Jensflorian: HCG

2015-09-25T06:41:08Z

HCG

← Older revision		Revision as of 06:41, 25 September 2015
Line 152:		Line 152:
	\| hbv_surf=		\| hbv_surf=
	\| hcaldesmon=		\| hcaldesmon=
	\| hcg=		\| hcg= '''NEGATIVE'''
	\| helicobacter=		\| helicobacter=
	\| hepatocyte=		\| hepatocyte=

Jensflorian: created

2015-09-24T10:21:16Z

created

New page

===Provided clinical history===
16 year old female with signs of panhypopituitarism

===Site===
Floor of the IIIrd ventricle

===Primary image===
[[Image:Neuropathology_case_VIII_01.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image:Neuropathology_case_VIII_02.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|Very high magnification|[[Image: Neuropathology_case_VIII_03.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[Sarcoidosis]], [[Encephalitis]], [[Lymphoma]], [[Germinoma]], [[Melanoma]]</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>The tumor is located in the midline.</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>There are neoplastic cells among large reactive inflammatory lymphocytic infiltrates.</center>}}

====Stains====
{{Case Stains
| blank=Dr White would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram= '''NEGATIVE'''
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas= '''NEGATIVE'''
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr White would ask why!
| a1at=
| acth=
| ae1ae3= '''NEGATIVE'''
| afp= '''NEGATIVE'''
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2= '''NEGATIVE'''
| cathepsink=
| cd10=
| cd117= '''POSITIVE'''
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30= '''NEGATIVE'''
| cd31= '''NEGATIVE'''
| cd34= '''NEGATIVE'''
| cd35=
| cd4=
| cd43=
| cd45= '''Lymphocytes POSITIVE'''
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40= '''POSITIVE'''
| desmin=
| dog1=
| ebv=
| ema= '''NEGATIVE'''
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap= '''Few astrocytes positive'''
| gh=
| glucagon=
| glypican3= '''NEGATIVE'''
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67= [[Image: Neuropathology_case_VIII_04.jpg |500px|link=|center|]]
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a= '''NEGATIVE'''
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4= [[Image: Neuropathology_case_VIII_05.jpg |500px|link=|center|]]
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker= '''NEGATIVE'''
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap= '''POSITIVE'''
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma= '''NEGATIVE'''
| somatsatin=
| stat6=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr White would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr White would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[Germinoma]]</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]

[[Category:Cases in neuropathology]]
[[Category:Cases in neuropathology - senior]]

[[Category:Cases difficulty 3]]

Case 110 - Revision history

Jensflorian: HCG

Jensflorian: created