Cytokeratin 5/6 - Revision history

Michael: /* Positive */

2016-05-06T02:18:16Z

Positive

← Older revision		Revision as of 02:18, 6 May 2016
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	==Positive==		==Positive==
	*[[Squamous cell carcinoma]].		*[[Squamous cell carcinoma]].
			**[[Squamous cell carcinoma of the lung]].<ref name=pmid26273374>{{Cite journal \| last1 = Ma \| first1 = Y. \| last2 = Fan \| first2 = M. \| last3 = Dai \| first3 = L. \| last4 = Kang \| first4 = X. \| last5 = Liu \| first5 = Y. \| last6 = Sun \| first6 = Y. \| last7 = Xiong \| first7 = H. \| last8 = Liang \| first8 = Z. \| last9 = Yan \| first9 = W. \| title = Expression of p63 and CK5/6 in early-stage lung squamous cell carcinoma is not only an early diagnostic indicator but also correlates with a good prognosis. \| journal = Thorac Cancer \| volume = 6 \| issue = 3 \| pages = 288-95 \| month = May \| year = 2015 \| doi = 10.1111/1759-7714.12181 \| PMID = 26273374 }}</ref>
	*Benign prostate (basal cells).<ref name=pmid19605815>{{Cite journal \| last1 = Trpkov \| first1 = K. \| last2 = Bartczak-McKay \| first2 = J. \| last3 = Yilmaz \| first3 = A. \| title = Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens. \| journal = Am J Clin Pathol \| volume = 132 \| issue = 2 \| pages = 211-20; quiz 307 \| month = Aug \| year = 2009 \| doi = 10.1309/AJCPGFJP83IXZEUR \| PMID = 19605815 }}</ref>		*Benign prostate (basal cells).<ref name=pmid19605815>{{Cite journal \| last1 = Trpkov \| first1 = K. \| last2 = Bartczak-McKay \| first2 = J. \| last3 = Yilmaz \| first3 = A. \| title = Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens. \| journal = Am J Clin Pathol \| volume = 132 \| issue = 2 \| pages = 211-20; quiz 307 \| month = Aug \| year = 2009 \| doi = 10.1309/AJCPGFJP83IXZEUR \| PMID = 19605815 }}</ref>
	*[[Urothelial carcinoma]].		*[[Urothelial carcinoma]].

Michael: /* Positive */

2016-05-05T21:02:06Z

Positive

← Older revision		Revision as of 21:02, 5 May 2016
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	*[[Urothelial carcinoma]].		*[[Urothelial carcinoma]].
	*[[Malignant mesothelioma]].<ref name=pmid18318582>{{cite journal \|author=Marchevsky AM \|title=Application of immunohistochemistry to the diagnosis of malignant mesothelioma \|journal=Arch. Pathol. Lab. Med. \|volume=132 \|issue=3 \|pages=397-401 \|year=2008 \|month=March \|pmid=18318582 \|doi= \|url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=397}}</ref>		*[[Malignant mesothelioma]].<ref name=pmid18318582>{{cite journal \|author=Marchevsky AM \|title=Application of immunohistochemistry to the diagnosis of malignant mesothelioma \|journal=Arch. Pathol. Lab. Med. \|volume=132 \|issue=3 \|pages=397-401 \|year=2008 \|month=March \|pmid=18318582 \|doi= \|url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=397}}</ref>
			*Reactive mesothelial cells.<ref name=pmid25337222>{{Cite journal \| last1 = Yan \| first1 = J. \| last2 = Wei \| first2 = Q. \| last3 = Jian \| first3 = W. \| last4 = Liu \| first4 = J. \| last5 = Tang \| first5 = H. \| last6 = Ge \| first6 = J. \| last7 = Zhou \| first7 = J. \| last8 = Zhao \| first8 = T. \| title = A fine decision tree consisted of CK5/6, IMP3 and TTF1 for cytological diagnosis among reactive mesothelial cells, metastatic adenocarcinoma of lung and non-lung origin in pleural effusion. \| journal = Int J Clin Exp Pathol \| volume = 7 \| issue = 9 \| pages = 5810-8 \| month = \| year = 2014 \| doi = \| PMID = 25337222 }}</ref>

	==Negative==		==Negative==

Michael at 20:51, 5 May 2016

2016-05-05T20:51:19Z

← Older revision		Revision as of 20:51, 5 May 2016
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	==See also==		==See also==
	*[[Immunohistochemistry]].		*[[Immunohistochemistry]].

			==References==
			{{Reflist\|1}}

	[[Category:Immunohistochemistry]]		[[Category:Immunohistochemistry]]

Michael: /* Use */

2016-05-05T20:50:55Z

Use

← Older revision		Revision as of 20:50, 5 May 2016
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	==Use==		==Use==
	*~~Stain basal cells in prostate - useful for~~ [[~~prostatic~~ adenocarcinoma]] versus [[high-grade prostatic intraepithelial neoplasia]].		*[[Prostatic adenocarcinoma]] versus [[high-grade prostatic intraepithelial neoplasia]] (HGPIN).
			**CK5/6 marks the basal cells: present in HGPIN, absent in cancer.
			*[[Urothelial cell carcinoma]] versus [[prostatic adenocarcinoma]].
			**Positive in UCC, negative in prostate adenocarcinoma.

			==Positive==
			*[[Squamous cell carcinoma]].
			*Benign prostate (basal cells).<ref name=pmid19605815>{{Cite journal \| last1 = Trpkov \| first1 = K. \| last2 = Bartczak-McKay \| first2 = J. \| last3 = Yilmaz \| first3 = A. \| title = Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens. \| journal = Am J Clin Pathol \| volume = 132 \| issue = 2 \| pages = 211-20; quiz 307 \| month = Aug \| year = 2009 \| doi = 10.1309/AJCPGFJP83IXZEUR \| PMID = 19605815 }}</ref>
			*[[Urothelial carcinoma]].
			*[[Malignant mesothelioma]].<ref name=pmid18318582>{{cite journal \|author=Marchevsky AM \|title=Application of immunohistochemistry to the diagnosis of malignant mesothelioma \|journal=Arch. Pathol. Lab. Med. \|volume=132 \|issue=3 \|pages=397-401 \|year=2008 \|month=March \|pmid=18318582 \|doi= \|url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=397}}</ref>

			==Negative==
			*[[Adenocarcinoma of the lung]].<ref name=pmid18318582>{{cite journal \|author=Marchevsky AM \|title=Application of immunohistochemistry to the diagnosis of malignant mesothelioma \|journal=Arch. Pathol. Lab. Med. \|volume=132 \|issue=3 \|pages=397-401 \|year=2008 \|month=March \|pmid=18318582 \|doi= \|url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=397}}</ref>

	==See also==		==See also==

Michael at 20:38, 5 May 2016

2016-05-05T20:38:08Z

← Older revision		Revision as of 20:38, 5 May 2016
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	'''Cytokeratin 5/6''', abbreviated '''CK/5/6''', is a common [[immunostain]].		'''Cytokeratin 5/6''', abbreviated '''CK/5/6''', is a common [[immunostain]].

			==Use==
			*Stain basal cells in prostate - useful for [[prostatic adenocarcinoma]] versus [[high-grade prostatic intraepithelial neoplasia]].

	==See also==		==See also==

Michael: create

2016-05-05T20:33:03Z

create

New page

'''Cytokeratin 5/6''', abbreviated '''CK/5/6''', is a common [[immunostain]].

==See also==
*[[Immunohistochemistry]].

[[Category:Immunohistochemistry]]