Aggressive angiomyxoma - Revision history

Michael at 00:12, 17 February 2014

2014-02-17T00:12:07Z

← Older revision		Revision as of 00:12, 17 February 2014
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	\| Prognosis = benign, locally aggressive		\| Prognosis = benign, locally aggressive
	\| Other =		\| Other =
	\| ClinDDx = [[Bartholin cyst]]		\| ClinDDx = [[Bartholin cyst]], [[angiomyofibroblastoma]]
	\| Tx = excision		\| Tx = excision
	}}		}}

Michael: /* Microscopic */

2014-02-16T23:45:30Z

Microscopic

← Older revision		Revision as of 23:45, 16 February 2014
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	<gallery>		<gallery>
	Image:Aggressive_angiomyxoma_-_intermed_mag.jpg \| Aggressive angiomyxoma - intermed. mag. (WC/Nephron)		Image:Aggressive_angiomyxoma_-_intermed_mag.jpg \| Aggressive angiomyxoma - intermed. mag. (WC/Nephron)
			Image:Aggressive_angiomyxoma_-_high_mag.jpg \| Aggressive angiomyxoma - high mag. (WC/Nephron)
	Image:Aggressive_angiomyxoma_-_very_high_mag.jpg \| Aggressive angiomyxoma - very high mag. (WC/Nephron)		Image:Aggressive_angiomyxoma_-_very_high_mag.jpg \| Aggressive angiomyxoma - very high mag. (WC/Nephron)
	</gallery>		</gallery>

Michael: +infobox

2014-02-16T23:44:40Z

+infobox

← Older revision		Revision as of 23:44, 16 February 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Aggressive_angiomyxoma_-_very_high_mag.jpg
			\| Width =
			\| Caption = Aggressive angiomyxoma. [[H&E stain]].
			\| Synonyms =
			\| Micro = thick blood vessels that meld into the surrounding stroma, [[myxoid stroma]], small stellate cells/spindle cells without significant nuclear atypia
			\| Subtypes =
			\| LMDDx = [[angiomyofibroblastoma]], [[neurofibroma]], [[myxoma]]
			\| Stains =
			\| IHC = desmin +ve, vimentin +ve, ER +ve, PR +ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = poorly circumscribed lesion with a "rubbery" or "gelatinous" consistency
			\| Grossing =
			\| Site = [[soft tissue lesions\|soft tissue]] - typically [[vulva]], [[scrotum]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = mass lesion
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign, locally aggressive
			\| Other =
			\| ClinDDx = [[Bartholin cyst]]
			\| Tx = excision
			}}
	'''Aggressive angiomyxoma''', also '''deep aggressive angiomyxoma''', is a rare benign lesion, typically of the [[vulva]], with a locally aggressive behaviour.		'''Aggressive angiomyxoma''', also '''deep aggressive angiomyxoma''', is a rare benign lesion, typically of the [[vulva]], with a locally aggressive behaviour.

Michael: split out

2014-02-16T23:38:51Z

split out

← Older revision		Revision as of 23:38, 16 February 2014
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	#~~redirect~~ [[~~Soft_tissue_lesions~~#~~Aggressive_angiomyxoma~~]]		'''Aggressive angiomyxoma''', also '''deep aggressive angiomyxoma''', is a rare benign lesion, typically of the [[vulva]], with a locally aggressive behaviour.

			==General==
			*Classically a [[vulva]]r mass or (less commonly) a [[scrotum\|scrotal]] mass.
			**Case report of a thigh lesion.<ref name=pmid18338163>{{Cite journal \| last1 = Heffernan \| first1 = EJ. \| last2 = Hayes \| first2 = MM. \| last3 = Alkubaidan \| first3 = FO. \| last4 = Clarkson \| first4 = PW. \| last5 = Munk \| first5 = PL. \| title = Aggressive angiomyxoma of the thigh. \| journal = Skeletal Radiol \| volume = 37 \| issue = 7 \| pages = 673-8 \| month = Jul \| year = 2008 \| doi = 10.1007/s00256-008-0465-0 \| PMID = 18338163 }}</ref>
			*Benign - no metastatic potential.
			*"Aggressive" as it has a high recurrance.

			==Gross==
			*Poorly circumscribed.
			*"Rubbery" or "gelatinous".

			Location:
			*[[Vulva]] - classic location.

			Clinical DDx:
			*[[Bartholin cyst]].

			==Microscopic==
			Features:<ref name=Ref_WMSP624>{{Ref WMSP\|624}}</ref>
			#Thick blood vessels that meld into the surrounding stroma - '''key feature'''.
			#[[Myxoid stroma]] - '''key feature'''.
			#Small stellate cell/spindle cells without significant nuclear atypia.

			DDx:
			*[[Angiomyofibroblastoma]].<ref name=pmid1314521>{{Cite journal \| last1 = Fletcher \| first1 = CD. \| last2 = Tsang \| first2 = WY. \| last3 = Fisher \| first3 = C. \| last4 = Lee \| first4 = KC. \| last5 = Chan \| first5 = JK. \| title = Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. \| journal = Am J Surg Pathol \| volume = 16 \| issue = 4 \| pages = 373-82 \| month = Apr \| year = 1992 \| doi = \| PMID = 1314521 }}</ref>
			*[[Neurofibroma]].
			*[[Myxoma]].

			===Images===
			<gallery>
			Image:Aggressive_angiomyxoma_-_intermed_mag.jpg \| Aggressive angiomyxoma - intermed. mag. (WC/Nephron)
			Image:Aggressive_angiomyxoma_-_very_high_mag.jpg \| Aggressive angiomyxoma - very high mag. (WC/Nephron)
			</gallery>
			www:
			*[http://www.webpathology.com/image.asp?n=1&Case=99 Aggressive angiomyxoma - low mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?case=99&n=2 Aggressive angiomyxoma - high mag. (webpathology.com)].
			*[http://path.upmc.edu/cases/case538.html Aggressive angiomyxoma - several images (upmc.edu)].

			==IHC==
			Features:<ref name=Ref_WMSP624>{{Ref WMSP\|624}}</ref>
			*Desmin +ve.
			*Vimentin +ve.
			*ER +ve.
			*PR +ve.

			==See also==
			[[Soft tissue lesions]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Soft tissue lesions]]

Michael: +cat.

2011-10-20T05:09:16Z

+cat.

← Older revision		Revision as of 05:09, 20 October 2011
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	#redirect [[Soft_tissue_lesions#Aggressive_angiomyxoma]]		#redirect [[Soft_tissue_lesions#Aggressive_angiomyxoma]]

			[[Category:Diagnosis]]

Michael: redirect

2011-08-17T03:55:25Z

redirect

New page

#redirect [[Soft_tissue_lesions#Aggressive_angiomyxoma]]