Collecting duct carcinoma - Revision history

Michael at 15:10, 20 March 2024

2024-03-20T15:10:52Z

← Older revision		Revision as of 15:10, 20 March 2024
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	\| Micro = tubular structures with tapered ends, [[hobnail pattern]], nuclear pleomorphism), high mitotic rate		\| Micro = tubular structures with tapered ends, [[hobnail pattern]], nuclear pleomorphism), high mitotic rate
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[papillary renal cell carcinoma]] ~~(type 2)~~, [[urothelial carcinoma]] (with glandular differentiation), metastatic [[adenocarcinoma]], [[renal medullary carcinoma]]		\| LMDDx = [[papillary renal cell carcinoma]], [[urothelial carcinoma]] (with glandular differentiation), metastatic [[adenocarcinoma]], [[renal medullary carcinoma]], [[ALK-rearranged renal cell carcinoma]]
	\| Stains =		\| Stains =
	\| IHC = CD117 +ve, CK7 +ve, PAX8 +ve, CD10 -ve, AMACR -ve, p63 -ve		\| IHC = CD117 +ve, CK7 +ve, PAX8 +ve, CD10 -ve, AMACR -ve, p63 -ve
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	DDx:		DDx:
	*[[Papillary renal cell carcinoma]] ~~- type 2~~.		*[[Papillary renal cell carcinoma]].
	*[[Urothelial carcinoma]] with glandular differentiation.		*[[Urothelial carcinoma]] with glandular differentiation.
	*Metastatic [[adenocarcinoma]].		*Metastatic [[adenocarcinoma]].

Michael: /* IHC */

2017-03-05T17:29:03Z

IHC

← Older revision		Revision as of 17:29, 5 March 2017
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	*CD10 -ve.		*CD10 -ve.
	*AMACR -ve.		*AMACR -ve.
			*[[PAX8]] +ve.<ref name=pmid20463571>{{Cite journal \| last1 = Albadine \| first1 = R. \| last2 = Schultz \| first2 = L. \| last3 = Illei \| first3 = P. \| last4 = Ertoy \| first4 = D. \| last5 = Hicks \| first5 = J. \| last6 = Sharma \| first6 = R. \| last7 = Epstein \| first7 = JI. \| last8 = Netto \| first8 = GJ. \| title = PAX8 (+)/p63 (-) immunostaining pattern in renal collecting duct carcinoma (CDC): a useful immunoprofile in the differential diagnosis of CDC versus urothelial carcinoma of upper urinary tract. \| journal = Am J Surg Pathol \| volume = 34 \| issue = 7 \| pages = 965-9 \| month = Jul \| year = 2010 \| doi = 10.1097/PAS.0b013e3181dc5e8a \| PMID = 20463571 }}</ref>

	UCC:		UCC:

Michael: /* Images */ +another

2016-10-17T01:17:40Z

Images: +another

← Older revision		Revision as of 01:17, 17 October 2016
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	<gallery>		<gallery>
	Image: Collecting duct carcinoma - 1 WBAL.tif \| CDC - 1 (WC/Netto)		Image: Collecting duct carcinoma - 1 WBAL.tif \| CDC - 1 (WC/Netto)
	Image: Collecting duct carcinoma - 2 WBAL.tif \| ~~CDD~~ - 2 (WC/Netto)		Image: Collecting duct carcinoma - 2 WBAL.tif \| CDC - 2 (WC/Netto)
			Image: Collecting duct carcinoma - 5 WBAL.tif \| CDC - 5 (WC/Netto)
	</gallery>		</gallery>
	====www====		====www====

