Ganglioneuroma - Revision history

Michael at 00:29, 5 May 2016

2016-05-05T00:29:28Z

← Older revision		Revision as of 00:29, 5 May 2016
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	*[http://www.webpathology.com/image.asp?case=84&n=1 Ganglioneuroma (webpathology.com)].		*[http://www.webpathology.com/image.asp?case=84&n=1 Ganglioneuroma (webpathology.com)].

	===Microscopic===		==Microscopic==
	Features:		Features:
	*Ganglion cells - '''key feature'''.		*Ganglion cells - '''key feature'''.

Michael at 21:33, 4 May 2016

2016-05-04T21:33:06Z

← Older revision		Revision as of 21:33, 4 May 2016
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	\| Image = Adrenal Ganglioneuroma MP2 14BR***.jpg		\| Image = Adrenal Ganglioneuroma MP2 14BR***.jpg
	\| Width =		\| Width =
	\| Caption = Adrenal Ganglioneuroma [[H&E stain]].		\| Caption = Adrenal Ganglioneuroma. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro =		\| Micro = ganglion cells (large cells with large nucleus and prominent nucleolus), disordered fibrinous-like material, eosinophilic granular bodies
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx = [[ganglioneuroblastoma]]
	\| Stains =		\| Stains =
	\| IHC = ~~Syn~~+ve, S-100+ve		\| IHC = synaptophysin +ve, S-100 +ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =
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	\| Gross = solid, firm, white		\| Gross = solid, firm, white
	\| Grossing =		\| Grossing =
	\| Site = usually adrenal or retroperitoneal		\| Site = usually adrenal or retroperitoneal, paraspinal
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
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	\| Signs =		\| Signs =
	\| Symptoms =		\| Symptoms =
	\| Prevalence =		\| Prevalence = uncommon
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads =

Michael: /* IHC */

2016-05-04T21:30:30Z

IHC

← Older revision		Revision as of 21:30, 4 May 2016
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	*Spindle cells: S-100 +ve.		*Spindle cells: S-100 +ve.
	*Ganglion cells: NSE, synaptophysin, NF.		*Ganglion cells: NSE, synaptophysin, NF.

			==Sign out==
			<pre>
			Paraspinal Lesion, Right, Core Biopsy:
			- Ganglioneuroma.

			Comment:
			The lesion stains as follows:
			POSITIVE: S-100 & vimentin (stroma, ganglion cells), synaptophysin (ganglion cells only).
			NEGATIVE: AE1/AE3, CD34.
			PROLIFERATION (Ki-67): <1% of cells.
			</pre>

	==See also==		==See also==

Jensflorian: +infobox

2015-06-29T08:55:26Z

+infobox

← Older revision		Revision as of 08:55, 29 June 2015
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Adrenal Ganglioneuroma MP2 14BR***.jpg
			\| Width =
			\| Caption = Adrenal Ganglioneuroma [[H&E stain]].
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC = Syn+ve, S-100+ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = solid, firm, white
			\| Grossing =
			\| Site = usually adrenal or retroperitoneal
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence =
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = good
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Ganglioneuroma''' is a benign neuroblasic tumour. It is also known as '''ganglioma'''.<ref>URL: [http://medical-dictionary.thefreedictionary.com/ganglioma http://medical-dictionary.thefreedictionary.com/ganglioma]. Accessed on: 8 November 2010.</ref>		'''Ganglioneuroma''' is a benign neuroblasic tumour. It is also known as '''ganglioma'''.<ref>URL: [http://medical-dictionary.thefreedictionary.com/ganglioma http://medical-dictionary.thefreedictionary.com/ganglioma]. Accessed on: 8 November 2010.</ref>

