Acute duodenitis - Revision history

Michael: +images, +infobox

2014-04-30T00:32:31Z

+images, +infobox

← Older revision		Revision as of 00:32, 30 April 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Acute duodenitis -- intermed mag.jpg
			\| Width =
			\| Caption = Acute duodenitis. [[H&E stain]].
			\| Synonyms =
			\| Micro = [[neutrophil]]s - "found without searching", [[eosinophil]]s - "found without searching", plasma cells (increased), intraepithelial lymphocytes
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[duodenum]]
			\| Assdx = [[Helicobacter gastritis]]
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy = erythema
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx = dependent on underlying cause
			}}
	'''Acute duodenitis''', abbreviated '''AD''', is an acute inflammatory process of the [[duodenum]]. It is relatively uncommon.		'''Acute duodenitis''', abbreviated '''AD''', is an acute inflammatory process of the [[duodenum]]. It is relatively uncommon.

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	Features:		Features:
	*Intraepithelial lymphocytes.		*Intraepithelial lymphocytes.
	*~~Neutrophils~~ - "found without searching" - '''key feature'''.		*[[Neutrophil]]s - "found without searching" - '''key feature'''.
	*~~Eosinophils~~ - "found without searching" - '''key feature'''.		*[[Eosinophil]]s - "found without searching" - '''key feature'''.
	*Plasma ~~cells~~ (increased).		*[[Plasma cell]]s (increased).

	Notes:		Notes:
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	**[[NSAID]]s not commonly assoc. with acute inflammation;<ref name=pmid8406146>{{cite journal \|author=Taha AS, Dahill S, Nakshabendi I, Lee FD, Sturrock RD, Russell RI \|title=Duodenal histology, ulceration, and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs \|journal=Gut \|volume=34 \|issue=9 \|pages=1162–6 \|year=1993 \|month=September \|pmid=8406146 \|pmc=1375446 \|doi= \|url=}}</ref> thus, without chronic inflammation NSAIDs are unlikely.		**[[NSAID]]s not commonly assoc. with acute inflammation;<ref name=pmid8406146>{{cite journal \|author=Taha AS, Dahill S, Nakshabendi I, Lee FD, Sturrock RD, Russell RI \|title=Duodenal histology, ulceration, and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs \|journal=Gut \|volume=34 \|issue=9 \|pages=1162–6 \|year=1993 \|month=September \|pmid=8406146 \|pmc=1375446 \|doi= \|url=}}</ref> thus, without chronic inflammation NSAIDs are unlikely.
	***Acute NSAID-related duodenitis reported.<ref name=pmid18158085>{{cite journal \|author=Hashash JG, Atweh LA, Saliba T, ''et al.'' \|title=Acute NSAID-related transmural duodenitis and extensive duodenal ulceration \|journal=Clin Ther \|volume=29 \|issue=11 \|pages=2448–52 \|year=2007 \|month=November \|pmid=18158085 \|doi=10.1016/j.clinthera.2007.11.012 \|url=}}</ref>		***Acute NSAID-related duodenitis reported.<ref name=pmid18158085>{{cite journal \|author=Hashash JG, Atweh LA, Saliba T, ''et al.'' \|title=Acute NSAID-related transmural duodenitis and extensive duodenal ulceration \|journal=Clin Ther \|volume=29 \|issue=11 \|pages=2448–52 \|year=2007 \|month=November \|pmid=18158085 \|doi=10.1016/j.clinthera.2007.11.012 \|url=}}</ref>

			===Images===
			<gallery>
			Image: Acute duodenitis -- low mag.jpg \| AD - low mag.
			Image: Acute duodenitis -- intermed mag.jpg \| AD - intermed. mag.
			Image: Acute duodenitis -- high mag.jpg \| AD - high mag.
			Image: Acute duodenitis -- very high mag.jpg \| AD - very high mag.
			</gallery>

	==Sign out==		==Sign out==
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	==See also==		==See also==
	*[[Duodenum]].		*[[Duodenum]].
			*[[Chronic duodenitis]].
			*[[Crohn's disease]].

