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https://librepathology.org/w/index.php?action=history&feed=atom&title=Case_111
Case 111 - Revision history
2026-08-08T11:45:44Z
Revision history for this page on the wiki
MediaWiki 1.36.3
https://librepathology.org/w/index.php?title=Case_111&diff=40128&oldid=prev
Michael: /* Other cases */
2015-09-27T02:45:31Z
<p><span dir="auto"><span class="autocomment">Other cases</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:45, 27 September 2015</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases in <del style="font-weight: bold; text-decoration: none;">gynecological </del>pathology]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases in <ins style="font-weight: bold; text-decoration: none;">gynecologic </ins>pathology]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases in <del style="font-weight: bold; text-decoration: none;">gynecological </del>pathology - junior]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases in <ins style="font-weight: bold; text-decoration: none;">gynecologic </ins>pathology - junior]]</div></td></tr>
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Michael
https://librepathology.org/w/index.php?title=Case_111&diff=40127&oldid=prev
Michael at 02:43, 27 September 2015
2015-09-27T02:43:19Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:43, 27 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Provided clinical history===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Provided clinical history===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>28 year old woman with a positive pregnancy test. <del style="font-weight: bold; text-decoration: none;"> </del>Cornual mass on ultrasound. <del style="font-weight: bold; text-decoration: none;"> </del>No fetal heart identified.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>28 year old woman with a positive pregnancy test. Cornual mass on ultrasound. No fetal heart identified.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Site===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Site===</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{hidden|Intermediate magnification|[[Image: Ariasstella changes in endometrium 20x.jpg |500px|link=|center|]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{hidden|Intermediate magnification|[[Image: Ariasstella changes in endometrium 20x.jpg |500px|link=|center|]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><center>Intermediate magnification. [[H&E stain]].</center>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><center>Intermediate magnification. [[H&E stain]].</center>}}</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]</del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"><center>High magnification. [[H&E stain]].</center>}}</del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Differential diagnosis===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Differential diagnosis===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>{{hidden|Differential diagnosis|<center><del style="font-weight: bold; text-decoration: none;">CLEAR CELL CARCINOMA</del></center>}}</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>{{hidden|Differential diagnosis|<center><ins style="font-weight: bold; text-decoration: none;">[[clear cell carcinoma]]</ins></center>}}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Additional tests===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Additional tests===</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Diagnosis===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Diagnosis===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>{{hidden|Diagnosis|<center>ARIAS STELLA CHANGES/REACTION<del style="font-weight: bold; text-decoration: none;">. </del>The diagnosis in this case is straightforward and relatively easy in this very young patient with a positive pregnancy test. <del style="font-weight: bold; text-decoration: none;"> </del>However, it can be challenging in an older patient who comes in with bleeding. <del style="font-weight: bold; text-decoration: none;"> </del>Arias Stella reaction shows endometrial glands lined by clear cells with atypia. <del style="font-weight: bold; text-decoration: none;"> </del>Intranuclear inclusions (arrow) are often present. <del style="font-weight: bold; text-decoration: none;"> </del>There can be occasional mitotic activity, which can further heighten <del style="font-weight: bold; text-decoration: none;"> </del>its mimicry to clear cell carcinoma. Furthermore, the clear cells of Arias Stella are positive for Napsin and HNF1Beta, markers that are positive in clear cell carcinoma. AMACR is reportedly negative in Arias Stella while being positive in clear cell carcinoma although too few cases are tested to be confident of this claim. <del style="font-weight: bold; text-decoration: none;"> </center></del>}}</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>{{hidden|Diagnosis|<center>ARIAS STELLA CHANGES/REACTION<ins style="font-weight: bold; text-decoration: none;"></center></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><br></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>The diagnosis in this case is straightforward and relatively easy in this very young patient with a positive <ins style="font-weight: bold; text-decoration: none;">[[</ins>pregnancy<ins style="font-weight: bold; text-decoration: none;">]] </ins>test. However, it can be challenging in an older patient who comes in with bleeding. Arias Stella reaction shows endometrial glands lined by clear cells with atypia. Intranuclear inclusions (arrow) are often present. There can be occasional mitotic activity, which can further heighten its mimicry to <ins style="font-weight: bold; text-decoration: none;">[[</ins>clear cell carcinoma<ins style="font-weight: bold; text-decoration: none;">]]</ins>. Furthermore, the clear cells of Arias Stella are positive for Napsin and HNF1Beta, markers that are positive in clear cell carcinoma. <ins style="font-weight: bold; text-decoration: none;">[[</ins>AMACR<ins style="font-weight: bold; text-decoration: none;">]] </ins>is reportedly negative in Arias Stella while being positive in clear cell carcinoma although too few cases are tested to be confident of this claim.}}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Other cases===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Other cases===</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"><!-- SELECT A CATEGORY</del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases in gynecological pathology]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases in gynecological pathology]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>-<del style="font-weight: bold; text-decoration: none;">-></del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[Category:Cases in gynecological pathology </ins>- <ins style="font-weight: bold; text-decoration: none;">junior]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --></div></td></tr>
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</table>
Michael
Deprecated : Return type of RemexHtml\Tokenizer\PlainAttributes::offsetExists($key) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /var/www/w/vendor/wikimedia/remex-html/RemexHtml/Tokenizer/PlainAttributes.php on line 24 Deprecated : Return type of & RemexHtml\Tokenizer\PlainAttributes::offsetGet($key) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /var/www/w/vendor/wikimedia/remex-html/RemexHtml/Tokenizer/PlainAttributes.php on line 28 Deprecated : Return type of RemexHtml\Tokenizer\PlainAttributes::offsetSet($key, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /var/www/w/vendor/wikimedia/remex-html/RemexHtml/Tokenizer/PlainAttributes.php on line 32 Deprecated : Return type of RemexHtml\Tokenizer\PlainAttributes::offsetUnset($key) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /var/www/w/vendor/wikimedia/remex-html/RemexHtml/Tokenizer/PlainAttributes.php on line 39 Deprecated : Return type of RemexHtml\Tokenizer\PlainAttributes::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /var/www/w/vendor/wikimedia/remex-html/RemexHtml/Tokenizer/PlainAttributes.php on line 44
https://librepathology.org/w/index.php?title=Case_111&diff=40048&oldid=prev
Rudolf: Rudolf moved page Case111 to Case 111
2015-09-24T18:15:50Z
<p>Rudolf moved page <a href="/wiki/Case111" class="mw-redirect" title="Case111">Case111</a> to <a href="/wiki/Case_111" title="Case 111">Case 111</a></p>
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<td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:15, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-notice" lang="en"><div class="mw-diff-empty">(No difference)</div>
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Rudolf
https://librepathology.org/w/index.php?title=Case_111&diff=40042&oldid=prev
Vinita: Created page with "===Provided clinical history=== 28 year old woman with a positive pregnancy test. Cornual mass on ultrasound. No fetal heart identified. ===Site=== Pregnancy ===Primary im..."
