Adenoid cystic carcinoma - Revision history

Michael at 15:42, 20 December 2023

2023-12-20T15:42:56Z

← Older revision		Revision as of 15:42, 20 December 2023
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	==Sign out==		==Sign out==
	===Micro===		===Micro===
	The sections show a tumour with cribriform architecture. The cystic spaces have basophilic material. The tumour cells are carrot-like and have scant/modest cytoplasm.		The sections show a tumour with a cribriform architecture. The cystic spaces have basophilic material. The tumour cells are carrot-like and have scant/modest cytoplasm.

	==See also==		==See also==

Michael: create

2023-12-20T15:41:24Z

create

← Older revision		Revision as of 15:41, 20 December 2023
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	**Seen in ~50% of cases.		**Seen in ~50% of cases.
	**Worse prognosis if present, esp. if fusion assoc. with transcription.		**Worse prognosis if present, esp. if fusion assoc. with transcription.

			==Sign out==
			===Micro===
			The sections show a tumour with cribriform architecture. The cystic spaces have basophilic material. The tumour cells are carrot-like and have scant/modest cytoplasm.

	==See also==		==See also==

Michael: /* Microscopic */

2018-05-09T17:07:44Z

Microscopic

← Older revision		Revision as of 17:07, 9 May 2018
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	*[[Pleomorphic adenoma]], esp. if encapsulated.		*[[Pleomorphic adenoma]], esp. if encapsulated.
	*[[Epithelial-myoepithelial carcinoma]] - esp. for AdCC tubular variant.		*[[Epithelial-myoepithelial carcinoma]] - esp. for AdCC tubular variant.
	*[[Human papillomavirus-related carcinoma with adenoid cystic-like features]].		*[[Human papillomavirus-related multiphenotypic sinonasal carcinoma]] (previously known as [[human papillomavirus-related carcinoma with adenoid cystic-like features]]).
	*[[Intraductal carcinoma of the salivary gland]].		*[[Intraductal carcinoma of the salivary gland]].

Michael at 17:06, 9 May 2018

2018-05-09T17:06:58Z

← Older revision		Revision as of 17:06, 9 May 2018
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	\| Micro = [[cribriform architecture]] (other patterns: solid, cords, (bilayered) tubules), cystic spaces filled with basophilic material, scant cytoplasm in most cells, nucleus - small, hyaline stroma		\| Micro = [[cribriform architecture]] (other patterns: solid, cords, (bilayered) tubules), cystic spaces filled with basophilic material, scant cytoplasm in most cells, nucleus - small, hyaline stroma
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[pleomorphic adenoma]], [[epithelial-myoepithelial carcinoma]]		\| LMDDx = [[pleomorphic adenoma]], [[epithelial-myoepithelial carcinoma]], [[intraductal carcinoma of the salivary gland\|intraductal carcinoma]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	*[[Epithelial-myoepithelial carcinoma]] - esp. for AdCC tubular variant.		*[[Epithelial-myoepithelial carcinoma]] - esp. for AdCC tubular variant.
	*[[Human papillomavirus-related carcinoma with adenoid cystic-like features]].		*[[Human papillomavirus-related carcinoma with adenoid cystic-like features]].
			*[[Intraductal carcinoma of the salivary gland]].

	===Images===		===Images===

Brigitte: /* www */

2018-04-26T13:37:07Z

www

← Older revision		Revision as of 13:37, 26 April 2018
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	Image: Adenoid cystic carcinoma of the trachea - alt -- very high mag.jpg \| AdCC trachea - very high mag.		Image: Adenoid cystic carcinoma of the trachea - alt -- very high mag.jpg \| AdCC trachea - very high mag.
	</gallery>		</gallery>
	~~====www====~~
	*[http://www.nature.com/modpathol/journal/v16/n12/fig_tab/3880915f2.html Adenoid cystic carcinoma (nature.com)].

	===Grading===		===Grading===
	Based on solid component:		Based on solid component:

Michael: /* Microscopic */ +ddx more

2017-09-06T15:42:33Z

Microscopic: +ddx more

← Older revision		Revision as of 15:42, 6 September 2017
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	*[[Pleomorphic adenoma]], esp. if encapsulated.		*[[Pleomorphic adenoma]], esp. if encapsulated.
	*[[Epithelial-myoepithelial carcinoma]] - esp. for AdCC tubular variant.		*[[Epithelial-myoepithelial carcinoma]] - esp. for AdCC tubular variant.
			*[[Human papillomavirus-related carcinoma with adenoid cystic-like features]].

	===Images===		===Images===

Michael at 04:26, 17 January 2017

2017-01-17T04:26:40Z

← Older revision		Revision as of 04:26, 17 January 2017
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	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing =
	\| Site = [[salivary gland]], [[breast]], [[lung]], [[skin]], others		\| Site = [[salivary gland]], [[breast]], [[lung]], [[skin]], [[trachea]], others
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =

Michael: /* Images */

2017-01-17T04:26:20Z

Images

← Older revision		Revision as of 04:26, 17 January 2017
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	===Images===		===Images===
	<gallery>		<gallery>

	Image:Adenoid cystic carcinoma - low mag.jpg \| AdCC - low mag. (WC/Nephron)		Image:Adenoid cystic carcinoma - low mag.jpg \| AdCC - low mag. (WC/Nephron)
	Image:Adenoid_cystic_carcinoma_-_intermed_mag.jpg \| AdCC - intermed. mag. (WC/Nephron)		Image:Adenoid_cystic_carcinoma_-_intermed_mag.jpg \| AdCC - intermed. mag. (WC/Nephron)
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	Image:Adenoid cystic carcinoma - very high mag.jpg \| AdCC - very high mag. (WC/Nephron)		Image:Adenoid cystic carcinoma - very high mag.jpg \| AdCC - very high mag. (WC/Nephron)
	Image:Adenoid_cystic_carcinoma_-a-_very_high_mag.jpg \| AdCC - very high mag. (WC/Nephron)		Image:Adenoid_cystic_carcinoma_-a-_very_high_mag.jpg \| AdCC - very high mag. (WC/Nephron)
	File:Breast_AdenoidCysticCarcinoma_SolidType_14BR***.jpg \| AdCC - solid type (WC/~~sarahkayb~~)		File:Breast_AdenoidCysticCarcinoma_SolidType_14BR***.jpg \| AdCC of breast - solid type (WC/Sarahkayb)
	</gallery>		</gallery>
	www:		<gallery>
			Image: Adenoid cystic carcinoma of the trachea -- low mag.jpg \| AdCC [[trachea]] - low mag.
			Image: Adenoid cystic carcinoma of the trachea -- intermed mag.jpg \| AdCC trachea - intermed. mag.
			Image: Adenoid cystic carcinoma of the trachea -- high mag.jpg \| AdCC trachea - high mag.
			Image: Adenoid cystic carcinoma of the trachea -- very high mag.jpg \| AdCC trachea - very high mag.
			Image: Adenoid cystic carcinoma of the trachea - alt -- very high mag.jpg \| AdCC trachea - very high mag.
			</gallery>
			====www====
	*[http://www.nature.com/modpathol/journal/v16/n12/fig_tab/3880915f2.html Adenoid cystic carcinoma (nature.com)].		*[http://www.nature.com/modpathol/journal/v16/n12/fig_tab/3880915f2.html Adenoid cystic carcinoma (nature.com)].

