Fibroadenoma - Revision history

Michael: /* Sign out */ tweak

2021-01-05T19:25:17Z

Sign out: tweak

← Older revision		Revision as of 19:25, 5 January 2021
Line 158:		Line 158:

	==Sign out==		==Sign out==
			<pre>
			Right Partial Breast, Lumpectomy:
			- Fibroadenoma.
			</pre>

			====Micro====
			The sections show a lesion with a pale mildly cellular stroma, and bland glandular elements. No apparent proliferative activity is present. The border is well-circumscribed where seen. Focally, the lesion approaches the inked margin; partial lesion transection cannot be excluded.

			No cytologic atypia is present. No leaf-like architecture is present. No stromal overgrowth is seen. No calcifications are evident. No large cysts are seen.


			===Complex===
	<pre>		<pre>
	Right Breast, Lumpectomy:		Right Breast, Lumpectomy:
Line 164:		Line 176:
	</pre>		</pre>

	===Micro===		====Micro====
	The sections show a lesion with a pale mildly cellular stroma, and bland glandular elements. Minimal mitotic activity is present (2 mitosis/10 HPF, where 1 HPF ~ 0.2376 mm*mm). The border is well-circumscribed where seen. The lesion was shelled-out.		The sections show a lesion with a pale mildly cellular stroma, and bland glandular elements. Minimal mitotic activity is present (2 mitosis/10 HPF, where 1 HPF ~ 0.2376 mm*mm). The border is well-circumscribed where seen. The lesion was shelled-out.

Michael: /* Cellular fibroadenoma */

2017-09-15T14:54:21Z

Cellular fibroadenoma

← Older revision		Revision as of 14:54, 15 September 2017
Line 120:		Line 120:

	Note:		Note:
	*"Cellular" is something that can be subjective. One definition of "cellular" is: "stromal cells are touching one another". Jacobs ''et al.'' has a stromal cellularity picture gallery showing ''mild'' (rare ~~stroml cell~~ touching), ''moderate'' and ''marked'' (~~much~~ stromal ~~cell~~ touching).<ref name=pmid16191502>{{Cite journal \| last1 = Jacobs \| first1 = TW. \| last2 = Chen \| first2 = YY. \| last3 = Guinee \| first3 = DG. \| last4 = Holden \| first4 = JA. \| last5 = Cha \| first5 = I. \| last6 = Bauermeister \| first6 = DE. \| last7 = Hashimoto \| first7 = B. \| last8 = Wolverton \| first8 = D. \| last9 = Hartzog \| first9 = G. \| title = Fibroepithelial lesions with cellular stroma on breast core needle biopsy: are there predictors of outcome on surgical excision? \| journal = Am J Clin Pathol \| volume = 124 \| issue = 3 \| pages = 342-54 \| month = Sep \| year = 2005 \| doi = 10.1309/5N2C-4N5X-CB8X-W8JL \| PMID = 16191502 }}</ref>		*"Cellular" is something that can be subjective. One definition of "cellular" is: "stromal cells are touching one another". Jacobs ''et al.'' has a stromal cellularity picture gallery showing ''mild'' (rare stromal cells touching), ''moderate'' and ''marked'' (many stromal cells touching).<ref name=pmid16191502>{{Cite journal \| last1 = Jacobs \| first1 = TW. \| last2 = Chen \| first2 = YY. \| last3 = Guinee \| first3 = DG. \| last4 = Holden \| first4 = JA. \| last5 = Cha \| first5 = I. \| last6 = Bauermeister \| first6 = DE. \| last7 = Hashimoto \| first7 = B. \| last8 = Wolverton \| first8 = D. \| last9 = Hartzog \| first9 = G. \| title = Fibroepithelial lesions with cellular stroma on breast core needle biopsy: are there predictors of outcome on surgical excision? \| journal = Am J Clin Pathol \| volume = 124 \| issue = 3 \| pages = 342-54 \| month = Sep \| year = 2005 \| doi = 10.1309/5N2C-4N5X-CB8X-W8JL \| PMID = 16191502 }}</ref>

	====Complex fibroadenoma====		====Complex fibroadenoma====

Michael: /* Cellular fibroadenoma */

2017-09-15T14:53:18Z

Cellular fibroadenoma

← Older revision		Revision as of 14:53, 15 September 2017
Line 118:		Line 118:
	*Cellular.		*Cellular.
	*Mitoses.		*Mitoses.

			Note:
			*"Cellular" is something that can be subjective. One definition of "cellular" is: "stromal cells are touching one another". Jacobs ''et al.'' has a stromal cellularity picture gallery showing ''mild'' (rare stroml cell touching), ''moderate'' and ''marked'' (much stromal cell touching).<ref name=pmid16191502>{{Cite journal \| last1 = Jacobs \| first1 = TW. \| last2 = Chen \| first2 = YY. \| last3 = Guinee \| first3 = DG. \| last4 = Holden \| first4 = JA. \| last5 = Cha \| first5 = I. \| last6 = Bauermeister \| first6 = DE. \| last7 = Hashimoto \| first7 = B. \| last8 = Wolverton \| first8 = D. \| last9 = Hartzog \| first9 = G. \| title = Fibroepithelial lesions with cellular stroma on breast core needle biopsy: are there predictors of outcome on surgical excision? \| journal = Am J Clin Pathol \| volume = 124 \| issue = 3 \| pages = 342-54 \| month = Sep \| year = 2005 \| doi = 10.1309/5N2C-4N5X-CB8X-W8JL \| PMID = 16191502 }}</ref>

	====Complex fibroadenoma====		====Complex fibroadenoma====

Michael at 13:39, 15 September 2017

2017-09-15T13:39:15Z

← Older revision		Revision as of 13:39, 15 September 2017
Line 23:		Line 23:
	\| Prevalence = very common		\| Prevalence = very common
	\| Bloodwork =		\| Bloodwork =
	\| Rads = see ''[[BIRADS]]''		\| Rads = typically BIRADS4 - see ''[[BIRADS]]''
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = benign		\| Prognosis = benign

Michael at 13:39, 15 September 2017

2017-09-15T13:39:01Z

← Older revision		Revision as of 13:39, 15 September 2017
Line 23:		Line 23:
	\| Prevalence = very common		\| Prevalence = very common
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads = see ''[[BIRADS]]''
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = benign		\| Prognosis = benign

Michael: /* Sign out */

2017-09-15T13:12:15Z

Sign out

← Older revision		Revision as of 13:12, 15 September 2017
Line 160:		Line 160:
	- Negative for carcinoma in situ and negative for malignancy.		- Negative for carcinoma in situ and negative for malignancy.
	</pre>		</pre>

			===Micro===
			The sections show a lesion with a pale mildly cellular stroma, and bland glandular elements. Minimal mitotic activity is present (2 mitosis/10 HPF, where 1 HPF ~ 0.2376 mm*mm). The border is well-circumscribed where seen. The lesion was shelled-out.

			No cytologic atypia is present. No leaf-like architecture is present. No stromal overgrowth is seen. No calcifications are evident. No large cysts are seen.

	==See also==		==See also==

Michael at 14:28, 20 June 2016

2016-06-20T14:28:28Z

← Older revision		Revision as of 14:28, 20 June 2016
Line 31:		Line 31:
	}}		}}
	'''Fibroadenoma''', abbreviated '''FA''', is a common benign tumour of the [[breast]].		'''Fibroadenoma''', abbreviated '''FA''', is a common benign tumour of the [[breast]].

			It is a type of [[fibroepithelial tumours of the breast\|fibroepithelial tumour]].

	==General==		==General==

Michael at 20:17, 3 June 2016

2016-06-03T20:17:02Z

← Older revision		Revision as of 20:17, 3 June 2016
Line 30:		Line 30:
	\| Tx = conservative excision		\| Tx = conservative excision
	}}		}}
	'''Fibroadenoma''' is a common benign tumour of the [[breast]].		'''Fibroadenoma''', abbreviated '''FA''', is a common benign tumour of the [[breast]].

	==General==		==General==

Sarah: /* Tubular adenoma of the breast */

2015-03-26T10:01:18Z

Tubular adenoma of the breast

← Older revision		Revision as of 10:01, 26 March 2015
Line 137:		Line 137:
	*Well circumscribed lesion.		*Well circumscribed lesion.
	*Closely packed uniform tubules, lined by a single layer of epithelial cells and an attenuated myoepithelial cell layer.		*Closely packed uniform tubules, lined by a single layer of epithelial cells and an attenuated myoepithelial cell layer.
	*Stroma is sparse~~, distinguishing tubular adenoma from~~ fibroadenoma		*Stroma is generally more sparse than in conventional fibroadenoma

	Images:		Images:

Sarah: /* Tubular adenoma of the breast */

2015-03-26T09:59:49Z

Tubular adenoma of the breast

← Older revision		Revision as of 09:59, 26 March 2015
Line 133:		Line 133:
	*Considered by many a variant of ''fibroadenoma''.		*Considered by many a variant of ''fibroadenoma''.
	**[[IHC]] features of ''[[tubular adenoma]] of the breast'' and ''fibroadenoma'' are similar.<ref>{{Cite journal \| last1 = Maiorano \| first1 = E. \| last2 = Albrizio \| first2 = M. \| title = Tubular adenoma of the breast: an immunohistochemical study of ten cases. \| journal = Pathol Res Pract \| volume = 191 \| issue = 12 \| pages = 1222-30 \| month = Dec \| year = 1995 \| doi = \| PMID = 8927570 }}</ref>		**[[IHC]] features of ''[[tubular adenoma]] of the breast'' and ''fibroadenoma'' are similar.<ref>{{Cite journal \| last1 = Maiorano \| first1 = E. \| last2 = Albrizio \| first2 = M. \| title = Tubular adenoma of the breast: an immunohistochemical study of ten cases. \| journal = Pathol Res Pract \| volume = 191 \| issue = 12 \| pages = 1222-30 \| month = Dec \| year = 1995 \| doi = \| PMID = 8927570 }}</ref>
			*Most present in adults between menarche and menopause.
	Features:<ref name=Ref_BP116>{{Ref BP\|116}}</ref>		Features:<ref name=Ref_BP116>{{Ref BP\|116}}</ref>
	*~~Fibromyxoid stroma (like in~~ a ~~fibroadenoma)~~.		*Well circumscribed lesion.
	*~~Small round glands.~~		*Closely packed uniform tubules, lined by a single layer of epithelial cells and an attenuated myoepithelial cell layer.
			*Stroma is sparse, distinguishing tubular adenoma from fibroadenoma

	Images:		Images: