Cutaneous calcinosis - Revision history

Michael: /* See also */

2025-06-24T18:44:32Z

Michael: /* Micro */

2017-02-22T16:24:14Z

Micro

← Older revision		Revision as of 16:24, 22 February 2017
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	===Micro===		===Micro===
	The sections show ~~subcutaneous~~ calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying ~~skin~~ is unremarkable.		The sections show calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying epidermis is unremarkable.

	====Without epidermis====		====Without epidermis====

Michael: /* Micro */

2017-02-22T16:23:42Z

Micro

← Older revision		Revision as of 16:23, 22 February 2017
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	===Micro===		===Micro===
	The sections show subcutaneous calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying skin is unremarkable.		The sections show subcutaneous calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying skin is unremarkable.

			====Without epidermis====
			The sections show dermal/subcutaneous calcifications surrounded by fibrosis, macrophages and giant cells. No nuclear atypia is apparent. Overlying epidermis is absent.

	==See also==		==See also==

Michael: /* See also */

2016-04-05T22:14:13Z

Michael: /* See also */

2016-04-05T22:13:49Z

Michael at 22:13, 5 April 2016

2016-04-05T22:13:33Z

← Older revision		Revision as of 22:13, 5 April 2016
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	\| Width =		\| Width =
	\| Caption = Cutaneous calcinosis. [[H&E stain]].		\| Caption = Cutaneous calcinosis. [[H&E stain]].
	\| Synonyms = cutaneous calcification		\| Synonyms = cutaneous calcification, calcinosis cutis
	\| Micro = dermal calcification - usu. well-circumscribed		\| Micro = dermal calcification - usu. well-circumscribed
	\| Subtypes =		\| Subtypes =
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	\| Tx = excision		\| Tx = excision
	}}		}}
	'''Cutaneous calcinosis''', also '''calcinosis cutis''', is calcification of the [[skin]]. It is benign in itself; however, the underlying cause not be.		'''Cutaneous calcinosis''', also '''calcinosis cutis''' and '''cutaneous calcification''', is calcification of the [[skin]]. It is benign in itself; however, the underlying cause may ''not'' be.

	==General==		==General==

Michael at 22:12, 5 April 2016

2016-04-05T22:12:51Z

← Older revision		Revision as of 22:12, 5 April 2016
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	\| Width =		\| Width =
	\| Caption = Cutaneous calcinosis. [[H&E stain]].		\| Caption = Cutaneous calcinosis. [[H&E stain]].
	\| Synonyms =		\| Synonyms = cutaneous calcification
	\| Micro = dermal calcification - usu. well-circumscribed		\| Micro = dermal calcification - usu. well-circumscribed
	\| Subtypes =		\| Subtypes =

Michael at 13:21, 2 January 2014

2014-01-02T13:21:46Z

← Older revision		Revision as of 13:21, 2 January 2014
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	Subtypes:<ref name=emed>URL: [http://emedicine.medscape.com/article/1103137-overview http://emedicine.medscape.com/article/1103137-overview]. Accessed on: 21 September 2011.</ref>		Subtypes:<ref name=emed>URL: [http://emedicine.medscape.com/article/1103137-overview http://emedicine.medscape.com/article/1103137-overview]. Accessed on: 21 September 2011.</ref>
	#Dystrophic - due to death of cells; may be related to a tumour.		#Dystrophic - due to death of cells; may be related to a tumour.
	#Metastatic - due to chronic renal failure; hyperkalemia; paraneoplastic phenomenon.		#Metastatic - due to [[chronic renal failure]]; hyperkalemia; paraneoplastic phenomenon.
	#Iatrogenic - post surgical.		#Iatrogenic - post surgical.
	#Idiopathic.		#Idiopathic.

Michael: split out

2014-01-02T02:58:11Z

split out

← Older revision		Revision as of 02:58, 2 January 2014
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	#~~redirect~~ [[Non-~~malignant_skin_disease#Cutaneous_calcinosis~~]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Calcinosis cutis -- low mag.jpg
			\| Width =
			\| Caption = Cutaneous calcinosis. [[H&E stain]].
			\| Synonyms =
			\| Micro = dermal calcification - usu. well-circumscribed
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = firm nodule
			\| Grossing =
			\| Site = [[skin]], [[scrotum]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = +/-trauma at the site
			\| Signs = firm nodule
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx = excision
			}}
			'''Cutaneous calcinosis''', also '''calcinosis cutis''', is calcification of the [[skin]]. It is benign in itself; however, the underlying cause not be.

			==General==
			*Benign in itself; underlying cause may not be benign.
			*May be a [[scrotum\|scrotal]] lesion - known as ''scrotal calcinosis''.<ref name=pmid20178701>{{Cite journal \| last1 = Dubey \| first1 = S. \| last2 = Sharma \| first2 = R. \| last3 = Maheshwari \| first3 = V. \| title = Scrotal calcinosis: idiopathic or dystrophic? \| journal = Dermatol Online J \| volume = 16 \| issue = 2 \| pages = 5 \| month = \| year = 2010 \| doi = \| PMID = 20178701 }}</ref>

			Subtypes:<ref name=emed>URL: [http://emedicine.medscape.com/article/1103137-overview http://emedicine.medscape.com/article/1103137-overview]. Accessed on: 21 September 2011.</ref>
			#Dystrophic - due to death of cells; may be related to a tumour.
			#Metastatic - due to chronic renal failure; hyperkalemia; paraneoplastic phenomenon.
			#Iatrogenic - post surgical.
			#Idiopathic.

			==Gross==
			*Firm nodule.

			==Microscopic==
			Features:
			*Dermal calcification:
			**Acellular purple blobs on [[H&E]].
			***+/-Artefactual tearing of surrounding tissue due to processing (cutting).
			***+/-Small artefactual lines ~1-2 micrometers due to processing (cutting).
			***+/-Greyish rim of paucicellular material.
			**Usu. well-circumscribed.
			***May be surrounded by a palisading granuloma & [[giant cell]]s.

			===Images===
			<gallery>
			Image: Calcinosis cutis -- very low mag.jpg \| CC - very low mag.
			Image: Calcinosis cutis -- low mag.jpg \| CC - low mag.
			Image: Calcinosis cutis -- intermed mag.jpg \| CC - intermed. mag.
			</gallery>
			www:
			*[http://www.dermatopathonline.com/calcinosis%20cutis2.html Calcinosis cutis (dermatopathonline.com)].

			==Sign out==
			<pre>
			SKIN AND SUBCUTANEOUS LESION, LEFT HIP, EXCISION:
			- SUBCUTANEOUS CALCIFICATION SURROUNDED BY BENIGN FIBROUS TISSUE.
			- DERMAL SCAR.
			- NEGATIVE FOR MALIGNANCY.
			</pre>

			<pre>
			SUBCUTANEOUS MASS, OVER BURSA OF ELBOW, EXCISION:
			- CALCINOSIS CUTIS.
			</pre>

			===Micro===
			The sections show subcutaneous calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying skin is unremarkable.

			==See also==
			*[[Non-malignant skin disease]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Non-malignant skin disease]]

Michael: +cat.

2011-10-22T06:00:58Z

+cat.

← Older revision		Revision as of 06:00, 22 October 2011
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	#redirect [[Non-malignant_skin_disease#Cutaneous_calcinosis]]		#redirect [[Non-malignant_skin_disease#Cutaneous_calcinosis]]

			[[Category:Diagnosis]]

← Older revision		Revision as of 18:44, 24 June 2025
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	*[[Non-malignant skin disease]].		*[[Non-malignant skin disease]].
	*[[Heterotopic ossification]].		*[[Heterotopic ossification]].
			*[[Scrotolith]].

	==References==		==References==

← Older revision		Revision as of 22:14, 5 April 2016
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	==See also==		==See also==
	*[[Non-malignant skin disease]].		*[[Non-malignant skin disease]].
	*[[Heterotopic ~~calcification~~]].		*[[Heterotopic ossification]].

	==References==		==References==