DNA repair genes - Revision history

Michael at 15:53, 27 May 2014

2014-05-27T15:53:37Z

← Older revision		Revision as of 15:53, 27 May 2014
Line 10:		Line 10:
	!Tumours		!Tumours
	\|-		\|-
	\| BRCA1		\| [[BRCA1]]
	\| familial breast and ovarian cancer		\| familial breast and ovarian cancer
	\| breast, ovary, prostate, pancreas, male breast, fallopian tube		\| breast, ovary, prostate, pancreas, male breast, fallopian tube
	\|-		\|-
	\| BRCA2		\| [[BRCA2]]
	\| familial breast and ovarian cancer 2		\| familial breast and ovarian cancer 2
	\| breast, ovary, prostate, pancreas, stomach, male breast, melanoma, stomach, biliary, pharynx		\| breast, ovary, prostate, pancreas, stomach, male breast, melanoma, stomach, biliary, pharynx

Michael: tweak

2012-05-04T12:59:25Z

tweak

← Older revision		Revision as of 12:59, 4 May 2012
Line 12:		Line 12:
	\| BRCA1		\| BRCA1
	\| familial breast and ovarian cancer		\| familial breast and ovarian cancer
	\| breast, ovary, prostate, pancreas, ~~others~~		\| breast, ovary, prostate, pancreas, male breast, fallopian tube
	\|-		\|-
	\| BRCA2		\| BRCA2
	\| familial breast and ovarian cancer 2		\| familial breast and ovarian cancer 2
	\| breast, ovary, prostate, pancreas, stomach, ~~others~~		\| breast, ovary, prostate, pancreas, stomach, male breast, melanoma, stomach, biliary, pharynx
	\|-		\|-
	\| MSH2		\| MSH2

Michael at 12:56, 4 May 2012

2012-05-04T12:56:58Z

← Older revision		Revision as of 12:56, 4 May 2012
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	\| MSH2		\| MSH2
	\| [[Lynch syndrome]]		\| [[Lynch syndrome]]
	\| [[colorectal carcinoma]], [[endometrial carcinoma]], gastric, pancreas, urothelial, biliary		\| [[colorectal carcinoma\|colorectal]], [[endometrial carcinoma\|endometrial]], [[stomach cancer\|gastric]], pancreas, urothelial, biliary
	\|}		\|}

Michael: tweak

2012-05-04T12:56:21Z

tweak

← Older revision		Revision as of 12:56, 4 May 2012
Line 20:		Line 20:
	\| MSH2		\| MSH2
	\| [[Lynch syndrome]]		\| [[Lynch syndrome]]
	\| [[colorectal carcinoma]], [[endometrial carcinoma]], ~~others~~		\| [[colorectal carcinoma]], [[endometrial carcinoma]], gastric, pancreas, urothelial, biliary
	\|}		\|}

Michael: create

2012-05-04T12:53:35Z

create

New page

'''DNA repair genes''' fix broken DNA. Failure of DNA repair can lead to [[cancer]].

There is a long and growing list of DNA repair genes.<ref>{{Cite journal | last1 = Wood | first1 = RD. | last2 = Mitchell | first2 = M. | last3 = Sgouros | first3 = J. | last4 = Lindahl | first4 = T. | title = Human DNA repair genes. | journal = Science | volume = 291 | issue = 5507 | pages = 1284-9 | month = Feb | year = 2001 | doi = 10.1126/science.1056154 | PMID = 11181991 | URL = http://www.sciencemag.org/content/291/5507/1284.full}}</ref>

==Examples==

{| class="wikitable sortable"
!Gene
!Syndrome
!Tumours
|-
| BRCA1
| familial breast and ovarian cancer
| breast, ovary, prostate, pancreas, others
|-
| BRCA2
| familial breast and ovarian cancer 2
| breast, ovary, prostate, pancreas, stomach, others
|-
| MSH2
| [[Lynch syndrome]]
| [[colorectal carcinoma]], [[endometrial carcinoma]], others
|}

==References==
{{Reflist|1}}

[[Category:Molecular pathology]]