	==References==		==References==

Michael: split out

2014-04-30T00:16:12Z

split out

← Older revision		Revision as of 00:16, 30 April 2014
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	~~#redirect~~ [[Duodenum~~#Acute_duodenitis~~]]		'''Acute duodenitis''', abbreviated '''AD''', is an acute inflammatory process of the [[duodenum]]. It is relatively uncommon.

			==General==
			DDx:
			*Infection.
			**Helicobactor organisms in the [[stomach]].
			***Helicobacter ''not'' seen unless gastric metaplasia is present.<ref>{{Cite journal \| last1 = Madsen \| first1 = JE. \| last2 = Vetvik \| first2 = K. \| last3 = Aase \| first3 = S. \| title = Helicobacter-associated duodenitis and gastric metaplasia in duodenal ulcer patients. \| journal = APMIS \| volume = 99 \| issue = 11 \| pages = 997-1000 \| month = Nov \| year = 1991 \| doi = \| PMID = 1683540 }}</ref>
			*Medications ([[NSAID]]s).
			*[[Crohn's disease]] (usually focal/patchy).
			*[[Portal hypertension]] (portal hypertensive duodenopathy).<ref name=pmid12003421>{{Cite journal \| last1 = Shudo \| first1 = R. \| last2 = Yazaki \| first2 = Y. \| last3 = Sakurai \| first3 = S. \| last4 = Uenishi \| first4 = H. \| last5 = Yamada \| first5 = H. \| last6 = Sugawara \| first6 = K. \| title = Duodenal erosions, a common and distinctive feature of portal hypertensive duodenopathy. \| journal = Am J Gastroenterol \| volume = 97 \| issue = 4 \| pages = 867-73 \| month = Apr \| year = 2002 \| doi = 10.1111/j.1572-0241.2002.05602.x \| PMID = 12003421 }}</ref>
			*[[Celiac sprue]].

			==Microscopic==
			Features:
			*Intraepithelial lymphocytes.
			*Neutrophils - "found without searching" - '''key feature'''.
			*Eosinophils - "found without searching" - '''key feature'''.
			*Plasma cells (increased).

			Notes:
			*One needs stomach concurrent biopsies to r/o Helicobactor.
			*Erosions make celiac sprue much less likely.
			*Presence of chronic inflammation useful for NSAIDs vs. Helicobacter organisms:
			**[[NSAID]]s not commonly assoc. with acute inflammation;<ref name=pmid8406146>{{cite journal \|author=Taha AS, Dahill S, Nakshabendi I, Lee FD, Sturrock RD, Russell RI \|title=Duodenal histology, ulceration, and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs \|journal=Gut \|volume=34 \|issue=9 \|pages=1162–6 \|year=1993 \|month=September \|pmid=8406146 \|pmc=1375446 \|doi= \|url=}}</ref> thus, without chronic inflammation NSAIDs are unlikely.
			***Acute NSAID-related duodenitis reported.<ref name=pmid18158085>{{cite journal \|author=Hashash JG, Atweh LA, Saliba T, ''et al.'' \|title=Acute NSAID-related transmural duodenitis and extensive duodenal ulceration \|journal=Clin Ther \|volume=29 \|issue=11 \|pages=2448–52 \|year=2007 \|month=November \|pmid=18158085 \|doi=10.1016/j.clinthera.2007.11.012 \|url=}}</ref>

			==Sign out==
			<pre>
			DUODENUM, BIOPSY:
			- ACUTE DUODENITIS.
			</pre>

			===Acute on chronic duodenitis===
			<pre>
			DUODENUM, BIOPSY:
			- ACUTE ON CHRONIC DUODENITIS.
			</pre>

			====Micro====
			The sections show small bowel mucosa with intraepithelial neutrophils. The epithelium shows nuclear hyperchromasia, pseudostratification and nuclear enlargement; however, it matures toward the surface (reactive changes of the epithelium).

			Brunner's glands are found focally in the lamina propria. Gastric foveolar-type epithelium
			is identified. Lamina propria plasma cells are abundant.

			==See also==
			*[[Duodenum]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Duodenum]]

Michael: redirect w/ cat.

2011-10-23T00:49:42Z

redirect w/ cat.

New page

#redirect [[Duodenum#Acute_duodenitis]]

[[Category:Diagnosis]]