Calcium pyrophosphate deposition - Revision history

Michael: Redirected page to Chondrocalcinosis

2014-03-12T03:16:24Z

← Older revision		Revision as of 03:16, 12 March 2014
Line 1:		Line 1:
	~~'''Chondrocalcinosis''', also '''calcium pyrophosphate deposition''' and '''calcium pyrophosphate dihydrate deposition disease''' (abbreviated '''CPPD'''),<ref>URL:~~ [~~http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/]. Accessed on: 28 October 2011.</ref> is a benign condition of the~~ [~~[joints]].~~		#redirect [[Chondrocalcinosis]]

	It was previously known as '''pseudogout'''.<ref>URL: [http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp]. Accessed on: 12 March 2014.</ref>

	~~==General==~~
	*Classically found in the knee.
	*Associated with low bone mineral density and vascular calcification.<ref name=pmid23912799>{{Cite journal \| last1 = Abhishek \| first1 = A. \| last2 = Doherty \| first2 = S. \| last3 = Maciewicz \| first3 = R. \| last4 = Muir \| first4 = K. \| last5 = Zhang \| first5 = W. \| last6 = Doherty \| first6 = M. \| title = Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study. \| journal = Ann Rheum Dis \| volume = \| issue = \| pages = \| month = Aug \| year = 2013 \| doi = 10.1136/annrheumdis-2013-203400 \| PMID = 23912799 }}</ref>

	~~==Radiology==~~
	*Similar to [[osteoarthritis]] - joint space narrowing & subchondral sclerosis.<ref name=learningrads>URL: [http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm]. Accessed on: 9 October 2013.</ref>

	Findings suggestive of CPPD:<ref name=learningrads>URL: [http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm]. Accessed on: 9 October 2013.</ref>
	*Subchondral cysts (large) - important.
	*Intra-articular bodies, several.
	*Increased narrowing of patellofemoral joint.

	~~==Microscopic==~~
	~~Features:~~
	*Crystals with a rhomboid-shape.
	**Positively birefringent, blue when aligned.

	~~Notes:~~
	*Memory device: ''ABC+'' = ''a''ligned ''b''lue is ''c''alcium & ''c''uboid - positively birefringent.

	~~===Images===~~
	~~<gallery>~~
	~~Image:Pseudogout_-_intermed_mag.jpg \| Pseudogout - intermed. mag. (WC)~~
	~~Image:Pseudogout_-_high_mag.jpg \| Pseudogout - high mag. (WC)~~
	~~</gallery>~~
	~~www:~~
	*[http://ard.highwire.org/content/58/5/261/F2.large.jpg Pseudogout (highwire.org)].<ref name=pmid10225806>{{Cite journal \| last1 = Dieppe \| first1 = P. \| last2 = Swan \| first2 = A. \| title = Identification of crystals in synovial fluid. \| journal = Ann Rheum Dis \| volume = 58 \| issue = 5 \| pages = 261-3 \| month = May \| year = 1999 \| doi = \| PMID = 10225806 \| PMC = 1752883 \| URL = http://ard.highwire.org/content/58/5/261.full }}</ref>

	~~==Sign-out==~~
	~~<pre>~~
	~~KNEE - BONE AND SOFT TISSUE, RIGHT, KNEE ARTHROPLASTY:~~
	~~- DEGENERATIVE JOINT DISEASE WITH SYNOVIAL HYPERPLASIA AND~~
	~~NO SIGNIFICANT INFLAMMATION.~~
	~~- CRYSTALLINE DEPOSITS CONSISTENT WITH PSEUDOGOUT.~~
	~~- BONE WITH THIN TRABECULAE.~~
	~~</pre>~~
	~~<pre>~~
	~~BONE, LEFT KNEE, JOINT REPLACEMENT:~~
	~~- DEGENERATIVE JOINT DISEASE.~~
	~~- CRYSTALS CONSISTENT WITH PSEUDOGOUT.~~
	~~- SYNOVIAL HYPERPLASIA WITH RARE GIANT CELLS.~~
	~~- NEGATIVE FOR MALIGNANCY.~~
	~~</pre>~~
	~~===Micro===~~
	~~The soft tissue section shows readily apparent rhomboid-shaped crystalline deposits~~
	~~(compatible with pseudogout). The crystals polarize and have a light blue hue under~~
	~~polarized light. Synovial hyperplasia is present. No lymphoid aggregates are apparent.~~

	~~The bony section show thin bony trabeculae and cartilage with~~
	~~degenerative changes (surface fibrillation, thinning).~~

	~~==See also==~~
	*[[Joints]].
	*[[Crystals in body fluids]].

