Craniopharyngioma - Revision history

Jensflorian: The oldest specimen from 1828 is displayed in the pathological-anatomical museum of Vienna.

2019-10-11T11:56:43Z

The oldest specimen from 1828 is displayed in the pathological-anatomical museum of Vienna.

← Older revision		Revision as of 11:56, 11 October 2019
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	*Epidermoid		*Epidermoid
	*Well-differentiated carcinoma metastasis		*Well-differentiated carcinoma metastasis

			==Trivia==
			*The oldest specimen from 1828 is displayed in the pathological-anatomical museum of Vienna.<ref>{{Cite journal \| last1 = Pascual \| first1 = JM. \| last2 = Prieto \| first2 = R. \| last3 = Rosdolsky \| first3 = M. \| last4 = Hofecker \| first4 = V. \| last5 = Strauss \| first5 = S. \| last6 = Winter \| first6 = E. \| last7 = Ulrich \| first7 = W. \| title = Joseph Engel (1816-1899), author of a meaningful dissertation on tumors of the pituitary infundibulum: his report on the oldest preserved whole craniopharyngioma specimen. \| journal = Virchows Arch \| volume = \| issue = \| pages = \| month = Sep \| year = 2019 \| doi = 10.1007/s00428-019-02664-z \| PMID = 31511968 }}</ref>


	==See also==		==See also==

Jensflorian: typo

2019-10-11T11:49:52Z

typo

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	\| Tx =		\| Tx =
	}}		}}
	'''Craniopharyngioma''' is a benign ~~epitehlial~~ [[neuropathology tumour]].		'''Craniopharyngioma''' is a benign epithelial [[neuropathology tumour]].

	It is subdivided into '''papillary craniopharyngioma''' and '''adamantinomatous craniopharyngioma'''.		It is subdivided into '''papillary craniopharyngioma''' and '''adamantinomatous craniopharyngioma'''.

Jensflorian: Update

2019-10-11T11:49:11Z

Update

← Older revision		Revision as of 11:49, 11 October 2019
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	\| Tx =		\| Tx =
	}}		}}
	'''Craniopharyngioma''' is a benign [[neuropathology tumour]].		'''Craniopharyngioma''' is a benign epitehlial [[neuropathology tumour]].

	It is subdivided into '''papillary craniopharyngioma''' and '''adamantinomatous craniopharyngioma'''.		It is subdivided into '''papillary craniopharyngioma''' and '''adamantinomatous craniopharyngioma'''.

Jensflorian: /* Imaging */ update

2019-10-11T11:48:15Z

Imaging: update

← Older revision		Revision as of 11:48, 11 October 2019
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	==Imaging==		==Imaging==
			Radiology:<ref name=pmid17425791/>
	*Calcifications (adamantinous type).		*Calcifications (adamantinous type).
	*Contrast enhancing.		*Contrast enhancing.

Jensflorian: /* Gross */ update

2019-10-11T11:48:04Z

Gross: update

← Older revision		Revision as of 11:48, 11 October 2019
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	*Cystic mass filled with motor oil-like fluid.<ref name=pmid21584897>{{Cite journal \| last1 = Fernandez-Miranda \| first1 = JC. \| last2 = Gardner \| first2 = PA. \| last3 = Snyderman \| first3 = CH. \| last4 = Devaney \| first4 = KO. \| last5 = Strojan \| first5 = P. \| last6 = Suárez \| first6 = C. \| last7 = Genden \| first7 = EM. \| last8 = Rinaldo \| first8 = A. \| last9 = Ferlito \| first9 = A. \| title = Craniopharyngioma: a pathologic, clinical, and surgical review. \| journal = Head Neck \| volume = 34 \| issue = 7 \| pages = 1036-44 \| month = Jul \| year = 2012 \| doi = 10.1002/hed.21771 \| PMID = 21584897 }}</ref>		*Cystic mass filled with motor oil-like fluid.<ref name=pmid21584897>{{Cite journal \| last1 = Fernandez-Miranda \| first1 = JC. \| last2 = Gardner \| first2 = PA. \| last3 = Snyderman \| first3 = CH. \| last4 = Devaney \| first4 = KO. \| last5 = Strojan \| first5 = P. \| last6 = Suárez \| first6 = C. \| last7 = Genden \| first7 = EM. \| last8 = Rinaldo \| first8 = A. \| last9 = Ferlito \| first9 = A. \| title = Craniopharyngioma: a pathologic, clinical, and surgical review. \| journal = Head Neck \| volume = 34 \| issue = 7 \| pages = 1036-44 \| month = Jul \| year = 2012 \| doi = 10.1002/hed.21771 \| PMID = 21584897 }}</ref>
	**May not be seen in the papillary variant of craniopharyngioma.		**May not be seen in the papillary variant of craniopharyngioma.

