Glycogenic acanthosis of the esophagus - Revision history

Michael: /* Microscopic */

2015-05-16T10:44:00Z

Microscopic

← Older revision		Revision as of 10:44, 16 May 2015
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	**Superficial clearing of the cytoplasm.		**Superficial clearing of the cytoplasm.
	**Thickening.		**Thickening.
			*No significant [[nuclear atypia]].

	===Images===		===Images===

Michael: +stains

2015-05-16T10:38:19Z

+stains

← Older revision		Revision as of 10:38, 16 May 2015
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	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx =
	\| Stains =		\| Stains = PAS +ve, PASD -ve
	\| IHC =		\| IHC =
	\| EM =		\| EM =
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	====www====		====www====
	*[http://scielo.isciii.es/pdf/diges/v102n5/carta3.pdf Glycogenic acanthosis (isciii.es)].		*[http://scielo.isciii.es/pdf/diges/v102n5/carta3.pdf Glycogenic acanthosis (isciii.es)].

			==Stains==
			Features:<ref name=pmid6981928>{{Cite journal \| last1 = Glick \| first1 = SN. \| last2 = Teplick \| first2 = SK. \| last3 = Goldstein \| first3 = J. \| last4 = Stead \| first4 = JA. \| last5 = Zitomer \| first5 = N. \| title = Glycogenic acanthosis of the esophagus. \| journal = AJR Am J Roentgenol \| volume = 139 \| issue = 4 \| pages = 683-8 \| month = Oct \| year = 1982 \| doi = 10.2214/ajr.139.4.683 \| PMID = 6981928 }}</ref>
			*[[PAS stain\|PAS]] +ve.
			*[[PASD stain\|PASD]] -ve.

	==See also==		==See also==

Michael at 10:31, 16 May 2015

2015-05-16T10:31:38Z

← Older revision		Revision as of 10:31, 16 May 2015
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	\| Grossing =		\| Grossing =
	\| Site = [[esophagus]]		\| Site = [[esophagus]]
	\| Assdx = [[gastroesophageal reflux disease]] ~~(???)~~		\| Assdx = possibly associated with [[gastroesophageal reflux disease]]
	\| Syndromes =		\| Syndromes = possibly [[Cowden's disease]] when diffuse
	\| Clinicalhx = ingestion of hot liquids (???)		\| Clinicalhx = ingestion of hot liquids (???)
	\| Signs =		\| Signs =
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	\| Tx =		\| Tx =
	}}		}}
	'''Glycogenic acanthosis of the esophagus''' is an uncommon benign change of the [[esophagus]] with a distinctive endoscopic appearance.		'''Glycogenic acanthosis of the esophagus''', abbreviated '''GAE''', is an uncommon benign change of the [[esophagus]] with a distinctive endoscopic appearance.

	==General==		==General==

Michael at 10:28, 16 May 2015

2015-05-16T10:28:18Z

← Older revision		Revision as of 10:28, 16 May 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Acanthosis_and_superficial_clearing_of_the_esophagus_-_alt_--_intermed_mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Glycogenic acanthosis of the esophagus. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = squamous epithelium with (1) superficial clearing of the cytoplasm, and (2) thickening		\| Micro = squamous epithelium with (1) superficial clearing of the cytoplasm, and (2) thickening

