Chorioamnionitis - Revision history

Michael: /* Microscopic */

2014-06-25T12:09:32Z

Microscopic

← Older revision		Revision as of 12:09, 25 June 2014
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	DDx:		DDx:
	*[[Membranitis]].		*[[Membranitis]].
	*[[Placental meconium]].		*[[Placental meconium]] - associated with degeneration (apoptotic cells).
	*Intramembrane bleed - rare [[neutrophil]]s with [[red blood cell]]s in the amnion without significant neutrophils in the chorion and decidua.		*Intramembrane bleed - rare [[neutrophil]]s with [[red blood cell]]s in the amnion without significant neutrophils in the chorion and decidua.

Michael: /* Sign out */

2014-01-23T14:17:00Z

Sign out

← Older revision		Revision as of 14:17, 23 January 2014
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	</pre>		</pre>

	===Chorioamnionitis ~~and~~ funisitis===		===Chorioamnionitis with vasculitis===
			<pre>
			PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:
			- CHORIOAMNIONITIS, MODERATE.
			- THREE VESSEL UMBILICAL CORD WITH VASCULITIS, EARLY.
			- FETAL MEMBRANES NEGATIVE FOR MECONIUM.
			- PLACENTAL DISC WITH THIRD TRIMESTER VILLI.
			</pre>

			===Chorioamnionitis with funisitis===
	<pre>		<pre>
	PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:		PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:

Michael at 13:52, 23 January 2014

2014-01-23T13:52:52Z

← Older revision		Revision as of 13:52, 23 January 2014
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	\| Prognosis = good		\| Prognosis = good
	\| Other =		\| Other =
	\| ClinDDx =		\| ClinDDx = other causes of maternal fever and fetal tachycardia
			\| Tx = antibiotics
	}}		}}
	'''Chorioamnionitis''' is a common pathology of the [[placenta]].		'''Chorioamnionitis''' is a common pathology of the [[placenta]].
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	*Neutrophils in the amnion.		*Neutrophils in the amnion.
	**Amnion:		**Amnion:
	***The simple cuboidal epithelium and the paucicellular underlying connective tissue		***The simple cuboidal epithelium and the paucicellular underlying connective tissue.
	***Separated from the chorion by an artefactual cleft.		***Separated from the chorion by an artefactual cleft.
	*+/-Microorganisms (e.g. cocci<ref>{{Cite journal \| last1 = Murdoch \| first1 = DA. \| title = Gram-positive anaerobic cocci. \| journal = Clin Microbiol Rev \| volume = 11 \| issue = 1 \| pages = 81-120 \| month = Jan \| year = 1998 \| doi = \| PMID = 9457430 \| PMC = 121377}}		*+/-Microorganisms (e.g. cocci<ref>{{Cite journal \| last1 = Murdoch \| first1 = DA. \| title = Gram-positive anaerobic cocci. \| journal = Clin Microbiol Rev \| volume = 11 \| issue = 1 \| pages = 81-120 \| month = Jan \| year = 1998 \| doi = \| PMID = 9457430 \| PMC = 121377}}

Michael: /* Microscopic */

2014-01-23T13:49:47Z

Microscopic

← Older revision		Revision as of 13:49, 23 January 2014
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	*[[Membranitis]].		*[[Membranitis]].
	*[[Placental meconium]].		*[[Placental meconium]].
			*Intramembrane bleed - rare [[neutrophil]]s with [[red blood cell]]s in the amnion without significant neutrophils in the chorion and decidua.

	===Images===		===Images===

Michael: /* Microscopic */ more

2013-10-19T12:57:38Z

Microscopic: more

← Older revision		Revision as of 12:57, 19 October 2013
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	Note:		Note:
	*Severe cases may have [[umbilical cord vasculitis]] or [[funisitis]].		*Severe cases may have [[umbilical cord vasculitis]] or [[funisitis]].

			DDx:
			*[[Membranitis]].
			*[[Placental meconium]].

	===Images===		===Images===

Michael: more

2013-10-07T03:34:32Z

← Older revision		Revision as of 03:34, 7 October 2013
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	\| Grossing =		\| Grossing =
	\| Site = [[placenta]]		\| Site = [[placenta]]
	\| Assdx = [[umbilical cord vasculitis]], [[funisitis]]		\| Assdx = [[umbilical cord vasculitis]], [[funisitis]], [[placental meconium]]
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx = +/-premature rupture of membranes, +/-preterm labour, +/-failure to progress		\| Clinicalhx = +/-premature rupture of membranes, +/-preterm labour, +/-failure to progress

Michael: tweak

2013-09-27T12:05:46Z

tweak

← Older revision		Revision as of 12:05, 27 September 2013
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	\| Width =		\| Width =
	\| Caption = Chorioamnionitis. [[H&E stain]].		\| Caption = Chorioamnionitis. [[H&E stain]].
	\| Micro =		\| Micro = [[neutrophil]]s present in the amnion, usu. associated with abundant subchorionic neutrophils
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx = [[membranitis]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross = +/-opaque membranes
	\| Grossing =		\| Grossing =
	\| Site = [[placenta]]		\| Site = [[placenta]]
	\| Assdx = [[funisitis]]		\| Assdx = [[umbilical cord vasculitis]], [[funisitis]]
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx =		\| Clinicalhx = +/-premature rupture of membranes, +/-preterm labour, +/-failure to progress
	\| Signs = fetal tachycardia, maternal fever		\| Signs = fetal tachycardia, maternal fever, nonreassuring fetal heart rate
	\| Symptoms =		\| Symptoms =
	\| Prevalence = common		\| Prevalence = common
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	Note:		Note:
	*Severe cases may have umbilical cord vasculitis or [[funisitis]].		*Severe cases may have [[umbilical cord vasculitis]] or [[funisitis]].

	===Images===		===Images===

Michael: split-out

2013-09-27T11:59:51Z

split-out

← Older revision		Revision as of 11:59, 27 September 2013
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	#~~redirect~~ [[Placenta~~#Chorioamnionitis~~]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Chorioamnionitis_-2-_very_high_mag.jpg
			\| Width =
			\| Caption = Chorioamnionitis. [[H&E stain]].
			\| Micro =
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[placenta]]
			\| Assdx = [[funisitis]]
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = fetal tachycardia, maternal fever
			\| Symptoms =
			\| Prevalence = common
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = good
			\| Other =
			\| ClinDDx =
			}}
			'''Chorioamnionitis''' is a common pathology of the [[placenta]].

			==General==
			*Associated with pre-term labour.<ref name=pmid22958008>{{Cite journal \| last1 = Martinelli \| first1 = P. \| last2 = Sarno \| first2 = L. \| last3 = Maruotti \| first3 = GM. \| last4 = Paludetto \| first4 = R. \| title = Chorioamnionitis and prematurity: a critical review. \| journal = J Matern Fetal Neonatal Med \| volume = 25 Suppl 4 \| issue = \| pages = 29-31 \| month = Oct \| year = 2012 \| doi = 10.3109/14767058.2012.714981 \| PMID = 22958008 }}</ref>
			**Classically described as due to an ascending infection.
			*At term usually non-infectious.<ref name=pmid22412842>{{Cite journal \| last1 = Roberts \| first1 = DJ. \| last2 = Celi \| first2 = AC. \| last3 = Riley \| first3 = LE. \| last4 = Onderdonk \| first4 = AB. \| last5 = Boyd \| first5 = TK. \| last6 = Johnson \| first6 = LC. \| last7 = Lieberman \| first7 = E. \| title = Acute histologic chorioamnionitis at term: nearly always noninfectious. \| journal = PLoS One \| volume = 7 \| issue = 3 \| pages = e31819 \| month = \| year = 2012 \| doi = 10.1371/journal.pone.0031819 \| PMID = 22412842 }}</ref>

			Clinical features:
			*Maternal fever.
			*Premature rupture of membranes (PROM).
			*Non-reassuring fetal heart rate (NRFHR).

			Management:
			*Antibiotics - usually ampicillin and gentamicin.<ref name=pmid20569811>{{Cite journal \| last1 = Tita \| first1 = AT. \| last2 = Andrews \| first2 = WW. \| title = Diagnosis and management of clinical chorioamnionitis. \| journal = Clin Perinatol \| volume = 37 \| issue = 2 \| pages = 339-54 \| month = Jun \| year = 2010 \| doi = 10.1016/j.clp.2010.02.003 \| PMID = 20569811 \| PMC = 3008318 }}</ref>

			==Gross==
			*Fetal membranes dull/opaque.

			==Microscopic==
			Features:
			*Neutrophils in the amnion.
			**Amnion:
			***The simple cuboidal epithelium and the paucicellular underlying connective tissue
			***Separated from the chorion by an artefactual cleft.
			*+/-Microorganisms (e.g. cocci<ref>{{Cite journal \| last1 = Murdoch \| first1 = DA. \| title = Gram-positive anaerobic cocci. \| journal = Clin Microbiol Rev \| volume = 11 \| issue = 1 \| pages = 81-120 \| month = Jan \| year = 1998 \| doi = \| PMID = 9457430 \| PMC = 121377}}
			</ref>) - very uncommon to see.

			Note:
			*Severe cases may have umbilical cord vasculitis or [[funisitis]].

			===Images===
			<gallery>
			Image:Chorioamnionitis_-_low_mag.jpg \| Chorioamnionitis - low mag. (WC)
			Image:Chorioamnionitis_-_high_mag.jpg \| Chorioamnionitis - high mag. (WC)
			Image:Chorioamnionitis_-2-_very_high_mag.jpg \| Chorioamnionitis - very high mag. (WC)
			</gallery>
			===Grading chorioamnionitis===
			Chorioamnionitis:<ref name=Ref_Sternberg4_2311>{{Ref Sternberg4\|2311}}</ref>
			# placental chorionic plate only.
			# 1 + subamniotic tissue.
			# 1 or 2 + necrosis ''or'' abscess.

			==Sign out==
			<pre>
			PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAREAN SECTION:
			- CHORIOAMNIONITIS.
			- FETAL MEMBRANES NEGATIVE FOR MECONIUM.
			- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS.
			- PLACENTAL DISC WITH THIRD TRIMESTER VILLI.
			- THROMBUS OF THE PLACENTAL DISC (1.3 CM - MAXIMAL DIMENSION).
			</pre>

			===Chorioamnionitis and funisitis===
			<pre>
			PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION:
			- CHORIOAMNIONITIS, MODERATE.
			- THREE VESSEL UMBILICAL CORD WITH FUNISITIS, MILD.
			- FETAL MEMBRANES NEGATIVE FOR MECONIUM.
			- PLACENTAL DISC WITH THIRD TRIMESTER VILLI.
			- THROMBUS OF THE PLACENTAL DISC (1.3 CM - MAXIMAL DIMENSION).
			</pre>

			==See also==
			*[[Membranitis]].
			*[[Funisitis]].
			*[[Placenta]].
			*[[Meconium]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Placenta]]

Michael: redirect

2012-01-05T02:46:13Z

redirect

New page

#redirect [[Placenta#Chorioamnionitis]]

[[Category:Diagnosis]]