Columnar cell change of the breast - Revision history

Michael at 21:08, 26 November 2021

2021-11-26T21:08:22Z

← Older revision		Revision as of 21:08, 26 November 2021
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			[[Image:Columnar cell change -- very high mag.jpg \|thumb\|right\|Columnar cell change of the breast - very high magnification. [[H&E stain]]. (WC/Nephron)]]
	'''Columnar cell change of the breast''', usually '''columnar cell change''' (abbreviated '''CCC'''), is a benign finding in [[breast pathology]].		'''Columnar cell change of the breast''', usually '''columnar cell change''' (abbreviated '''CCC'''), is a benign finding in [[breast pathology]].

Michael: /* Microscopic */

2016-07-01T04:51:51Z

Microscopic

← Older revision		Revision as of 04:51, 1 July 2016
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	**The snouts are attached to the cell-- appear as round ball only in the plane of section.		**The snouts are attached to the cell-- appear as round ball only in the plane of section.
	*Cytoplasm +/-eosinophilia.		*Cytoplasm +/-eosinophilia.
	*Often purple luminal calcifications		*Often (purple) luminal [[breast calcifications\|calcifications]].

	DDx:		DDx:
	*Flat epithelial atypia (>2 cell layers).{{Fact}}		*[[Flat epithelial atypia]] (>2 cell layers).{{Fact}}
	**If the columnar cells shows low to intermediate grade atypia the process is termed "flat epithelial atypia"		**If the columnar cells shows low to intermediate grade atypia the process is termed "flat epithelial atypia"
	**If higher grade ~~atyia~~ is present the lesion is termed "flat DCIS" (clinging carcinoma)		**If higher grade atypia is present the lesion is termed "flat DCIS" (clinging carcinoma).

	===Images===		===Images===

Michael: /* General */

2016-07-01T04:50:50Z

General

← Older revision		Revision as of 04:50, 1 July 2016
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	==General==		==General==
	*Columnar cell change is associated with (benign) [[breast calcification\|calcification]] - '''key point'''.		*Columnar cell change is associated with (benign) [[breast calcification\|calcification]]<ref name=pmid19089736>{{Cite journal \| last1 = Jara-Lazaro \| first1 = AR. \| last2 = Tse \| first2 = GM. \| last3 = Tan \| first3 = PH. \| title = Columnar cell lesions of the breast: an update and significance on core biopsy. \| journal = Pathology \| volume = 41 \| issue = 1 \| pages = 18-27 \| month = Jan \| year = 2009 \| doi = 10.1080/00313020802563486 \| PMID = 19089736 }}</ref> - '''key point'''.

	==Microscopic==		==Microscopic==

Michael: Created page with "'''Columnar cell change of the breast''', usually '''columnar cell change''' (abbreviated '''CCC'''), is a benign finding in breast pathology. It is also known as '''blun..."

2016-07-01T04:49:25Z

Created page with "'''Columnar cell change of the breast''', usually '''columnar cell change''' (abbreviated '''CCC'''), is a benign finding in breast pathology. It is also known as '''blun..."

New page

'''Columnar cell change of the breast''', usually '''columnar cell change''' (abbreviated '''CCC'''), is a benign finding in [[breast pathology]].

It is also known as '''blunt duct adenosis'''.

==General==
*Columnar cell change is associated with (benign) [[breast calcification|calcification]] - '''key point'''.

==Microscopic==
Features:
*Secretory cells (line gland lumen) have columnar morphology.
*May have "apical snouts".
**Blebs or round balls eosinophilic material appear to be adjacent to the cell at their luminal surface.
**The snouts are attached to the cell-- appear as round ball only in the plane of section.
*Cytoplasm +/-eosinophilia.
*Often purple luminal calcifications

DDx:
*Flat epithelial atypia (>2 cell layers).{{Fact}}
**If the columnar cells shows low to intermediate grade atypia the process is termed "flat epithelial atypia"
**If higher grade atyia is present the lesion is termed "flat DCIS" (clinging carcinoma)

===Images===
<gallery>
Image: Columnar cell change -- intermed mag.jpg | CCC - intermed. mag.
Image: Columnar cell change -- high mag.jpg | CCC - high mag.
Image: Columnar cell change -- very high mag.jpg | CCC - very high mag.
</gallery>
====www=====
*[http://webpathology.com/image.asp?case=652&n=1 Columnar cell change (webpathology.com)].

==Sign out==
*Usually not reported.

==See also==
*[[Breast pathology]].

==References==
{{Reflist|1}}

[[Category:Breast pathology]]
[[Category:Diagnosis]]