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	<gallery>		<gallery>
	Image:Adrenal_ganglioneuroma_02.JPG \| Adrenal ganglioneuroma. (WC)		Image:Adrenal_ganglioneuroma_02.JPG \| Adrenal ganglioneuroma. (WC)
	~~File:Ganglioneuroma.jpg \| Abdominal Ganglioneuroma, HE stain. (WC/jensflorian)~~
	~~File:Retroperitoneum Ganglioneuroma (4165776371).jpg\| Retroperitoneal Ganglioneuroma. (Ed Uthman)~~
	~~File:Adrenal Ganglioneuroma MP2 CTR.jpg \| Bipolar ganglion cell in adrenal Ganglioneuroma (WC/Sarahkayb)~~
	~~File:Adrenal Ganglioneuroma LP 14BR***.jpg \| Adrenal Ganglioneuroma, low magnification (WC/Sarahkayb)~~
	~~File:Adrenal Ganglioneuroma MP2 14BR***.jpg \| Adrenal Ganglioneuroma, high magnification (WC/Sarahkayb)~~
	~~File:Adrenal Ganglioneuroma Syn 14BR***.jpg \| Adrenal Ganglioneuroma, Synaptophysin (WC/Sarahkayb)~~
	~~File:Ganglioneuroma (1).jpg \| Histopathological image of ganglioneuroma in the posterior wall of pharynx. (WC/KGH)~~

	</gallery>		</gallery>
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	Image:Adrenal Ganglioneurona 2 MP2 PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)		Image:Adrenal Ganglioneurona 2 MP2 PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
	Image:Adrenal Ganglioneuroma MP PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)		Image:Adrenal Ganglioneuroma MP PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			File:Ganglioneuroma.jpg \| Abdominal Ganglioneuroma, HE stain. (WC/jensflorian)
			File:Retroperitoneum Ganglioneuroma (4165776371).jpg\| Retroperitoneal Ganglioneuroma. (Ed Uthman)
			File:Ganglioneuroma (1).jpg \| Histopathological image of ganglioneuroma in the posterior wall of pharynx. (WC/KGH)
			File:Ganglioneuroma_-_high_mag.jpg \| Ganglioneuroma in colonic biopsy (WC/Nephron)
			File:Ganglioneuroma_-_very_high_mag.jpg\| Ganglioneuroma in colonic biopsy, high mag (WC/Nephron)
	</gallery>		</gallery>
	www:		www:

Jensflorian: /* Images */ added from wikimedia commons

2015-06-29T08:47:58Z

Images: added from wikimedia commons

← Older revision		Revision as of 08:47, 29 June 2015
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	<gallery>		<gallery>
	Image:Adrenal_ganglioneuroma_02.JPG \| Adrenal ganglioneuroma. (WC)		Image:Adrenal_ganglioneuroma_02.JPG \| Adrenal ganglioneuroma. (WC)
			File:Ganglioneuroma.jpg \| Abdominal Ganglioneuroma, HE stain. (WC/jensflorian)
			File:Retroperitoneum Ganglioneuroma (4165776371).jpg\| Retroperitoneal Ganglioneuroma. (Ed Uthman)
			File:Adrenal Ganglioneuroma MP2 CTR.jpg \| Bipolar ganglion cell in adrenal Ganglioneuroma (WC/Sarahkayb)
			File:Adrenal Ganglioneuroma LP 14BR***.jpg \| Adrenal Ganglioneuroma, low magnification (WC/Sarahkayb)
			File:Adrenal Ganglioneuroma MP2 14BR***.jpg \| Adrenal Ganglioneuroma, high magnification (WC/Sarahkayb)
			File:Adrenal Ganglioneuroma Syn 14BR***.jpg \| Adrenal Ganglioneuroma, Synaptophysin (WC/Sarahkayb)
			File:Ganglioneuroma (1).jpg \| Histopathological image of ganglioneuroma in the posterior wall of pharynx. (WC/KGH)

	</gallery>		</gallery>
	www:		www:

Sarah: /* Images */

2015-03-08T13:05:58Z

Images

← Older revision		Revision as of 13:05, 8 March 2015
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	Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)		Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)
	Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)		Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)
			Image:Adrenal Ganglioneuroma MP CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
	Image:Adrenal Ganglioneuroma MP2 CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)		Image:Adrenal Ganglioneuroma MP2 CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
	~~Image:Adrenal Ganglioneuroma MP CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)~~
	Image:Adrenal Ganglioneuroma LP 14BR***.jpg\|Adrenal Ganglioneuroma - Low power (SKB)		Image:Adrenal Ganglioneuroma LP 14BR***.jpg\|Adrenal Ganglioneuroma - Low power (SKB)
	Image:Adrenal Ganglioneuroma MP 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)		Image:Adrenal Ganglioneuroma MP 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)

