Chagas disease - Revision history

Michael at 00:45, 2 March 2014

2014-03-02T00:45:37Z

← Older revision		Revision as of 00:45, 2 March 2014
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	*[[cardiac arrhythmia\|Arrhythmia]]s (late).		*[[cardiac arrhythmia\|Arrhythmia]]s (late).
	*[[Toxic megacolon]].<ref name=pmid1467905>{{Cite journal \| last1 = Kobayasi \| first1 = S. \| last2 = Mendes \| first2 = EF. \| last3 = Rodrigues \| first3 = MA. \| last4 = Franco \| first4 = MF. \| title = Toxic dilatation of the colon in Chagas' disease. \| journal = Br J Surg \| volume = 79 \| issue = 11 \| pages = 1202-3 \| month = Nov \| year = 1992 \| doi = \| PMID = 1467905 }}</ref>		*[[Toxic megacolon]].<ref name=pmid1467905>{{Cite journal \| last1 = Kobayasi \| first1 = S. \| last2 = Mendes \| first2 = EF. \| last3 = Rodrigues \| first3 = MA. \| last4 = Franco \| first4 = MF. \| title = Toxic dilatation of the colon in Chagas' disease. \| journal = Br J Surg \| volume = 79 \| issue = 11 \| pages = 1202-3 \| month = Nov \| year = 1992 \| doi = \| PMID = 1467905 }}</ref>
			*Chagas disease esophagopathy.<ref>{{Cite journal \| last1 = Vicentine \| first1 = FP. \| last2 = Herbella \| first2 = FA. \| last3 = Allaix \| first3 = ME. \| last4 = Silva \| first4 = LC. \| last5 = Patti \| first5 = MG. \| title = Comparison of idiopathic achalasia and Chagas' disease esophagopathy at the light of high-resolution manometry. \| journal = Dis Esophagus \| volume = 27 \| issue = 2 \| pages = 128-33 \| month = Feb \| year = 2014 \| doi = 10.1111/dote.12098 \| PMID = 23795824 }}</ref>
			**[[Achalasia]]-like pathology with dilation of the esophagus.

	Dx:<ref>URL: [http://www.cdc.gov/parasites/chagas/diagnosis.html http://www.cdc.gov/parasites/chagas/diagnosis.html]. Accessed on: 4 December 2011.</ref>		Dx:<ref>URL: [http://www.cdc.gov/parasites/chagas/diagnosis.html http://www.cdc.gov/parasites/chagas/diagnosis.html]. Accessed on: 4 December 2011.</ref>

Michael: w

2014-03-02T00:25:55Z

← Older revision		Revision as of 00:25, 2 March 2014
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	*Depends on phase of infection.		*Depends on phase of infection.
	*[[cardiac arrhythmia\|Arrhythmia]]s (late).		*[[cardiac arrhythmia\|Arrhythmia]]s (late).
	*Toxic megacolon.<ref name=pmid1467905>{{Cite journal \| last1 = Kobayasi \| first1 = S. \| last2 = Mendes \| first2 = EF. \| last3 = Rodrigues \| first3 = MA. \| last4 = Franco \| first4 = MF. \| title = Toxic dilatation of the colon in Chagas' disease. \| journal = Br J Surg \| volume = 79 \| issue = 11 \| pages = 1202-3 \| month = Nov \| year = 1992 \| doi = \| PMID = 1467905 }}</ref>		*[[Toxic megacolon]].<ref name=pmid1467905>{{Cite journal \| last1 = Kobayasi \| first1 = S. \| last2 = Mendes \| first2 = EF. \| last3 = Rodrigues \| first3 = MA. \| last4 = Franco \| first4 = MF. \| title = Toxic dilatation of the colon in Chagas' disease. \| journal = Br J Surg \| volume = 79 \| issue = 11 \| pages = 1202-3 \| month = Nov \| year = 1992 \| doi = \| PMID = 1467905 }}</ref>

	Dx:<ref>URL: [http://www.cdc.gov/parasites/chagas/diagnosis.html http://www.cdc.gov/parasites/chagas/diagnosis.html]. Accessed on: 4 December 2011.</ref>		Dx:<ref>URL: [http://www.cdc.gov/parasites/chagas/diagnosis.html http://www.cdc.gov/parasites/chagas/diagnosis.html]. Accessed on: 4 December 2011.</ref>

Michael: split out

2014-03-02T00:23:32Z

split out

← Older revision		Revision as of 00:23, 2 March 2014
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	~~#redirect [[Heart#Chagas_disease]]~~		'''Chagas disease''', also known as '''American trypanosomiasis''', is an infectious disease that affect various organs.