	~~Radiology:<ref name=pmid17425791/>~~
	*Calcified - adamantinomatous type only.		*Calcified - adamantinomatous type only.
	*Solid & cystic.		*Solid & cystic.

Jensflorian: /* Inmaging */ typo

2019-10-11T11:47:26Z

Inmaging: typo

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	*More frequent in asia than in Europe/US.		*More frequent in asia than in Europe/US.

	==~~Inmaging~~==		==Imaging==
	*Calcifications (adamantinous type).		*Calcifications (adamantinous type).
	*Contrast enhancing.		*Contrast enhancing.

Jensflorian: /* General */ clinical data

2019-10-11T11:38:56Z

General: clinical data

← Older revision		Revision as of 11:38, 11 October 2019
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	* Typically contain BRAF V600E mutations.<ref name=pmid24413733>{{Cite journal \| last1 = Brastianos \| first1 = PK. \| last2 = Taylor-Weiner \| first2 = A. \| last3 = Manley \| first3 = PE. \| last4 = Jones \| first4 = RT. \| last5 = Dias-Santagata \| first5 = D. \| last6 = Thorner \| first6 = AR. \| last7 = Lawrence \| first7 = MS. \| last8 = Rodriguez \| first8 = FJ. \| last9 = Bernardo \| first9 = LA. \| title = Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. \| journal = Nat Genet \| volume = 46 \| issue = 2 \| pages = 161-5 \| month = Feb \| year = 2014 \| doi = 10.1038/ng.2868 \| PMID = 24413733 }}</ref>		* Typically contain BRAF V600E mutations.<ref name=pmid24413733>{{Cite journal \| last1 = Brastianos \| first1 = PK. \| last2 = Taylor-Weiner \| first2 = A. \| last3 = Manley \| first3 = PE. \| last4 = Jones \| first4 = RT. \| last5 = Dias-Santagata \| first5 = D. \| last6 = Thorner \| first6 = AR. \| last7 = Lawrence \| first7 = MS. \| last8 = Rodriguez \| first8 = FJ. \| last9 = Bernardo \| first9 = LA. \| title = Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. \| journal = Nat Genet \| volume = 46 \| issue = 2 \| pages = 161-5 \| month = Feb \| year = 2014 \| doi = 10.1038/ng.2868 \| PMID = 24413733 }}</ref>
	*Usually solid.		*Usually solid.

			==Clinical features==
			*Usu. located in the suprasellar cistern.
			**Rare locations: Cerebellopontine angle, sphenoid sinus, third ventricle.
			*Visual problems.
			*Endocrine deficiencies.
			*Hypothalamic dysfunction (obesity).
			*More frequent in asia than in Europe/US.

			==Inmaging==
			*Calcifications (adamantinous type).
			*Contrast enhancing.
			*Cystic portions.

	==Gross==		==Gross==

Jensflorian: cat

2015-07-18T11:54:45Z

cat

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	{{Reflist\|2}}		{{Reflist\|2}}

	[[Category:Neuropathology]]		[[Category:Neuropathology tumours]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:Papillary tumour]]		[[Category:Papillary tumour]]

Jensflorian: +cat

2015-04-29T09:39:08Z

+cat

← Older revision		Revision as of 09:39, 29 April 2015
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	[[Category:Neuropathology]]		[[Category:Neuropathology]]
			[[Category:Diagnosis]]
			[[Category:Papillary tumour]]

Michael: /* Adamantinomatous */

2015-04-11T07:06:03Z

Adamantinomatous

← Older revision		Revision as of 07:06, 11 April 2015
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	===Adamantinomatous===		===Adamantinomatous===
	Features (adamantinomatous):<ref name=Ref_DCHH184>{{Ref DCHH\|184}}</ref>		Features (adamantinomatous):<ref name=Ref_DCHH184>{{Ref DCHH\|184}}</ref>
	*~~trabecular~~ squamous epithelium bordered by palisaded ~~columar~~ epithelum.		*Trabecular squamous epithelium bordered by palisaded columnar epithelum.
	*Lobules with loosely distributed epithelia ("stellate reticulum").		*Lobules with loosely distributed epithelia ("stellate reticulum").
	*Well-circumscribed (or pseudoinvasive border).		*Well-circumscribed (or pseudoinvasive border).
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	*Bland nuclei (with occ. small nucleoli).		*Bland nuclei (with occ. small nucleoli).
	*"Wet" keratin - nests of whorled keratin.		*"Wet" keratin - nests of whorled keratin.
	*Calcifications (non-psammomatous).		*Calcifications (non-[[psammoma bodies\|psammomatous]]).

	====Images====		====Images====