Sarah: /* Images */

2015-03-08T13:02:49Z

Images

← Older revision		Revision as of 13:02, 8 March 2015
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	Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)		Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)
	Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)		Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)
			Image:Adrenal Ganglioneuroma MP2 CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma MP CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma LP 14BR***.jpg\|Adrenal Ganglioneuroma - Low power (SKB)
			Image:Adrenal Ganglioneuroma MP 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma MP2 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma HP2 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma HP 14BR***.jpg\|Adrenal Ganglioneuroma - High power (SKB)
			Image:Adrenal Ganglioneuroma Syn 14BR***.jpg\|Adrenal Ganglioneuroma - synaptophysin (SKB)
			Image:Adrenal Ganglioneurona 2 LP PA.JPG\|Adrenal Ganglioneuroma - Low power (SKB)
			Image:Adrenal Ganglioneurona 2 MP PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneurona 2 MP4 PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneurona 2 MP2 PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma MP PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
	</gallery>		</gallery>
	www:		www:

Michael: /* Images */

2014-12-10T07:46:47Z

Images

← Older revision		Revision as of 07:46, 10 December 2014
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	<gallery>		<gallery>
	Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)		Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)
			Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)
	</gallery>		</gallery>
	*[http:~~//it.wikipedia.org/wiki/File:Ganglioneuroma_(1).jpg Ganglioneuroma (WC)].~~		www:
	*[http://www.webpathology.com/image.asp?n=4&Case=84 Ganglioneuroma (webpathology.com)].		*[http://www.webpathology.com/image.asp?n=4&Case=84 Ganglioneuroma (webpathology.com)].
	*[http://www.webpathology.com/image.asp?case=412&n=4 Ganglioneuroma (webpathology.com)].		*[http://www.webpathology.com/image.asp?case=412&n=4 Ganglioneuroma (webpathology.com)].
	*[http://en.wikipedia.org/wiki/File:Ganglion_high_mag.jpg Normal ganglion - high mag. (WC)] .

	==IHC==		==IHC==

Michael: /* Images */

2014-12-10T07:46:06Z

Images

← Older revision		Revision as of 07:46, 10 December 2014
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	===Images===		===Images===
			<gallery>
			Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)
			</gallery>
	*[http://it.wikipedia.org/wiki/File:Ganglioneuroma_(1).jpg Ganglioneuroma (WC)].		*[http://it.wikipedia.org/wiki/File:Ganglioneuroma_(1).jpg Ganglioneuroma (WC)].
	*[http://www.webpathology.com/image.asp?n=4&Case=84 Ganglioneuroma (webpathology.com)].		*[http://www.webpathology.com/image.asp?n=4&Case=84 Ganglioneuroma (webpathology.com)].

Michael: split out

2014-12-10T07:34:09Z

split out

← Older revision		Revision as of 07:34, 10 December 2014
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	#~~redirect~~ [[~~Neuropathology~~ tumours#Ganglioneuroma]]		'''Ganglioneuroma''' is a benign neuroblasic tumour. It is also known as '''ganglioma'''.<ref>URL: [http://medical-dictionary.thefreedictionary.com/ganglioma http://medical-dictionary.thefreedictionary.com/ganglioma]. Accessed on: 8 November 2010.</ref>

			It should '''not''' to be confused with ''[[ganglioglioma]]''.

			==General==
			*May be retroperitoneal.
			*Occasionally found in the GI tract - may form [[Gastrointestinal_tract_polyps#Ganglioneuroma\|colonic polyp]].
			*Multiple ganglioneuromas may be due to [[multiple endocrine neoplasia IIb]].