Michael: /* General */

2015-05-16T10:27:16Z

General

← Older revision		Revision as of 10:27, 16 May 2015
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	*May be associated with [[GERD]];<ref name=pmid8409304/><ref name=pmid22798107>{{Cite journal \| last1 = Nazligül \| first1 = Y. \| last2 = Aslan \| first2 = M. \| last3 = Esen \| first3 = R. \| last4 = Yeniova \| first4 = AÖ. \| last5 = Kefeli \| first5 = A. \| last6 = Küçükazman \| first6 = M. \| last7 = Dülger \| first7 = AC. \| last8 = Celik \| first8 = Y. \| title = Benign glycogenic acanthosis lesions of the esophagus. \| journal = Turk J Gastroenterol \| volume = 23 \| issue = 3 \| pages = 199-202 \| month = Jun \| year = 2012 \| doi = \| PMID = 22798107 }}</ref> however, lesions do not resolve with [[Proton pump inhibitor\|PPI]] treatment.<ref name=pmid25632181/>		*May be associated with [[GERD]];<ref name=pmid8409304/><ref name=pmid22798107>{{Cite journal \| last1 = Nazligül \| first1 = Y. \| last2 = Aslan \| first2 = M. \| last3 = Esen \| first3 = R. \| last4 = Yeniova \| first4 = AÖ. \| last5 = Kefeli \| first5 = A. \| last6 = Küçükazman \| first6 = M. \| last7 = Dülger \| first7 = AC. \| last8 = Celik \| first8 = Y. \| title = Benign glycogenic acanthosis lesions of the esophagus. \| journal = Turk J Gastroenterol \| volume = 23 \| issue = 3 \| pages = 199-202 \| month = Jun \| year = 2012 \| doi = \| PMID = 22798107 }}</ref> however, lesions do not resolve with [[Proton pump inhibitor\|PPI]] treatment.<ref name=pmid25632181/>
	*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>		*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>
			*Described in the context of [[Cowden's disease]] when seen diffusely.<ref name=pmid9177527>{{Cite journal \| last1 = Kay \| first1 = PS. \| last2 = Soetikno \| first2 = RM. \| last3 = Mindelzun \| first3 = R. \| last4 = Young \| first4 = HS. \| title = Diffuse esophageal glycogenic acanthosis: an endoscopic marker of Cowden's disease. \| journal = Am J Gastroenterol \| volume = 92 \| issue = 6 \| pages = 1038-40 \| month = Jun \| year = 1997 \| doi = \| PMID = 9177527 }}</ref>

	==Gross/endoscopic==		==Gross/endoscopic==

Michael: /* General */

2015-05-16T10:24:30Z

General

← Older revision		Revision as of 10:24, 16 May 2015
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	*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal \| last1 = Vadva \| first1 = MD. \| last2 = Triadafilopoulos \| first2 = G. \| title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. \| journal = J Clin Gastroenterol \| volume = 17 \| issue = 1 \| pages = 79-83 \| month = Jul \| year = 1993 \| doi = \| PMID = 8409304 }}</ref>		*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal \| last1 = Vadva \| first1 = MD. \| last2 = Triadafilopoulos \| first2 = G. \| title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. \| journal = J Clin Gastroenterol \| volume = 17 \| issue = 1 \| pages = 79-83 \| month = Jul \| year = 1993 \| doi = \| PMID = 8409304 }}</ref>
	*Benign.<ref name=pmid25632181>{{Cite journal \| last1 = Tsai \| first1 = SJ. \| last2 = Lin \| first2 = CC. \| last3 = Chang \| first3 = CW. \| last4 = Hung \| first4 = CY. \| last5 = Shieh \| first5 = TY. \| last6 = Wang \| first6 = HY. \| last7 = Shih \| first7 = SC. \| last8 = Chen \| first8 = MJ. \| title = Benign esophageal lesions: endoscopic and pathologic features. \| journal = World J Gastroenterol \| volume = 21 \| issue = 4 \| pages = 1091-8 \| month = Jan \| year = 2015 \| doi = 10.3748/wjg.v21.i4.1091 \| PMID = 25632181 }}</ref>		*Benign.<ref name=pmid25632181>{{Cite journal \| last1 = Tsai \| first1 = SJ. \| last2 = Lin \| first2 = CC. \| last3 = Chang \| first3 = CW. \| last4 = Hung \| first4 = CY. \| last5 = Shieh \| first5 = TY. \| last6 = Wang \| first6 = HY. \| last7 = Shih \| first7 = SC. \| last8 = Chen \| first8 = MJ. \| title = Benign esophageal lesions: endoscopic and pathologic features. \| journal = World J Gastroenterol \| volume = 21 \| issue = 4 \| pages = 1091-8 \| month = Jan \| year = 2015 \| doi = 10.3748/wjg.v21.i4.1091 \| PMID = 25632181 }}</ref>
	*May be associated with [[GERD]];<ref name=pmid8409304/> however, lesions do not resolve with [[Proton pump inhibitor\|PPI]] treatment.<ref name=pmid25632181/>		*May be associated with [[GERD]];<ref name=pmid8409304/><ref name=pmid22798107>{{Cite journal \| last1 = Nazligül \| first1 = Y. \| last2 = Aslan \| first2 = M. \| last3 = Esen \| first3 = R. \| last4 = Yeniova \| first4 = AÖ. \| last5 = Kefeli \| first5 = A. \| last6 = Küçükazman \| first6 = M. \| last7 = Dülger \| first7 = AC. \| last8 = Celik \| first8 = Y. \| title = Benign glycogenic acanthosis lesions of the esophagus. \| journal = Turk J Gastroenterol \| volume = 23 \| issue = 3 \| pages = 199-202 \| month = Jun \| year = 2012 \| doi = \| PMID = 22798107 }}</ref> however, lesions do not resolve with [[Proton pump inhibitor\|PPI]] treatment.<ref name=pmid25632181/>
	*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>		*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>