2015-09-24T16:41:00Z
<p>Created page with "===Provided clinical history=== 28 year old woman with a positive pregnancy test. Cornual mass on ultrasound. No fetal heart identified. ===Site=== Pregnancy ===Primary im..."</p>
<p><b>New page</b></p><div>===Provided clinical history===<br />
28 year old woman with a positive pregnancy test. Cornual mass on ultrasound. No fetal heart identified.<br />
<br />
===Site===<br />
Pregnancy<br />
<br />
===Primary image===<br />
[[Image: Ariasstella changes in endometrium 4x.jpg |500px|link=|center|]]<br />
<center>Low magnification. [[H&E stain]].</center><br />
<br />
{{hidden|Intermediate magnification|[[Image: Ariasstella changes in endometrium 20x.jpg |500px|link=|center|]]<br />
<center>Intermediate magnification. [[H&E stain]].</center>}}<br />
<br />
{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]<br />
<center>High magnification. [[H&E stain]].</center>}}<br />
<br />
===Differential diagnosis===<br />
{{hidden|Differential diagnosis|<center>CLEAR CELL CARCINOMA</center>}}<br />
<br />
===Additional tests===<br />
====More history====<br />
{{hidden|More history|<center>MORE HISTORY HERE</center>}}<br />
<br />
====Ask a colleague====<br />
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}<br />
<br />
====Stains====<br />
{{Case Stains<br />
| blank=Dr Torres would ask why!<br />
| alcpas= <br />
| alc1= <br />
| alc25= <br />
| aur= <br />
| biel= <br />
| bili= <br />
| iron= <br />
| congored= <br />
| cresylv= <br />
| dieterle= <br />
| diffquik= <br />
| fontana= <br />
| gallyas= <br />
| giemsa= <br />
| gms= <br />
| gomori= <br />
| gram= <br />
| gremelius= <br />
| jms= <br />
| jones= <br />
| kinyoun= <br />
| luxol= <br />
| masson= <br />
| mmas= <br />
| movat= <br />
| mucicar= <br />
| oilredo= <br />
| orecein= <br />
| pas= <br />
| pasd= <br />
| pasf= <br />
| ptah= <br />
| prussian= <br />
| reticulin= <br />
| sudanblackb= <br />
| toluidine= <br />
| verhoeff= <br />
| vonkossa= <br />
| warthinstarry= <br />
| zn= <br />
}}<br />
====IHC====<br />
{{Case IHC<br />
| blank=Dr Torres would ask why!<br />
| a1at= <br />
| acth= <br />
| ae1ae3= <br />
| afp= <br />
| alk1= <br />
| amacr= <br />
| ar=<br />
| atrx= <br />
| b2microglobulin= <br />
| b72_3= <br />
| bcatenin= <br />
| bcl2= <br />
| bcl6= <br />
| bclxl= <br />
| c3= <br />
| ca9= <br />
| calcitonin= <br />
| calponin= <br />
| calretinin= <br />
| cam5p2= <br />
| cathepsink= <br />
| cd10= <br />
| cd117= <br />
| cd138= <br />
| cd15= <br />
| cd1a= <br />
| cd20= <br />
| cd21= <br />
| cd23= <br />
| cd3= <br />
| cd30= <br />
| cd31= <br />
| cd34= <br />
| cd35= <br />
| cd4= <br />
| cd43= <br />
| cd45= <br />
| cd5= <br />
| cd56= <br />
| cd57= <br />
| cd68= <br />
| cd7= <br />
| cd79a= <br />
| cd8= <br />
| cd99= <br />
| cdx2= <br />
| cea= <br />
| chromo= <br />
| ck17= <br />
| ck19= <br />
| ck20= <br />
| ck34be12= <br />
| ck5_6= <br />
| ck7= <br />
| cmv= <br />
| cmyc= <br />
| cyclin_d1= <br />
| d2_40= <br />
| desmin= <br />
| dog1= <br />
| ebv= <br />
| ema= <br />
| erpr= <br />
| f_viii= <br />
| f_xiiia= <br />
| fascin= <br />
| fh=<br />
| fsh= <br />
| gastrin= <br />
| gata3= <br />
| gcdfp= <br />
| gfap= <br />
| gh= <br />
| glucagon= <br />
| glypican3= <br />
| hbme1= <br />
| hbv_core= <br />
| hbv_surf= <br />
| hcaldesmon= <br />
| hcg= <br />
| helicobacter= <br />
| hepatocyte= <br />
| her2= <br />
| hhv8= <br />
| hmb45= <br />
| hnf1beta= POSITIVE<br />
| hpv= <br />
| hsv1= <br />
| hsv2= <br />
| Idh-1= <br />
| inhibin= <br />
| ini1= <br />
| insulin= <br />
| kappa= <br />
| ki67= <br />
| lambda= <br />
| leu7= <br />
| lga= <br />
| lgg= <br />
| lgm= <br />
| lh= <br />
| lysozyme= <br />
| mammogl=<br />
| map2= <br />
| mcv= <br />
| melanin_a= <br />
| mitf= <br />
| mum1= <br />
| myleoperox= <br />
| myo_d1= <br />
| myog= <br />
| nf= <br />
| nkx3_1= <br />
| nse= <br />
| oct3_4= <br />
| p16= <br />
| p501s= <br />
| p53= <br />
| p57= <br />
| p63= <br />
| panker= <br />
| pax2= <br />
| pax5= <br />
| pax8= <br />
| pcna= <br />
| pdgfr= <br />
| plap= <br />
| pnl-2c= <br />
| prolactin= <br />
| psa= <br />
| psap= <br />
| rcc= <br />
| s100= <br />
| sma= <br />
| somatsatin= <br />
| synapto= <br />
| tdt= <br />
| tfe3= <br />
| tfeb= <br />
| thyrogl= <br />
| toxopl= <br />
| tsh= <br />
| ttf1= <br />
| ubiquitin= <br />
| uchl1= <br />
| ulex_europe= <br />
| vim= <br />
| vip= <br />
| vzv= <br />
| wt1= <br />
}}<br />
<br />
====Molecular testing====<br />
=====Chromosomal translocations=====<br />
{{Case Translocations<br />
| blank=Dr Torres would ask why!<br />
| t1_13= <br />
| t2_13= <br />
| t8_14= <br />
| t9_22bcr_abl= <br />
| t9_22chn_ews= <br />
| t11_14= <br />
| t11_22dsrct= <br />
| t11_22ews= <br />
| t12_15= <br />
| t12_16afh= <br />
| t12_16liposar= <br />
| t12_22= <br />
| t14_18= <br />
| t15_17= <br />
| t16_21= <br />
| t17_22= <br />
| t21_22= <br />
| tx_1= <br />
| tx_17= <br />
| tx_18= <br />
}}<br />
=====Other molecular tests=====<br />
{{Case Molecular<br />
| blank=Dr Torres would ask why!<br />
| alk = <br />
| b_cell_clone = <br />
| bcl2 = <br />
| braf = <br />
| EBV_pcr = <br />
| egrf = <br />
| h3f3a = <br />
| hhv8_pcr = <br />
| identity_test = <br />
| idh1_2 = <br />
| jak2_v617f = <br />
| kit = <br />
| loh_1p19q = <br />
| t_cell_clone = <br />
}}<br />
<br />
===Diagnosis===<br />
{{hidden|Diagnosis|<center>ARIAS STELLA CHANGES/REACTION. The diagnosis in this case is straightforward and relatively easy in this very young patient with a positive pregnancy test. However, it can be challenging in an older patient who comes in with bleeding. Arias Stella reaction shows endometrial glands lined by clear cells with atypia. Intranuclear inclusions (arrow) are often present. There can be occasional mitotic activity, which can further heighten its mimicry to clear cell carcinoma. Furthermore, the clear cells of Arias Stella are positive for Napsin and HNF1Beta, markers that are positive in clear cell carcinoma. AMACR is reportedly negative in Arias Stella while being positive in clear cell carcinoma although too few cases are tested to be confident of this claim. </center>}}<br />
<br><br />
===Other cases===<br />
{{Cases navigation}}<br />
<br />
__NOTOC__<br />
<br />
[[Category:Cases]]<br />
<br />
<!-- SELECT A CATEGORY<br />
[[Category:Cases in gynecological pathology]]<br />
--><br />
<br />
[[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --></div>
Vinita