Michael: /* www */ fix link, remove dead links

2016-10-17T00:09:52Z

www: fix link, remove dead links

← Older revision		Revision as of 00:09, 17 October 2016
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	</gallery>		</gallery>
	====www====		====www====
	*[http://~~webpathology~~.~~com~~/~~image~~.~~asp~~?~~case~~=~~69&n=1 CDC (webpathology.com)].~~		*[http://images.rsna.org/index.html?doi=10.1148/rg.266065010&fig=F17 CDC (rsna.org)].<ref name=pmid17102051>{{Cite journal \| last1 = Prasad \| first1 = SR. \| last2 = Humphrey \| first2 = PA. \| last3 = Catena \| first3 = JR. \| last4 = Narra \| first4 = VR. \| last5 = Srigley \| first5 = JR. \| last6 = Cortez \| first6 = AD. \| last7 = Dalrymple \| first7 = NC. \| last8 = Chintapalli \| first8 = KN. \| title = Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation. \| journal = Radiographics \| volume = 26 \| issue = 6 \| pages = 1795-806; discussion 1806-10 \| month = \| year = \| doi = 10.1148/rg.266065010 \| PMID = 17102051 }}</ref>
	*[http://webpathology.~~com~~/~~image~~.~~asp?n=2~~&~~Case~~=~~69 CDC - showing hobnail pattern (webpathology.com)].~~
	*[http://radiographics.rsna.org/content/26/6/1795/F17~~.expansion.html~~ CDC (rsna.org)].<ref name=pmid17102051>{{Cite journal \| last1 = Prasad \| first1 = SR. \| last2 = Humphrey \| first2 = PA. \| last3 = Catena \| first3 = JR. \| last4 = Narra \| first4 = VR. \| last5 = Srigley \| first5 = JR. \| last6 = Cortez \| first6 = AD. \| last7 = Dalrymple \| first7 = NC. \| last8 = Chintapalli \| first8 = KN. \| title = Common and uncommon histologic subtypes of renal cell carcinoma: imaging spectrum with pathologic correlation. \| journal = Radiographics \| volume = 26 \| issue = 6 \| pages = 1795-806; discussion 1806-10 \| month = \| year = \| doi = 10.1148/rg.266065010 \| PMID = 17102051 }}</ref>

	==IHC==		==IHC==

Michael: /* Images */

2016-10-17T00:01:18Z

Images

← Older revision		Revision as of 00:01, 17 October 2016
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	Image: Collecting duct carcinoma - 1 WBAL.tif \| CDC - 1 (WC/Netto)		Image: Collecting duct carcinoma - 1 WBAL.tif \| CDC - 1 (WC/Netto)
	Image: Collecting duct carcinoma - 2 WBAL.tif \| CDD - 2 (WC/Netto)		Image: Collecting duct carcinoma - 2 WBAL.tif \| CDD - 2 (WC/Netto)
	<gallery>		</gallery>
	====www====		====www====
	*[http://webpathology.com/image.asp?case=69&n=1 CDC (webpathology.com)].		*[http://webpathology.com/image.asp?case=69&n=1 CDC (webpathology.com)].

Michael: +images

2016-10-17T00:00:44Z

+images

← Older revision		Revision as of 00:00, 17 October 2016
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Collecting duct carcinoma - 2 WBAL.tif
	\| Width =		\| Width =
	\| Caption =		\| Caption = Collecting duct carcinoma. (WC/George Netto)
	\| Micro = tubular structures with tapered ends, [[hobnail pattern]], nuclear pleomorphism), high mitotic rate		\| Micro = tubular structures with tapered ends, [[hobnail pattern]], nuclear pleomorphism), high mitotic rate
	\| Subtypes =		\| Subtypes =
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	===Images===		===Images===
	www:		<gallery>
			Image: Collecting duct carcinoma - 1 WBAL.tif \| CDC - 1 (WC/Netto)
			Image: Collecting duct carcinoma - 2 WBAL.tif \| CDD - 2 (WC/Netto)
			<gallery>
			====www====
	*[http://webpathology.com/image.asp?case=69&n=1 CDC (webpathology.com)].		*[http://webpathology.com/image.asp?case=69&n=1 CDC (webpathology.com)].
	*[http://webpathology.com/image.asp?n=2&Case=69 CDC - showing hobnail pattern (webpathology.com)].		*[http://webpathology.com/image.asp?n=2&Case=69 CDC - showing hobnail pattern (webpathology.com)].

Michael: /* Microscopic */

2016-03-16T03:56:34Z

Microscopic

← Older revision		Revision as of 03:56, 16 March 2016
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	*Metastatic [[adenocarcinoma]].		*Metastatic [[adenocarcinoma]].
	*[[Renal medullary carcinoma]] - typically younger, sickle cell trait.		*[[Renal medullary carcinoma]] - typically younger, sickle cell trait.
			*[[Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma]].

	===Images===		===Images===

Michael at 03:32, 18 November 2015

2015-11-18T03:32:14Z

← Older revision		Revision as of 03:32, 18 November 2015
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross = medullary tumour
	\| Grossing =		\| Grossing = [[total nephrectomy for tumour grossing]], [[partial nephrectomy grossing]]
			\| Staging = [[kidney cancer staging]]
	\| Site = [[kidney]] - see [[kidney tumours]]		\| Site = [[kidney]] - see [[kidney tumours]]
	\| Assdx =		\| Assdx =
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	*Typically young adults.		*Typically young adults.

			==Gross==
			*Medullary location - as opposed to cortical.<ref>{{Cite journal \| last1 = López \| first1 = JI. \| last2 = Larrinaga \| first2 = G. \| last3 = Kuroda \| first3 = N. \| last4 = Angulo \| first4 = JC. \| title = The normal and pathologic renal medulla: a comprehensive overview. \| journal = Pathol Res Pract \| volume = 211 \| issue = 4 \| pages = 271-80 \| month = Apr \| year = 2015 \| doi = 10.1016/j.prp.2014.12.009 \| PMID = 25595996 }}</ref>
	==Microscopic==		==Microscopic==
	Features:<ref name=Ref_GUP295>{{Ref GUP\|295}}</ref>		Features:<ref name=Ref_GUP295>{{Ref GUP\|295}}</ref>

Michael: /* IHC */

2014-10-20T14:41:37Z

IHC

← Older revision		Revision as of 14:41, 20 October 2014
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	Others:		Others:
	*CK7 +ve.<ref name=pmid12613443>{{Cite journal \| last1 = Kim \| first1 = MK. \| last2 = Kim \| first2 = S. \| title = Immunohistochemical profile of common epithelial neoplasms arising in the kidney. \| journal = Appl Immunohistochem Mol Morphol \| volume = 10 \| issue = 4 \| pages = 332-8 \| month = Dec \| year = 2002 \| doi = \| PMID = 12613443 }}</ref>		*CK7 +ve.<ref name=pmid12613443>{{Cite journal \| last1 = Kim \| first1 = MK. \| last2 = Kim \| first2 = S. \| title = Immunohistochemical profile of common epithelial neoplasms arising in the kidney. \| journal = Appl Immunohistochem Mol Morphol \| volume = 10 \| issue = 4 \| pages = 332-8 \| month = Dec \| year = 2002 \| doi = \| PMID = 12613443 }}</ref>
			*UEA-1 +ve.
			**-ve in [[HLRCC]].<ref name=pmid17895761>{{Cite journal \| last1 = Merino \| first1 = MJ. \| last2 = Torres-Cabala \| first2 = C. \| last3 = Pinto \| first3 = P. \| last4 = Linehan \| first4 = WM. \| title = The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome. \| journal = Am J Surg Pathol \| volume = 31 \| issue = 10 \| pages = 1578-85 \| month = Oct \| year = 2007 \| doi = 10.1097/PAS.0b013e31804375b8 \| PMID = 17895761 }}</ref>

	==See also==		==See also==

Michael at 21:30, 22 August 2014

2014-08-22T21:30:16Z

← Older revision		Revision as of 21:30, 22 August 2014
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	}}		}}
	'''Collecting duct carcinoma''', also known as '''Bellini duct carcinoma'''<ref name=pmid21393935>{{Cite journal \| last1 = Stamatiou \| first1 = K. \| last2 = Zizi-Sermpetzoglou \| first2 = A. \| title = Bellini duct carcinoma accidentally found upon investigation of uric acid lithiasis. \| journal = Indian J Pathol Microbiol \| volume = 54 \| issue = 1 \| pages = 229-30 \| month = \| year = \| doi = 10.4103/0377-4929.77425 \| PMID = 21393935 }}</ref> and '''carcinoma of the collecting ducts of Bellini''', is a rare aggressive [[kidney tumour]].		'''Collecting duct carcinoma''', also known as '''Bellini duct carcinoma'''<ref name=pmid21393935>{{Cite journal \| last1 = Stamatiou \| first1 = K. \| last2 = Zizi-Sermpetzoglou \| first2 = A. \| title = Bellini duct carcinoma accidentally found upon investigation of uric acid lithiasis. \| journal = Indian J Pathol Microbiol \| volume = 54 \| issue = 1 \| pages = 229-30 \| month = \| year = \| doi = 10.4103/0377-4929.77425 \| PMID = 21393935 }}</ref> and '''carcinoma of the collecting ducts of Bellini''', is a rare aggressive [[kidney tumour]].

			It should '''not''' be confused with [[tubulocystic carcinoma of the kidney]] (also known as ''low-grade collecting duct carcinoma'').

	==General==		==General==