			Classification:
			*In a grouping known as ''neuroblastic tumours'' which includes:<ref name=pmid10421272>{{cite journal \|author=Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B \|title=Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee \|journal=Cancer \|volume=86 \|issue=2 \|pages=349–63 \|year=1999 \|month=July \|pmid=10421272 \|doi= \|url=}}</ref>
			**Ganglioneuroma (benign).
			**[[Ganglioneuroblastoma]] (intermediate).
			**[[Neuroblastoma]] (aggressive).

			==Gross==
			*Solid.
			*White.
			*Firm.
			*Well-circumscribed.
			*May be nodular.

			===Images===
			<gallery>
			Image:Adrenal_ganglioneuroma_02.JPG \| Adrenal ganglioneuroma. (WC)
			</gallery>
			www:
			*[http://www.webpathology.com/image.asp?case=84&n=1 Ganglioneuroma (webpathology.com)].

			===Microscopic===
			Features:
			*Ganglion cells - '''key feature'''.
			**Large cells with large nucleus.
			***Prominent nucleolus.
			*Disordered fibrinous-like material.
			*Eosinophilic granular bodies.<ref>R. Kiehl. 8 November 2010.</ref>

			See: ''[[adrenal ganglioneuroma]]'', ''[[Gastrointestinal tract polyps#Ganglioneuroma\|colonic ganglioneuroma]]''.

			===Images===
			*[http://it.wikipedia.org/wiki/File:Ganglioneuroma_(1).jpg Ganglioneuroma (WC)].
			*[http://www.webpathology.com/image.asp?n=4&Case=84 Ganglioneuroma (webpathology.com)].
			*[http://www.webpathology.com/image.asp?case=412&n=4 Ganglioneuroma (webpathology.com)].
			*[http://en.wikipedia.org/wiki/File:Ganglion_high_mag.jpg Normal ganglion - high mag. (WC)] .

			==IHC==
			Features:<ref>{{Ref GLP\|217}}</ref>
			*Spindle cells: S-100 +ve.
			*Ganglion cells: NSE, synaptophysin, NF.

			==See also==
			*[[Neuropathology tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Neuropathology tumours]]

← Older revision		Revision as of 13:05, 8 March 2015
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	Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)		Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)
	Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)		Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)
			Image:Adrenal Ganglioneuroma MP CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
	Image:Adrenal Ganglioneuroma MP2 CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)		Image:Adrenal Ganglioneuroma MP2 CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
	~~Image:Adrenal Ganglioneuroma MP CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)~~
	Image:Adrenal Ganglioneuroma LP 14BR***.jpg\|Adrenal Ganglioneuroma - Low power (SKB)		Image:Adrenal Ganglioneuroma LP 14BR***.jpg\|Adrenal Ganglioneuroma - Low power (SKB)
	Image:Adrenal Ganglioneuroma MP 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)		Image:Adrenal Ganglioneuroma MP 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)

← Older revision		Revision as of 13:02, 8 March 2015
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	Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)		Image:Ganglioneuroma_(1).jpg \| Ganglioneuroma. (WC)
	Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)		Image:Ganglion_high_mag.jpg \| A normal ganglion. (WC)
			Image:Adrenal Ganglioneuroma MP2 CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma MP CTR.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma LP 14BR***.jpg\|Adrenal Ganglioneuroma - Low power (SKB)
			Image:Adrenal Ganglioneuroma MP 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma MP2 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma HP2 14BR***.jpg\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma HP 14BR***.jpg\|Adrenal Ganglioneuroma - High power (SKB)
			Image:Adrenal Ganglioneuroma Syn 14BR***.jpg\|Adrenal Ganglioneuroma - synaptophysin (SKB)
			Image:Adrenal Ganglioneurona 2 LP PA.JPG\|Adrenal Ganglioneuroma - Low power (SKB)
			Image:Adrenal Ganglioneurona 2 MP PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneurona 2 MP4 PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneurona 2 MP2 PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
			Image:Adrenal Ganglioneuroma MP PA.JPG\|Adrenal Ganglioneuroma - Medium power (SKB)
	</gallery>		</gallery>
	www:		www: