Apocrine metaplasia of the breast - Revision history

Michael: /* Microscopic */

2016-05-09T21:36:36Z

Microscopic

← Older revision		Revision as of 21:36, 9 May 2016
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	**Prominent nuclear membrane.		**Prominent nuclear membrane.
	**Prominent, often single nucleolus.		**Prominent, often single nucleolus.
			*+/-Luminal papillary tufts.<ref>URL: [http://www.breastpathology.info/Benign%20proliferative%20disease.html http://www.breastpathology.info/Benign%20proliferative%20disease.html]. Accessed on: May 9, 2016.</ref>

	Note:		Note:

Michael: /* General */

2016-05-09T21:30:58Z

General

← Older revision		Revision as of 21:30, 9 May 2016
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	*Increased number of mitochondria.		*Increased number of mitochondria.
	**In other body sites this has different names, e.g. ''Hurthle cell change'' (thyroid), ''[[oncocytoma\|oncocytic]] change'' (kidney).		**In other body sites this has different names, e.g. ''Hurthle cell change'' (thyroid), ''[[oncocytoma\|oncocytic]] change'' (kidney).

			==Gross==
			*Blue dome cysts.<ref name=pmid25610180>{{Cite journal \| last1 = Rodrigues \| first1 = G. \| last2 = Prabhu \| first2 = R. \| last3 = Nair \| first3 = R. \| last4 = Thinda \| first4 = R. \| title = A blue-domed cyst of bloodgood. \| journal = Eurasian J Med \| volume = 43 \| issue = 2 \| pages = 132 \| month = Aug \| year = 2011 \| doi = 10.5152/eajm.2011.30 \| PMID = 25610180 }}</ref>

	==Microscopic==		==Microscopic==

Michael: /* Images */

2016-04-02T16:44:00Z

Images

← Older revision		Revision as of 16:44, 2 April 2016
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	===Images===		===Images===
			====Case====
			<gallery>
			Image: Apocrine metaplasia -- low mag.jpg \| AM - low mag.
			Image: Apocrine metaplasia -- intermed mag.jpg \| AM - intermed. mag.
			Image: Apocrine metaplasia -- high mag.jpg \| AM - high mag.
			Image: Apocrine metaplasia -- very high mag.jpg \| AM - very high mag.
			Image: Apocrine metaplasia - alt -- very high mag.jpg \| AM - very high mag.
			</gallery>
			====Others====
	<gallery>		<gallery>
	Image:Fibrocystic_change_-_very_high_mag.jpg \| FCC with apocrine metaplasia (right bottom of image) - high mag. (WC/Nephron).		Image:Fibrocystic_change_-_very_high_mag.jpg \| FCC with apocrine metaplasia (right bottom of image) - high mag. (WC/Nephron).

Michael: /* General */

2016-03-10T18:35:27Z

General

← Older revision		Revision as of 18:35, 10 March 2016
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	===Etiology===		===Etiology===
	*Increased number of mitochondria.		*Increased number of mitochondria.
	**In other body sites this has different names, e.g. ''[[Hurthle cell change]]'' (thyroid), ''[[oncocytoma\|oncocytic]] change'' (kidney ~~- [[oncocytoma]], thyroid~~).		**In other body sites this has different names, e.g. ''Hurthle cell change'' (thyroid), ''[[oncocytoma\|oncocytic]] change'' (kidney).

	==Microscopic==		==Microscopic==

Michael at 18:33, 10 March 2016

2016-03-10T18:33:27Z

← Older revision		Revision as of 18:33, 10 March 2016
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	'''Apocrine metaplasia of the breast''', also '''apocrine metaplasia''', is a benign change in the breast without increased risk of malignancy.		'''Apocrine metaplasia of the breast''', also '''apocrine metaplasia''', is a benign change in the [[breast]] without increased risk of malignancy.

	==General==		==General==

Michael: /* General */

2016-03-10T18:32:47Z

General

← Older revision		Revision as of 18:32, 10 March 2016
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	==General==		==General==
	*Benign/not significant. Can be considered to be pretty wallpaper in the house of breast pathology.		*Benign/not significant. Can be considered to be pretty wallpaper in the house of breast pathology.
			*Very common in adults.
			*''Apocrine lesions'' as a group are usually benign, some pre-neoplastic and some malignant.<ref name=pmid18042688>{{Cite journal \| last1 = Wells \| first1 = CA. \| last2 = El-Ayat \| first2 = GA. \| title = Non-operative breast pathology: apocrine lesions. \| journal = J Clin Pathol \| volume = 60 \| issue = 12 \| pages = 1313-20 \| month = Dec \| year = 2007 \| doi = 10.1136/jcp.2006.040626 \| PMID = 18042688 }}</ref>

	===Etiology===		===Etiology===

Michael: Created page with "'''Apocrine metaplasia of the breast''', also '''apocrine metaplasia''', is a benign change in the breast without increased risk of malignancy. ==General== *Benign/not signif..."

2016-03-10T18:28:18Z

Created page with "'''Apocrine metaplasia of the breast''', also '''apocrine metaplasia''', is a benign change in the breast without increased risk of malignancy. ==General== *Benign/not signif..."

New page

'''Apocrine metaplasia of the breast''', also '''apocrine metaplasia''', is a benign change in the breast without increased risk of malignancy.

==General==
*Benign/not significant. Can be considered to be pretty wallpaper in the house of breast pathology.

===Etiology===
*Increased number of mitochondria.
**In other body sites this has different names, e.g. ''[[Hurthle cell change]]'' (thyroid), ''[[oncocytoma|oncocytic]] change'' (kidney - [[oncocytoma]], thyroid).

==Microscopic==
Features:
*Eosinophilic cytoplasm - '''key feature'''.
*Voluminous pink cytoplasm.
*Apocrine snouts may be present.
**Small protrusiona at the apical aspect of the cell (composed of cytoplasm and plasma membrane).
*Central round nucleus
**Prominent nuclear membrane.
**Prominent, often single nucleolus.

Note:
*Apocrine changes, i.e. cytoplasmic eosinophilia, can appear in malignant tumours; eosinophilia doesn't make something benign.

===Images===
<gallery>
Image:Fibrocystic_change_-_very_high_mag.jpg | FCC with apocrine metaplasia (right bottom of image) - high mag. (WC/Nephron).
Image:Breast ApocrineChange HP CTR.jpg|Breast - Apocrine Change - high power (SKB)
</gallery>

==Sign out==
*Typically not reported.

==See also==
*[[Oncocytoma]].

==References==
{{Reflist|1}}

[[Category:Breast pathology]]