Fundic gland polyp - Revision history

Michael: /* Multiple polyps with PPI use */ tweak

2022-05-16T18:55:17Z

Multiple polyps with PPI use: tweak

← Older revision		Revision as of 18:55, 16 May 2022
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	PPI use appears to be the most likely explanation in this case,		PPI use appears to be the most likely explanation in this case,
	in the context of the provided history; however, FAP should be		in the context of the provided history; however, FAP and GAPPS should be
	considered clinically.		considered clinically.
	</pre>		</pre>

Michael: /* Polyposis */ tweak

2022-04-19T14:39:19Z

Polyposis: tweak

← Older revision		Revision as of 14:39, 19 April 2022
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	- Fundic gland polyposis, see comment.		- Fundic gland polyposis, see comment.
	- NEGATIVE for intestinal metaplasia.		- NEGATIVE for intestinal metaplasia.
	- NEGATIVE for ~~helicobacter~~-like organisms.		- NEGATIVE for Helicobacter-like organisms.
	- NEGATIVE for dysplasia and negative for malignancy.		- NEGATIVE for dysplasia and negative for malignancy.

Michael: /* Polyposis */ tweak

2022-01-26T17:09:56Z

Polyposis: tweak

← Older revision		Revision as of 17:09, 26 January 2022
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	were seen at the time of grossing.		were seen at the time of grossing.

	Fundic gland polyps are reported in association with proton pump inhibitor use ~~and in~~		Fundic gland polyps are reported in association with proton pump inhibitor use, familial
	~~association with familial~~ adenomatous polyposis (FAP). The possibility of FAP and GAPPS		adenomatous polyposis (FAP), and gastric adenocarcinoma and proximal polyposis of the
	should be considered.		stomach (GAPPS). The possibility of FAP and GAPPS should be considered.
	</pre>		</pre>

Michael at 17:08, 26 January 2022

2022-01-26T17:08:58Z

← Older revision		Revision as of 17:08, 26 January 2022
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	COMMENT:		COMMENT:
	Several fundic gland polyps were removed previously. Fundic gland		Several fundic gland polyps were removed previously. Fundic gland
	polyps are associated with familial adenomatous polyposis (FAP)		polyps are associated with familial adenomatous polyposis (FAP),
			gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS),
	and proton pump inhibitor (PPI) use.		and proton pump inhibitor (PPI) use.

Line 112:		Line 113:
	were seen at the time of grossing.		were seen at the time of grossing.

	Fundic gland polyps are reported in association with proton pump inhibitor use ~~and in~~		Fundic gland polyps are reported in association with proton pump inhibitor use, familial
	~~association with familial~~ adenomatous polyposis (FAP). The possibility of FAP should be		adenomatous polyposis (FAP), and gastric adenocarcinoma and proximal polyposis of the
	~~investigated~~.		stomach (GAPPS). The possibility of FAP and GAPPS should be considered.
	</pre>		</pre>

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	Fundic gland polyps are reported in association with proton pump inhibitor use and in		Fundic gland polyps are reported in association with proton pump inhibitor use and in
	association with familial adenomatous polyposis (FAP). The possibility of FAP should be		association with familial adenomatous polyposis (FAP). The possibility of FAP and GAPPS
	~~investigated~~.		should be considered.
	</pre>		</pre>

Michael at 16:51, 16 September 2019

2019-09-16T16:51:27Z

← Older revision		Revision as of 16:51, 16 September 2019
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	\| Site = [[stomach]] - usually fundus		\| Site = [[stomach]] - usually fundus
	\| Assdx = [[gastroesophageal reflux disease]] - thus PPI use		\| Assdx = [[gastroesophageal reflux disease]] - thus PPI use
	\| Syndromes = [[familial adenomatous polyposis]]		\| Syndromes = [[familial adenomatous polyposis]], [[gastric adenocarcinoma and proximal polyposis of the stomach]]
	\| Clinicalhx =		\| Clinicalhx =
	\| Signs =		\| Signs =