Michael: +infobox

2015-05-16T10:22:00Z

+infobox

← Older revision		Revision as of 10:22, 16 May 2015
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = squamous epithelium with (1) superficial clearing of the cytoplasm, and (2) thickening
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[esophagus]]
			\| Assdx = [[gastroesophageal reflux disease]] (???)
			\| Syndromes =
			\| Clinicalhx = ingestion of hot liquids (???)
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy = raised grey/white lesions
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Glycogenic acanthosis of the esophagus''' is an uncommon benign change of the [[esophagus]] with a distinctive endoscopic appearance.		'''Glycogenic acanthosis of the esophagus''' is an uncommon benign change of the [[esophagus]] with a distinctive endoscopic appearance.

Michael: /* General */

2015-05-16T10:17:19Z

General

← Older revision		Revision as of 10:17, 16 May 2015
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	*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal \| last1 = Vadva \| first1 = MD. \| last2 = Triadafilopoulos \| first2 = G. \| title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. \| journal = J Clin Gastroenterol \| volume = 17 \| issue = 1 \| pages = 79-83 \| month = Jul \| year = 1993 \| doi = \| PMID = 8409304 }}</ref>		*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal \| last1 = Vadva \| first1 = MD. \| last2 = Triadafilopoulos \| first2 = G. \| title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. \| journal = J Clin Gastroenterol \| volume = 17 \| issue = 1 \| pages = 79-83 \| month = Jul \| year = 1993 \| doi = \| PMID = 8409304 }}</ref>
	*Benign.<ref name=pmid25632181>{{Cite journal \| last1 = Tsai \| first1 = SJ. \| last2 = Lin \| first2 = CC. \| last3 = Chang \| first3 = CW. \| last4 = Hung \| first4 = CY. \| last5 = Shieh \| first5 = TY. \| last6 = Wang \| first6 = HY. \| last7 = Shih \| first7 = SC. \| last8 = Chen \| first8 = MJ. \| title = Benign esophageal lesions: endoscopic and pathologic features. \| journal = World J Gastroenterol \| volume = 21 \| issue = 4 \| pages = 1091-8 \| month = Jan \| year = 2015 \| doi = 10.3748/wjg.v21.i4.1091 \| PMID = 25632181 }}</ref>		*Benign.<ref name=pmid25632181>{{Cite journal \| last1 = Tsai \| first1 = SJ. \| last2 = Lin \| first2 = CC. \| last3 = Chang \| first3 = CW. \| last4 = Hung \| first4 = CY. \| last5 = Shieh \| first5 = TY. \| last6 = Wang \| first6 = HY. \| last7 = Shih \| first7 = SC. \| last8 = Chen \| first8 = MJ. \| title = Benign esophageal lesions: endoscopic and pathologic features. \| journal = World J Gastroenterol \| volume = 21 \| issue = 4 \| pages = 1091-8 \| month = Jan \| year = 2015 \| doi = 10.3748/wjg.v21.i4.1091 \| PMID = 25632181 }}</ref>
	*May be associated with [[GERD]];<ref name=pmid8409304/> however, lesions do not resolve with [[PPI]] treatment.<ref name=pmid25632181/>		*May be associated with [[GERD]];<ref name=pmid8409304/> however, lesions do not resolve with [[Proton pump inhibitor\|PPI]] treatment.<ref name=pmid25632181/>
	*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>		*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>