	~~==References==~~
	~~{{Reflist\|2}}~~

	~~[[Category:Crystals in body fluids~~]]

Michael at 03:14, 12 March 2014

2014-03-12T03:14:24Z

← Older revision		Revision as of 03:14, 12 March 2014
Line 1:		Line 1:
	'''~~Calcium~~ pyrophosphate deposition''', abbreviated '''CPPD''', is a benign condition of the [[joints]].		'''Chondrocalcinosis''', also '''calcium pyrophosphate deposition''' and '''calcium pyrophosphate dihydrate deposition disease''' (abbreviated '''CPPD'''),<ref>URL: [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/]. Accessed on: 28 October 2011.</ref> is a benign condition of the [[joints]].

	It was previously known as '''pseudogout'''.<ref>URL: [http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp]. Accessed on: 12 March 2014.</ref>		It was previously known as '''pseudogout'''.<ref>URL: [http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp]. Accessed on: 12 March 2014.</ref>

	It is also known as ''chondrocalcinosis'' and ''calcium pyrophosphate dihydrate deposition disease''.<ref>URL: [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/]. Accessed on: 28 October 2011.</ref>

	==General==		==General==

Michael: split out

2014-03-12T03:09:03Z

split out

New page

'''Calcium pyrophosphate deposition''', abbreviated '''CPPD''', is a benign condition of the [[joints]].

It was previously known as '''pseudogout'''.<ref>URL: [http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/pseudogout.asp]. Accessed on: 12 March 2014.</ref>

It is also known as ''chondrocalcinosis'' and ''calcium pyrophosphate dihydrate deposition disease''.<ref>URL: [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/]. Accessed on: 28 October 2011.</ref>

==General==
*Classically found in the knee.
*Associated with low bone mineral density and vascular calcification.<ref name=pmid23912799>{{Cite journal | last1 = Abhishek | first1 = A. | last2 = Doherty | first2 = S. | last3 = Maciewicz | first3 = R. | last4 = Muir | first4 = K. | last5 = Zhang | first5 = W. | last6 = Doherty | first6 = M. | title = Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study. | journal = Ann Rheum Dis | volume = | issue = | pages = | month = Aug | year = 2013 | doi = 10.1136/annrheumdis-2013-203400 | PMID = 23912799 }}</ref>

==Radiology==
*Similar to [[osteoarthritis]] - joint space narrowing & subchondral sclerosis.<ref name=learningrads>URL: [http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm]. Accessed on: 9 October 2013.</ref>

Findings suggestive of CPPD:<ref name=learningrads>URL: [http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm http://www.learningradiology.com/archives04/COW%20102-CPPD/cppdcorrectpage.htm]. Accessed on: 9 October 2013.</ref>
*Subchondral cysts (large) - important.
*Intra-articular bodies, several.
*Increased narrowing of patellofemoral joint.

==Microscopic==
Features:
*Crystals with a rhomboid-shape.
**Positively birefringent, blue when aligned.

Notes:
*Memory device: ''ABC+'' = ''a''ligned ''b''lue is ''c''alcium & ''c''uboid - positively birefringent.

===Images===
<gallery>
Image:Pseudogout_-_intermed_mag.jpg | Pseudogout - intermed. mag. (WC)
Image:Pseudogout_-_high_mag.jpg | Pseudogout - high mag. (WC)
</gallery>
www:
*[http://ard.highwire.org/content/58/5/261/F2.large.jpg Pseudogout (highwire.org)].<ref name=pmid10225806>{{Cite journal | last1 = Dieppe | first1 = P. | last2 = Swan | first2 = A. | title = Identification of crystals in synovial fluid. | journal = Ann Rheum Dis | volume = 58 | issue = 5 | pages = 261-3 | month = May | year = 1999 | doi = | PMID = 10225806 | PMC = 1752883 | URL = http://ard.highwire.org/content/58/5/261.full }}</ref>

==Sign-out==
<pre>
KNEE - BONE AND SOFT TISSUE, RIGHT, KNEE ARTHROPLASTY:
- DEGENERATIVE JOINT DISEASE WITH SYNOVIAL HYPERPLASIA AND
NO SIGNIFICANT INFLAMMATION.
- CRYSTALLINE DEPOSITS CONSISTENT WITH PSEUDOGOUT.
- BONE WITH THIN TRABECULAE.
</pre>
<pre>
BONE, LEFT KNEE, JOINT REPLACEMENT:
- DEGENERATIVE JOINT DISEASE.
- CRYSTALS CONSISTENT WITH PSEUDOGOUT.
- SYNOVIAL HYPERPLASIA WITH RARE GIANT CELLS.
- NEGATIVE FOR MALIGNANCY.
</pre>
===Micro===
The soft tissue section shows readily apparent rhomboid-shaped crystalline deposits
(compatible with pseudogout). The crystals polarize and have a light blue hue under
polarized light. Synovial hyperplasia is present. No lymphoid aggregates are apparent.

The bony section show thin bony trabeculae and cartilage with
degenerative changes (surface fibrillation, thinning).

==See also==
*[[Joints]].
*[[Crystals in body fluids]].

==References==
{{Reflist|2}}

[[Category:Crystals in body fluids]]