Michael: /* Clinical significance */ wikify

2019-09-16T16:37:32Z

Clinical significance: wikify

← Older revision		Revision as of 16:37, 16 September 2019
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	*Associated with chronic proton pump inhibitors (PPI) use -- approximately 4x risk.<ref>{{cite journal \|author=Jalving M, Koornstra JJ, Wesseling J, Boezen HM, DE Jong S, Kleibeuker JH \|title=Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy \|journal=Aliment. Pharmacol. Ther. \|volume=24 \|issue=9 \|pages=1341-8 \|year=2006 \|month=November \|pmid=17059515 \|doi=10.1111/j.1365-2036.2006.03127.x \|url=}}</ref>		*Associated with chronic proton pump inhibitors (PPI) use -- approximately 4x risk.<ref>{{cite journal \|author=Jalving M, Koornstra JJ, Wesseling J, Boezen HM, DE Jong S, Kleibeuker JH \|title=Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy \|journal=Aliment. Pharmacol. Ther. \|volume=24 \|issue=9 \|pages=1341-8 \|year=2006 \|month=November \|pmid=17059515 \|doi=10.1111/j.1365-2036.2006.03127.x \|url=}}</ref>
	**PPIs may cause ''fundic gland polyposis'' - extremely rare (two reported cases as of 2012).<ref name=pmid22348851>{{Cite journal \| last1 = Hegedus \| first1 = I. \| last2 = Csizmadia \| first2 = C. \| last3 = Lomb \| first3 = Z. \| last4 = Cseke \| first4 = L. \| last5 = Enkh-Amar \| first5 = Y. \| last6 = Pajor \| first6 = L. \| last7 = Bogner \| first7 = B. \| title = [Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy]. \| journal = Orv Hetil \| volume = 153 \| issue = 9 \| pages = 351-6 \| month = Mar \| year = 2012 \| doi = 10.1556/OH.2012.29313 \| PMID = 22348851 }}</ref>		**PPIs may cause ''fundic gland polyposis'' - extremely rare (two reported cases as of 2012).<ref name=pmid22348851>{{Cite journal \| last1 = Hegedus \| first1 = I. \| last2 = Csizmadia \| first2 = C. \| last3 = Lomb \| first3 = Z. \| last4 = Cseke \| first4 = L. \| last5 = Enkh-Amar \| first5 = Y. \| last6 = Pajor \| first6 = L. \| last7 = Bogner \| first7 = B. \| title = [Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy]. \| journal = Orv Hetil \| volume = 153 \| issue = 9 \| pages = 351-6 \| month = Mar \| year = 2012 \| doi = 10.1556/OH.2012.29313 \| PMID = 22348851 }}</ref>
	*Gastric adenocarcinoma and proximal polyposis of the stomach.<ref name=pmid21813476>{{Cite journal \| last1 = Worthley \| first1 = DL. \| last2 = Phillips \| first2 = KD. \| last3 = Wayte \| first3 = N. \| last4 = Schrader \| first4 = KA. \| last5 = Healey \| first5 = S. \| last6 = Kaurah \| first6 = P. \| last7 = Shulkes \| first7 = A. \| last8 = Grimpen \| first8 = F. \| last9 = Clouston \| first9 = A. \| title = Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome. \| journal = Gut \| volume = 61 \| issue = 5 \| pages = 774-9 \| month = May \| year = 2012 \| doi = 10.1136/gutjnl-2011-300348 \| PMID = 21813476 }}</ref>		*[[Gastric adenocarcinoma and proximal polyposis of the stomach]].<ref name=pmid21813476>{{Cite journal \| last1 = Worthley \| first1 = DL. \| last2 = Phillips \| first2 = KD. \| last3 = Wayte \| first3 = N. \| last4 = Schrader \| first4 = KA. \| last5 = Healey \| first5 = S. \| last6 = Kaurah \| first6 = P. \| last7 = Shulkes \| first7 = A. \| last8 = Grimpen \| first8 = F. \| last9 = Clouston \| first9 = A. \| title = Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome. \| journal = Gut \| volume = 61 \| issue = 5 \| pages = 774-9 \| month = May \| year = 2012 \| doi = 10.1136/gutjnl-2011-300348 \| PMID = 21813476 }}</ref>

	Notes:		Notes:

Michael: /* General */ tweak

2019-09-16T15:17:43Z

General: tweak

← Older revision		Revision as of 15:17, 16 September 2019
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	*Associated with chronic proton pump inhibitors (PPI) use -- approximately 4x risk.<ref>{{cite journal \|author=Jalving M, Koornstra JJ, Wesseling J, Boezen HM, DE Jong S, Kleibeuker JH \|title=Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy \|journal=Aliment. Pharmacol. Ther. \|volume=24 \|issue=9 \|pages=1341-8 \|year=2006 \|month=November \|pmid=17059515 \|doi=10.1111/j.1365-2036.2006.03127.x \|url=}}</ref>		*Associated with chronic proton pump inhibitors (PPI) use -- approximately 4x risk.<ref>{{cite journal \|author=Jalving M, Koornstra JJ, Wesseling J, Boezen HM, DE Jong S, Kleibeuker JH \|title=Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy \|journal=Aliment. Pharmacol. Ther. \|volume=24 \|issue=9 \|pages=1341-8 \|year=2006 \|month=November \|pmid=17059515 \|doi=10.1111/j.1365-2036.2006.03127.x \|url=}}</ref>
	**PPIs may cause ''fundic gland polyposis'' - extremely rare (two reported cases as of 2012).<ref name=pmid22348851>{{Cite journal \| last1 = Hegedus \| first1 = I. \| last2 = Csizmadia \| first2 = C. \| last3 = Lomb \| first3 = Z. \| last4 = Cseke \| first4 = L. \| last5 = Enkh-Amar \| first5 = Y. \| last6 = Pajor \| first6 = L. \| last7 = Bogner \| first7 = B. \| title = [Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy]. \| journal = Orv Hetil \| volume = 153 \| issue = 9 \| pages = 351-6 \| month = Mar \| year = 2012 \| doi = 10.1556/OH.2012.29313 \| PMID = 22348851 }}</ref>		**PPIs may cause ''fundic gland polyposis'' - extremely rare (two reported cases as of 2012).<ref name=pmid22348851>{{Cite journal \| last1 = Hegedus \| first1 = I. \| last2 = Csizmadia \| first2 = C. \| last3 = Lomb \| first3 = Z. \| last4 = Cseke \| first4 = L. \| last5 = Enkh-Amar \| first5 = Y. \| last6 = Pajor \| first6 = L. \| last7 = Bogner \| first7 = B. \| title = [Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy]. \| journal = Orv Hetil \| volume = 153 \| issue = 9 \| pages = 351-6 \| month = Mar \| year = 2012 \| doi = 10.1556/OH.2012.29313 \| PMID = 22348851 }}</ref>
			*Gastric adenocarcinoma and proximal polyposis of the stomach.<ref name=pmid21813476>{{Cite journal \| last1 = Worthley \| first1 = DL. \| last2 = Phillips \| first2 = KD. \| last3 = Wayte \| first3 = N. \| last4 = Schrader \| first4 = KA. \| last5 = Healey \| first5 = S. \| last6 = Kaurah \| first6 = P. \| last7 = Shulkes \| first7 = A. \| last8 = Grimpen \| first8 = F. \| last9 = Clouston \| first9 = A. \| title = Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome. \| journal = Gut \| volume = 61 \| issue = 5 \| pages = 774-9 \| month = May \| year = 2012 \| doi = 10.1136/gutjnl-2011-300348 \| PMID = 21813476 }}</ref>

	Notes:		Notes:

Michael: /* Image */

2016-03-10T22:40:45Z

Image

← Older revision		Revision as of 22:40, 10 March 2016
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	*Polyp - usuallly in fundus, may be in body of stomach.		*Polyp - usuallly in fundus, may be in body of stomach.

	===~~Image~~===		===Images===
	<gallery>		<gallery>
	Image:Endoscopic_view_of_fundic_gland_polyps.jpg \| FGPs on endoscopy. (WC)		Image:Endoscopic_view_of_fundic_gland_polyps.jpg \| FGPs on endoscopy. (WC)

Michael: /* Gross */

2016-03-10T22:40:33Z

Gross

← Older revision		Revision as of 22:40, 10 March 2016
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	*Polyp - usuallly in fundus, may be in body of stomach.		*Polyp - usuallly in fundus, may be in body of stomach.

	Image:		===Image===
	<gallery>		<gallery>
	Image:Endoscopic_view_of_fundic_gland_polyps.jpg \| FGPs on endoscopy. (WC)		Image:Endoscopic_view_of_fundic_gland_polyps.jpg \| FGPs on endoscopy. (WC)

Michael: /* Polyposis */

2016-03-04T16:03:53Z

Polyposis

← Older revision		Revision as of 16:03, 4 March 2016
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	===Polyposis===		===Polyposis===
			<pre>
			Partial Stomach, Sleeve Gastrectomy:
			- Fundic gland polyposis, see comment.
			- NEGATIVE for intestinal metaplasia.
			- NEGATIVE for helicobacter-like organisms.
			- NEGATIVE for dysplasia and negative for malignancy.

			Comment:
			Sixteen fundic gland polyps are identified on microscopy. At least forty polypoid lesions
			were seen at the time of grossing.

			Fundic gland polyps are reported in association with proton pump inhibitor use and in
			association with familial adenomatous polyposis (FAP). The possibility of FAP should be
			investigated.
			</pre>

			====Block letters====
	<pre>		<pre>
	STOMACH, GREATER CURVE, SLEEVE GASTRECTOMY:		STOMACH, GREATER CURVE, SLEEVE GASTRECTOMY: