Aortic valve grossing - Revision history

Michael at 04:32, 4 September 2014

2014-09-04T04:32:42Z

← Older revision		Revision as of 04:32, 4 September 2014
Line 9:		Line 9:
	*Thinning is suggestive of [[myxomatous degeneration]]. Myxomatous degeneration is something that is seen in connective tissue disorders, e.g. [[Marfan syndrome]]; it tends to be in younger people.		*Thinning is suggestive of [[myxomatous degeneration]]. Myxomatous degeneration is something that is seen in connective tissue disorders, e.g. [[Marfan syndrome]]; it tends to be in younger people.
	*[[Bicuspid aortic valve]] = leftlets fused ''and'' no raphe (uncommon) ''or'' raphe does not reach the free margin of the cusp.<ref name=Ref_AoGP2>{{Ref AoGP\|2}}</ref>		*[[Bicuspid aortic valve]] = leftlets fused ''and'' no raphe (uncommon) ''or'' raphe does not reach the free margin of the cusp.<ref name=Ref_AoGP2>{{Ref AoGP\|2}}</ref>

	==Protocol==		==Protocol==
	*Specimen: aortic valve tissue.		*Specimen: aortic valve tissue.
Line 25:		Line 24:

	===Alternate approaches===		===Alternate approaches===
			*None.

	==Pathology==		==Pathology==
Line 38:		Line 38:

	===Related protocols===		===Related protocols===
	*[[Mitral valve]].		*[[Mitral valve grossing]].

	==References==		==References==

Michael at 04:31, 4 September 2014

2014-09-04T04:31:52Z

← Older revision		Revision as of 04:31, 4 September 2014
Line 8:		Line 8:
	*Vegetations are usually along the free edge.		*Vegetations are usually along the free edge.
	*Thinning is suggestive of [[myxomatous degeneration]]. Myxomatous degeneration is something that is seen in connective tissue disorders, e.g. [[Marfan syndrome]]; it tends to be in younger people.		*Thinning is suggestive of [[myxomatous degeneration]]. Myxomatous degeneration is something that is seen in connective tissue disorders, e.g. [[Marfan syndrome]]; it tends to be in younger people.
	*[[Bicuspid aortic valve]] = leftlets fused ''and'' no raphe (uncommon) ''or'' raphe does not reach the free margin of the cusp.<ref>~~Rose, Alan G. (2008). Atlas of Gross Pathology with Histologic Correlation (1st ed.). Cambridge University Press. p.~~ 2~~. ISBN 978-0521868792.~~</ref>		*[[Bicuspid aortic valve]] = leftlets fused ''and'' no raphe (uncommon) ''or'' raphe does not reach the free margin of the cusp.<ref name=Ref_AoGP2>{{Ref AoGP\|2}}</ref>

	==Protocol==		==Protocol==

Michael: create

2014-09-04T04:29:32Z

create

New page

This article covers '''aortic valve grossing'''. The [[aortic valve]] usually comes to pathology because of [[calcific aortic stenosis]]; however, there are a few less common reasons it may come.

[[Mitral valve grossing]] is dealt with in a separate protocol.

==Introduction==
*The vast majority of valves are [[calcific aortic stenosis]] and can be proven by the "drop test"; if you drop a calcified valve on a metal surface it goes "clank". Most patients are in their 70s.
**If a patient is younger (50s or younger) one should look carefully for fusion, i.e. bucuspid valve.
*Vegetations are usually along the free edge.
*Thinning is suggestive of [[myxomatous degeneration]]. Myxomatous degeneration is something that is seen in connective tissue disorders, e.g. [[Marfan syndrome]]; it tends to be in younger people.
*[[Bicuspid aortic valve]] = leftlets fused ''and'' no raphe (uncommon) ''or'' raphe does not reach the free margin of the cusp.<ref>Rose, Alan G. (2008). Atlas of Gross Pathology with Histologic Correlation (1st ed.). Cambridge University Press. p. 2. ISBN 978-0521868792.</ref>

==Protocol==
*Specimen: aortic valve tissue.
*Number of cusps: [ number ].
*Measurements (base-to-free edge x along the free edge x thickness): H x L x T, H x L x T and H x L x T cm.
*Calcification: [ absent / suspicious / present ], [minimal / moderate / marked].
*Vegetations: [ none / suspicious / present ].
*Thinning: [ absent / suspicious / present ].
*Additional findings: [ none / fenestrations ].
*Representative sections are submitted from each cusp in block A1.

===Protocol notes===
*May be a gross only diagnosis.
*Sections are cut perpendicular to the free edge.

===Alternate approaches===

==Pathology==
<gallery>
Image:Aortic_stenosis_rheumatic,_gross_pathology_20G0014_lores.jpg | Calcific aortic stenosis (WC)
</gallery>

Additional images:
*[http://circ.ahajournals.org/content/106/8/900.full.pdf Bicuspid valve (ahajournals.org)].<ref name=pmid12186790>{{Cite journal | last1 = Fedak | first1 = PW. | last2 = Verma | first2 = S. | last3 = David | first3 = TE. | last4 = Leask | first4 = RL. | last5 = Weisel | first5 = RD. | last6 = Butany | first6 = J. | title = Clinical and pathophysiological implications of a bicuspid aortic valve. | journal = Circulation | volume = 106 | issue = 8 | pages = 900-4 | month = Aug | year = 2002 | doi = | PMID = 12186790 }}</ref>
==See also==
*[[Heart valves]].
*[[Cardiovascular pathology]].

===Related protocols===
*[[Mitral valve]].

==References==
{{Reflist|2}}

[[Category:Gross pathology]]
[[Category:Cardiovascular pathology]]