Hamartoma - Revision history

Michael at 02:48, 30 November 2014

2014-11-30T02:48:57Z

← Older revision		Revision as of 02:48, 30 November 2014
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			[[Image:Pulmonary hamartoma - low mag.jpg\|thumb\|right\|250px\|Micrograph of a [[pulmonary hamartoma]]. [[H&E stain]].]]
	A '''hamartoma''' is a:<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=84157 http://www.medterms.com/script/main/art.asp?articlekey=84157]. Accessed on: 22 November 2010.</ref><ref name=Ref_PCPBoD8_147>{{Ref PCPBoD8\|147}}</ref>		A '''hamartoma''' is a:<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=84157 http://www.medterms.com/script/main/art.asp?articlekey=84157]. Accessed on: 22 November 2010.</ref><ref name=Ref_PCPBoD8_147>{{Ref PCPBoD8\|147}}</ref>
	#Disorganized (non-neoplastic) growth (that may mimic a true neoplasm).		#Disorganized (non-neoplastic) growth (that may mimic a true neoplasm).

Michael: /* Site specific */

2014-06-22T02:46:32Z

Site specific

← Older revision		Revision as of 02:46, 22 June 2014
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	*[[Neurocristic hamartoma]].		*[[Neurocristic hamartoma]].
	*[[Peutz-Jeghers polyp]].		*[[Peutz-Jeghers polyp]].
			*[[Fibrous hamartoma of infancy]].

	==See also==		==See also==

Michael: /* Note 2 */ rm commentary

2013-11-07T02:00:00Z

Note 2: rm commentary

← Older revision		Revision as of 02:00, 7 November 2013
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	#Architecturally disorganized tissue that appears to be native to the site.		#Architecturally disorganized tissue that appears to be native to the site.
	#No significant growth (vis-à-vis the surrounding tissue).		#No significant growth (vis-à-vis the surrounding tissue).

	~~VL opinion: ''hamartoma'' (and ''choristoma'') are useless descriptors and the terms should just be done away with.~~

	==Site specific==		==Site specific==

Michael: /* Site specific */

2013-11-06T13:39:26Z

Site specific

← Older revision		Revision as of 13:39, 6 November 2013
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	*[[Splenic hamartoma]].		*[[Splenic hamartoma]].
	*[[Neurocristic hamartoma]].		*[[Neurocristic hamartoma]].
			*[[Peutz-Jeghers polyp]].

	==See also==		==See also==

Michael: /* See also */ +odontoma

2012-05-29T16:02:33Z

Michael: /* Site specific */ +neurocristic h.

2011-12-11T01:05:43Z

Site specific: +neurocristic h.

← Older revision		Revision as of 01:05, 11 December 2011
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	*[[Pulmonary hamartoma]].		*[[Pulmonary hamartoma]].
	*[[Splenic hamartoma]].		*[[Splenic hamartoma]].
			*[[Neurocristic hamartoma]].

	==See also==		==See also==

Michael: redirect

2011-10-04T05:17:42Z

redirect

← Older revision		Revision as of 05:17, 4 October 2011
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	==Site specific==		==Site specific==
			*[[Mammary hamartoma]].
	*[[Pulmonary hamartoma]].		*[[Pulmonary hamartoma]].
	*[[Splenic hamartoma]].		*[[Splenic hamartoma]].

Michael at 03:49, 8 September 2011

2011-09-08T03:49:17Z

← Older revision		Revision as of 03:49, 8 September 2011
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	===Note 1===		===Note 1===
	#If #2 does ''not'' apply it is a ''[[choristoma]]''.		#If #2 does ''not'' apply it is a '''choristoma'''.
	#"Disorganized" in #1 separates it from:		#"Disorganized" in #1 separates it from:
	#*Hypertrophy and hyperplasia - which may be physiologic processes.		#*Hypertrophy and hyperplasia - which may be physiologic processes.

Michael: more

2011-09-08T03:46:05Z

← Older revision		Revision as of 03:46, 8 September 2011
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	A '''hamartoma''' is a:<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=84157 http://www.medterms.com/script/main/art.asp?articlekey=84157]. Accessed on: 22 November 2010.</ref>		A '''hamartoma''' is a:<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=84157 http://www.medterms.com/script/main/art.asp?articlekey=84157]. Accessed on: 22 November 2010.</ref><ref name=Ref_PCPBoD8_147>{{Ref PCPBoD8\|147}}</ref>
	#Disorganized non-neoplastic growth (that may mimic a true neoplasm).		#Disorganized (non-neoplastic) growth (that may mimic a true neoplasm).
			#*May be clonal.
			#*May have recurrent genetic [[translocations]].
	#Composed of tissue of the region within it is found.		#Composed of tissue of the region within it is found.

	~~Notes:~~		===Note 1===
	*If #2 does ''not'' apply it is a ''~~choristomas~~''.		#If #2 does ''not'' apply it is a ''[[choristoma]]''.
	*"Disorganized" in #1 separates it from ~~hypertrophy~~ and hyperplasia ~~(quasi~~-physiologic processes).		#"Disorganized" in #1 separates it from:
			#*Hypertrophy and hyperplasia - which may be physiologic processes.
			#The '''key differences''' between cancer and hamartoma are the ability of cancer to:
			#*Invade/destroy surrounding tissue.
			#*Metastasize.
			#Considered clinically, ''growth'' is the difference between a ''benign tumour'' (measurable growth rate) and a ''hamartoma'' (no growth vis-à-vis the surrounding tissue).
			#Hamartomas often consist of:
			#*Multiple cell types, e.g. [[Peutz-Jeghers polyps]] consist of normal submucosal elements.
			#*Have a well-circumscribed border.

			===Note 2===
			There is much confusion in this area as:
			*''Clonality'' is usually considered a characteristic of neoplasms.
			*The line between ''benign tumour'' and ''hamartoma'' is thin, if one considers that a hamartoma can be clonal and some benign tumours have a slow growth rate.
			*If one considers ''choristoma'' (hamartoma's cousin), the line between ''benign tumour'' (e.g. teratoma/dermoid cyst) and ''choristoma'' is thin.

			A more useful definition of ''hamartoma'' might be:
			#Architecturally disorganized tissue that appears to be native to the site.
			#No significant growth (vis-à-vis the surrounding tissue).

			VL opinion: ''hamartoma'' (and ''choristoma'') are useless descriptors and the terms should just be done away with.

	==Site specific==		==Site specific==

Michael: +site specific section

2011-08-24T19:36:04Z

+site specific section

← Older revision		Revision as of 19:36, 24 August 2011
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	*If #2 does ''not'' apply it is a ''choristomas''.		*If #2 does ''not'' apply it is a ''choristomas''.
	*"Disorganized" in #1 separates it from hypertrophy and hyperplasia (quasi-physiologic processes).		*"Disorganized" in #1 separates it from hypertrophy and hyperplasia (quasi-physiologic processes).

			==Site specific==
			*[[Pulmonary hamartoma]].
			*[[Splenic hamartoma]].

	==See also==		==See also==
	*[[Basics]].		*[[Basics]].
	*[[Cancer]].		*[[Cancer]].
	*[[Pulmonary hamartoma]].

	==References==		==References==

← Older revision		Revision as of 16:02, 29 May 2012
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	*[[Basics]].		*[[Basics]].
	*[[Cancer]].		*[[Cancer]].
			*[[Odontoma]].

	==References==		==References==