			==General==
			*Essentially a South American disease.
			*Etiology: protozoa ''Trypanosoma cruzi'' - transmitted by ''reduvid bugs'',<ref name=PMH0002348>URL: [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002348/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002348/]. Accessed on: 4 December 2011.</ref> also known as ''kissing bug''.<ref>URL: [http://www.who.int/topics/chagas_disease/en/ http://www.who.int/topics/chagas_disease/en/]. Accessed on: 1 December 2011.</ref>

			Clinical:<ref name=pmid17072450>{{Cite journal \| last1 = Teixeira \| first1 = AR. \| last2 = Nascimento \| first2 = RJ. \| last3 = Sturm \| first3 = NR. \| title = Evolution and pathology in chagas disease--a review. \| journal = Mem Inst Oswaldo Cruz \| volume = 101 \| issue = 5 \| pages = 463-91 \| month = Aug \| year = 2006 \| doi = \| PMID = 17072450 \|URL = http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000500001&lng=en&nrm=iso&tlng=en }}</ref>
			*Depends on phase of infection.
			*[[cardiac arrhythmia\|Arrhythmia]]s (late).
			*Toxic megacolon.<ref name=pmid1467905>{{Cite journal \| last1 = Kobayasi \| first1 = S. \| last2 = Mendes \| first2 = EF. \| last3 = Rodrigues \| first3 = MA. \| last4 = Franco \| first4 = MF. \| title = Toxic dilatation of the colon in Chagas' disease. \| journal = Br J Surg \| volume = 79 \| issue = 11 \| pages = 1202-3 \| month = Nov \| year = 1992 \| doi = \| PMID = 1467905 }}</ref>

			Dx:<ref>URL: [http://www.cdc.gov/parasites/chagas/diagnosis.html http://www.cdc.gov/parasites/chagas/diagnosis.html]. Accessed on: 4 December 2011.</ref>
			*Usually serology.
			*Thin blood smear.

			Tx:
			*Antimicrobials: benznidazole, nifurtimox.<ref name=PMH0002348/>

			==Microscopic==
			Features - heart:
			*Inflammation - main finding.<ref name=pmid17072450/>
			*Intramuscular organisms (without an inflammatory response).
			*Neuronal loss in atrial ganglia.<ref name=pmid17339569/>

			DDx:
			*[[Toxoplasmosis]].<ref>URL: [http://path.upmc.edu/cases/case160/micro.html http://path.upmc.edu/cases/case160/micro.html]. Accessed on: 8 January 2012.</ref> (???)

			Images:
			*[http://www.uaz.edu.mx/histo/pathology/ed/ch_9c/c9c_chagas.htm Chagas disease (uaz.edu.mx)].
			*[http://cardiovascres.oxfordjournals.org/content/60/1/96/F1.expansion.html Chagas disease (oxfordjournals.org)].<ref>{{Cite journal \| last1 = Higuchi \| first1 = Mde L. \| last2 = Benvenuti \| first2 = LA. \| last3 = Martins Reis \| first3 = M. \| last4 = Metzger \| first4 = M. \| title = Pathophysiology of the heart in Chagas' disease: current status and new developments. \| journal = Cardiovasc Res \| volume = 60 \| issue = 1 \| pages = 96-107 \| month = Oct \| year = 2003 \| doi = \| PMID = 14522411 }}</ref>

			==IHC==
			*Anti–T cruzi immunoperoxidase.<ref name=pmid17339569>{{Cite journal \| last1 = Marin-Neto \| first1 = JA. \| last2 = Cunha-Neto \| first2 = E. \| last3 = Maciel \| first3 = BC. \| last4 = Simões \| first4 = MV. \| title = Pathogenesis of chronic Chagas heart disease. \| journal = Circulation \| volume = 115 \| issue = 9 \| pages = 1109-23 \| month = Mar \| year = 2007 \| doi = 10.1161/CIRCULATIONAHA.106.624296 \| PMID = 17339569 \|URL = http://circ.ahajournals.org/content/115/9/1109.long }}</ref>

			==See also==
			*[[Heart]].

			==References==
			{{Reflist\|2}}

			[[Category:Heart]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: redirect w/ cat.

2011-12-04T18:06:34Z

redirect w/ cat.

New page

#redirect [[Heart#Chagas_disease]]

[[Category:Diagnosis]]