Michael: more general, refs

2015-05-16T10:16:33Z

more general, refs

← Older revision		Revision as of 10:16, 16 May 2015
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	'''Glycogenic acanthosis of the esophagus''' is a benign ~~uncommon~~ change of the [[esophagus]].		'''Glycogenic acanthosis of the esophagus''' is an uncommon benign change of the [[esophagus]] with a distinctive endoscopic appearance.

	==General==		==General==
	*Uncommon.		*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal \| last1 = Vadva \| first1 = MD. \| last2 = Triadafilopoulos \| first2 = G. \| title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. \| journal = J Clin Gastroenterol \| volume = 17 \| issue = 1 \| pages = 79-83 \| month = Jul \| year = 1993 \| doi = \| PMID = 8409304 }}</ref>
	*Benign.		*Benign.<ref name=pmid25632181>{{Cite journal \| last1 = Tsai \| first1 = SJ. \| last2 = Lin \| first2 = CC. \| last3 = Chang \| first3 = CW. \| last4 = Hung \| first4 = CY. \| last5 = Shieh \| first5 = TY. \| last6 = Wang \| first6 = HY. \| last7 = Shih \| first7 = SC. \| last8 = Chen \| first8 = MJ. \| title = Benign esophageal lesions: endoscopic and pathologic features. \| journal = World J Gastroenterol \| volume = 21 \| issue = 4 \| pages = 1091-8 \| month = Jan \| year = 2015 \| doi = 10.3748/wjg.v21.i4.1091 \| PMID = 25632181 }}</ref>
			*May be associated with [[GERD]];<ref name=pmid8409304/> however, lesions do not resolve with [[PPI]] treatment.<ref name=pmid25632181/>
	*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>		*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>

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	===Image===		===Image===
	*[http://en.wikipedia.org/wiki/File:Glycogenic_acanthosis.jpg Glycogenic acanthosis (WP)].		*[http://en.wikipedia.org/wiki/File:Glycogenic_acanthosis.jpg Glycogenic acanthosis (WP)].
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306152/figure/F6/ Glycogenic acanthosis (nih.gov)].<ref name=pmid25632181/>

	==Microscopic==		==Microscopic==
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	==See also==		==See also==
	*[[Esophagus]].		*[[Esophagus]].
			*[[Gastroesophageal reflux disease]].

	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:Gastrointestinal pathology]]		[[Category:Gastrointestinal pathology]]

Michael: /* Images */ +add

2015-05-16T10:04:25Z

Images: +add

← Older revision		Revision as of 10:04, 16 May 2015
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	===Images===		===Images===
			<gallery>
			Image: Acanthosis and superficial clearing of the esophagus -- low mag.jpg \| GAE - low mag.
			Image: Acanthosis and superficial clearing of the esophagus -- intermed mag.jpg \| GAE - intermed. mag.
			Image: Acanthosis and superficial clearing of the esophagus - alt -- intermed mag.jpg \| GAE - intermed. mag.
			Image: Acanthosis and superficial clearing of the esophagus -- high mag.jpg \| GAE - high mag.

			Image: Acanthosis and superficial clearing of the esophagus - b -- intermed mag.jpg \| GAE - intermed. mag.
			Image: Acanthosis and superficial clearing of the esophagus - b -- high mag.jpg \| GAE - high mag.
			</gallery>
			====www====
	*[http://scielo.isciii.es/pdf/diges/v102n5/carta3.pdf Glycogenic acanthosis (isciii.es)].		*[http://scielo.isciii.es/pdf/diges/v102n5/carta3.pdf Glycogenic acanthosis (isciii.es)].