**[[Tuberculosis]].
**[[Histoplasmosis]].

==See also==
*[[Medical liver disease]].

==References==
{{Reflist|1}}

[[Category:Gastrointestinal pathology]]
[[Category:Diagnosis]]