View source for Behçet's syndrome

'''Behçet's syndrome''', also '''Behçet's disease''', is a rare disorder classically described as the triad of:<ref name=omim109650>{{OMIM|109650}}</ref>
#Oral aphthous ulcers.
#Genital ulcers.
#Uveitis

==General==
Etiology:
*Unknown - hypothesized to be infectious (due to the epidemiology<ref name=pmid22100288/>) on a background of genetic susceptibility.<ref name=pmid17207160/> 

===Clinical===
*''[[Pathergy]]''<ref name=pmid22100288>{{Cite journal  | last1 = Hatemi | first1 = G. | last2 = Yazici | first2 = H. | title = Behçet's syndrome and micro-organisms. | journal = Best Pract Res Clin Rheumatol | volume = 25 | issue = 3 | pages = 389-406 | month = Jun | year = 2011 | doi = 10.1016/j.berh.2011.05.002 | PMID = 22100288 }}
</ref> = minor trauma (to the skin) results in a non-healing lesion.

==Microscopic==
Features - small vessel [[vasculitis]]:<ref name=pmid22100288/><ref name=pmid17207160>{{Cite journal  | last1 = Kalayciyan | first1 = A. | last2 = Zouboulis | first2 = C. | title = An update on Behçet's disease. | journal = J Eur Acad Dermatol Venereol | volume = 21 | issue = 1 | pages = 1-10 | month = Jan | year = 2007 | doi = 10.1111/j.1468-3083.2006.01863.x | PMID = 17207160 }}</ref>
*[[Fibrinoid necrosis]] of the vessel walls.
*Inflammatory cells in the blood vessel walls.

==See also==
*[[Vasculitides]].

==References==
{{Reflist|2}}

[[Category:Syndromes]]