Case 84 - Revision history

Michael at 04:00, 29 September 2015

2015-09-29T04:00:47Z

← Older revision		Revision as of 04:00, 29 September 2015
Line 278:		Line 278:
	[[Category:Cases]]		[[Category:Cases]]

	~~<!-- SELECT A CATEGORY~~
	[[Category:Cases in genitourinary pathology]]		[[Category:Cases in genitourinary pathology]]
	-->		[[Category:Cases in genitourinary pathology - senior]]

	[[Category:Cases difficulty 4]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->		[[Category:Cases difficulty 4]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->

Rudolf: /* Diagnosis */

2015-09-19T22:10:27Z

Diagnosis

← Older revision		Revision as of 22:10, 19 September 2015
Line 268:		Line 268:

	===Diagnosis===		===Diagnosis===
	{{hidden\|Diagnosis\|<center>~~DIAGNOSIS GOES HERE~~</center>}}		{{hidden\|Diagnosis\|<center>[[sarcomatoid prostate carcinoma]]</center>}}
	<br>		<br>

	===Other cases===		===Other cases===
	{{Cases navigation}}		{{Cases navigation}}

Michael: /* IHC */

2015-09-19T22:07:12Z

IHC

← Older revision		Revision as of 22:07, 19 September 2015
Line 78:		Line 78:
	\| alk1=		\| alk1=
	\| amacr=		\| amacr=
	\| ar=		\| ar=
			\| atrx=
	\| b2microglobulin=		\| b2microglobulin=
	\| b72_3=		\| b72_3=
Line 86:		Line 87:
	\| bclxl=		\| bclxl=
	\| c3=		\| c3=
			\| ca9=
	\| calcitonin=		\| calcitonin=
	\| calponin=		\| calponin=
	\| calretinin=		\| calretinin=
	\| cam5p2=		\| cam5p2=
			\| cathepsink=
	\| cd10=		\| cd10=
	\| cd117=		\| cd117=
Line 105:		Line 108:
	\| cd4=		\| cd4=
	\| cd43=		\| cd43=
	~~\| cd45=~~
	\| cd45=		\| cd45=
	\| cd5=		\| cd5=
Line 111:		Line 113:
	\| cd57=		\| cd57=
	\| cd68=		\| cd68=
	\| cd7= ~~'''POSITIVE''' in glandular areas, rare staining in spindled areas~~		\| cd7=
	\| cd79a=		\| cd79a=
	\| cd8=		\| cd8=
Line 117:		Line 119:
	\| cdx2=		\| cdx2=
	\| cea=		\| cea=
	~~\| chromo=~~
	\| chromo=		\| chromo=
	\| ck17=		\| ck17=
Line 123:		Line 124:
	\| ck20= '''NEGATIVE'''		\| ck20= '''NEGATIVE'''
	\| ck34be12=		\| ck34be12=
	\| ck5_6= '''NEGATIVE'''		\| ck5_6= '''NEGATIVE'''
	\| ck7=		\| ck7= '''POSITIVE''' in glandular areas, rare staining in spindled areas
	\| cmv=		\| cmv=
	\| cmyc=		\| cmyc=
Line 139:		Line 140:
	\| fsh=		\| fsh=
	\| gastrin=		\| gastrin=
			\| gata3= '''NEGATIVE'''
	\| gcdfp=		\| gcdfp=
	\| gfap=		\| gfap=
Line 160:		Line 162:
	\| Idh-1=		\| Idh-1=
	\| inhibin=		\| inhibin=
			\| ini1=
	\| insulin=		\| insulin=
	\| kappa=		\| kappa=
Line 170:		Line 173:
	\| lh=		\| lh=
	\| lysozyme=		\| lysozyme=
	\| mammogl=		\| mammogl=
			\| map2=
	\| mcv=		\| mcv=
	\| melanin_a=		\| melanin_a=
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	\| myleoperox=		\| myleoperox=
	\| myo_d1=		\| myo_d1=
	~~\| myog=~~
	\| myog=		\| myog=
	\| nf=		\| nf=
			\| nkx3_1=
	\| nse=		\| nse=
	\| oct3_4=		\| oct3_4=
	\| p16=		\| p16=
			\| p501s=
	\| p53=		\| p53=
	\| p57=		\| p57=
	\| p63= '''NEGATIVE'''		\| p63= '''NEGATIVE'''
	\| panker=		\| panker=
	\| pax2=		\| pax2=
Line 195:		Line 200:
	\| pnl-2c=		\| pnl-2c=
	\| prolactin=		\| prolactin=
	\| psa= '''POSITIVE''' in glands, '''NEGATIVE''' in spindled areas		\| psa= '''POSITIVE''' in glands, '''NEGATIVE''' in spindled areas
	\| psap= '''POSITIVE''' in glands, weak blush in spindled areas		\| psap= '''POSITIVE''' in glands, weak blush in spindled areas
	\| rcc=		\| rcc=
	\| s100=		\| s100=
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	\| tdt=		\| tdt=
	\| tfe3=		\| tfe3=
			\| tfeb=
	\| thyrogl=		\| thyrogl=
	\| toxopl=		\| toxopl=
Line 211:		Line 217:
	\| uchl1=		\| uchl1=
	\| ulex_europe=		\| ulex_europe=
	\| vim=		\| vim= glands '''NEGATIVE''', spindle cells '''POSITIVE'''
	\| vip=		\| vip=
	\| vzv=		\| vzv=
	\| wt1=		\| wt1=
	}}		}}

	====Molecular testing====		====Molecular testing====
	=====Chromosomal translocations=====		=====Chromosomal translocations=====

Michael: Created page with "===Provided clinical history=== 72 year old man ===Site=== Prostate gland ===Primary image=== center|..."

2015-09-19T22:03:04Z

Created page with "===Provided clinical history=== 72 year old man ===Site=== Prostate gland ===Primary image=== 500px|link=|center|..."

New page

===Provided clinical history===
72 year old man

===Site===
Prostate gland

===Primary image===
[[Image: Sarcomatoid prostate carcinoma -- low mag.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Sarcomatoid prostate carcinoma -- intermed mag.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Sarcomatoid prostate carcinoma -- high mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[fibrosarcoma]], [[sarcomatoid urothelial carcinoma]], [[sarcomatoid prostate carcinoma]], metastatic [[sarcomatoid carcinoma]], [[pleomorphic undifferentiated sarcoma]]</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>Core biopsies 5 years ago had Gleason 6/10 in 2 cores, 5% of tissue, presented 1 month ago with gross hematuria, PSA 9.3 - up from 6.2 one year ago</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>Looks like a sarcomatoid changes... and funny looking glands. Not that hard.</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7= '''POSITIVE''' in glandular areas, rare staining in spindled areas
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| chromo=
| ck17=
| ck19=
| ck20= '''NEGATIVE'''
| ck34be12=
| ck5_6= '''NEGATIVE'''
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| myog=
| nf=
| nse=
| oct3_4=
| p16=
| p53=
| p57=
| p63= '''NEGATIVE'''
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa= '''POSITIVE''' in glands, '''NEGATIVE''' in spindled areas
| psap= '''POSITIVE''' in glands, weak blush in spindled areas
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}
====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>DIAGNOSIS GOES HERE</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]