Jensflorian: /* Images */ solid type added

2016-10-19T06:36:06Z

Images: solid type added

← Older revision		Revision as of 06:36, 19 October 2016
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	Image:Adenoid cystic carcinoma - very high mag.jpg \| AdCC - very high mag. (WC/Nephron)		Image:Adenoid cystic carcinoma - very high mag.jpg \| AdCC - very high mag. (WC/Nephron)
	Image:Adenoid_cystic_carcinoma_-a-_very_high_mag.jpg \| AdCC - very high mag. (WC/Nephron)		Image:Adenoid_cystic_carcinoma_-a-_very_high_mag.jpg \| AdCC - very high mag. (WC/Nephron)
			File:Breast_AdenoidCysticCarcinoma_SolidType_14BR***.jpg \| AdCC - solid type (WC/sarahkayb)
	</gallery>		</gallery>
	www:		www:

Michael: /* IHC */

2016-08-01T22:12:43Z

IHC

← Older revision		Revision as of 22:12, 1 August 2016
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	==IHC==		==IHC==
	Features:<ref name=pmid19360297>{{Cite journal \| last1 = Sequeiros-Santiago \| first1 = G. \| last2 = García-Carracedo \| first2 = D. \| last3 = Fresno \| first3 = MF. \| last4 = Suarez \| first4 = C. \| last5 = Rodrigo \| first5 = JP. \| last6 = Gonzalez \| first6 = MV. \| title = Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands. \| journal = Oncol Rep \| volume = 21 \| issue = 5 \| pages = 1215-22 \| month = May \| year = 2009 \| doi = \| PMID = 19360297 }}</ref>		Features:<ref name=pmid19360297>{{Cite journal \| last1 = Sequeiros-Santiago \| first1 = G. \| last2 = García-Carracedo \| first2 = D. \| last3 = Fresno \| first3 = MF. \| last4 = Suarez \| first4 = C. \| last5 = Rodrigo \| first5 = JP. \| last6 = Gonzalez \| first6 = MV. \| title = Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands. \| journal = Oncol Rep \| volume = 21 \| issue = 5 \| pages = 1215-22 \| month = May \| year = 2009 \| doi = \| PMID = 19360297 }}</ref>
	*CD117 +ve.		*[[CD117]] +ve.
	*Cyclin D1 +ve/-ve.		*Cyclin D1 +ve/-ve.

	Others:<ref name=pmid24037641>{{Cite journal \| last1 = Thompson \| first1 = LD. \| last2 = Penner \| first2 = C. \| last3 = Ho \| first3 = NJ. \| last4 = Foss \| first4 = RD. \| last5 = Miettinen \| first5 = M. \| last6 = Wieneke \| first6 = JA. \| last7 = Moskaluk \| first7 = CA. \| last8 = Stelow \| first8 = EB. \| title = Sinonasal Tract and Nasopharyngeal Adenoid Cystic Carcinoma: A Clinicopathologic and Immunophenotypic Study of 86 Cases. \| journal = Head Neck Pathol \| volume = \| issue = \| pages = \| month = Sep \| year = 2013 \| doi = 10.1007/s12105-013-0487-3 \| PMID = 24037641 }}</ref>		Others:<ref name=pmid24037641>{{Cite journal \| last1 = Thompson \| first1 = LD. \| last2 = Penner \| first2 = C. \| last3 = Ho \| first3 = NJ. \| last4 = Foss \| first4 = RD. \| last5 = Miettinen \| first5 = M. \| last6 = Wieneke \| first6 = JA. \| last7 = Moskaluk \| first7 = CA. \| last8 = Stelow \| first8 = EB. \| title = Sinonasal Tract and Nasopharyngeal Adenoid Cystic Carcinoma: A Clinicopathologic and Immunophenotypic Study of 86 Cases. \| journal = Head Neck Pathol \| volume = \| issue = \| pages = \| month = Sep \| year = 2013 \| doi = 10.1007/s12105-013-0487-3 \| PMID = 24037641 }}</ref>
	*CK7 +ve.		*[[CK7]] +ve.
	*Pankeratin +ve.		*[[Pankeratin]] +ve.
	*p63 +ve.		*[[p63]] +ve.
	*Calponin +ve.		*Calponin +ve.
	*S-100 +ve.		*S-100 +ve.