BRCA1 interacting protein C-terminal helicase 1 - Revision history

Michael at 16:11, 4 November 2024

2024-11-04T16:11:25Z

← Older revision		Revision as of 16:11, 4 November 2024
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	[[Image: Serous carcinoma - fallopian tube -- intermed mag.jpg \| thumb \| right \| ~~Serous~~ carcinoma of the fallopian tube. [[H&E stain]].]]		[[Image: Serous carcinoma - fallopian tube -- intermed mag.jpg \| thumb \| right \| Micrograph showing [[serous carcinoma of the fallopian tube]], a tumour that may be associated with a BRIP1 mutation. [[H&E stain]].]]
	'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP1''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.		'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP1''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.

Michael at 05:23, 4 November 2024

2024-11-04T05:23:30Z

← Older revision		Revision as of 05:23, 4 November 2024
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	[[Image: Serous carcinoma - fallopian tube -- intermed mag.jpg \| thumb \| right \| Serous carcinoma of the fallopian tube. [[H&E stain]].]]		[[Image: Serous carcinoma - fallopian tube -- intermed mag.jpg \| thumb \| right \| Serous carcinoma of the fallopian tube. [[H&E stain]].]]
	'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''~~BRIP~~''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.		'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP1''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.

	It is also known as ''BACH1'' and ''FANCJ''.		It is also known as ''BACH1'' and ''FANCJ''.

Michael at 05:22, 4 November 2024

2024-11-04T05:22:57Z

← Older revision		Revision as of 05:22, 4 November 2024
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			[[Image: Serous carcinoma - fallopian tube -- intermed mag.jpg \| thumb \| right \| Serous carcinoma of the fallopian tube. [[H&E stain]].]]
	'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.		'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.

Michael at 13:59, 8 September 2023

2023-09-08T13:59:26Z

← Older revision		Revision as of 13:59, 8 September 2023
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	'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP''', is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.		'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP''', is a tumour suppressor gene that interacts with [[BRCA1]] to help repair double-strand DNA breaks.<ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.

	It is also known as ''BACH1'' and ''FANCJ''.		It is also known as ''BACH1'' and ''FANCJ''.

Michael: rework

2023-09-08T13:58:01Z

rework

← Older revision		Revision as of 13:58, 8 September 2023
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	~~BRIP1 (~~BRCA1-interacting protein C-terminal helicase 1~~; AKA BACH1~~, ~~FANCJ)~~ is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.		'''BRCA1 interacting protein C-terminal helicase 1''', abbreviated '''BRIP''', is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990 https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref name=NBK1401>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/ https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.

			It is also known as ''BACH1'' and ''FANCJ''.

	==Disease associations==		==Disease associations==
	*Fanconi anemia ~~<ref>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref>~~		*Fanconi anemia with biallelic mutations (autosomal recessive manifestation).<ref name=NBK1401/>
	**with biallelic mutations (autosomal recessive manifestation)		*Breast and ovarian cancer with monoallelic mutation (autosomal dominant manifestation).<ref name=NBK1401/>
	*Breast and ovarian cancer<ref>~~URL:~~ [~~https://www.ncbi.nlm.nih.gov/books/NBK1401/~~]. ~~Accessed on~~: ~~05 March 2020.</ref>~~
	**With monoallelic mutation (autosomal dominant manifestation)		==See also==
			*[[Familial breast cancer]].

			==References==
			{{Reflist\|1}}

			[[Category:Gynecologic pathology]]
			[[Category:Molecular pathology]]

Michael: Michael moved page BRIP1 to BRCA1 interacting protein C-terminal helicase 1: title

2023-09-08T13:50:05Z

Michael moved page BRIP1 to BRCA1 interacting protein C-terminal helicase 1: title

← Older revision

Revision as of 13:50, 8 September 2023

Sarah A at 14:38, 5 March 2020

2020-03-05T14:38:54Z

← Older revision		Revision as of 14:38, 5 March 2020
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	BRIP1 (BRCA1-interacting protein C-terminal helicase 1) is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref>		BRIP1 (BRCA1-interacting protein C-terminal helicase 1; AKA BACH1, FANCJ) is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref> <ref>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref> It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.

			==Disease associations==
			*Fanconi anemia <ref>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref>
			**with biallelic mutations (autosomal recessive manifestation)
			*Breast and ovarian cancer<ref>URL: [https://www.ncbi.nlm.nih.gov/books/NBK1401/]. Accessed on: 05 March 2020.</ref>
			**With monoallelic mutation (autosomal dominant manifestation)

Sarah A: Created page with "BRIP1 (BRCA1-interacting protein C-terminal helicase 1) is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. URL: [https://www.n..."

2020-03-05T14:12:54Z

Created page with "BRIP1 (BRCA1-interacting protein C-terminal helicase 1) is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.n..."

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BRIP1 (BRCA1-interacting protein C-terminal helicase 1) is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. <ref>URL: [https://www.ncbi.nlm.nih.gov/gene/83990]. Accessed on: 05 March 2020.</ref>